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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues

Back to Reality (Hardcover): Arto Annila Back to Reality (Hardcover)
Arto Annila
R964 Discovery Miles 9 640 Ships in 12 - 19 working days
Problem of Increasing Human Energy - With Special Reference to the Harnessing of the Sun's Energy (Hardcover): Nikola Tesla Problem of Increasing Human Energy - With Special Reference to the Harnessing of the Sun's Energy (Hardcover)
Nikola Tesla
R552 Discovery Miles 5 520 Ships in 10 - 15 working days
Synucleins - Biochemistry and Role in Diseases (Hardcover): Andrei Surguchov Synucleins - Biochemistry and Role in Diseases (Hardcover)
Andrei Surguchov
R2,686 Discovery Miles 26 860 Ships in 10 - 15 working days
Tree Story - The History of the World Written in Rings (Paperback): Valerie Trouet Tree Story - The History of the World Written in Rings (Paperback)
Valerie Trouet
R509 R480 Discovery Miles 4 800 Save R29 (6%) Ships in 10 - 15 working days

What if the stories of trees and people are more closely linked than we ever imagined? Winner of the World Wildlife Fund's 2020 Jan Wolkers PrizeOne of Science News's "Favorite Books of 2020" A New York Times "New and Noteworthy" BookA 2020 Woodland Book of the YearGold Winner of the 2020 Foreword INDIES Award in Ecology & EnvironmentBronze Winner of the 2021 Independent Publisher Book Award in Environment/Ecology People across the world know that to tell how old a tree is, you count its rings. Few people, however, know that research into tree rings has also made amazing contributions to our understanding of Earth's climate history and its influences on human civilization over the past 2,000 years. In her captivating book Tree Story, Valerie Trouet reveals how the seemingly simple and relatively familiar concept of counting tree rings has inspired far-reaching scientific breakthroughs that illuminate the complex interactions between nature and people. Trouet, a leading tree-ring scientist, takes us out into the field, from remote African villages to radioactive Russian forests, offering readers an insider's look at tree-ring research, a discipline known as dendrochronology. Tracing her own professional journey while exploring dendrochronology's history and applications, Trouet describes the basics of how tell-tale tree cores are collected and dated with ring-by-ring precision, explaining the unexpected and momentous insights we've gained from the resulting samples. Blending popular science, travelogue, and cultural history, Tree Story highlights exciting findings of tree-ring research, including the fate of lost pirate treasure, successful strategies for surviving California wildfire, the secret to Genghis Khan's victories, the connection between Egyptian pharaohs and volcanoes, and even the role of olives in the fall of Rome. These fascinating tales are deftly woven together to show us how dendrochronology sheds light on global climate dynamics and uncovers the clear links between humans and our leafy neighbors. Trouet delights us with her dedication to the tangible appeal of studying trees, a discipline that has taken her to austere and beautiful landscapes around the globe and has enabled scientists to solve long-pondered mysteries of Earth and its human inhabitants.

Religion and Human Enhancement - Death, Values, and Morality (Hardcover, 1st ed. 2017): Tracy J. Trothen, Calvin Mercer Religion and Human Enhancement - Death, Values, and Morality (Hardcover, 1st ed. 2017)
Tracy J. Trothen, Calvin Mercer
R5,358 Discovery Miles 53 580 Ships in 12 - 19 working days

This collection vigorously addresses the religious implications of extreme human enhancement technology. Topics covered include cutting edge themes, such as moral enhancement, common ground to both transhumanism and religion, the meaning of death, desire and transcendence, and virtue ethics. Radical enhancement programs, advocated by transhumanists, could arguably have a more profound impact than any other development in human history. Reflecting a range of opinion about the desirability of extreme enhancement, leading scholars in the field join with emerging scholars to foster enhanced conversation on these topics.

