Professor Steve Peters is a Consultant Psychiatrist and author of the bestselling self-help book, The Chimp Paradox. He has years of experience as a clinician, an educator and has worked with some of the world's most successful athletes. His new book 'A Path through the Jungle' will help you to become robust and resilient. Professor Peters explains complex neuroscience in straightforward terms with his Chimp Management Mind Model Robust: Becoming robust means having plans in place to manage your own mind and whatever situations you meet in life. Resilient: is being able to bounce back and manage the challenges of life. Resilience is a skill. A Path through the Jungle offers a structured programme with exercises and practical real-life examples. This book will help you to improve in areas such as: * Managing stress and anxiety * Improved relationships * Emotional management * Grief and loss * Self-confidence * Peace of mind * Happiness * Managing stress

Measuring metabolic rates is central to important questions in many areas of scientific research. Unfortunately these measurements are anything but straightforward, and numerous pitfalls await the novice and even the experienced investigator.
Measuring Metabolic Rates de-mystifies the field, explaining every common variation of metabolic rate measurement, from century-old manometric methods through ingenious syringe-based techniques, direct calorimetry, aquatic respirometry, stable-isotope metabolic measurement and every type of flow-through respirometry. Each variation is described in enough detail to allow it to be applied in practice. Background information on different analyzer and equipment types allows users to choose the best instruments for their application. Respirometry equations - normally a topic of terror and confusion to researchers - are derived and described in enough detail to make their selection and use effortless.
Vital topics such as manual and automated baselining, implementing multi-animal systems, and the correct analysis and presentation of metabolic data are covered in enough detail to turn a respirometry neophyte into a hardened metabolic warrior, ready to take on the task of publication in peer-reviewed journals.

The human pathogens Neisseria meningitidis and Neisseria gonorrhoeae are exquisitely adapted to life within the human mucosa, their only natural niche. N. meningitidis is the causative agent of rapidly transmissible meningitis and septic shock. Vaccines developed to control this pathogen can be rendered ineffective by the pathogen's ability to undergo antigenic variation. In contrast, there are no current vaccination prospects for N. gonorrhoeae, the causative agent of sexually transmitted gonorrhoea. Historically, infections caused by N. gonorrhoeae were treated with antibiotics. However, the recent advent of new strains with resistance to all known antibiotics is causing such treatment regimes to fail, necessitating the need for new and more effective control strategies. In this book, leading Neisseria authorities review the most important research on pathogenic Neisseria to provide a timely overview of the field. The topics covered include: the link between pathogenesis and important metabolic pathways * vaccine development * antibiotic resistance * transcriptomics of regulatory networks * regulatory small RNAs * interactions with neutrophils * advances in humanized mouse models. An essential guide for research scientists, advanced students, clinicians, and other professionals working with Neisseria, the book is a recommended text for all microbiology libraries.

Rapid advances in high-throughput genome sequencing technologies foreshadow a near-future in which millions of individuals will gain affordable access to their complete genome sequence. This promises to offer unprecedented insights into the fundamental biological nature of ourselves and our species: where we came from, how we begin our lives, how we develop and grow, how we interact with our environment, how we get sick, how we get well, and how we age. Personal genomics is an essential component of the inevitable transition towards personalized health and medicine. As the medical establishment begins to explore and evaluate the role of personal genomics in health and medicine, both clinicians and patients alike will gain from becoming well versed in both the power and the pitfalls of personal genomic information. Furthermore, it is likely that all students of the biomedical sciences will soon be required to gain crucial understanding in the emerging field of personal genomics. Exploring Personal Genomics provides a novel, inquiry-based approach to the understanding and interpretation of the practical, medical, physiological, and societal aspects of personal genomic information. The material is presented in two parts: the first provides readers of all backgrounds with a fundamental understanding of the biology of human genomes, information on how to obtain and understand digital representations of personal genomic data, tools and techniques for exploring the personal genomics of ancestry and genealogy, discovery and interpretation of genetic trait associations, and the role of personal genomics in drug response. The second part offers more advanced readers an understanding of the science, tools, and techniques for investigating interactions between a personal genome and the environment, connecting DNA to physiology, and assessing rare variants and structural variation. This book aims to support undergraduate and graduate studies in medicine, genetics, molecular biology, and bioinformatics. Additionally, the design of the content is such that medical practitioners, professionals working in the biomedical sciences or related fields, and motivated lay individuals interested in exploring their personal genetic data should find it relevant and approachable.

