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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues
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Neuroglia in C. elegans
(Hardcover)
Randy F. Stout Jr, Navin Pokala; Series edited by Alexei Verkhratsky, Vladimir Parpura
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R1,421
Discovery Miles 14 210
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Ships in 10 - 15 working days
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The nematode C. elegans is one of the most important model
organisms for understanding neurobiology. Its completely mapped
neural connectome of 302 neurons and fully characterized and
stereotyped development have made it a prototype for understanding
nervous system structure, development, and function. Fifty-six out
of C. elegans' total of 959 somatic cells are classified as
neuroglia. Although research on worm glia has lagged behind studies
focused on neurons, there has been a steep upswing in interest
during the past decade. Information arising from the recent burst
of research on worm glia supports the idea that C. elegans will
continue to be an important animal model for understanding glial
cell biology. Since the developmental lineage of all cells was
mapped, each glial cell in C. elegans is known by a specific name
and has research associated with it. We list and describe the glia
of the hermaphrodite form of C. elegans and summarize research
findings relating to each glial cell. We hope this lecture provides
an informative overview of worm glia to accompany the excellent and
freely available online resources available to the worm research
community.
Research on natural and artificial brains is proceeding at a rapid
pace. However, the understanding of the essence of consciousness
has changed slightly over the millennia, and only the last decade
has brought some progress to the area. Scientific ideas emerged
that the soul could be a product of the material body and that
calculating machines could imitate brain processes. However, the
authors of this book reject the previously common dualism-the view
that the material and spiritual-psychic processes are separate and
require a completely different substance as their foundation.
Reductive Model of the Conscious Mind is a forward-thinking book
wherein the authors identify processes that are the essence of
conscious thinking and place them in the imagined, simplified
structure of cells able to memorize and transmit information in the
form of impulses, which they call neurons. The purpose of the study
is to explain the essence of consciousness to the degree of
development of natural sciences, because only the latter can find a
way to embed the concept of the conscious mind in material brains.
The book is divided into three parts. Part 1 works to convince
readers that the emergence of consciousness does not require
detailed knowledge of the structure and morphology of the brain,
with the exception of some specific properties of the neural
network structure that the authors attempt to point out. Part 2
proves that the biological structure of many natural brains
fulfills the necessary conditions for consciousness and intelligent
thinking. Similarly, Part 3 shows the ways in which artificial
creatures imitating natural brains can meet these conditions, which
gives great hopes for building artificially intelligent beings
endowed with consciousness. Covering topics that include cognitive
architecture, the embodied mind, and machine learning, this book is
ideal for cognitive scientists, philosophers of mind,
neuroscientists, psychologists, researchers, academicians, and
advanced-level students. The book can also help to focus the
research of linguists, neurologists, and biophysicists on the
biophysical basis of postulated information processing into
knowledge structures.
This is a tale of human obsession, one intrepid tuna, the dedicated
fisherman who caught and set her free, the promises and limits of
ocean science and the big truth of how our insatiable appetite for
bluefin transformed a cottage industry into a global dilemma. In
2004, an enigmatic charter captain named Al Anderson caught and
marked one Atlantic bluefin tuna off New England’s coast with a
plastic fish tag. Fourteen years later that fish – dubbed Amelia
for her ocean-spanning journeys – died in a Mediterranean fish
trap, sparking Karen Pinchin’s riveting investigation into the
marvels, struggles, and prehistoric legacy of this remarkable
species. Over his fishing career Al marked more than sixty thousand
fish with plastic tags, an obsession that made him nearly as many
enemies as it did friends. His quest landed him in the crossfire of
an ongoing fight between a booming bluefin tuna industry and
desperate conservation efforts, a conflict that is once again
heating up as overfishing and climate change threaten the fish’s
fate. Kings of Their Own Ocean is an urgent investigation that
combines science, business, crime, and environmental justice. As
Pinchin writes, ‘as a global community, we are collectively only
ever a few terrible choices away from wiping out any ocean
species.’ Through her exclusive access and interdisciplinary,
mesmerizing lens, readers will join her on boats and docks as she
visits tuna hot spots and scientists from Portugal to Japan, New
Jersey to Nova Scotia, and glimpse, as the author does, rays of
dazzling hope for the future of our oceans.