Developing Solid Oral Dosage Forms - Pharmaceutical Theory and Practice (Hardcover, 2nd edition): Yihong Qiu, Yisheng Chen,... Developing Solid Oral Dosage Forms - Pharmaceutical Theory and Practice (Hardcover, 2nd edition)
Yihong Qiu, Yisheng Chen, Geoff G. Z. Zhang, Lawrence Yu, Rao V. Mantri
R7,324 R6,499 Discovery Miles 64 990 Save R825 (11%) Ships in 12 - 19 working days

Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preformulation investigation, formulation, process design, characterization, scale-up, and production operations. This book covers the essential principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their application to the research and development process of oral dosage forms. Chapters have been added, combined, deleted, and completely revised as necessary to produce a comprehensive, well-organized, valuable reference for industry professionals and academics engaged in all aspects of the development process. New and important topics include spray drying, amorphous solid dispersion using hot-melt extrusion, modeling and simulation, bioequivalence of complex modified-released dosage forms, biowaivers, and much more.

Alien Information Theory - Psychedelic Drug Technologies and the Cosmic Game (Hardcover, Harcover Ed.): Andrew R Gallimore Alien Information Theory - Psychedelic Drug Technologies and the Cosmic Game (Hardcover, Harcover Ed.)
Andrew R Gallimore
R812 Discovery Miles 8 120 Ships in 12 - 19 working days
Neural Control of Blood Pressure and Body Temperature During Heat Stress (Hardcover): Zachary J Schlader, Nisha Charkoudian Neural Control of Blood Pressure and Body Temperature During Heat Stress (Hardcover)
Zachary J Schlader, Nisha Charkoudian; Series edited by D. Neil Granger, Joey P Granger
R1,839 Discovery Miles 18 390 Ships in 10 - 15 working days

Environmental heat stress is associated with a marked decrease in orthostatic tolerance (OT), which is defined as the ability to stand or sit upright without symptoms of dizziness, lightheadedness, presyncope, or fainting. In most healthy humans, the autonomic nervous system makes rapid and balanced adjustments to heart rate and peripheral blood flow, such that most people are able to stand up "successfully" most of the time, in most environments. The goal of this book is to discuss various aspects of the sympathetic neural response to heat stress, how the sympathetic nervous system coordinates the successful integrative physiological response to orthostasis, and what happens when it encounters both challenges simultaneously. We include overviews of mechanisms of thermoregulation and blood pressure regulation in humans, with particular focus on control of cardiac output and neurovascular control mechanisms during heat stress. We discuss the implications that these changes have for distribution of peripheral blood flow and, in particular, for blood flow to the cerebral circulation. The added stressor of dehydration is also discussed, as it so often goes hand in hand with heat stress. We end with a brief presentation of countermeasures against the decreases in OT with heat stress.

Microbial Technology (Hardcover): R Puvanakrishnan, S Sivasubramanian, T. Hemalatha Microbial Technology (Hardcover)
R Puvanakrishnan, S Sivasubramanian, T. Hemalatha
R1,454 Discovery Miles 14 540 Ships in 10 - 15 working days
Translating MicroRNAs to the Clinic (Hardcover): Jeffrey Laurence Translating MicroRNAs to the Clinic (Hardcover)
Jeffrey Laurence
R2,849 R2,678 Discovery Miles 26 780 Save R171 (6%) Ships in 12 - 19 working days

Translating microRNA to the Clinic reviews the possibilities of current methodological tools and experimental approaches used by leading translational researchers. The book features the uses of micro ribonucleic acid as deployed in cancer targeting in biomarkers, diabetes, cardiovascular disease, and neurodegeneration, among many others. Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field, promoting a cross-disciplinary communication between the sub-specialities of medicine, but in common with other books on the topic. In addition, the book emphasizes recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole.

