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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues

Stem Cells in Veterinary Science (Hardcover, 1st ed. 2021): Ratan Kumar Choudhary, Shanti Choudhary Stem Cells in Veterinary Science (Hardcover, 1st ed. 2021)
Ratan Kumar Choudhary, Shanti Choudhary
R5,077 Discovery Miles 50 770 Ships in 12 - 17 working days

This book explores the potential applications of animal stem cells in veterinary medicine. It begins with an overview of stem cells and their application in treating various animal diseases, including mastitis. In turn, the book discusses the challenges of using stem cells in regenerative medicine and emphasizes the importance of understanding the action of stem cells and preclinical evidence for ensuring safety and therapeutic efficacy. It also presents methods for the identification, characterization, and quantification of stem cells. Further, it discusses the therapeutic applications of different stem cells, including milk-derived, testicular, and mesenchymal stem cells in veterinary medicine. Lastly, it discusses strategies for and therapeutic applications of genome editing by CRISPER/Cas9 in mammary stem cells. As such, the book offers a valuable resource for students and scientists working in the veterinary sciences and veterinarians.

Advances in Agronomy, Volume 138 (Hardcover): Donald L. Sparks Advances in Agronomy, Volume 138 (Hardcover)
Donald L. Sparks
R5,316 Discovery Miles 53 160 Ships in 12 - 17 working days

Advances in Agronomy continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

Neuroepidemiology, Volume 138 (Hardcover): Caterina Rosano, M. Arfan Ikram, Mary Ganguli Neuroepidemiology, Volume 138 (Hardcover)
Caterina Rosano, M. Arfan Ikram, Mary Ganguli
R7,568 Discovery Miles 75 680 Ships in 12 - 17 working days

Neuroepidemiology covers the foundations of neuroepidemiological research and the epidemiology of disorders primarily affecting the nervous system, as well as those originating outside the nervous system. The etiology of many important central nervous system disorders remains elusive. Even with diseases where the key risk determinants have been identified, better prevention and therapy is needed to reduce high incidence and mortality. Although evolving technologies for studying disease provide opportunities for such, it is essential for researchers and clinicians to understand how best to apply such technology in the context of carefully characterized patient populations. By paying special attention to methodological approaches, this volume prepares new investigators from a variety of disciplines to conduct epidemiological studies in order to discern the etiologic factors and underlying mechanisms that influence the onset, progression, and recurrence of CNS disorders and diseases. The book also provides current information on methodological approaches for clinical neurologists seeking to expand their knowledge in research.

The Mind Within the Brain - How We Make Decisions and How those Decisions Go Wrong (Hardcover): A. David Redish The Mind Within the Brain - How We Make Decisions and How those Decisions Go Wrong (Hardcover)
A. David Redish
R1,221 Discovery Miles 12 210 Ships in 12 - 17 working days

In The Mind within the Brain, David Redish brings together cutting edge research in psychology, robotics, economics, neuroscience, and the new fields of neuroeconomics and computational psychiatry, to offer a unified theory of human decision-making. Most importantly, Redish shows how vulnerabilities, or "failure-modes," in the decision-making system can lead to serious dysfunctions, such as irrational behavior, addictions, problem gambling, and PTSD. Told with verve and humor in an easily readable style, Redish makes these difficult concepts understandable. Ranging widely from the surprising roles of emotion, habit, and narrative in decision-making, to the larger philosophical questions of how mind and brain are related, what makes us human, the nature of morality, free will, and the conundrum of robotics and consciousness, The Mind within the Brain offers fresh insight into one of the most complex aspects of human behavior.

The Oxford Handbook of Metamemory (Hardcover): John Dunlosky, Sarah Tauber The Oxford Handbook of Metamemory (Hardcover)
John Dunlosky, Sarah Tauber
R5,731 Discovery Miles 57 310 Ships in 12 - 17 working days

The Oxford Handbook of Metamemory investigates the human ability to evaluate and control learning and information retrieval processes. Each chapter in this authoritative guide highlights a different facet of metamemory research, including classical metamemory judgments; applications of metamemory research to the classroom and courtroom; and cutting-edge perspectives on continuing debates and theory. Chapters also provide broad historical overviews of each research area and discussions of promising directions for future research. The breadth and depth of coverage on offer in this Handbook make it ideal for seminars on metamemory or metacognition. It would also be a valuable supplement for advanced courses on cognitive psychology, of use especially to graduate students and more seasoned researchers who are interested in exploring metamemory for the first time.

