Progress in Brain Research series highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Preparing a Workforce for the New Blue Economy: People, Products and Policies discusses the Blue Economy, how the industry will develop, and how to train the next generation. The book considers the use of big data, key skillsets, training undergraduate and graduate students, the Transition Assistance Program (TAP) in the US, economic opportunities in African coastal countries, and governmental agencies, non-profits and NGO's. Finally, a broad range of case studies are provided, covering oil spills, commercial fishing, data protection and harvesting, sustainability and weather forecasting, all presented to highlight the educational requirements of the workforce and potential economic opportunities.

Inoculating Cities: Case Studies of Urban Pandemic Preparedness begins with a brief historical description of infectious disease outbreaks in cities as well as an overview of infectious disease outbreaks since 2000 that hold profound implications for cities and urban environments - such as severe acute respiratory syndrome (SARS) in 2003, H1N1 influenza in 2009, Ebola virus in 2014, Zika virus in 2015, and more recently, COVID-19 in 2020. Each of these outbreaks affected different geographies of the world and underscored the importance of urban pandemic preparedness or urban health security as a means of mitigating the threats posed by infectious diseases. This book describes several of the characteristics of cities that make them uniquely vulnerable to infectious disease threats which include, but are not limited to, their population density, population diversity, internal and external population movements, and inequalities in cities. Finally, the book discusses frameworks and capacities that are essential for preparing cities to prevent, detect, and respond to infectious disease outbreaks. With contributions from experts and researchers with first-hand experiences with infectious disease outbreaks, their impact on the management of disease, and pandemic preparedness in progressively urban societies, Inoculating Cities addresses the unique threats infectious diseases pose to urban environments and surveys innovative models that cities are using to combat these threats.

Stress Tolerance in Horticultural Crops: Challenges and Mitigation Strategies explores concepts, strategies and recent advancements in the area of abiotic stress tolerance in horticultural crops, highlighting the latest advances in molecular breeding, genome sequencing and functional genomics approaches. Further sections present specific insights on different aspects of abiotic stress tolerance from classical breeding, hybrid breeding, speed breeding, epigenetics, gene/quantitative trait loci (QTL) mapping, transgenics, physiological and biochemical approaches to OMICS approaches, including functional genomics, proteomics and genomics assisted breeding. Due to constantly changing environmental conditions, abiotic stress such as high temperature, salinity and drought are being understood as an imminent threat to horticultural crops, including their detrimental effects on plant growth, development, reproduction, and ultimately, on yield. This book offers a comprehensive resource on new developments that is ideal for anyone working in the field of abiotic stress management in horticultural crops, including researchers, students and educators.

Translational Bioinformatics in Healthcare and Medicine offers an overview of main principles of bioinformatics, biological databases, clinical informatics, health informatics, viroinformatics and real-case applications of translational bioinformatics in healthcare. Written by experts from both technology and clinical sides, the content brings together essential knowledge to make the best of recent advancements of the field. The book discusses topics such as next generation sequence analysis, genomics in clinical care, IoT applications, blockchain technology, patient centered interoperability of EHR, health data mining, and translational bioinformatics methods for drug discovery and drug repurposing. In addition, it discusses the role of bioinformatics in cancer research and viroinformatics approaches to counter viral diseases through informatics. This is a valuable resource for bioinformaticians, clinicians, healthcare professionals, graduate students and several members of biomedical field who are interested in learning more about how bioinformatics can impact in their research and practice.

According to the World Health Organization, schizophrenia affects more than 21 million people worldwide, causing distortions in thinking, perception, emotions, language, sense of self, behavior, and hallucinations. Cognitive and Behavioral Dysfunction in Schizophrenia provides an overview of topics and theories related to cognitive dysfunction in schizophrenia. This book discusses what schizophrenia is and its relationship with the cognitive domains including, but not limited to, learning, working memory, attention, and both deductive and inductive reasoning. This book also reviews theories as to why some individuals develop schizophrenia following cannabis and amphetamine abuse and how these relate to additional cognitive problems. The book further discusses recent topics related to religious delusions in psychotic patients, impact of sleep on psychosis, how urban life increases the likelihood of developing schizophrenia, as well as sexual dysfunction in schizophrenia patients. Unlike other books, Cognitive and Behavioral Dysfunction in Schizophrenia covers many cognitive domains related to the occurrence and development of positive and negative symptoms of schizophrenia. Advanced students and researchers in cognitive and behavioral neuroscience, psychology, psychiatry, and psychotherapy will find it useful for a well-rounded understanding of the subject.

Advances in Agronomy, Volume 167, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field. Each chapter is written by an international board of authors.

Tinnitus - An Interdisciplinary Approach Towards Individualized Treatment: Towards Understanding the Complexity of Tinnitus, Volume 262, the latest release in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on current topics such as Cochlear implantation for patients with tinnitus - a systematic review, Event Related Potentials to Assess the Tinnitus complaint during drug treatment, The difference in post-stimulus suppression between residual inhibition and forward masking, Sleep, sleep apnea and tinnitus, A Bayesian brain in imbalance: medial, lateral and descending pathways in tinnitus and pain, Tinnitus features according to caffeine consumption, and much more.

