The evolution of a classic The new 12th edition of Introduction to Genetic Analysis takes this cornerstone textbook to the next level. The hallmark focuses on genetic analysis, quantitative problem solving, and experimentation continue in this new edition while incorporating robust updates to the science. Introduction to Genetic Analysis is now supported in Achieve, Macmillan's new online learning platform. Achieve is the culmination of years of development work put toward creating the most powerful online learning tool for biology students. It houses all of our renowned assessments, multimedia assets, e-books, and instructor resources in a powerful new platform.

An all-in-one guide for helping caregivers of individuals with brain injury or degenerative disease to address speech, language, voice, memory, and swallowing impairment and to distinguish these problem areas from healthy aging. Advances in science mean that people are more likely to survive a stroke or live for many years after being diagnosed with a degenerative disease such as Parkinson's. But the communication deficits that often accompany a brain injury or chronic neurologic condition-including problems with speech, language, voice, memory, and/or swallowing-can severely impact quality of life. If you are a caregiver coping with these challenges, this all-in-one book can help you and your loved one. Written by a team of experts in speech-language pathology, each chapter focuses on a different aspect of caregiving and features relatable patient examples. Providing answers to common questions, definitions of complex medical terms, and lists of helpful resources, this book also: * touches on expected, age-related changes in communication, memory, swallowing, and hearing abilities, to name a few * offers practical strategies for caregivers to cope with speech, language, and voice problems and to maximize their loved one's ability to communicate * reveals how caregivers can assist their loved ones with swallowing challenges to maintain good nutrition and hydration * provides crucial information on how caregivers can handle grief and take care of themselves during the caregiving process * explains how to incorporate the arts, as well as a loved one's hobbies and interests, into their communication or memory recovery This comprehensive book will allow readers to take a more informed and active role in their loved one's care. Contributors: Marissa Barrera, Frederick DiCarlo, Lea Kaploun, Elizabeth Roberts, Teresa Signorelli Pisano

The book presents nine mini-courses from a summer school, Dynamics of Biological Systems, held at the University of Alberta in 2016, as part of the prestigious seminar series: Seminaire de Mathematiques Superieures (SMS). It includes new and significant contributions in the field of Dynamical Systems and their applications in Biology, Ecology, and Medicine. The chapters of this book cover a wide range of mathematical methods and biological applications. They - explain the process of mathematical modelling of biological systems with many examples, - introduce advanced methods from dynamical systems theory, - present many examples of the use of mathematical modelling to gain biological insight - discuss innovative methods for the analysis of biological processes, - contain extensive lists of references, which allow interested readers to continue the research on their own. Integrating the theory of dynamical systems with biological modelling, the book will appeal to researchers and graduate students in Applied Mathematics and Life Sciences.

There has recently been considerable discussion of a "replication crisis" in some areas of science. In this book, the authors argue that replication is not a necessary criterion for the validation of a scientific experiment. Five episodes from physics and genetics are used to substantiate this thesis: the Meselson-Stahl experiment on DNA replication, the discoveries of the positron and the omega minus hyperon, Mendel's plant experiments, and the discovery of parity nonconservation. Two cases in which once wasn't enough are also discussed, the nondiscovery of parity nonconservation and the search for magnetic monopoles. Reasons why once wasn't enough are also discussed.

This book presents the discourse in Jewish law and rabbinic literature on bioethical issues, highlighting practical problems in their socio-historical contexts. Yechiel Michael Barilan discusses end-of-life care, abortion, infertility treatments, the brain death debate, and the organ market. Barilan also presents the theology and spirituality of Jewish medical law, the communal responsibility for healthcare, and the charitable sick-care societies that flourished in the Jewish communities until the beginning of the twentieth century.

This book addresses "phyto-microbiome mediated stress regulation". Fundamentally speaking, the microbial community's importance for the survival of plants under stress conditions has already been confirmed. This book focuses on the roles of those rhizospheric microbiomes that are advantageous to plant developmental pathways. Gathering contributions by authors with specialized expertise in plant growth and health under stress conditions, as well as opportunistic pathogenic bacteria, the book reviews the functional aspects of rhizospheric microorganisms and how they impact plant health and disease. It offers a compendium of plant and microbial interactions at the level of multitrophic interactions, and identifies gaps between future demand and present research on plant stress. In closing, the authors highlight several directions for reshaping rhizosphere microbiomes in favor of microorganisms that are beneficial to plant growth and health.