On Human Nature - Biology, Psychology, Ethics, Politics, and Religion (Hardcover): Michel Tibayrenc, Francisco J. Ayala On Human Nature - Biology, Psychology, Ethics, Politics, and Religion (Hardcover)
Michel Tibayrenc, Francisco J. Ayala
R3,285 Discovery Miles 32 850 Ships in 12 - 19 working days

On Human Nature: Biology, Psychology, Ethics, Politics, and Religion covers the present state of knowledge on human diversity and its adaptative significance through a broad and eclectic selection of representative chapters. This transdisciplinary work brings together specialists from various fields who rarely interact, including geneticists, evolutionists, physicians, ethologists, psychoanalysts, anthropologists, sociologists, theologians, historians, linguists, and philosophers. Genomic diversity is covered in several chapters dealing with biology, including the differences in men and apes and the genetic diversity of mankind. Top specialists, known for their open mind and broad knowledge have been carefully selected to cover each topic. The book is therefore at the crossroads between biology and human sciences, going beyond classical science in the Popperian sense. The book is accessible not only to specialists, but also to students, professors, and the educated public. Glossaries of specialized terms and general public references help nonspecialists understand complex notions, with contributions avoiding technical jargon.

Handbook of Basal Ganglia Structure and Function, Volume 24 (Hardcover, 2nd edition): Heinz Steiner, Kuei Y. Tseng Handbook of Basal Ganglia Structure and Function, Volume 24 (Hardcover, 2nd edition)
Heinz Steiner, Kuei Y. Tseng
R4,354 R3,841 Discovery Miles 38 410 Save R513 (12%) Ships in 12 - 19 working days

Handbook of Basal Ganglia Structure and Function, Second Edition, offers an integrated overview of the structural and functional aspects of the basal ganglia, highlighting clinical relevance. The basal ganglia, a group of forebrain nuclei interconnected with the cerebral cortex, thalamus, and brainstem, are involved in numerous brain functions, such as motor control and learning, sensorimotor integration, reward, and cognition. These nuclei are essential for normal brain function and behavior, and their importance is further emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson's disease, Tourette's syndrome, Huntington's disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. This updated edition has been thoroughly revised to provide the most up-to-date account of this critical brain structure. Edited and authored by internationally acclaimed basal ganglia researchers, the new edition contains ten entirely new chapters that offer expanded coverage of anatomy and physiology, detailed accounts of recent advances in cellular/molecular mechanisms and cellular/physiological mechanisms, and critical, deeper insights into the behavioral and clinical aspects of basal ganglia function and dysfunction.

Neuroepidemiology, Volume 138 (Hardcover): Caterina Rosano, M. Arfan Ikram, Mary Ganguli Neuroepidemiology, Volume 138 (Hardcover)
Caterina Rosano, M. Arfan Ikram, Mary Ganguli
R5,830 R5,392 Discovery Miles 53 920 Save R438 (8%) Ships in 12 - 19 working days

Neuroepidemiology covers the foundations of neuroepidemiological research and the epidemiology of disorders primarily affecting the nervous system, as well as those originating outside the nervous system. The etiology of many important central nervous system disorders remains elusive. Even with diseases where the key risk determinants have been identified, better prevention and therapy is needed to reduce high incidence and mortality. Although evolving technologies for studying disease provide opportunities for such, it is essential for researchers and clinicians to understand how best to apply such technology in the context of carefully characterized patient populations. By paying special attention to methodological approaches, this volume prepares new investigators from a variety of disciplines to conduct epidemiological studies in order to discern the etiologic factors and underlying mechanisms that influence the onset, progression, and recurrence of CNS disorders and diseases. The book also provides current information on methodological approaches for clinical neurologists seeking to expand their knowledge in research.

Practical Problem with Solution in Waste Water Engineering Vol. 5 (Hardcover): D.R. Saini, S.N. Kaul, Prateek Kaul Practical Problem with Solution in Waste Water Engineering Vol. 5 (Hardcover)
D.R. Saini, S.N. Kaul, Prateek Kaul
R9,556 R9,048 Discovery Miles 90 480 Save R508 (5%) Ships in 10 - 15 working days
Chromatin Signaling and Diseases (Hardcover): Olivier Binda, Martin Ernesto Fernandez-Zapico Chromatin Signaling and Diseases (Hardcover)
Olivier Binda, Martin Ernesto Fernandez-Zapico
R3,114 R2,925 Discovery Miles 29 250 Save R189 (6%) Ships in 12 - 19 working days