Observing Bioethics examines the history of bioethics as a discipline related not only to modern biology, medicine, and biotechnology, but also to the core values and beliefs of American society and its courts, legislatures, and media. The book is written from the perspective of two social scientists--a sociologist of medicine(Renee C. Fox) and a historian of medicine (Judith P. Swazey)--who have participated in bioethics since the emergence of this multidisciplinary field more than 30 years ago.
Fox and Swazey draw on first-hand observations and experiences in a variety of American bioethical settings; face-to-face interviews with first- and second-generation figures in the genesis and early unfolding of bioethics; a detailed examination of the theatrical media coverage of what was considered to be a banner event in the annals of bioethics (the creation and birth of the cloned sheep, Dolly); case studies of how bioethics has internationally developed; and a large corpus of primary documents and secondary source materials.
While recognizing the intellectual, moral, and sociological importance of American bioethics, Fox and Swazey are critical of its characteristics. Foremost among these are what they identify as the problems of thinking socially, culturally, and internationally in American bioethics; the 'tenuous interdisciplinarity' of the field; and the troubling extent to which the 'culture wars' have penetrated bioethics.
This book will appeal to a wide range of doctors, scientists, and academics who are involved in the history and sociology of bioethics.

For modern scientists, history often starts with last week's journals and is regarded as largely a quaint interest compared with the advances of today. However, this book makes the case that, measured by major advances, the greatest decade in the history of brain studies was mid-twentieth century, especially the 1950s. The first to focus on worldwide contributions in this period, the book ranges through dozens of astonishing discoveries at all levels of the brain, from DNA (Watson and Crick), through growth factors (Hamburger and Levi-Montalcini), excitability (Hodgkin and Huxley), synapses (Katz and Eccles), dopamine and Parkinson's (Carlsson), visual processing (Hartline and Kuffler), the cortical column (Mountcastle), reticular activating system (Morruzzi and Magoun) and REM sleep (Aserinsky), to stress (Selye), learning (Hebb) and memory (HM and Milner). The clinical fields are also covered, from Cushing and Penfield, psychosurgery and brain energy metabolism (Kety), to most of the major psychoactive drugs in use today (beginning with Delay and Deniker), and much more.
The material has been the basis for a highly successful advanced undergraduate and graduate course at Yale, with the classic papers organized and accessible on the web. There is interest for a wide range of readers, academic, and lay because there is a focus on the creative process itself, on understanding how the combination of unique personalities, innovative hypotheses, and new methods led to the advances. Insight is given into this process through describing the struggles between male and female, student and mentor, academic and private sector, and the roles of chance and persistence. The book thus provides a new multidisciplinary understanding of the revolution that created the modern field of neuroscience and set the bar for judging current and future advances.

This book is about pleasure. It's also about pain. Most important, it's about how to find the delicate balance between the two, and why now more than ever finding balance is essential.

We're living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting... The increased numbers, variety, and potency is staggering. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation. As such we've all become vulnerable to compulsive overconsumption.

In Dopamine Nation, Dr. Anna Lembke, psychiatrist and author, explores the exciting new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain...and what to do about it. Condensing complex neuroscience into easy-to-understand metaphors, Lembke illustrates how finding contentment and connectedness means keeping dopamine in check. The lived experiences of her patients are the gripping fabric of her narrative. Their riveting stories of suffering and redemption give us all hope for managing our consumption and transforming our lives. In essence, Dopamine Nation shows that the secret to finding balance is combining the science of desire with the wisdom of recovery.

