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Thermoregulation, Part I: From Basic Neuroscience to Clinical Neurology, Volume 154, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function. In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions.
Expanding upon one of the most-read "New York Times Magazine"
features of 2012, "Smarter" penetrates the hot new field of
intelligence research to reveal what researchers call a revolution
in human intellectual abilities. Shattering decades of dogma,
scientists began publishing studies in 2008 showing that "fluid
intelligence" - the ability to learn, solve novel problems, and get
to the heart of things - can be increased through training.
This book brings together contributions from scientists and educators at the forefront of interdisciplinary research efforts involving neuroscience and education. It includes consideration of what we know about brain function that may be relevant to educational areas including reading, mathematics, music and creativity. The increasing interest of educators in neuroscience also brings dangers with it, as evidenced by the proliferation of neuromyths within schools and colleges. For this reason, it also reviews some of the more prominent misconceptions, as well as exploring how educational understanding can be constructed in the future that includes concepts from neuroscience more judiciously.
This book will be of interest to educators, policymakers and scientists seeking fresh perspectives on how we learn.
This book was published as a special issue in Educational Research, a journal of the National Foundation for Educational Research (NFER).
"We are buried beneath mountains of fast-accumulating data. In such circumstances, this book, rather than adding to the data load, aims to offer real understanding." -James Lovelock Human beings are extraordinary creatures. Intelligent, agile, and curious, we have adapted and invented our way to becoming the most important species on the planet. So great is the extent of our influence, that many speak of a new geological era, the Anthropocene, an age defined by human-induced change to the blue and green globe we call home. Our lofty status comes with responsibility as much as possibility: How should we approach our present and future? What knowledge should we carry with us? Conceived by James Lovelock, inventor of the Gaia theory, this illustrated essay collection brings together an all-star lineup of thinkers and scientists to offer essential understanding about who we are, how we live, and where we might be going. Much as the Gaia theory considers our Earth as an integrated whole of living systems, The Earth and I encourages holistic understanding. Across 12 chapters, we take in both the intricate details and immense structures of our species and our planet, from our ever-expanding universe to our minuscule but mighty cells. We see stellar explosions and the layers of life beneath our feet, delve into the neuroscience of decision-making, get to grips with our climate, and contemplate our increasing intimacy with technology. The book's world-class contributors include quantum physicist Lisa Randall, Astronomer Royal Martin Rees, Pulitzer Prize-winning biologist Edward O. Wilson, and Nobel Prize-winning neuroscientist Eric Kandel. With lively illustrations from British artist Jack Hudson, the result is an inspiration for curious minds young and old, and a trusted tool kit for an informed and enlightened future.
The papers collected in this volume examine moral enhancement: the idea that we should morally improve people through the manipulation of their biological constitution. Whether moral enhancement is possible or even desirable is highly controversial. Proponents argue that it is necessary if we are to address various social ills and avert catastrophic climate change. Detractors have raised a variety of concerns, some of a practical nature and others of principle. Perhaps most fundamentally, however, the proposal forces us to ask anew what being moral actually means, in order for the idea of moral enhancement to make sense at all. The present collection both addresses these issues and moves the debate beyond its current parameters, bringing together authors with a wide range of perspectives and areas of expertise. Chapters variously draw on experimental psychology, social philosophy, pragmatism, Kantian and Aristotelian moral philosophy, and the ethics of care, sex, and psychedelics.
