Ethical Dimensions of Commercial and DIY Neurotechnologies Volume Three, the latest release in the Developments in Neuroethics and Bioethics series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics surrounding neuroethics and bioethics. Each chapter is written by an international board of authors.

Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and current concepts pertinent to their neurobehavioral genetics. Discussing their natural behavior, motor function, learning and memory, this book focuses on the fry and adult zebrafish, featuring a comprehensive account of modern genetic and neural methods adapted to, or specifically developed for, Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish are presented, as is a section on bioinformatics and "big-data" related questions.

A unique chronology with entries describing the key events in the 3,000-year conflict between religion and science over the explanation and definition of life on Earth. Exhaustively researched and authoritative, Chronology of the Evolution-Creationism Controversy does what no other work does: it examines the conflict between the religious and scientific views of life on Earth in its full 3,000-year historical context, showing readers how this roiling debate has played out over the centuries. With hundreds of entries, Chronology of the Evolution-Creationism Controversy describes specific cultural, religious, and scientific events relevant to the evolution-creationism controversy from the first notions of creationism in ancient Egypt to the present. Within this historical approach, it identifies a number of recurring themes that have shaped the debate through the ages, including famous court cases, the recurrence of the "intelligent design" argument, disagreements over the age of the Earth, and the impact of technological advances on both the scientific and faith-based viewpoints. While approaching the subject globally throughout, the book's second half focuses on tensions between science and religious thought in the United States since the early 1900s. Comprises over 1,400 chronologically arranged entries on important political, legal, and social events in the ongoing controversy between science- and faith-based views of the Earth and life Offers a thorough bibliography spanning historical aspects of the controversy, creationist literature, and resources from evolutionary biology Includes a one-of-a-kind glossary for easy access to definitions of relevant terms used by both anti-evolutionists and scientists Provides an extensive index serving as a reference tool and as a way to explore recurring themes Presents detailed appendices on estimating Earth's age, the geologic timescale, major species of known Hominines, and key legal decisions involving the teaching of evolution and creationism

Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies, Volume Eight, summarizes the molecular mechanisms of drug resistance in colorectal cancer, along with the most up-to-date therapeutic strategies available. The book discusses reasons why colorectal tumors become refractory during the progression of the disease, but also explains how drug resistance occurs during chemotherapy. In addition, users will find the current therapeutic strategies used by clinicians in their practice in treating colorectal cancer. The combination of conventional anticancer drugs with chemotherapy-sensitizing agents plays a pivotal role in improving the outcome of colorectal cancer patients, in particular those with drug-resistant cancer cells. From a clinical point-of-view, the content of this book provides clinicians with updated therapeutic strategies for a better choice of drugs for drug-resistant colorectal cancer patients. It will be a valuable source for cancer researchers, oncologists and several members of biomedical field who are dedicated to better treat patients with colorectal cancer.

There are new and important advancements in todays complexity theories in ICT and requires an extraordinary perspective on the interaction between living systems and information technologies. With human evolution and its continuous link with the development of new tools and environmental changes, technological advancements are paving the way for new evolutionary steps. Complexity Science, Living Systems, and Reflexing Interfaces: New Models and Perspectives is a collection of research provided by academics and scholars aiming to introduce important advancements in areas such as artificial intelligence, evolutionary computation, neural networks, and much more. This scholarly piece will provide contributions that will define the line of development in complexity science.

Repetitive sequences play a major role as a pattern-building device and are a basic syntagmatic linguistic means on all language levels in spoken and signed languages. Little attention has been paid to investigating them in multimodal language use. Do gestures exhibit different types of repetitive sequences? Do they build complex units based on these types and if so, how is the pattern building to be described? How is the interrelation of gestural and spoken units in such complex units? Is it possible to identify repetitive patterns that are comparable to spoken and signed languages and/or patterns specific to the gestural modality? Based on a corpus-analysis of multimodal usage-events, 7 chapters explore gestural repetitions with regard to their structure, semantic and syntactic relevance for multimodal utterances, and cognitive saliency. Fine-grained cognitive-linguistic analyses of multimodal usage events reveal that gestural repetitions are not only a basic principle of building patterns in spoken and signed languages, but also in gestures. By addressing questions of mediality and multimodality of language-in-use, the book contributes to the investigation of repetition as a fundamental means of sign and meaning construction (crosscutting modalities) and enhances the understanding of the multimodal character of language in use.

Secondary Findings in Genomic Research offers a single, highly accessible resource on interpreting, managing and disclosing secondary findings in genomic research. With chapters written by experts in the field, this book is the first to concisely explain the ethical and practical issues raised by secondary genomics findings for a multi and interdisciplinary audience of genomic researchers, translational scientists, clinicians, medical students, genetic counselors, ethicists, legal experts and law students, public policy specialists and regulators. Contributors from Europe, North America, and Asia effectively synthesize perspectives from a spectrum of different scientific, societal, and global contexts, and offer pragmatic approaches to a range of topics, including oversight, governance and policy surrounding secondary genomic results, criteria for identifying results for return, communication and consent, stakeholders' attitudes and perspectives, disclosing results, and clinical, patient-centered protocols.