The Arctic Tundra and adjacent Boreal Forest or Taiga support the most cold-adapted flora and fauna on Earth. The evolutionary capacity of both plants and animals to adapt to these thermally limiting conditions has always attracted biological investigation and is a central theme of this book. How the polar biota will adapt to a warmer world is creating significant and renewed interest in this habitat. The Arctic has always been subject to climatic fluctuation and the polar biota has successfully adapted to these changes throughout its evolutionary history. Whether or not climatic warming will allow the Boreal Forest to advance onto the treeless Tundra is one of the most tantalizing questions that can be asked today in relation to terrestrial polar biology. Tundra-Taiga Biology provides a circum-polar perspective of adaptation to low temperatures and short growing seasons, together with a history of climatic variation as it has affected the evolution of terrestrial life in the Tundra and the adjacent forested Taiga. It will appeal to researchers new to the field and to the many students, professional ecologists and conservation practitioners requiring a concise but authoritative overview of the biome. Its accessibility also makes it suitable for undergraduate and graduate students taking courses in tundra, taiga, and arctic ecology.

Because of their vital role in the emergence of humanity, tools and their uses have been the focus of considerable worldwide study. This volume brings together international research on the use of tools among primates and both prehistoric and modern humans. The book represents leading work being done by specialists in anatomy, neurobiology, prehistory, ethnology, and primatology. Whether composed of stone, wood, or metal, tools are a prolongation of the arm that acquire precision through direction by the brain. The same movement, for example, may have been practiced by apes and humans, but the resulting action varies according to the extended use of the tool. It is therefore necessary, as the contributors here make clear, to understand the origin of tools, and also to describe the techniques involved in their manipulation, and the possible uses of unknown implements. Comparison of the techniques of chimpanzees with those of prehistoric and modern peoples has made it possible to appreciate the common aspects and to identify the differences. The transmission of ability has also been studied in the various relevant societies: chimpanzees in their natural habitat and in captivity, hunter-gatherers, and workmen in prehistoric and in modern times. In drawing together much valuable research, this work will be an important and timely resource for social and behavioral psychologists, anthropologists, paleontologists, and animal behaviorists.

This volume presents state-of-the-art empirical studies working in a paradigm that has become known as human behavioral ecology. The emergence of this approach in anthropology was marked by publication by Aldine in 1979 of an earlier collection of studies edited by Chagnon and Irons entitled Evolutionary Biology and Human Social Behavior: An Anthropological Perspective. During the two decades that have passed since then, this innovative approach has matured and expanded into new areas that are explored here.

The book opens with an introductory chapter by Chagnon and Irons tracing the origins of human behavioral ecology and its subsequent development. Subsequent chapters, written by both younger scholars and established researchers, cover a wide range of societies and topics organ-ized into six sections. The first section includes two chapters that provide historical background on the development of human behavioral ecology and com-pare it to two complementary approaches in the study of evolution and human behavior, evolutionary psychology, and dual inheritance theory. The second section includes five studies of mating efforts in a variety of societies from South America and Africa. The third section covers parenting, with five studies on soci-eties from Africa, Asia, and North America. The fourth section breaks somewhat with the tradition in human behavioral ecology by focusing on one particularly problematic issue, the demographic transition, using data from Europe, North America, and Asia. The fifth section includes studies of cooperation and helping behaviors, using data from societies in Micronesia and South America. The sixth and final section consists of a single chapter that places the volume in a broader critical and comparative context.

The contributions to this volume demonstrate, with a high degree of theoretical and methodological sophistication--the maturity and freshness of this new paradigm in the study of human behavior. The volume will be of interest to anthropologists and other professions working on the study of cross-cultural human behavior.

Flora of North America, Volume 3, provides information on many of the most familiar wildflowers and trees in North America. Included are treatments of the buttercup family (Ranunculacaeae), with such plants as delphiniums and columbines, and the poppy family (Papveraceae). Most of the important broadleaf tree species are covered, including the oaks (Fagaceae), elms (Ulmaceae), birches (Betulaceae), walnuts (Juglandaceae), plane trees (Plantanaceae), and magnolias (Magnoliaceae). Many striking families are covered, such as the dutchman's pipe family (Aristochiaceae), and the aquatic families Nymphaeceae (water lilies), and Melumbonaceae (lotus).