Chromatin Signaling and Diseases covers the molecular mechanisms that regulate gene expression, which govern everything from embryonic development, growth, and human pathologies associated with aging, such as cancer. This book helps researchers learn about or keep up with the quickly expanding field of chromatin signaling. After reading this book, clinicians will be more capable of explaining the mechanisms of gene expression regulation to their patients to reassure them about new drug developments that target chromatin signaling mechanisms. For example, several epigenetic drugs that act on chromatin signaling factors are in clinical trials or even approved for usage in cancer treatments, Alzheimer's, and Huntington's diseases. Other epigenetic drugs are in development to regulate various class of chromatin signaling factors. To keep up with this changing landscape, clinicians and doctors will need to stay familiar with genetic advances that translate to clinical practice, such as chromatin signaling. Although sequencing of the human genome was completed over a decade ago and its structure investigated for nearly half a century, molecular mechanisms that regulate gene expression remain largely misunderstood. An emerging concept called chromatin signaling proposes that small protein domains recognize chemical modifications on the genome scaffolding histone proteins, facilitating the nucleation of enzymatic complexes at specific loci that then open up or shut down the access to genetic information, thereby regulating gene expression. The addition and removal of chemical modifications on histones, as well as the proteins that specifically recognize these, is reviewed in Chromatin Signaling and Diseases. Finally, the impact of gene expression defects associated with malfunctioning chromatin signaling is also explored.

Neural Control of Renal Function (Hardcover, 2nd Revised edition): Ulla C. Kopp Neural Control of Renal Function (Hardcover, 2nd Revised edition)
Ulla C. Kopp; Series edited by D. Neil Granger, Joey P Granger
R1,962 Discovery Miles 19 620 Ships in 10 - 15 working days

The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of 1-adrenoceptors and increase renin secretion rate by activation of 1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic tissue of a magnitude that may occur during increased urine flow rate. Under normal conditions, the renal mechanosensory nerves activated by stretch of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension.

Obesity and Esophageal Disorders (Paperback): Dhyanesh Patel, Robert Kavitt, Shabnam Sarker, Michael Vaezi Obesity and Esophageal Disorders (Paperback)
Dhyanesh Patel, Robert Kavitt, Shabnam Sarker, Michael Vaezi
R3,426 Discovery Miles 34 260 Ships in 12 - 19 working days

Obesity and Esophageal Disorders is a comprehensive review on the impact of obesity on esophageal disorders and how to approach, recognize and treat those disorders. Covering the critical gap in awareness on the impact of obesity on esophageal disorders, this reference presents the newest diagnostic technologies, including high resolution manometry, EndoFLIP, wireless pH monitoring, and mucosal integrity devices. The book shows treatment options like bariatric surgery and endo-bariatrics that decrease the latency period for diagnosis and management of patients. Finally, the understanding of the potential effects of different bariatric surgeries on esophageal motility is explored. This importance reference serves researchers looking to determine future projects by providing novel pathophysiologic mechanisms about how obesity affects GERD and esophageal motility. It serves clinicians, surgeons and trainees with guidance on diagnostic approaches, management options, and how to recognize/treat post-surgical esophageal complications of patients with obesity.

Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods, Volume 105 (Hardcover): Christo... Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods, Volume 105 (Hardcover)
Christo Christov
R4,983 R4,172 Discovery Miles 41 720 Save R811 (16%) Ships in 12 - 19 working days

Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods is the latest volume in the popular Advances in Protein Chemistry and Structural Biology series, an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

Na Channels from Phyla to Function, Volume 78 (Hardcover): Sergei Noskov, Robert J French Na Channels from Phyla to Function, Volume 78 (Hardcover)
Sergei Noskov, Robert J French
R5,659 R4,745 Discovery Miles 47 450 Save R914 (16%) Ships in 12 - 19 working days

Na Channels from Phyla to Function, the latest volume in the Current Topics in Membranes series, is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume offers an up-to-date presentation of the current knowledge in the field of Na Channels.