Mutualisms, interactions between two species that benefit both of them, have long captured the public imagination. Their influence transcends levels of biological organization from cells to populations, communities, and ecosystems. Mutualistic symbioses were crucial to the origin of eukaryotic cells, and perhaps to the invasion of land. Mutualisms occur in every terrestrial and aquatic habitat; indeed, ecologists now believe that almost every species on Earth is involved directly or indirectly in one or more of these interactions. Mutualisms are essential to the reproduction and survival of virtually all organisms, as well as to nutrient cycles in ecosystems. Furthermore, the key ecosystem services that mutualists provide mean that they are increasingly being considered as conservation priorities, ironically at the same time as the acute risks to their ecological and evolutionary persistence are increasingly being identified. This volume, the first general work on mutualism to appear in almost thirty years, provides a detailed and conceptually-oriented overview of the subject. Focusing on a range of ecological and evolutionary aspects over different scales (from individual to ecosystem), the chapters in this book provide expert coverage of our current understanding of mutualism whilst highlighting the most important questions that remain to be answered. In bringing together a diverse team of expert contributors, this novel text captures the excitement of a dynamic field that will help to define its future research agenda.

Authored by world-class scientists and scholars, the Handbook of Natural Resources, Second Edition, is an excellent reference for understanding the consequences of changing natural resources to the degradation of ecological integrity and the sustainability of life. Based on the content of the bestselling and CHOICE awarded Encyclopedia of Natural Resources, this new edition demonstrates the major challenges that the society is facing for the sustainability of all wellbeing on planet Earth. The experience, evidence, methods, and models used in studying natural resources are presented in six stand-alone volumes, arranged along the main systems: land, water, and air. It reviews state-of-the-art knowledge, highlights advances made in different areas, and provides guidance for the appropriate use of remote sensing data in the study of natural resources on a global scale. The six volumes in this set cover: Terrestrial Ecosystems and Biodiversity; Landscape and Land Capacity; Wetlands and Habitats; Fresh Water and Watersheds; Coastal and Marine Environments; and finally Atmosphere and Climate. Written in an easy-to-reference manner, the Handbook of Natural Resources, Second Edition, as a complete set, is essential for anyone looking for a deeper understanding of the science and management of natural resources. Public and private libraries, educational and research institutions, scientists, scholars, and resource managers will benefit enormously from this set. Individual volumes and chapters can also be used in a wide variety of both graduate and undergraduate courses in environmental science and natural science courses at different levels and disciplines, such as biology, geography, Earth system science, ecology, etc.

This volume provides comprehensive information on how mapping an individual's epigenome can be medically relevant and holds the potential to improve preventive medicine and precision therapeutics at an early-stage (prior to disease onset). In order to advance clinical adoption of the recently developed epigenetic approaches, it is necessary for translational scientists, clinicians, and students to gain a better understanding about epigenetic mechanisms that are associated with a particular disorder; and to be able to effectively identify biomarkers that can be applied in drug development and for better diagnosis and prognosis of diseases. Prognostic Epigenetics is the most-inclusive volume to-date specifically dedicated to epigenetic markers that have been developed for prognosis of diseases, recent advances in this field, the clinical implementation of this research, and the future outlook.

The book discusses the complex interactions between plants and their associated microbial communities. It also elucidates the ways in which these microbiomes are connected with the plant system, and how they affect plant health. The different chapters describe how microbiomes affect plants with regard to immunity, disease conditions, stress management and productivity. In addition, the book describes how an 'additional plant genome' functions as a whole organ system of the host, and how it presents both challenges and opportunities for the plant system. Moreover, the book includes a dedicated section on using omics tools to understand these interactions, and on exploiting them to their full potential.

Lymphatic Structure and Function in Health and Disease serves as a resource book on what has been learned about lymphatic structure, function and anatomy within different organ systems. This is the first book to bring together lymphatic medicine as a whole, with in-depth analysis of specific aspects of lymphatics in different vascular pathologies. This book is a useful tool for scientists, practicing clinicians and residents, in particular, those in vascular biology, neurology, cardiology and general medicine. Chapters discuss topics such as ontogeny and phylogeny of lymphatics, lymphatic pumping, CNS lymphatics, lymphatics in transplant and lymphatic reconstruction.

In the tradition of My Stroke of Insight and Brain on Fire, this powerful memoir recounts Barbara Lipska's deadly brain cancer and explains its unforgettable lessons about the brain and mind. Neuroscientist Lipska was diagnosed early in 2015 with metastatic melanoma in her brain's frontal lobe. As the cancer progressed and was treated, she experienced behavioral and cognitive symptoms connected to a range of mental disorders, including dementia and her professional specialty, schizophrenia. Lipska's family and associates were alarmed by the changes in her behavior, which she failed to acknowledge herself. Gradually, after a course of immunotherapy, Lipska returned to normal functioning, amazingly recalled her experience, and through her knowledge of neuroscience identified the ways in which her brain changed during treatment. Lipska admits her condition was unusual; after recovery she was able to return to her research and resume her athletic training and compete in a triathalon. Most patients with similar brain cancers rarely survive to describe their ordeal. Lipska's memoir, coauthored with journalist Elaine McArdle, shows that strength and courage but also an encouraging support network are vital to recovery.