Identification keys, summaries of habitats and geographic ranges, distribution maps, pertinent synonymies, descriptions, chromosome numbers, phenological information, and other significant biological observations are given for each species. The treatments, written and reviewed by experts throughout the systematic botanical community, are based on original observations of herbarium specimens, and wherever possible, on living plants. These observations are supplemented by critical reviews of the literature.

Studies of insect nervous systems have made an immense contribution to our understanding of how a brain works and the way that the connections between constituent neurons are formed during development, For the first time these studies are brought together in The neurobiology of an insect brain, a personal account by a leading experimental neurobiologist and zoologist. By concentrating largely on one insect, the locust, this book unravels the mechanisms by which a brain integrates the vast array of sensory information to generate appropriate movements and behaviour. It first describes the basic structure of an insect brain and how this complex structure is formed during embryonic development. The cellular properties of the different types of neurons, and the way they are altered by neurosecretions are then analysed with respect to the integrative actions of these neurons during behaviour. Finally, the various movements that an insect performs are investigated at the cellular level to illustrate particular features of the integrative processing. Throughout, the book emphasises how knowledge of these simpler nervous systems contributes to our understanding of more complex brains, and at the same time provides the functional synthesis into which future molecular and computational studies can be woven. The neurobiology of an insect brain is an important milestone in our search for unifying principles of brain organisation and will be essential reading for students and research workers in neurobiology, behaviour, and entomology. our understanding

The Art of 2D Transesophageal Echocardiography provides in a practical and systematic way an overview of basic concepts and state of-the-art techniques in transesophageal echocardiography. It summarizes established application, provides hundreds of real-time videos of various cardiac diseases that expand the knowledge of every cardiologist, intensivist, and cardiovascular physicians in their daily practice of transesophageal echocardiography.

Flora of North America, Volume 22, is the first of five volumes covering monocots in North America, north of Mexico. The volume comprises of many groups of aquatic plants and the North American relatives of groups that have their greatest number of species located in the New World tropics. These include: the rush family (Juncaceae); cat-tails (Typhaceae); spiderworts (Commelinaceae); aroids (Araceae), and pondweeds (Potamogetonaceae). This volume includes thirty families, representing a diverse range of plant forms from marine Zosteraceae (eel-grasses) to stately Arecaceae (palms), and the naturalised exotic Zingiberaceae (gingers), Heliconiaceae (heliconias), and Musaceae (bananas).

The study of attention is central to psychology. In this work, Michael Posner, a pioneer in attention research, presents the science of attention in a larger social context, which includes our ability to voluntarily choose and act upon an object of thought. The volume is based on fifty years of research involving behavioral, imaging, developmental, and genetic methods. It describes three brain networks of attention that carry out the functions of obtaining and maintaining the alert state, orienting to sensory events, and regulating responses. The book ties these brain networks to anatomy, connectivity, development, and socialization and includes material on pathologies that involve attentional networks, as well as their role in education and social interaction.

It is well known that the class of steroid hormones known as estrogens have powerful effects on organs related to reproduction such as the uterus and the breast. What is less well known is that estrogens also profoundly modulate brain function and behavior. Estrogens, such as estradiol, can occur in brain as the result of ovarian secretion of the hormone into the blood that then finds its way to the brain. In male vertebrates, the testes secrete androgens, such as testosterone, into the blood and this class of steroid hormones can be converted into estrogens in the brain via the action of the enzyme aromatase which is expressed in the male brain in many species. Finally estradiol can be synthesized de novo from cholesterol as it has been shown in a variety of species that all the enzymes required to synthesize estrogens are expressed in the brain. This book collects chapters by experts in the field that considers, how estradiol is synthesized in the brain and what its effects are on a variety of behaviors. Special attention is paid to the enzyme aromatase that is distributed in discrete regions of the brain and is highly regulated in a sex specific and seasonal specific manner. Recently it has become clear that estrogens can act in the brain at two very different time scales, one is rather long lasting (days to weeks) and involves the modulation of gene transcription by the hormone-receptor complex. A second mode of action is much quicker and involves the action of estrogens on cell membranes that can result in effects on second messenger systems and ultimately behavior within minutes. Thus this book highlights novel views of estrogen action that are still under-appreciated namely that estrogens have significant effects on the male brain and that they can act on two very different times scales. This volume will be of interest to both basic researchers and clinicians interested in the action of estrogens.