Why our brains aren't built for media multitasking, and how we can learn to live with technology in a more balanced way. "Brilliant and practical, just what we need in these techno-human times."-Jack Kornfield, author of The Wise Heart Most of us will freely admit that we are obsessed with our devices. We pride ourselves on our ability to multitask-read work email, reply to a text, check Facebook, watch a video clip. Talk on the phone, send a text, drive a car. Enjoy family dinner with a glowing smartphone next to our plates. We can do it all, 24/7! Never mind the errors in the email, the near-miss on the road, and the unheard conversation at the table. In The Distracted Mind, Adam Gazzaley and Larry Rosen-a neuroscientist and a psychologist-explain why our brains aren't built for multitasking, and suggest better ways to live in a high-tech world without giving up our modern technology. The authors explain that our brains are limited in their ability to pay attention. We don't really multitask but rather switch rapidly between tasks. Distractions and interruptions, often technology-related-referred to by the authors as "interference"-collide with our goal-setting abilities. We want to finish this paper/spreadsheet/sentence, but our phone signals an incoming message and we drop everything. Even without an alert, we decide that we "must" check in on social media immediately. Gazzaley and Rosen offer practical strategies, backed by science, to fight distraction. We can change our brains with meditation, video games, and physical exercise; we can change our behavior by planning our accessibility and recognizing our anxiety about being out of touch even briefly. They don't suggest that we give up our devices, but that we use them in a more balanced way.
What are you? Obviously, you are a person with human ancestors that can be plotted on a family tree, but you have other identities as well. According to evolutionary biologists, for example, you are a member of the species Homo sapiens. To a microbiologist, though, you are a collection of cells, each of which has its own cellular ancestry. A geneticist might point out that besides these identities, you can be understood as a gene-replication machine, which can be plotted on a "genetic tree." Finally a physicist will give a rather different answer to the identity question: you can be understood as a collection of atoms, each of which has a very long history. Some have been around since the Big Bang, and others are the result of nuclear fusion that took place within a star. Not only that, but most of your atoms belonged to other living things before joining you. From your atoms' point of view, then, you are just a way station on a multibillion-year-long journey. You: A Natural History offers a multi-disciplinary investigation of your hyper-extended family tree, going all the way back to the Big Bang. And while your family tree may contain surprises, your hyper-extended history contains some truly amazing stories. As the result of learning more about who and what you are, and about how you came to be here, you will likely see the world around you with fresh eyes. You will also become aware of all the one-off events that had to take place for your existence to be possible: stars had to explode, the earth had to be hit 4.5 billion years ago by a planetesimal and 65 million years ago by an asteroid, microbes had to engulf microbes, the African savanna had to undergo climate change, and of course, any number of your direct ancestors had to meet and mate. It is difficult, on becoming aware of just how contingent your own existence is, not to feel very lucky to be part of our universe.
Winner of the IENE Project Award 2016. This authoritative volume brings together some of the world s leading researchers, academics, practitioners and transportation agency personnel to present the current status of the ecological sustainability of the linear infrastructure primarily road, rail and utility easements that dissect and fragment landscapes globally. It outlines the potential impacts, demonstrates how this infrastructure is being improved, and how broad ecological principles are applied to mitigate the impact of road networks on wildlife. Research and monitoring is an important aspect of road ecology, encompassing all phases of a transportation project. This book covers research and monitoring to span the entire project continuum starting with planning and design, through construction and into maintenance and management. It focuses on impacts and solutions for species groups and specific regions, with particular emphasis on the unique challenges facing Asia, South America and Africa. Other key features: * Contributions from authors originating from over 25 countries, including from all continents * Each chapter summarizes important lessons, and includes lists of further reading and thoroughly up to date references * Highlights principles that address key points relevant to all phases in all road projects * Explains best-practices based on a number of successful international case studies * Chapters are "stand-alone", but they also build upon and complement each other; extensive cross-referencing directs the reader to relevant material elsewhere in the book Handbook of Road Ecology offers a comprehensive summary of approximately 30 years of global efforts to quantify the impacts of roads and traffic and implement effective mitigation. As such, it is essential reading for those involved in the planning, design, assessment and construction of new roads; the management and maintenance of existing roads; and the modifying or retrofitting of existing roads and problem locations. This handbook is an accessible resource for both developed and developing countries, including government transportation agencies, Government environmental/conservation agencies, NGOs, and road funding and donor organisations.