Lectins - Innate immune defense and Therapeutics (Hardcover, 1st ed. 2021): Preetham Elumalai, Sreeja Lakshmi Lectins - Innate immune defense and Therapeutics (Hardcover, 1st ed. 2021)
Preetham Elumalai, Sreeja Lakshmi
R6,057 Discovery Miles 60 570 Ships in 12 - 17 working days

This book reviews the relationship between receptors, carbohydrate moieties, and pathogenic surfaces and lectins' pathophysiology of immune responses and examines the mechanisms of action of the molecules for the treatment potentials. Increasing evidence has suggested that lectin-carbohydrate interactions perform important roles in various regulations of immune responses, but much remains to be learned about these crucial properties and their interplay with other molecules. In addition, a better understanding of the structural and functional properties of lectin and the activated immune response will be of critical importance for the development of new diagnostic tools and therapeutic strategies. These key areas are the focus of this book, which documents the latest research findings in the field. Evidence is provided for the various lectin types from animal and plant as well as microbial or marine lectins, and this wide range of molecular knowledge directs us to various diseases, including infectious diseases and cancer. In presenting state-of-the-art knowledge on the interactions between lectin and its interactions,the book will help to pave the way for the development of novel targets for the prevention and treatment of many disorders.

Bootstrap Methods - With Applications in R (Hardcover, 1st ed. 2021): Gerhard Dikta, Marsel Scheer Bootstrap Methods - With Applications in R (Hardcover, 1st ed. 2021)
Gerhard Dikta, Marsel Scheer
R3,088 Discovery Miles 30 880 Ships in 12 - 17 working days

This book provides a compact introduction to the bootstrap method. In addition to classical results on point estimation and test theory, multivariate linear regression models and generalized linear models are covered in detail. Special attention is given to the use of bootstrap procedures to perform goodness-of-fit tests to validate model or distributional assumptions. In some cases, new methods are presented here for the first time. The text is motivated by practical examples and the implementations of the corresponding algorithms are always given directly in R in a comprehensible form. Overall, R is given great importance throughout. Each chapter includes a section of exercises and, for the more mathematically inclined readers, concludes with rigorous proofs. The intended audience is graduate students who already have a prior knowledge of probability theory and mathematical statistics.

The CRF Signal - Uncovering an Information Molecule (Hardcover): Jay Schulkin The CRF Signal - Uncovering an Information Molecule (Hardcover)
Jay Schulkin
R1,966 Discovery Miles 19 660 Ships in 12 - 17 working days

Information molecules, such as Cortico-Releasing Factor (CRF), are ancient and widely distributed across diverse organs, playing various regulatory roles. CRF has been associated with a range of human conditions, including fear and anxiety, social contact, and most recently, addiction - in particular the euphoric feelings associated with alcohol consumption. Since its original discovery, research has unearthed that the role of this molecule is much broader than first thought. The scientific community now knows that CRF is a dynamic and diversely widespread peptide hormone that plays many roles and has many functions, in addition to its role as a releasing factor in the brain. This book explores the role of CRF, examining the relationship between location and function. It considers recurrent features that are linked to CRF - movement and change. CRF expression in regions of the brain is tied to paying attention to novel events and invoking movement in response to those events. Indeed, CRF provokes simple organized rhythmic behavior and can be mobilized under diverse conditions, including adversity. Examining the evolutionary origins of CRH, its neural functions, and its role in a variety of human characteristics and social behaviors, this book provides unique insights into CRF, and will be of interest to students and researchers in Neuroscience, Psychology, and Biology.

Non-Coding RNAs and Epigenetic Regulation of Gene - Expression: Drivers of Natural Selection (Hardcover, New): Kevin V. Morris Non-Coding RNAs and Epigenetic Regulation of Gene - Expression: Drivers of Natural Selection (Hardcover, New)
Kevin V. Morris
R5,675 Discovery Miles 56 750 Ships in 10 - 15 working days

Non-coding RNAs potentially play an active role in modulating gene transcription and epigenetic states. Several genes in differentiated cells may be under some form of RNA based transcriptional and epigenetic regulatory control. This form of regulation may be controlled by selective pressures and influence the adaptability of the cell. The concept that RNA can control epigenetic states impacts on our understanding of the basic fabric of the cell and may have therapeutic potential. Many studies have been carried out on the modulation of gene transcription by non-coding RNAs. This book, written by a group of distinguished scientists under the expert guidance of the editor Kevin V. Morris, represents an important overview and summary of the field to date. The thirteen chapters are organized into three sections: Non-coding RNAs: Form, Function and Diversity; Non-coding RNAs: Gene Regulation and Epigenetics; and Non-coding RNAs: Disease and Therapeutics. This up-to-date volume is an essenti

