Osteobiographies: The Discovery, Interpretation and Repatriation of Human Remains contextualizes repatriation, or the transfer of authority for human skeletal remains from the perspective of bioarchaelogists and evolutionary biologists. It approaches repatriation from a global perspective, touching upon the most well-known Native American Graves Protection and Repatriation Act (NAGPRA) legislation of the United States, while also covering Canada and African countries. The book focuses on the stories behind human skeletons, analyzing their biological factors to determine evolution patterns. Sections present an overview of anatomy, genomics, and stable isotopes from dietary and environmental factors, and how to identify these in skeletal remains. The book then goes on to discuss European-origin, North American, and African paleopathology, ancient DNA links, and cultural issues and implications around repatriation. It concludes with case studies to show how information from archaeologically derived skeletons is vital to understanding human evolution and provide respectful histories behind the remains.

The 2021 IPCC report made one thing crystal clear - global climate change is here to stay. Time is up. We need to act or climate change will lead to inconceivable suffering by billions of people. Buying Time for Climate Action is the combined narrative of world class experts, all committed to help humanity survive its largely self-induced destructive course. Changing that course requires urgent action. Determining which actions will lead to helpful change requires insights into the stumbling blocks that always emerge when actions aimed at change are planned, resulting in lost time. The experts who contributed to this volume, through their expertise, networks, wisdom and creativity, have largely concluded that the way to cope with the stumbling blocks is to avoid them by focusing on grassroots initiatives. Their narratives and discussions, presented in this book, highlight such thinking.The book is essential reading for anyone committed to help avoid an existential disaster for humanity, and ready to move plans into effective action.

The 2021 IPCC report made one thing crystal clear - global climate change is here to stay. Time is up. We need to act or climate change will lead to inconceivable suffering by billions of people. Buying Time for Climate Action is the combined narrative of world class experts, all committed to help humanity survive its largely self-induced destructive course. Changing that course requires urgent action. Determining which actions will lead to helpful change requires insights into the stumbling blocks that always emerge when actions aimed at change are planned, resulting in lost time. The experts who contributed to this volume, through their expertise, networks, wisdom and creativity, have largely concluded that the way to cope with the stumbling blocks is to avoid them by focusing on grassroots initiatives. Their narratives and discussions, presented in this book, highlight such thinking.The book is essential reading for anyone committed to help avoid an existential disaster for humanity, and ready to move plans into effective action.

Encyclopedia of Mycology, Two Volume Set provides a broad and multidisciplinary overview of a subject whose importance in an ecosystem is becoming more and more universally accepted with its close links to botany, microbiology, biotechnology and medicine. While there are many subject-specific works available on the topics presented, from a multidisciplinary point-of-view it is difficult to find a reliable and updated source such as this one. This work is unique in that it is a one-stop-shop on every topic area of this exciting field.

Understanding the human mind and how it relates to the world that we experience has challenged philosophers for centuries. How then do we even begin to think about 'minds' that are not human? Science now has plenty to say about the properties of mind. In recent decades, the mind - both human and otherwise - has been explored by scientists in fields ranging from zoology to astrobiology, computer science to neuroscience. Taking a uniquely broad view of minds and where they might be found - including in plants, aliens, and God - Philip Ball pulls these multidisciplinary pieces together to explore what sorts of minds we might expect to find in the universe. In so doing, he offers for the first time a unified way of thinking about what minds are and what they can do, arguing that in order to understand our own minds and imagine those of others, we need to move on from considering the human mind as a standard against which all others should be measured, and to think about the 'space of possible minds'. By identifying and mapping out properties of mind without prioritizing the human, Ball sheds new light on a host of fascinating questions. What moral rights should we afford animals, and can we understand their thoughts? Should we worry that AI is going to take over society? If there are intelligent aliens out there, how could we communicate with them? Should we? Understanding the space of possible minds also reveals ways of making advances in understanding some of the most challenging questions in contemporary science: What is thought? What is consciousness? And what (if anything) is free will? The more we learn about the minds of other creatures, from octopuses to chimpanzees, and to imagine the potential minds of computers and alien intelligences, the greater the perspective we have on if and how our own is different. Ball's thrillingly ambitious The Book of Minds about the nature and existence of minds is more mind-expanding than we could imagine. In this fascinating panorama of other minds, we come to better know our own.

Evidence based or empirically supported psychotherapies are becoming more and more important in the mental health fields as the users and financers of psychotherapies want to choose those methods whose effectiveness are empirically shown. Cognitive-behavioral psychotherapies are shown to have empirical support in the treatment of a wide range of psychological/psychiatric problems. As a cognitive-behavioral mode of action, Problem Solving Therapy has been shown to be an effective psychotherapy approach in the treatment and/or rehabilitation of persons with depression, anxiety, suicide, schizophrenia, personality disorders, marital problems, cancer, diabetes-mellitus etc.