This timely and up to date new edition of Biomedicine and Beatitude features an entirely new chapter on the ethics of bodily modification. It is also updated throughout to reflect the pontificate of Pope Francis, recent concerns including ethical issues raised by the COVID-19 pandemic, and feedback from the many instructors who used the first edition in the classroom

Largely through trial and error, filmmakers have developed engaging techniques that capture our sensations, thoughts, and feelings. Philosophers and film theorists have thought deeply about the nature and impact of these techniques, yet few scientists have delved into empirical analyses of our movie experience-or what Arthur P. Shimamura has coined "psychocinematics." This edited volume introduces this exciting field by bringing together film theorists, philosophers, psychologists, and neuroscientists to consider the viability of a scientific approach to our movie experience.

The evolution of a classic The new 12th edition of Introduction to Genetic Analysis takes this cornerstone textbook to the next level. The hallmark focuses on genetic analysis, quantitative problem solving, and experimentation continue in this new edition while incorporating robust updates to the science. Introduction to Genetic Analysis is now supported in Achieve, Macmillan's new online learning platform. Achieve is the culmination of years of development work put toward creating the most powerful online learning tool for biology students. It houses all of our renowned assessments, multimedia assets, e-books, and instructor resources in a powerful new platform.

Eye movements are a vital part of our interaction with the world. They play a pivotal role in perception, cognition, and education. Research in this field is now proceeding at a considerable pace and casting new light on how the eyes move and what information we can derive during the frequent and brief periods of fixation. However, the origins of this work are less well known, even though much of our knowledge was derived from this research with far more primitive equipment. This book is unique in tracing the history of eye movement research. It shows how great strides were made in this area before modern recording devices were available, especially in the measurement of nystagmus. When photographic techniques were adapted to measure discontinuous eye movements, from about 1900, many of the issues that are now basic to modern research were then investigated. One of the earliest cognitive tasks examined was reading, and it remains in the vanguard of contemporary research. Modern researchers in this field will be astonished at the subtleties of these early experimental studies and the ingenuity of interpretations that were advanced one and even two centuries ago. Though physicians often carried out the original eye movement research, later on it was pursued by psychologists - it is within contemporary neuroscience that we find these two strands reunited. Anyone interested in the origins of psychology and neuroscience will find much to stimulate and surprise them in this valuable new work.

A Best Book of 2020: The Washington Post * NPR * Chicago Tribune * Smithsonian A "remarkable" (Los Angeles Times), "seductive" (The Wall Street Journal) debut from the new cohost of Radiolab, Why Fish Don't Exist is a dark and astonishing tale of love, chaos, scientific obsession, and--possibly--even murder. "At one point, Miller dives into the ocean into a school of fish...comes up for air, and realizes she's in love. That's how I felt: Her book took me to strange depths I never imagined, and I was smitten." --The New York Times Book Review David Starr Jordan was a taxonomist, a man possessed with bringing order to the natural world. In time, he would be credited with discovering nearly a fifth of the fish known to humans in his day. But the more of the hidden blueprint of life he uncovered, the harder the universe seemed to try to thwart him. His specimen collections were demolished by lightning, by fire, and eventually by the 1906 San Francisco earthquake--which sent more than a thousand discoveries, housed in fragile glass jars, plummeting to the floor. In an instant, his life's work was shattered. Many might have given up, given in to despair. But Jordan? He surveyed the wreckage at his feet, found the first fish that he recognized, and confidently began to rebuild his collection. And this time, he introduced one clever innovation that he believed would at last protect his work against the chaos of the world. When NPR reporter Lulu Miller first heard this anecdote in passing, she took Jordan for a fool--a cautionary tale in hubris, or denial. But as her own life slowly unraveled, she began to wonder about him. Perhaps instead he was a model for how to go on when all seemed lost. What she would unearth about his life would transform her understanding of history, morality, and the world beneath her feet. Part biography, part memoir, part scientific adventure, Why Fish Don't Exist is a wondrous fable about how to persevere in a world where chaos will always prevail.