Experts explore the maturation of nonlinear brain dynamics from a developmental perspective and consider the relationship of neurodevelopmental disorders to early disruption in dynamic coordination. This volume in the Strungmann Forum Reports series explores the complex mechanisms that accompany the dynamic processes by which the brain evolves and matures. Integrating perspectives from multiple disciplines, the book identifies knowledge gaps and proposes innovative ways forward for this emerging area of cross-disciplinary study. The contributors examine maturation of nonlinear brain dynamics across systems from a developmental perspective and relate these organizing networks to the establishment of normative cognition and pathology seen in many neurodevelopmental disorders. The book looks at key mechanistic questions, including: What role does dynamic coordination play in the establishment and maintenance of brain networks and structural and functional connectivity? How are local and global functional networks assembled and transformed over normative development? To what degree do oscillatory patterns vary across development? What is the impact of critical periods, and which factors initiate and terminate such periods? It also explores the potential of new technologies and techniques to enhance understanding of normative development and to enable early identification and remediation of neurodevelopmental and neuropsychiatric disorders that may result from early disruption in dynamic coordination. Contributors Sylvain Baillet, Yehezkel Ben-Ari, April A. Benasich, Olivier Bertrand, Gyorgy Buzsaki, Alain Chedotal, Sam M. Doesburg, Gordin Fishell, Adriana Galvan, Jennifer N. Gelinas, Jay Giedd, Pierre Gressens, Ileana L. Hanganu-Opatz, Rowshanak Hashemiyoon, Takao K. Hensch, Suzana Herculano-Houzel, Mark Hubener, Mark, Matthias Kaschube, Michael S. Kobor, Bryan Kolb, Thorsten Kolling, Jean-Philippe Lachaux, Ulman Lindenberger, Heiko J. Luhmann, Hannah Monyer, Sarah R. Moore, Charles A. Nelson III, Tomas Paus, Patrick L. Purdon, Pasko Rakic, Urs Ribary, Akira Sawa, Terrence J. Sejnowski, Wolf Singer, Cheryl L. Sisk, Nicholas C. Spitzer, Michael P. Stryker, Migranka Sur, Peter J. Uhlhaas
Presenting a global and interdisciplinary approach to plant ecology, this much-awaited new edition of the book Plants and Vegetation integrates classical themes with the latest ideas, models, and data. Keddy draws on extensive teaching experience to bring the field to life, guiding students through essential concepts with numerous real-world examples and full-colour illustrations throughout. The chapters begin by presenting the wider picture of the origin of plants and their impact on the Earth, before exploring the search for global patterns in plants and vegetation. Chapters on resources, stress, competition, herbivory, and mutualism explore causation, and a concluding chapter on conservation addresses the concern that one-third of all plant species are at risk of extinction. The scope of this edition is broadened further by a new chapter on population ecology, along with extensive examples including South African deserts, the Guyana Highlands of South America, Himalayan forests and arctic alpine environments.
Bringing together the ideas of experts from around the world, this incisive text offers cutting-edge perspectives on the risk analysis and governance of genetically modified organisms (GMOs), supporting effective and informed decision-making in developing countries. Comprised of four comprehensive sections, this book covers: integrated risk analysis and decision making, giving an overview of the science involved and examining risk analysis methods that impact decision-making on the release of GMOs, particularly in developing countries; diversification of expertise involved in risk analysis and practical ways in which the lack of expertise in developing countries can be overcome; risk analysis based regulatory systems and how they can be undermined by power relationships and socio-political interests, as well as strategies for improving GMO policy development and regulatory decision-making; and case studies from developing countries providing lessons based on real-world experience that can inform our current thinking.