The volume discusses novel issues associated with the neurotoxicity of select metals

Novel Approaches to Colorectal Cancer, Volume 151 in the Advances in Cancer Research series, is composed of 11 reviews covering state-of-the-art research relating to the etiology, diagnosis, prevention and treatment of colorectal cancer. The book's chapters were written by recognized experts in the field, and include sections on molecular biomarkers in diagnosis and therapy, the interplay of diet, lifestyle, and the microbiome, early-age onset disease, mutational signature analysis, challenges in early detection, immunotherapy, organoid technology, the role of epigenetic alterations, disparities in minority populations, field carcinogenesis, and cancer as an evolutionary process. Each of these topics provides novel insights and concepts on various aspects of the nature of colorectal cancer, offering new opportunities for the management of a major source of cancer incidence and mortality.

Fundamentals of Tropical Freshwater Wetlands: From Ecology to Conservation Management is a practical guide and important tool for practitioners and educators interested in the ecology, conservation and management of wetlands in tropical/subtropical regions. The book is written in such a way that, in addition to scientists and managers, it is accessible to non-specialist readers. Organized into three themed sections and twenty-three chapters, this volume covers a variety of topics, exposing the reader to a full range of scientific, conservation and management issues. Each chapter has been written by specialists in the topic being presented. The book recognizes that wetland conservation, science and management are interlinked disciplines, and so it attempts to combine several perspectives to highlight the interdependence between the various professions that deal with issues in these environments. Within each chapter extensive cross-referencing is included, so as to help the reader link related aspects of the issues being discussed.

Advances in Cancer Research, Volume 150, the latest release in this ongoing series, covers the relationship(s) between autophagy and senescence, how they are defined, and the influence of these cellular responses on tumor dormancy and disease recurrence. Specific sections in this new release include Autophagy and senescence, converging roles in pathophysiology, Cellular senescence and tumor promotion: role of the unfolded protein response, autophagy and senescence in cancer stem cells, Targeting the stress support network regulated by autophagy and senescence for cancer treatment, Autophagy and PTEN in DNA damage-induced senescence, mTOR as a senescence manipulation target: A forked road, and more.

Nearly 44 million people have Alzheimer's or related dementia worldwide, according to the Alzheimer's Disease International organization. That number is expected to double every 20 years. Unlike other books on the market, Alzheimer's Disease: Understanding Biomarkers, Big Data, and Therapy covers recent advancements in cognitive, clinical, neural, and therapeutic aspects of Alzheimer's and other forms of dementia. First, readers are introduced to cognitive and clinical studies, focusing on the different types of memory impairment, past and future thinking. This includes the prevalence of depression, its relationship to other symptoms, and the quality of life for those with Alzheimer's disease. In addition, the book discusses recent studies on memory dysfunction in advanced-stage Alzheimer's disease, in comparison to early-stage, including a chapter on the underlying factors in the transition from mild cognitive impairment to Alzheimer's diagnosis. Following this section, the book presents recent studies on the role of different cortical and subcortical structures in the development of various symptoms in Alzheimer's disease, as well as different neural biomarkers underlying the development and treatment of the disease. In the last section of the book, therapeutic aspects of Alzheimer's disease, focusing on behavioral and pharmacological treatments of sleep disorders, memory problems, and depression, are reviewed. The book aids readers in understanding the advances in research and care, making it a prime tool for all clinicians, psychologists, researchers, neurologists, and caregivers of dementia patients.

Prenatal Genetic Counseling: Practical Support for Prenatal Diagnostics, Decision-Making, and Dealing with Uncertainty provides a foundation for new research and a one-stop source for physicians, genetic counselors, psychologists, social workers, general practitioners, grief workers, translational researchers, and administrators seeking to work in the field of clinical genomics ethically and in full consideration of patients' psychological well-being. Here, an international team of experienced counselors and clinician-scientists lay out the range of methods and technologies applied in prenatal decision-making, including NIPT; invasive testing with microarray analysis or whole genome sequencing; ultrasound screening; and prenatal diagnosis for known hereditary conditions, among others. From here, they examine specific challenges in the clinical translation. In a field where decisions about life or death of a child are made, professionals are bound to encounter uncertainty. This book was co-created by health care practitioners, scientists, patients and students to provide insights and direction for offering support straight from the heart to couples faced with fetal anomalies. To make this possible for all couples, diversity in prenatal genetic counseling is also addressed. Finally, next steps in prenatal genetic counseling research and clinical implementation are discussed. As we are challenged by the rapid advances in prenatal genomics, so are our patients. Learning from our patients with every encounter, this book aims to offer access to the insights we gathered as well as to stimulate lifelong learning.