This book constitutes a fascinating and in-depth analysis of the significance of the requirement of industrial application within gene patenting and how this influences innovation in Europe and the US. The author addresses an area normally overlooked in biotechnology patenting due to the predominance of the ethical debate and, in doing so, produces a unique approach to dealing with concerns in this field. Patenting Genes: The Requirement of Industrial Application is the result of extensive research into the legal history of the industrial application requirement as well as exploration of the broad range of decisions on DNA patentability. This requirement has taken a prominent role within DNA patenting decisions in Europe since the 1998 Biotech Directive, which Dr Diaz Pozo argues has worked efficiently to control claims to human gene sequences and encouraged progress in genetic research. A broad selection of decisions on the patentability of DNA in both European Union and US courts is discussed, emphasizing the mirroring of the European approach in US cases. Academics and students of patent law and biotechnology innovation, as well as policy formulators, will find this book of great interest and value. Activists and practitioners interested in the patentability of human gene inventions in Europe and the US will also benefit from this original work.

This book reviews all important aspects of dietary research associated with cancer with the aim of shedding new light on these conditions through combined understanding of traditional and new paradigms. The book is divided into 17 chapters, the first portion reinterprets healthy diets for cancer based on up-to-date evidence from a network science perspective, examining the dietary patterns, outcome of diet related clinical trials, emerging framework of molecular mechanisms and interactions of dietary interventions and their applications in personalized diet, ground realities of benefits and regulatory frame work for functional foods, nutraceuticals and supplements in cancer prevention and upcoming future prospectus in diet-cancer research.. The later part of the book discusses recent advances in understanding of the elaborative discourse on cancer and fasting, covering, for example, calorie restriction and fasting mimicking diet. Finally, different Dietary research and approaches are considered in the context of novel intervention for cancer research. Dietary Research in Cancer will be of interest for all researchers, nutritionists, students and clinicians in the field.

This book brings together the most recent advances from leading experts in the burgeoning field of environmental biotechnology. The contributing chapters adopt a multidisciplinary approach related to environmental aspects of agriculture, industry, pharmaceutical sciences and drug developments from plant and microbial sources, biochemical chemical techniques/methods/protocols involved in different areas of environmental biotechnology. Book also highlights recent advancements, newly emerging technologies, and thought provoking approaches from different parts of the world. It also discusses potential future prospects associated with some frontier development of biotechnological research related to the environment. This book will be of interest to teachers, researchers, biotechnologists, capacity builders and policymakers, and will serve as additional reading material for undergraduate and graduate students of biotechnology, microbiology and environmental sciences.

The aim of this book is not only to introduce readers with a broad spectrum of biological actions of the NOP receptor, but also to feature a detailed look at the N/OFQ-NOP receptor system, medicinal chemistry, pharmacology, and clinical data of NOP-targeted ligands. This special volume book - for the first time focusing on the NOP receptor - is designed to serve as a useful reference, stimulate more research on the N/OFQ-NOP receptor system, and lead to more development of NOP-related ligands for several therapeutic applications.

Since the first edition of the Aging Auditory System volume (in 2009), there has been a tremendous amount of research in basic, translational, and clinical sciences related to age-related changes in auditory system structure and function. The new research has been driven by technical and conceptual advances in auditory neuroscience at multiple levels ranging from cells to cognition. The chapters in Aging and Hearing: Causes and Consequences span a broad range of topics and appeal to a relatively wide audience. Our goal in this volume is to put together state-of-the-art discussions about new developments in aging research that will appeal to a broad audience, serving as an important update on the current state of research on the aging auditory system. This update includes not only the recent research, but also consideration of how human and animal studies or translational and basic research are working in tandem to advance the field. This new edition is a natural complement to the previous SHAR volume on the aging auditory system edited by Gordon-Salant, Frisina, Popper, and Fay. The target audience for this volume will be graduate students, researchers, and academic faculty from a range of disciplines (psychology, hearing science/audiology, physiology, neuroscience, engineering). It also will appeal to clinical audiologists as well as to researchers working in the hearing device industry. Individuals who attend conferences sponsored by the Association for Research in Otolaryngology, Acoustical Society of America, Auditory Cognitive Neuroscience Society, American Auditory Society, Society for Neuroscience, American Speech, Language and Hearing Association, and the American Academy of Audiology (among others) are likely to find value in the volume.

The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just eight months. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are profound, and has required extreme social distancing measures across the globe in order to prevent overwhelming the healthcare services and hospitals. COVID-19 appears to have the greatest effects on elderly individuals and those who have co-morbid diseases, such as heart disease, asthma, and diabetes. As the peak begins to slow in many countries, the death rates remain high amidst justified fears of a second wave. A rapid worldwide mobilization has begun to identify effective treatments and develop vaccines. This new volume will increase readers' understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns. Leading experts will discuss the effects of the virus in cases of co-morbidities, new treatment approaches, mental health aspects of the pandemic, and convey the results of survey studies. The book will be an excellent resource for researchers studying virology, metabolic diseases, respiratory disorders, and clinical scientists, physicians, drug companies, and healthcare services and workers.