The Princeton Guide to Evolution is a comprehensive, concise, and authoritative reference to the major subjects and key concepts in evolutionary biology, from genes to mass extinctions. Edited by a distinguished team of evolutionary biologists, with contributions from leading researchers, the guide contains some 100 clear, accurate, and up-to-date articles on the most important topics in seven major areas: phylogenetics and the history of life; selection and adaptation; evolutionary processes; genes, genomes, and phenotypes; speciation and macroevolution; evolution of behavior, society, and humans; and evolution and modern society. Complete with more than 100 illustrations (including eight pages in color), glossaries of key terms, suggestions for further reading on each topic, and an index, this is an essential volume for undergraduate and graduate students, scientists in related fields, and anyone else with a serious interest in evolution. * Explains key topics in some 100 concise and authoritative articles written by a team of leading evolutionary biologists * Contains more than 100 illustrations, including eight pages in color * Each article includes an outline, glossary, bibliography, and cross-references * Covers phylogenetics and the history of life; selection and adaptation; evolutionary processes; genes, genomes, and phenotypes; speciation and macroevolution; evolution of behavior, society, and humans; and evolution and modern society
This book includes invited contributions presenting the latest research on the oceanography and environment of the Red Sea. In addition to covering topics relevant to research in the region and providing insights into marine science for non-experts, it is also of interest to those involved in the management of coastal zones and encourages further research on the Red Sea
Tucked away in Siberia, there are furry, four-legged creatures with wagging tails and floppy ears that are as docile and friendly as any lapdog. But, despite appearances, these are not dogs-they are foxes. They are the result of the most astonishing experiment in breeding ever undertaken-imagine speeding up thousands of years of evolution into a few decades. In 1959, biologists Dmitri Belyaev and Lyudmila Trut set out to do just that, by starting with a few dozen silver foxes from fox farms in the USSR and attempting to recreate the evolution of wolves into dogs in real time in order to witness the process of domestication. This is the extraordinary, untold story of this remarkable undertaking. Most accounts of the natural evolution of wolves place it over a span of about 15,000 years, but within a decade, Belyaev and Trut's fox breeding experiments had resulted in puppy-like foxes with floppy ears, piebald spots, and curly tails. Along with these physical changes came genetic and behavioral changes, as well. The foxes were bred using selection criteria for tameness, and with each generation, they became increasingly interested in human companionship. Trut has been there the whole time, and has been the lead scientist on this work since Belyaev's death in 1985, and with Lee Dugatkin, biologist and science writer, she tells the story of the adventure, science, politics, and love behind it all. In How to Tame a Fox, Dugatkin and Trut take us inside this path-breaking experiment in the midst of the brutal winters of Siberia to reveal how scientific history is made and continues to be made today. To date, fifty-six generations of foxes have been domesticated, and we continue to learn significant lessons from them about the genetic and behavioral evolution of domesticated animals. How to Tame a Fox offers an incredible tale of scientists at work, while also celebrating the deep attachments that have brought humans and animals together throughout time.
'A great journalist with a whip-like satirical prose style... Wolfe's great gift is to make the heavy seem light and this book is such an entertaining polemic that I read it in a day and immediately wanted to read it again.' - Bryan Appleyard, Sunday Times Tom Wolfe, whose legend began in journalism, takes us on an eye-opening journey through language. The Kingdom of Speech is a paradigm-shifting argument that speech - not evolution - is responsible for humanity's complex societies and achievements. From Alfred Russel Wallace, the Englishman who beat Darwin to the theory of natural selection but later renounced it, and through the controversial work of modern-day anthropologist Daniel Everett, who defies the current wisdom that language is hard-wired in humans, Wolfe examines the solemn, long-faced, laugh-out-loud zig-zags of Darwinism, old and Neo, and finds it irrelevant here in our Kingdom of Speech.