Concise Encyclopedia of Brain and Language (Paperback): Harry A. Whitaker Concise Encyclopedia of Brain and Language (Paperback)
Harry A. Whitaker
R3,970 R3,701 Discovery Miles 37 010 Save R269 (7%) Ships in 12 - 19 working days

This volume descibes, in up-to-date terminology and authoritative interpretation, the field of neurolinguistics, the science concerned with the neural mechanisms underlying the comprehension, production and abstract knowledge of spoken, signed or written language. An edited anthology of 165 articles from the award-winning Encyclopedia of Language and Linguistics 2nd edition, Encyclopedia of Neuroscience 4th Edition and Encyclopedia of the Neorological Sciences and Neurological Disorders, it provides the most comprehensive one-volume reference solution for scientists working with language and the brain ever published.

Immunology, Inflammation and Diseases of the Eye (Paperback): Darlene A. Dartt, Reza Dana, Patricia D'Amore, Jerry... Immunology, Inflammation and Diseases of the Eye (Paperback)
Darlene A. Dartt, Reza Dana, Patricia D'Amore, Jerry Niederkorn
R3,050 Discovery Miles 30 500 Ships in 12 - 19 working days

This selection of articles from the Encyclopedia of the Eye provides a comprehensive overview of immunological features, diseases and inflammation of the eye and its support structures and organs. Rather than taking an immunological focus that is strictly suitable for clinicians, the volume offers a considerable basic science background and addresses a broad range of topics - the immune system of the eye, its various disorders, mechanisms of inflammation of the eye and visual system, treatment, wound healing mechanisms, stem cells, and more.

Ocular Periphery and Disorders (Paperback): Darlene A. Dartt, Peter Bex, Patricia D'Amore, Reza Dana, Linda Mcloon, Jerry... Ocular Periphery and Disorders (Paperback)
Darlene A. Dartt, Peter Bex, Patricia D'Amore, Reza Dana, Linda Mcloon, …
R3,066 Discovery Miles 30 660 Ships in 12 - 19 working days

This selection of articles from the Encyclopedia of the Eye is the first single-volume overview presenting articles on the function, biology, physiology, and pathology of the structures of the ocular periphery, as well as the related disorders and their treatment. The peripheral structures are implicated in a number of important diseases, including optic neuritis, thyroid eye disease, and strabismus. The volume offers a basic science background of these topics rather than a strictly clinical focus.

Concepts and Techniques in Genomics and Proteomics (Paperback): N. Saraswathy, P Ramalingam Concepts and Techniques in Genomics and Proteomics (Paperback)
N. Saraswathy, P Ramalingam
R2,245 R2,125 Discovery Miles 21 250 Save R120 (5%) Ships in 12 - 19 working days

Concepts and techniques in genomics and proteomics covers the important concepts of high-throughput modern techniques used in the genomics and proteomics field. Each technique is explained with its underlying concepts, and simple line diagrams and flow charts are included to aid understanding and memory. A summary of key points precedes each chapter within the book, followed by detailed description in the subsections. Each subsection concludes with suggested relevant original references.

River Ecosystem Ecology - A Global Perspective (Paperback): Gene E. Likens River Ecosystem Ecology - A Global Perspective (Paperback)
Gene E. Likens
R2,050 Discovery Miles 20 500 Ships in 12 - 19 working days

A derivative of the Encyclopedia of Inland Waters, River Ecosystem Ecology reviews the function of rivers and streams as ecosystems as well as the varied activities and interactions that occur among their abiotic and biotic components. Because the articles are drawn from an encyclopedia, the articles are easily accessible to interested members of the public, such as conservationists and environmental decision makers.

Biogeochemistry of Inland Waters (Paperback): Gene E. Likens Biogeochemistry of Inland Waters (Paperback)
Gene E. Likens
R3,399 Discovery Miles 33 990 Ships in 12 - 19 working days

A derivative of the Encyclopedia of Inland Waters, Biogeochemistry of Inland Waters examines the transformation, flux and cycling of chemical compounds in aquatic and terrestrial ecosystems, combining aspects of biology, ecology, geology, and chemistry. Because the articles are drawn from an encyclopedia, they are easily accessible to interested members of the public, such as conservationists and environmental decision makers.

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