Handbook of Gastrointestinal Motility and Disorders of Gut and Brain Interactions, Second Edition fills the void in GI literature for a short and concise go-to book for GI motility and gut and brain interactions disorders. This exceptionally illustrated reference contains all the information needed for a quick reference of GI motility and disorders of the gut and brain interactions, as well as adolescent and pediatric disorders and disorders which affect the entire GI system, each systematically arranged by disorder and gut anatomy for easy reference. Each chapter also includes extensive color pictures and illustrations of each test involved as well as descriptions of how to perform and interpret the motility tests that are incorporated into patient care decisions. The current advances in the field have led the way for new updates to existing content as well as a new section for the book dedicated to systemic disorders and special topics including neurology of the gut, cannabis and the gut, eating disorders, pediatric and adolescent disorders, nutritional therapies, and psychological evaluation and treatment. This is the perfect reference for those who encounter the common problems of dysphagia, heartburn, nausea, vomiting, abdominal pain, irritable bowel syndrome, constipation, and fecal incontinence in daily practice including practicing physicians, gastroenterologists, motility laboratory personnel, surgeons, and internists.

Stem Cells and Aging covers what is known about the effect of time and age on the basic units of life, which are the corresponding tissue-specific or adult stem cells. Even though the concept of stem cells was introduced nearly a century ago by Alexander Maximow, modern stem-cell research began in 1963 when James Till, Ernest McCullough and Lou Siminovitch established assays to detect hematopoietic stem cells. In fact, given the importance of the aging-associated diseases, scientists have developed a keen interest in understanding the aging process as they attempt to define the role of dysfunctional stem cells in the aging process. With an aging population worldwide, understanding these age-related stem cell changes at a basic biology level and at the level of their influences for regenerative medicine is of interest and importance. There is increasing evidence that the aging process can have much adverse effects on stem cells. In the modern era, one of the emerging fields in treating human diseases is stem cell research, as stem cells have the remarkable potential to treat a wide range of diseases. Nevertheless, understanding the molecular mechanism involved in aging and deterioration of stem cell function is crucial in developing effective new therapies for aging.

Tinnitus - An Interdisciplinary Approach Towards Individualized Treatment, Volume 261, the latest release in the Neuropharmacology of Neuroprotection series, presents the latest research on the topic of Progress in Brain Research. This series highlights new advances in the field, providing comprehensive and timely chapters written by an international board of esteemed authors.

Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim's appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies.

The Beans and the Peas: From Orphan to Mainstream Crops presents a comprehensive literature resource on the most important food legume crops previously known as "orphans," but which are increasingly becoming mainstream as their production opportunities have been improved through genetic improvement and biotechnology, and their role as an important nutrient source gains urgency. This book focuses on 12 important food legumes and discusses all relevant aspects on their economic importance, crop statistics, botany, and their general description. It also provides exhaustive information on plant genetic resources and their use, genetic improvement, resistance to biotic and abiotic stresses, improved varieties, agronomy, seed system, and use of information and communication tools in each individual food legume. Development of innovative biotechnological tools, genetic transformation, and the genome sequencing information has also been covered in each chapter providing the readers with state-of-the-art information on pulses. All chapters have been supported by relevant figures, illustrations, and tables, which make the contents accessible and easy to understand. Each of the chapters has been authored by globally known scientists/researchers presenting up-to-date information on various aspects of food legumes. This book provides a current and comprehensive treatise to the readers and will be tremendously helpful in furthering their academic and research pursuits.

Pragmatic Randomized Clinical Trials Using Primary Data Collection and Electronic Health Records addresses the practical aspects and challenges of the design, implementation, and dissemination of pragmatic randomized trials, also sometimes referred to as practical or hybrid randomized trials. While less restrictive and more generalizable than traditional randomized controlled trials, such trials have specific challenges which are addressed in this book. The book contains chapters encompassing common designs along with advantages and limitations of such designs, analytic aspects in planning trials and estimating sample size, and how to use patient partners to help design and operationalize pragmatic randomized trials. Pragmatic trials conducted using primary data collection and trials embedded in electronic health records - including electronic medical records and administrative insurance claims - are addressed. This comprehensive resource is valuable not only for pharmacoepidemiologists, biostatisticians and clinical researchers, but also across the biomedical field for those who are interested in applying pragmatic randomized clinical trials in their research.

Written by leading experts in their respective fields, Principles and Applications of Soil Microbiology 3e, provides a comprehensive, balanced introduction to soil microbiology, and captures the rapid advances in the field such as recent discoveries regarding habitats and organisms, microbially mediated transformations, and applied environmental topics. Carefully edited for ease of reading, it aids users by providing an excellent multi-authored reference, the type of book that is continually used in the field. Background information is provided in the first part of the book for ease of comprehension. The following chapters then describe such fundamental topics as soil environment and microbial processes, microbial groups and their interactions, and thoroughly addresses critical nutrient cycles and important environmental and agricultural applications. An excellent textbook and desk reference, Principles and Applications of Soil Microbiology, 3e, provides readers with broad, foundational coverage of the vast array of microorganisms that live in soil and the major biogeochemical processes they control. Soil scientists, environmental scientists, and others, including soil health and conservation specialists, will find this material invaluable for understanding the amazingly diverse world of soil microbiology, managing agricultural and environmental systems, and formulating environmental policy.