This book provides an up-to-date review and analysis of the carrot's nuclear and organellar genome structure and evolution. In addition, it highlights applications of carrot genomic information to elucidate the carrot's natural and agricultural history, reproductive biology, and the genetic basis of traits important in agriculture and human health. The carrot genome was sequenced in 2016, and its relatively small diploid genome, combined with the fact that it is the most complete root crop genome released to date and the first-ever Euasterid II genome to be sequenced, mean the carrot has an important role in the study of plant development and evolution. In addition, the carrot is among the top ten vegetables grown worldwide, and the abundant orange provitamin A carotenoids that account for its familiar orange color make it the richest crop source of vitamin A in the US diet, and in much of the world. This book includes the latest genetic maps, genetic tools and resources, and covers advances in genetic engineering that are relevant for plant breeders and biologists alike.

The principal objective of this book is to provide information needed to define human thermal behavior quantitatively. Human thermal physiology is defined using mathematical methods routinely employed by physicists and engineers, but seldom used by physiologists. Major sections of the book are devoted to blood flow, sweating, shivering, heat transfer within the body, and heat and mass transfer from skin and clothing to the environment. Simple algebraic models based on experimental data from a century of physiological investigation are developed for bodily processes. The book offers an invaluable source of information for physiologists and physical scientists interested in quantitative approaches to the fascinating field of human thermoregulation.

Microbes are ubiquitous in nature. Among microbes, fungal communities play an important role in agriculture, the environment, and medicine. Vast fungal diversity has been associated with plant systems, namely epiphytic fungi, endophytic fungi, and rhizospheric fungi. These fungi associated with plant systems play an important role in plant growth, crop yield, and soil health. Rhizospheric fungi, present in rhizospheric zones, get their nutrients from root exudates released by plant root systems, which help with their growth, development, and microbe activity. Endophytic fungi typically enter plant hosts through naturally occurring wounds that are the result of plant growth, through root hairs, or at epidermal conjunctions. Phyllospheric fungi may survive or proliferate on leaves depending on material influences in leaf diffuseness or exudates. The diverse nature of these fungal communities is a key component of soil-plant systems, where they are engaged in a network of interactions endophytically, phyllospherically, as well as in the rhizosphere, and thus have emerged as a promising tool for sustainable agriculture. These fungal communities promote plant growth directly and indirectly by using plant growth promoting (PGP) attributes. These PGP fungi can be used as biofertilizers and biocontrol agents in place of chemical fertilizers and pesticides for a more eco-friendly method of promoting sustainable agriculture and environments. This first volume of a two-volume set covers the biodiversity of plant-associated fungal communities and their role in plant growth promotion, the mitigation of abiotic stress, and soil fertility for sustainable agriculture. This book should be useful to those working in the biological sciences, especially for microbiologists, microbial biotechnologists, biochemists, and researchers and scientists of fungal biotechnology.

This book commemorates the scientific contributions of distinguished statistician, Andrei Yakovlev. It reflects upon Dr. Yakovlev's many research interests including stochastic modeling and the analysis of micro-array data, and throughout the book it emphasizes applications of the theory in biology, medicine and public health. The contributions to this volume are divided into two parts. Part A consists of original research articles, which can be roughly grouped into four thematic areas: (i) branching processes, especially as models for cell kinetics, (ii) multiple testing issues as they arise in the analysis of biologic data, (iii) applications of mathematical models and of new inferential techniques in epidemiology, and (iv) contributions to statistical methodology, with an emphasis on the modeling and analysis of survival time data. Part B consists of methodological research reported as a short communication, ending with some personal reflections on research fields associated with Andrei and on his approach to science. The Appendix contains an abbreviated vitae and a list of Andrei's publications, complete as far as we know. The contributions in this book are written by Dr. Yakovlev's collaborators and notable statisticians including former presidents of the Institute of Mathematical Statistics and of the Statistics Section of the AAAS. Dr. Yakovlev's research appeared in four books and almost 200 scientific papers, in mathematics, statistics, biomathematics and biology journals. Ultimately this book offers a tribute to Dr. Yakovlev's work and recognizes the legacy of his contributions in the biostatistics community.

Advances in Energy, Environment and Chemical Engineering collects papers resulting from the conference on Energy, Environment and Chemical Engineering (AEECE 2022), Dali, China, 24-26 June, 2022. The primary goal is to promote research and developmental activities in energy technology, environment engineering and chemical engineering. Moreover, it aims to promote scientific information interchange between scholars from the top universities, business associations, research centers and high-tech enterprises working all around the world. The conference conducts in-depth exchanges and discussions on relevant topics such as energy engineering, environment technology and advanced chemical technology, aiming to provide an academic and technical communication platform for scholars and engineers engaged in scientific research and engineering practice in the field of saving technologies, environmental chemistry, clean production and so on. By sharing the research status of scientific research achievements and cutting-edge technologies, it helps scholars and engineers all over the world comprehend the academic development trend and broaden research ideas. So as to strengthen international academic research, academic topics exchange and discussion, and promote the industrialization cooperation of academic achievements.