Mental health problems cause personal suffering and constitue a burden to the national health systems. Scientific evidence show that effective problem solving skills are an important source of resiliency and individuals with psychological problems exhibit a deficiency in effective problem solving skills. Problem solving therapy approach to the treatment and/or rehabilitation of emotional problems assumes that teaching effective problem solving skills in a therapeutic relationship increases resiliency and alleviates psychological problems.The book, in the first chapters, gives information on problem solving and the role of problem-solving in the etiology and the treatment of different forms of mental health problems. In the later chapters, it concentrates on psychotherapy, assessment and procedures of problem solving therapy. At the end it provides a case study.

This book integrates theory, research & practiceand provides a comprehensive appreciation of problem solving therapy.Itcontains empirical evidence and applied focus for problem solving therapy which provides a scientific base and best practices.The bookalso highlights the problem solving difficulties of persons with specific disorders and provides a better understanding of the relevance of problem solving therapy to a broad range of emotional problems. "

Global Emergency of Mental Disorders is a comprehensive, yet easy-to-read overview of the neurodevelopmental basis of multiple mental disorders and their accompanying consequences, including addiction, suicide and homelessness. Compared to other references that examine the treatment of psychiatric disorders, this book uniquely focuses on their neurodevelopment. It is designed for neuroscience, psychiatry, psychology students, and various other clinical professions. With chapters on anxiety, depression, schizophrenia and others, this volume provides information about incidence, prevalence and mortality rates in addition to developmental origins. With millions worldwide affected, this book will be an invaluable resource.

Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43's structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases. This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders.

Exploring the environmental effects of animal agriculture, fishing, and hunting, Eating Earth exposes critical common ground between earth and animal advocacy. The first chapter (animal agriculture) examines greenhouse gas emissions and climate change, manure and dead zones, freshwater depletion, deforestation, predator control, land and useincluding the ranching industries public lands subsidies. Chapter two first examines whether or not the consumption of fish is healthy and outlines morally relevant aspects of fish physiology, then scrutinizes the fishing industry, documenting the silent collapse of ocean ecosystems and calling attention to the indiscriminate nature of hooks and nets, including the problem of bycatch and what this means for endangered species and fragile seascapes. Chapter three outlines the historic link between the U. S. Government, wildlife management, and hunters, then systematically unravels common beliefs about sport hunting, such as the belief that hunters are essential to wildlife conservation, that contemporary hunting qualifies as a tradition, and that hunting is merciful, economical, or rooted in fair chase. At the end of each chapter, Kemmerer examines possible solutions to problems presented, such as sustainable meats, organic and local, grass fed, aquaculture, new fishing technologies, and enhanced regulations. Eating Earth offers a concise examination of the environmental effects of dietary choice, clearly presenting the many reasons why dietary choice ought to be front and center for environmentalists. Kemmerers writing, supported by nearly 80 graphs and summary slides, is clear, straightforward, and punctuated with wry humor.

This book focuses on the role of the endocannabinoid system in local and systemic inflammation, with individual chapters written by experts in the field of cannabinoid research and medicine. The topics explore the actions of the endocannabinoid system on the immune system, including neuroinflammation in autoimmune disorders such as multiple sclerosis, and in neurodegenerative disorders such as Huntington's and Alzheimer's, as well as local and systemic inflammatory conditions affecting organs including the eye (uveitis and corneal inflammation), the bladder (interstitial cystitis), pancreas (diabetes), cardiovascular system (stroke), joints (arthritis), and sepsis. The objective of this book is to provide knowledge transfer on the use of cannabinoids in inflammatory disease by critically examining preclinical and clinical research on the immunomodulatory actions of the endocannabinoid system, with specific emphasis on the actions of cannabinoids in diseases where inflammation is a prominent component. By drawing these results together, we seek to provide further understanding of the complexities of endocannabinoid system modulation of immune function and identify potential uses and limitations for cannabinoid-based therapeutics.

New Horizons in Evolution is a compendium of the latest research, analyses, and theories of evolutionary biology. Chapters are collected from the international symposium held by the Board of Governors of the University of Haifa to honor Dr. Eviatar Nevo, founder and director of the Institute of Evolution. This book includes material written by top global scientists. Such detailed summaries and recent advances include topics like genomics, epigenetics, evolutionary theory, and the evolution of cancer. This book analyzes evolutionary biology of animals, such as lizards and subterranean mammals. It also discusses agricultural evolution, specifically the vital wheat crop in various climates and locations. Each chapter contributes the most up-to-date knowledge of evolution's role in speciation, adaptation, and regulation. New Horizons in Evolution is a valuable resource for researchers involved in evolution, evolutionary biology, and evolutionary theory. Advanced undergraduate and graduate students in evolutionary biology courses will also find this useful due to the high expertise level and latest knowledge available through this resource.

Biochemical and Molecular Basis of Pediatric Disease, Fifth Edition has been a well-respected reference in the field for decades. This revision continues the strong focus on understanding the pathogenesis of pediatric disease, emphasizing not only the important role of the clinical laboratory in defining parameters that change with the disease process, but also the molecular basis of many pediatric diseases.