'Gow reinvents what it means to be a guardian of the countryside.'-Guardian 'This authentic, impassioned manifesto-cum-memoir will hopefully have a major impact on what is likely to be a long-running controversy.'-The Spectator 'Gow has a fire in his belly. We need more like him.'-BBC Wildlife Magazine A Waterstones Best Nature Writing Book of 2020 'Bringing Back the Beaver is a hilarious, eccentric and magnificent account of a struggle . . . to reintroduce a species crucial to the health of our ecosystems.'-George Monbiot Bringing Back the Beaver is farmer-turned-ecologist Derek Gow's inspirational and often riotously funny first-hand account of how the movement to rewild beavers into the British landscape became the single most dramatic and subversive nature conservation act of the modern era. Since the early 1990s - in the face of outright opposition from government, landowning elites and even some conservation professionals - Gow has imported, quarantined and assisted the reestablishment of beavers in waterways across England and Scotland. With a foreword by bestselling author of Wilding, Isabella Tree, Bringing Back the Beaver makes a passionate case as to why the return of one of nature's great problem solvers will be critical as part of a sustainable fix for the UK's growing flooding problems, whilst ensuring the creation of essential landscapes that enable the broadest spectrum of Britain's wildlife to thrive. 'It is wonderful to see that beavers are now officially back on the list of native species, having been absent for so long . . . far too long!'-Dame Judi Dench

A new, fully updated edition of David Attenborough's groundbreaking Life on Earth. David Attenborough's unforgettable meeting with gorillas became an iconic moment for millions of television viewers. Life on Earth, the series and accompanying book, fundamentally changed the way we view and interact with the natural world setting a new benchmark of quality, influencing a generation of nature lovers. Told through an examination of animal and plant life, this is an astonishing celebration of the evolution of life on earth, with a cast of characters drawn from the whole range of organisms that have ever lived on this planet. Attenborough's perceptive, dynamic approach to the evolution of millions of species of living organisms takes the reader on an unforgettable journey of discovery from the very first spark of life to the blue and green wonder we know today. To celebrate the 40th anniversary of the book's first publication, David Attenborough revisited Life on Earth, completely updating and adding to the original text, taking account of modern scientific discoveries from around the globe. This paperback edition also includes more than 60 full colour photographs, chosen by the author to help illustrate the book in a much greater way than was possible forty years ago. This updated edition provides a fitting tribute to an enduring wildlife classic, destined to enthral the generation who saw it when first published and bring it alive for a whole new generation.

Sentient assembles a menagerie of zoological creatures – from land, air, sea and all four corners of the globe – to understand what it means to be human. Through their eyes, ears, skins, tongues and noses, the furred, finned and feathered reveal how we sense and make sense of the world, as well as the untold scientific revolution stirring in the field of human perception.

The harlequin mantis shrimp can throw a punch that can fracture aquarium walls but, more importantly, it has the ability to see a vast range of colours. The ears of the great grey owl have such unparalleled range and sensitivity that they can hear twenty decibels lower than the human ear. The star-nosed mole barely fills a human hand, seldom ventures above ground and poses little threat unless you are an earthworm, but its miraculous nose allows it to catch those worms at astonishing speed – as little as one hundred and twenty milliseconds. Here, too, we meet the four-eyed spookfish and its dark vision; the vampire bat and its remarkable powers of touch; the bloodhound and its hundreds of millions of scent receptors, as well as the bar-tailed godwit, the common octopus, giant peacocks, cheetahs and golden orb-weaving spiders. Each of these extraordinary creatures illustrates the sensory powers that lie dormant within us.

In this captivating book, Jackie Higgins explores this evolutionary heritage and, in doing so, enables us to subconsciously engage with the world in ways we never knew possible.