Two distinguished scientists encouraged Warwick Collins in writing his revolutionary theory of evolution. Professor Freeman Dyson, one of the world's leading theoretical physicists, wrote, "I like your theory, and think it has a good chance of being right." He added, "Darwin would have liked your theory." Professor Donald Braben, a nuclear physicist who directed a series of wide-ranging research programs at BP, responded, "Hierarchically speaking, variation is of greater significance than selection. I agree, therefore, that if silent gene theory were proved correct, it would be the more complete theory, as Einstein's is compared with Newton's." Charles Darwin wrote in The Origin of Species that ..". unless profitable variations do occur, natural selection can do nothing." As Darwin recognized, natural selection, far from increasing variation within species, reduces variation constantly in favor of an optimum type. What then is the true source of variation in evolutionary systems? It is a question which has obsessed Warwick Collins, a novelist who had studied biology at university, for much of his adult life. He proposed in March 2000 that the required degree of variation could be achieved if large numbers of inert or silent genes existed within the genome. Such genes, because they do not code for physical characteristics, could freely mutate over time without deleteriously affecting the host organism. At a later stage they could be switched on, by largely random processes, and generate exotic new variants. Remarkably, his description of silent genes was found to correspond precisely with the so-called junk genes. These are found in all species, forming the great majority of genes in multicellular species and rising to 98.5% of the genome in humans. Until then their function had proved mysterious. In addition, Collins's theory predicted a number of features of the silent or junk genes which have since been increasingly verified by recent research: for example, that they could become active and begin to code, and that they influenced other genes. It is now widely accepted that, just as Collins predicted, the vast majority of significant mutation in the genomes of complex species arises from the silent genes. But Collins's powerful and ambitious theory moves well beyond the molecular realm. He argues that while natural selection is a major force in evolution, it is primarily negative and entropic. Instead, the great driver of complex evolution is the range of variation created by the silent genes. As Professor Donald Braben writes in his illuminating foreword, "Collins is proposing a general evolutionary theory which, if it continues to be supported by the data, may in due course come to rival Darwin's theory that evolution is driven by natural selection."
Clustering techniques are increasingly being put to use in the analysis of high-throughput biological datasets. Novel computational techniques to analyse high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. This book details the complete pathway of cluster analysis, from the basics of molecular biology to the generation of biological knowledge. The book also presents the latest clustering methods and clustering validation, thereby offering the reader a comprehensive review of clustering analysis in bioinformatics from the fundamentals through to state-of-the-art techniques and applications. Key Features: * Offers a contemporary review of clustering methods and applications in the field of bioinformatics, with particular emphasis on gene expression analysis * Provides an excellent introduction to molecular biology with computer scientists and information engineering researchers in mind, laying out the basic biological knowledge behind the application of clustering analysis techniques in bioinformatics * Explains the structure and properties of many types of high-throughput datasets commonly found in biological studies * Discusses how clustering methods and their possible successors would be used to enhance the pace of biological discoveries in the future * Includes a companion website hosting a selected collection of codes and links to publicly available datasets
Paul Thagard uses new accounts of brain mechanisms and social interactions to forge theories of mind, knowledge, reality, morality, justice, meaning, and the arts. Natural Philosophy brings new methods for analyzing concepts, understanding values, and achieving coherence. It shows how to unify the humanities with the cognitive and social sciences. How can people know what is real and strive to make the world better? Philosophy is the attempt to answer general questions about the nature of knowledge, reality, and values. Natural Philosophy pursues these questions by drawing heavily on the sciences and finds no room for supernatural entities such as souls, gods, and possible worlds. It provides original accounts of the traditional branches of philosophy, including epistemology, metaphysics, ethics, and aesthetics. Rather than reducing the humanities to the sciences, this book displays fertile interconnections that show that philosophical questions and artistic practices can be much better understood by considering how human brains operate and interact in social contexts. The sciences and the humanities are interdependent, because both the natural and social sciences cannot avoid questions about methods and values that are primarily the province of philosophy. This book belongs to a trio that includes Brain-Mind: From Neurons to Consciousness and Creativity and Mind-Society: From Brains to Social Sciences and Professions. They can be read independently, but together they make up a Treatise on Mind and Society that provides a unified and comprehensive treatment of the cognitive sciences, social sciences, professions, and humanities.