Handbook of Thermoset-Based Biocomposites is a three-volume set that provides a comprehensive review on the recent developments, characterization, and applications of natural fiber-reinforced biocomposites. An in-depth look at hybrid composites, nanofillers, and natural fiber reinforcement is divided into three books on polyester, vinyl ester, and epoxy composites. The volumes explore the widespread applications of natural fiber-reinforced polyester, vinyl ester, and epoxy composites ranging from the aerospace sector, automotive parts, construction and building materials, sports equipment, and household appliances. Investigating the physio-chemical, mechanical, and thermal properties of these composites, the volumes also consider the influence of hybridization, fibre architecture, and fibre-ply orientation. This three-volume set serves as a useful reference for researchers, graduate students, and engineers in the field of composites.

Successes and Challenges of NK Immunotherapy: Increasing Anti-tumor Efficacy describes the unique therapeutic applications of NK cells to fight cancers and eliminate the bulk and subset of cancer stem cells responsible for metastasis, relapse and recurrences. The book provides information on the development, engineering, mechanisms of action, response to various preclinical models, and applications in various clinical trials. Sections cover the development of highly engineered cytotoxic NK cells, their mechanisms of action, preclinical and clinical applications, the development and application of CAR-NK cells, and new NK-drug conjugates, also emphasizing that activated NK cells can target and kill highly resistant cancer stem cells. Written by the leading experts on NK immunotherapy worldwide, this is a valuable resource for researchers, clinicians and members of the biomedical field who are interested in understanding novel and efficient therapies to fight cancers.

The internet has become a principal venue for social interaction. Young people are growing up in a world surrounded by technology that could have only been imagined a generation ago. Social media have crafted a landscape that has made connection with others easy. Yet this rise has become a concern. So, what is happening here? Why is it so compelling to use social media? Why is it difficult to quit social media? What impact can social media have on teenagers, their education, and their well-being? Should we be worried? What can be done to help? Psychologist's Guide to Adolescents and Social Media aims to deliver a deeper understanding regarding the psychology of social media, both positive and negative. This guide is divided into four parts. The reader will be guided through the purposes and merits of social media, the unintended consequences of using social media, author conducted research exploring the experiences of adolescent-aged school children, and what can be done to help those struggling with the overuse of social media, including assessment resources.

The brains of males and females, men and women, are different, that is a fact. What is debated is how different and how important are those differences. Sex differences in the brain are determined by genetics, hormones, and experience, which in humans includes culture, society, and parental and peer expectations. The importance of nonbiological variables to sex differences in humans is paramount, making it difficult if not impossible to parse out those contributions that are truly biological. The study of animals provides us the opportunity to understand the magnitude and scope of biologically based sex differences in the brain, and understanding the cellular mechanisms provides us insight into novel sources of brain plasticity. Many sex differences are established during a developmental sensitive window by differences in the hormonal milieu of males versus females. The neonatal testis produces large amounts of testosterone which gains access to the brain and is further metabolized into active androgens and estrogens which modify brain development. Major parameters that are influenced by hormones include neurogenesis, cell death, neurochemical phenotype, axonal and dendritic growth, and synaptogenesis. Variance in these parameters results in sex differences in the size of particular brain regions, the projections between brain regions, and the number and type of synapses within particular brain regions. The cellular mechanisms are both region and endpoint specific and invoke many surprising systems such as prostaglandins, endocannabinoids, and cell death proteins. Epigenetic modifications to the genome both establish and maintain sex differences in the brain and behavior. By understanding when, why, and how sex differences in the brain are established, we may also learn the source of strong gender biases in the relative risk and severity of numerous neurological diseases and disorders of mental health. Boys are much more likely to be diagnosed with autism spectrum or attention and hyperactivity disorders, as well as speech and language deficits, compared to girls. By contrast, women are more likely to suffer from affective disorders, such as depression, anxiety, compulsion, and eating disorders and more likely to experience autoimmune and neurodegenerative disorders. Schizophrenia with an early onset is more common in males but a late-onset version is markedly more frequent in females. Male biased disorders have origins in development while female biased disorders are almost exclusively post-puberty. This remarkable shift in disease risk demands our attention. Novel insights into the biological origins of disease are also gained by comparing and contrasting the same processes in different sexes.

The Oxford Handbook of Metamemory investigates the human ability to evaluate and control learning and information retrieval processes. Each chapter in this authoritative guide highlights a different facet of metamemory research, including classical metamemory judgments; applications of metamemory research to the classroom and courtroom; and cutting-edge perspectives on continuing debates and theory. Chapters also provide broad historical overviews of each research area and discussions of promising directions for future research. The breadth and depth of coverage on offer in this Handbook make it ideal for seminars on metamemory or metacognition. It would also be a valuable supplement for advanced courses on cognitive psychology, of use especially to graduate students and more seasoned researchers who are interested in exploring metamemory for the first time.

This title includes a number of Open Access chapters. This collection presents a broad selection of recent research on analytical chemistry, including methods of determination and analysis as applied to plants, pharmaceuticals, foods, proteins, and more. Analytical chemistry is the study of what chemicals are present and in what amount in natural and artificial materials. Because these understandings are fundamental in just about every chemical inquiry, analytical chemistry is used to obtain information, ensure safety, and solve problems in many different chemical areas, and is essential in both theoretical and applied chemistry. Analytical chemistry is driven by new and improved instrumentation.