Functional Neuroimaging in Exercise and Sport Sciences (Hardcover, 2012 ed.): Henning Boecker, Charles H. Hillman, Lukas... Functional Neuroimaging in Exercise and Sport Sciences (Hardcover, 2012 ed.)
Henning Boecker, Charles H. Hillman, Lukas Scheef, Heiko K. Struder
R7,399 Discovery Miles 73 990 Ships in 12 - 17 working days

Regular physical exercise is associated with substantial health benefits. Recent evidence not only holds for cardiovascular effects promoting "physical health," but also for the central nervous system believed to promote "brain health." Moderate physical exercise has been found to improve learning, memory, and attentional processing, with recent research indicating that neuroprotective mechanisms and associated plasticity in brain structure and function also benefit. Physical exercise is also known to induce a range of acute or sustained psychophysiological effects, among these mood elevation, stress reduction, anxiolysis, and hypoalgesia. Today, modern functional neuroimaging techniques afford direct measurement of the acute and chronic relation of physical exercise on the human brain, as well as the correlation of the derived physiological in vivo signals with behavioral outcomes recorded during and after exercise. A wide range of imaging techniques have been applied to human exercise research, ranging from electroencephalography (EEG), magnetoencephalography (MEG), near infrared spectroscopy (NIRS), magnetic resonance imaging (MRI) to positron emission tomography (PET). All of these imaging methods provide distinct information, and they differ considerably in terms of spatial and temporal resolution, availability, cost, and associated risks. However, from a "multimodal imaging" perspective, neuroimaging provides an unprecedented potential to unravel the neurobiology of human exercise, covering a wide spectrum ranging from structural plasticity in gray and white matter, network dynamics, global and regional perfusion, evoked neuronal responses to the quantification of neurotransmitter release. The aim of this book is to provide the current state of the human neuroimaging literature in the emerging field of the neurobiological exercise sciences and to outline future applications and directions of research.

Subtract - The Untapped Science of Less (Paperback): Leidy Klotz Subtract - The Untapped Science of Less (Paperback)
Leidy Klotz
R491 R419 Discovery Miles 4 190 Save R72 (15%) Ships in 10 - 15 working days
The Evolution of Faith - Christ, Science, and World Religions (Hardcover): Thomas R McFaul, Al Brunsting The Evolution of Faith - Christ, Science, and World Religions (Hardcover)
Thomas R McFaul, Al Brunsting
R1,099 R928 Discovery Miles 9 280 Save R171 (16%) Ships in 10 - 15 working days
Handbook of Thermoset-Based Biocomposites, Three-Volume Set (Hardcover): Chandrasekar Muthukumar, Senthil Muthu Kumar... Handbook of Thermoset-Based Biocomposites, Three-Volume Set (Hardcover)
Chandrasekar Muthukumar, Senthil Muthu Kumar Thiagamani, Senthilkumar Krishnasamy, Suchart Siengchin, Ahmad Ilyas Bin Rushdan
R12,416 Discovery Miles 124 160 Ships in 12 - 17 working days

Handbook of Thermoset-Based Biocomposites is a three-volume set that provides a comprehensive review on the recent developments, characterization, and applications of natural fiber-reinforced biocomposites. An in-depth look at hybrid composites, nanofillers, and natural fiber reinforcement is divided into three books on polyester, vinyl ester, and epoxy composites. The volumes explore the widespread applications of natural fiber-reinforced polyester, vinyl ester, and epoxy composites ranging from the aerospace sector, automotive parts, construction and building materials, sports equipment, and household appliances. Investigating the physio-chemical, mechanical, and thermal properties of these composites, the volumes also consider the influence of hybridization, fibre architecture, and fibre-ply orientation. This three-volume set serves as a useful reference for researchers, graduate students, and engineers in the field of composites.