Forty years ago, Israeli psychologists Daniel Kahneman and Amos Tversky wrote a series of breathtakingly original studies undoing our assumptions about the decision-making process. Their papers showed the ways in which the human mind erred, systematically, when forced to make judgments in uncertain situations. Their work created the field of behavioral economics, revolutionized Big Data studies, advanced evidence-based medicine, led to a new approach to government regulation, and made much of Michael Lewis's own work possible. Kahneman and Tversky are more responsible than anybody for the powerful trend to mistrust human intuition and defer to algorithms. The Undoing Project is about a compelling collaboration between two men who have the dimensions of great literary figures. They became heroes in the university and on the battlefield--both had important careers in the Israeli military--and their research was deeply linked to their extraordinary life experiences. Amos Tversky was a brilliant, self-confident warrior and extrovert, the center of rapt attention in any room; Kahneman, a fugitive from the Nazis in his childhood, was an introvert whose questing self-doubt was the seedbed of his ideas. They became one of the greatest partnerships in the history of science, working together so closely that they couldn't remember whose brain originated which ideas, or who should claim credit. They flipped a coin to decide the lead authorship on the first paper they wrote, and simply alternated thereafter. This story about the workings of the human mind is explored through the personalities of two fascinating individuals so fundamentally different from each other that they seem unlikely friends or colleagues. In the process they may well have changed, for good, mankind's view of its own mind.
Why are people nice to each other? What are the reasons for altrusim? Matt Ridley explains how the human mind has evolved a special instinct for social exchange, offering a lucid and persuasive argument about the paradox of human benevolence.
Over half a century of brilliant scientific detective work, the Nobel Prize-winning biologist Karl von Frisch learned how the world, looks, smells, and tastes to a bee. More significantly, he discovered their dance language and their ability to use the sun as a compass. Intended to serve as an accessible introduction to one of the most fascinating areas of biology, Bees (first published in 1950 and revised in 1971), reported the startling results of his ingenious and revolutionary experiments with honeybees.
In his revisions, von Frisch updated his discussion about the phylogenetic origin of the language of bees and also demonstrated that their color sense is greater than had been thought previously. He also took into consideration the electrophysiological experiments and electromicroscopic observations that have supplied more information on how the bee analyzes polarized light to orient itself and how the olfactory organs on the bee's antennae function.
Now back in print after more than two decades, this classic and still-accurate account of the behavior patterns and sensory capacities of the honeybee remains a book "written with a simplicity, directness, and charm which all who know him will recognize as characteristic of its author. Any intelligent reader, without scientific training, can enjoy it." Yale Review"
Darwinism is fast becoming an orthodoxy of modern thought, a framework within which a wide range of knowledge communities conduct their discourse. Ever since its formation, Darwinian theory has experienced a close, though not always comfortable, association with economics. Evolutionary economists now appear to show little concern for the consistency of knowledge in their embrace of Darwinism. Darwinism and Evolutionary Economics brings together contributions from eminent authors who, building on Darwin's own insights and on developments in evolutionary theory, offer challenging views on how economics can use evolutionary ideas effectively. This collection of critical essays provides a thorough examination of the application of Darwinian theory to economic thought, and will appeal to evolutionary economists and all those with an interest in Darwin, innovation and evolutionary science.
The true role of biology in determining sexual orientation is an oft-debated issue in both the popular media and scientific communities, and evaluating the literature on the topic can be daunting. "Nature's Choice: What Science Reveals About the Biological Origins of Sexual Orientation" offers both a comprehensive review of the scientific literature and a fresh perspective on this complex and politically charged subject. Respected researcher, speaker, and author Dr. Cheryl L. Weill offers readers of all backgrounds an enlightening analysis of findings from over twenty years of research on the factor of biology in the determination of sexual orientation. "Nature's Choice: What Science Reveals About the Biological Origins of Sexual Orientation" brilliantly distills complicated studies and research findings dealing with brain anatomy, genetics, sex-typical behavior in children, auditory, startle reflex, and many other areas. Spanning a wide range of important topics including human sexual development and the effects of hormones, Ellis and Ames' Gestational Neurohormonal Theory, the ins, outs, and implications of how scientific research is funded, and a model of the role of testosterone in determining human sexuality, "Nature's Choice" is an exciting book to educate and inspire readers from scientific and non-scientific backgrounds equally. For a complete Instructor's Manual and other supplementary materials see: www.natures-choice.info
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