The book highlights important new research approaches of clinical
relevance, written by prominent researchers in the field of OCD and
related disorders. A broad range of topics is covered, beginning
with a description of the phenotypic features of the OCD followed
by chapters on developmental aspects, animal models, genetic and
biological models including neuro-inflammation, functional
neuroimaging correlates and information-processing accounts.
Finally, existing and novel treatment approaches are covered
including clinical and pharmacogenetic treatment models. In this
way the volume brings together the key disciplines involved in the
neurobiological understanding of OCD to provide an update of the
field and outlook to the future. Together, the volume chapters
provide focused and critical reviews that span a broad range of
topics suitable for both students and established investigators and
clinicians interested in the present state of OCD research.
This book explores new developments in the dialogues between
science and theatre and offers an introduction to a fast-expanding
area of research and practice.The cognitive revolution in the
humanities is creating new insights into the audience experience,
performance processes and training. Scientists are collaborating
with artists to investigate how our brains and bodies engage with
performance to create new understanding of perception, emotion,
imagination and empathy. Divided into four parts, each introduced
by an expert editorial from leading researchers in the field, this
edited volume offers readers an understanding of some of the main
areas of collaboration and research: 1. Dances with Science 2.
Touching Texts and Embodied Performance 3. The Multimodal Actor 4.
Affecting Audiences Throughout its history theatre has provided
exciting and accessible stagings of science, while contemporary
practitioners are increasingly working with scientific and medical
material. As Honour Bayes reported in the Guardian in 2011, the
relationships between theatre, science and performance are
'exciting, explosive and unexpected'. Affective Performance and
Cognitive Science charts new directions in the relations between
disciplines, exploring how science and theatre can impact upon each
other with reference to training, drama texts, performance and
spectatorship. The book assesses the current state of play in this
interdisciplinary field, facilitating cross disciplinary exchange
and preparing the way for future studies.
Landraces possess a very large genetic base in population structure
and are dynamic populations of cultivated plants with historical
origin, distinct identity, and without any formal crop improvement.
They are often genetically diverse, locally adapted, and associated
with traditional farming systems. Resistance genes to biotic and
abiotic stress factors, which are especially diversified in
landraces, are of great interest to plant breeders, faced with
global climate challenge. In addition, gene pools made of different
landraces grown in different ecological conditions can be used for
wheat breeding to enhance quality; yield and other desirable
agricultural parameters. An estimated 75% of the genetic diversity
of crop plants was lost in the last century due to the replacement
of high yielding modern varieties. There is, thus, an urgent need
to preserve existing species, not only for posterity but also as a
means to secure food supply for a rising world population. In this
book, we provide an overview of wheat landraces with special
attention to genetic diversities, conservation, and utilization.
This book discusses the role of genetic polymorphism in
susceptibility to cancers. The book explores the understanding of
differences between the genetic polymorphisms and mutations.It
reviews the mechanisms underlying the effect of polymorphism in
genes encoding proteins that play an essential role in metabolism,
signal transduction, cell cycle, and DNA repair mechanisms.
Further, it investigates various techniques that are used for
analyzing the genetic polymorphisms. The book contains many
chapters which summarize the importance of genetic information
obtained from polymorphism-based pharmaco-genetic tests to predict
better drug response and life-threatening adverse reactions to
chemotherapeutic agents, help in understanding of the impact of
SNPs on gene function, and gives overview of the different SNP
databases for examination. This book, therefore, serves as an
essential guidebook for independent researchers as well as
institutions working in this specialised field.
Brain network function and dysfunction is the dominant model for
understanding how the brain gives rise to normal and abnormal
behavior. Moreover, neuropsychiatric illnesses continue to resist
attempts to reveal an understanding of their bases. Thus, this
timely volume provides a synthesis of the uses of multiple analytic
methods as they are applied to neuroimaging data, to seek
understanding of the neurobiological bases of psychiatric
illnesses, understanding that can subsequently aid in their
management and treatment. A principle focus is on the analyses and
application of methods to functional magnetic resonance imaging
(fMRI) data. fMRI remains the most widely used neuroimaging
technique for estimating brain network function, and several of the
methods covered can estimate brain network dysfunction in resting
and task-active states. Additional chapters provide details on how
these methods are (and can be) applied in the understanding of
several neuropsychiatric disorders, including schizophrenia, mood
disorders, autism, borderline personality disorder, and attention
deficit hyperactivity disorder (ADHD). A final complement of
chapters provides a collective overview of how this framework
continues to provoke theoretical advances in our conception of the
brain in psychiatry. This unique volume is designed to be a
comprehensive resource for imaging researchers interested in
psychiatry, and for psychiatrists interested in advanced imaging
applications.