Public Reason and Bioethics - Three Perspectives (Hardcover, 1st ed. 2021): Hon-lam Li, Michael Campbell Public Reason and Bioethics - Three Perspectives (Hardcover, 1st ed. 2021)
Hon-lam Li, Michael Campbell
R3,758 Discovery Miles 37 580 Ships in 12 - 17 working days

This book explores and elaborates three theories of public reason, drawn from Rawlsian political liberalism, natural law theory, and Confucianism. Drawing together academics from these separate approaches, the volume explores how the three theories critique each other, as well as how each one brings its theoretical arsenal to bear on the urgent contemporary debate of medical assistance in dying. The volume is structured in two parts: an exploration of the three traditions, followed by an in-depth overview of the conceptual and historical background. In Part I, the three comprehensive opening chapters are supplemented by six dynamic chapters in dialogue with each other, each author responding to the other two traditions, and subsequently reflecting on the possible deficiencies of their own theories. The chapters in Part II cover a broad range of subjects, from an overview of the history of bioethics to the nature of autonomy and its status as a moral and political value. In its entirety, the volume provides a vibrant and exemplary collaborative resource to scholars interested in the role of public reason and its relevance in bioethical debate.

The Evolution of Human Sociability - Desires, Fears, Sex and Society (Hardcover): Ron Vannelli The Evolution of Human Sociability - Desires, Fears, Sex and Society (Hardcover)
Ron Vannelli
R3,098 R2,774 Discovery Miles 27 740 Save R324 (10%) Ships in 12 - 17 working days

How do desires and fears motivate human sociability? What effect do these motivators have on reproductive, social and political behaviour? And, crucially, how might we understand them separate from preconceived notions of design or higher morality? Taking these questions as a focus, this book examines human evolution with the emphasis on sexual selection and the evolution of a number of human psychological processes. Exploring evolutionary, sexual and maturational processes, along with primate, fossil and geological evidence, Vannelli argues that human nature can be conceptualised as species-typical desires and fears, derived from sexual selection during human evolution, and that these are major motivators of behaviour. Presenting additional evidence from the anthropology of band societies, along with material from group behaviour, Vannelli highlights the importance of pair-bonding, friendship, alliance behaviour, vengeance seeking and interpersonal politics in social behaviour, providing a unique interdisciplinary framework for understanding human nature and the evolution of human sociability.

Alexander Disease - A Guide for Patients and Families (Hardcover): Albee Messing Alexander Disease - A Guide for Patients and Families (Hardcover)
Albee Messing; Series edited by Alexei Verkhratsky, Vladimir Parpura
R1,595 Discovery Miles 15 950 Ships in 10 - 15 working days

This book offers a comprehensive overview of Alexander disease, a rare and devastating neurological disorder that often affects the white matter of the brain and spinal cord. Its distinctive neuropathology consists of abundant Rosenthal fibers within astrocytes (one of the four major cell types of the central nervous system). Nearly all cases are caused by variants in the gene encoding the intermediate filament protein GFAP, but how these changes in GFAP lead to the widespread manifestations of disease is poorly understood. Astrocytes, while discovered over a century ago, are themselves still much of a mystery. They exhibit considerable diversity, defy precise definition, and yet actively regulate many aspects of nervous system functioning. We also have incomplete understanding of Rosenthal fibers, odd structures that contain GFAP as just one of many components. Whether they are toxic or protective is unknown. Moreover, Rosenthal fibers are not absolutely unique to Alexander disease, and are seen sporadically in a wide variety of other conditions, including brain tumors and multiple sclerosis. GFAP is the third unknown. It is an ancient protein, arising early in the evolution of vertebrates, but its role in normal biology is still a matter of debate. Yet Alexander disease shows, without a doubt, that changing just a single of its 432 amino acids can lead to catastrophe, not just in the astrocytes where GFAP is produced but also in the other cells with which astrocytes interact. Despite all of the unknowns, much has been learned in the past 20 years, and it is time to share this knowledge. This book is intended for recently diagnosed patients and families, as well as non-specialist researchers interested in this neurological disease. It covers historical origins, the state of current knowledge, and prospects for what lies ahead, with citations to the primary literature given throughout.

Performance Psychology - Perception, Action, Cognition, and Emotion (Hardcover): Markus Raab, Babett Lobinger, Sven Hoffmann,... Performance Psychology - Perception, Action, Cognition, and Emotion (Hardcover)
Markus Raab, Babett Lobinger, Sven Hoffmann, Alexandra Pizzera, Sylvain Laborde
R2,690 Discovery Miles 26 900 Ships in 12 - 17 working days

This book integrates findings from across domains in performance psychology to focus on core research on what influences peak and non-peak performance. The book explores basic and applied research identifying cognition-action interactions, perception-cognition interactions, emotion-cognition interactions, and perception-action interactions. The book explores performance in sports, music, and the arts both for individuals and teams/groups, looking at the influence of cognition, perception, personality, motivation and drive, attention, stress, coaching, and age. This comprehensive work includes contributions from the US, UK, Canada, Germany, and Australia.

Circadian Rhythms and Biological Clocks Part B, Volume 552 (Hardcover): Amita Sehgal Circadian Rhythms and Biological Clocks Part B, Volume 552 (Hardcover)
Amita Sehgal
R5,257 Discovery Miles 52 570 Ships in 12 - 17 working days

Two new volumes of Methods in Enzymology continue the legacy of this premier serial with quality chapters authored by leaders in the field. Circadian Rhythms and Biological Clocks Part A and Part B is an exceptional resource for anybody interested in the general area of circadian rhythms. As key elements of timekeeping are conserved in organisms across the phylogenetic tree, and our understanding of circadian biology has benefited tremendously from work done in many species, the volume provides a wide range of assays for different biological systems. Protocols are provided to assess clock function, entrainment of the clock to stimuli such as light and food, and output rhythms of behavior and physiology. This volume also delves into the impact of circadian disruption on human health. Contributions are from leaders in the field who have made major discoveries using the methods presented here.

Computational Biology (Hardcover): Daniel McGuire Computational Biology (Hardcover)
Daniel McGuire
R3,438 R3,109 Discovery Miles 31 090 Save R329 (10%) Ships in 10 - 15 working days
Drought Management and Desertification Control - Still Miles to Go (Hardcover): R P Dhir Drought Management and Desertification Control - Still Miles to Go (Hardcover)
R P Dhir
R1,846 Discovery Miles 18 460 Ships in 12 - 17 working days
Mechanism of the Anticancer Effect of Phytochemicals, Volume 37 (Hardcover): S Zahra Bathaie, Fuyuhiko Tamanoi Mechanism of the Anticancer Effect of Phytochemicals, Volume 37 (Hardcover)
S Zahra Bathaie, Fuyuhiko Tamanoi
R4,655 R4,202 Discovery Miles 42 020 Save R453 (10%) Ships in 12 - 17 working days

Volume 37 will provide details on the major chemical constituents of medicinal plants and their mechanism of action as the anticancer compounds. This special issue, in addition to the previous volume (volume 36 of The Enzyme series was on Natural Products and Cancer Signaling Targets: Isoprenoids, Polyphenols and Flavonoids), will highlight the significant advance made in the field in elucidating mechanisms of anticancer effect of the major phytochemicals.

Behavioral Neuroscience (Hardcover): Sara Palermo, Rosalba Morese Behavioral Neuroscience (Hardcover)
Sara Palermo, Rosalba Morese
R3,327 Discovery Miles 33 270 Ships in 10 - 15 working days
New Therapeutic Strategies for Brain Edema and Cell Injury, Volume 146 (Hardcover): Hari Shanker Sharma, Aruna Sharma New Therapeutic Strategies for Brain Edema and Cell Injury, Volume 146 (Hardcover)
Hari Shanker Sharma, Aruna Sharma
R5,501 Discovery Miles 55 010 Ships in 12 - 17 working days

New Therapeutic Strategies for Brain Edema and Cell Injury, Volume 145, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this volume presenting interesting chapters on the Blood-brain barrier breakdown and brain edema formation in Alzheimer’s disease, Blast brain Injury induced edema formation and therapeutic measures, Brain edema in Parkinson’s disease. Novel therapeutic strategies, Brain edema and blood-brain barrier breakdown in sleep deprivation. Therapeutic potential of cerebrolysin, Differential cell injury induced by NMDA antagonist MK 801 in early age, Anesthetics influence Brain edema in concussive head injury, and more.

Biocatalysts in Biomass to Bioproducts (Hardcover): K Etl Al Ramasamy Biocatalysts in Biomass to Bioproducts (Hardcover)
K Etl Al Ramasamy
R2,140 Discovery Miles 21 400 Ships in 12 - 17 working days
Power Of Your Subconscious Mind Hardcover (Hardcover): Joseph Murphy Power Of Your Subconscious Mind Hardcover (Hardcover)
Joseph Murphy
R714 R630 Discovery Miles 6 300 Save R84 (12%) Ships in 10 - 15 working days
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