This edited collection brings together internationally recognized
experts in a range of areas of statistical science to honor the
contributions of the distinguished statistician, Barry C. Arnold. A
pioneering scholar and professor of statistics at the University of
California, Riverside, Dr. Arnold has made exceptional advancements
in different areas of probability, statistics, and biostatistics,
especially in the areas of distribution theory, order statistics,
and statistical inference. As a tribute to his work, this book
presents novel developments in the field, as well as practical
applications and potential future directions in research and
industry. It will be of interest to graduate students and
researchers in probability, statistics, and biostatistics, as well
as practitioners and technicians in the social sciences, economics,
engineering, and medical sciences.
The state of Sao Paulo, Brazil, is one of the most densely
populated and developed areas in South America. Such development is
evident both in terms of industrialization and urbanization, as
well as in agriculture, which is heavily based on sugar cane,
Eucalyptus plantations and livestock. This intense land use has
resulted in great alteration of the original land cover and
fragmentation of natural ecosystems. For these reasons, it is
almost a paradox that jaguar, a species that requires large areas
of pristine forest to exist, is still found in some parts of the
state of Sao Paulo. It is possible that wild animals could leave in
coexistence with intense land use, or is it the case that such rare
encounters with large wild animals in Sao Paulo will disappear in
the near future? All ecologists are aware of the problems of
habitat changes caused by humans, but it was not until recent years
that researchers started to consider that the land used for
production could also serve as an important habitat for many
different kinds of wild species. This book is about this new
approach to conservation. It also highlights the important role
that sciences could and should have in this discussion in order to
better understand the problems and propose possible solutions.
Neuroprosthetics is a fast-growing area that brings together the
fields of biomedical engineering and neuroscience as a means to
interface the neural system directly to prostheses. Advancing
research and applications in this field can assist in successfully
restoring motor, sensory, and cognitive functions. Emerging Theory
and Practice in Neuroprosthetics brings together the most
up-to-date research surrounding neuroprosthetics advances and
applications. Presenting several new results, concepts, and further
developments in the area of neuroprosthetics, this book is an
essential publication for researchers, upper-level students,
engineers, and medical practitioners.
Evolution, Chance, and God looks at the relationship between
religion and evolution from a philosophical perspective. This
relationship is fascinating, complex and often very controversial,
involving myriad issues that are difficult to keep separate from
each other. Evolution, Chance, and God introduces the reader to the
main themes of this debate and to the theory of evolution, while
arguing for a particular viewpoint, namely that evolution and
religion are compatible, and that, contrary to the views of some
influential thinkers, there is no chance operating in the theory of
evolution, a conclusion that has great significance for teleology.
One of the main aims of this book is not simply to critique one
influential contemporary view that evolution and religion are
incompatible, but to explore specific ways of how we might
understand their compatibility, as well as the implications of
evolution for religious belief. This involves an exploration of how
and why God might have created by means of evolution, and what the
consequences in particular are for the status of human beings in
creation, and for issues such as free will, the objectivity of
morality, and the problem of evil. By probing how the theory of
evolution and religion could be reconciled, Sweetman says that we
can address more deeply key foundational questions concerning
chance, design, suffering and morality, and God's way of acting in
and through creation.
This book describes the alarming condition of agriculture in the
Anthropocene, when the ethical conception of agriculture as a
service of common utility for both society and environment has
progressively been marginalized. The ethical utility of agriculture
has been sidetracked with the increasing industrialisation of
society, the involvement of agriculture in the business-as-usual
economy, and the consequential environmental and societal impacts
it has had. Thus, re-establishing a meaningful bridge between
ethics and agriculture is necessary. A relatively new science
(ecology) with both a new epistemological tool (that of the
ecosystem concept), and a unique narrative of sustainable
development, can help bridge this gap. This book focuses on ethics
as a lever for raising scientific, technical, social, economic and
political solutions to adopt in agriculture as a model of symbiotic
relationships between man and nature. It provides a detailed
discussion of the ecological intensification practices in order to
maximize ecological and ethical services, wherein agroecosystems
will follow.
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