Tissue Engineering Strategies for Organ Regeneration addresses the existing and future trends of tissue engineering approaches for organ/tissue regeneration or repair. This book provides a comprehensive summary of the recent improvement of biomaterials used in scaffold-based tissue engineering, and the tools and different protocols needed to design tissues and organs. The chapters in this book provide the in-depth principles for many of the supporting and enabling technologies including the applications of BioMEMS devices in tissue engineering, and the combination of organoid formation and three dimensional (3D) bioprinting. The book also highlights the advances and strategies for regeneration of three-dimensional microtissues in microcapsules, tissue reconstruction techniques, and injectable composite scaffolds for bone tissue repair and augmentation. Key Features: Addresses the current obstacles to tissue engineering applications Provides the latest improvements in the field of integrated biomaterials and fabrication techniques for scaffold-based tissue engineering Shows the influence of microenvironment towards cell-biomaterials interactions Highlights significant and recent improvements of tissue engineering applications for the artificial organ and tissue generation Describes the applications of microelectronic devices in tissue engineering Describes different current bioprinting technologies

The purpose of this book is to use neuroscience discoveries concerning religious experiences, the Self and personhood to deepen, enhance and interrogate the theological and philosophical set of ideas known as Personalism. McNamara proposes a new eschatological form of personalism that is consistent with current neuroscience models of relevant brain functions concerning the self and personhood and that can meet the catastrophic challenges of the 21st century. Eschatological Personalism, rooted in the philosophical tradition of "Boston Personalism", takes as its starting point the personalist claim that the significance of a self and personality is not fully revealed until it has reached its endpoint, but theologically that end point can only occur within the eschatological realm. That realm is explored in the book along with implications for personalist theory and ethics. Topics covered include the agent intellect, dreams and the imagination, future-orientation and eschatology, phenomenology of Time, social ethics, Love, the challenge of AI, privacy and solitude and the individual ethic of autarchy. This book is an innovative combination of the neuroscientific and theological insights provided by a Personalist viewpoint. As such, it will be of great interest to scholars of Cognitive Science, Theology, Religious Studies and the philosophy of the mind.

Summarizes a complex geological, geographical and ecological history Reviews how the San Diego Bay has changed and will likely change in the future Examines the different roles a various drivers of Bay ecosystem function Includes the role of humans - both first people and modern populations - on the Bay Explores San Diego Bay as an example of general bay ecological and environmental issues

Design of new processes that avoid the use of toxic reagents has been the focus of intense research of late. Catalysis by metals and non-metals offers diverse opportunities for the development of new organic reactions with promising range of selectivities-chemoselectivity, regioselectivity, diastereoselectivity, and enantioselectivity. Furthermore, these transformations frequently occur under mild conditions, tolerate a broad array of functional groups, and proceed with high stereoselectivity. The area of catalysis is sometimes referred to as a 'foundational pillar' of green chemistry. Catalytic reactions often reduce energy requirements and decrease separations because of increased selectivity; they are also capable of permitting the use of renewable feedstocks of less toxic reagents or minimizing the quantities of reagents needed. New catalytic organic synthesis methodologies have, thus, offered several possibilities for considerable improvement in the eco-compatibility of fine chemical production. Hence, these catalytic methodologies have emerged as powerful tools for the efficient and chemoselective synthesis of heterocyclic molecules. Key Features: Presents the synthesis of different five-membered heterocycles. Contains the most up-to-date information in this fast-moving field. Covers novel catalytic approaches used in the study and application of catalysts in synthetic organic reactions. Presents new methodologies for the synthesis of heterocycles.

What lies beneath the surface of the ocean has mystified humankind for millennia. We have explored more of the surface of the Moon than we have of the deep sea. From vampire squid to giant spider crabs, and from hydrothermal vents to bioluminescence, its watery depths are both fascinating and terrifying. Deep Water explores, through spectacular images and expert text, how this unique habitat came into being, what lives there and why, how it has evolved and what the future will bring for this dark and mysterious environment.

Dynamical systems and Nonlinear Waves in Plasmas is written in a clear and comprehensible style to serve as a compact volume for advanced postgraduate students and researchers working in the areas of Applied Physics, Applied Mathematics, Dynamical Systems, Nonlinear waves in Plasmas or other nonlinear media. It provides an introduction to the background of dynamical systems, waves, oscillations and plasmas. Basic concepts of dynamical systems and phase plane analysis for the study of dynamical properties of nonlinear waves in plasmas are presented. Different kinds of waves in plasmas are introduced. Reductive perturbative technique and its applications to derive different kinds of nonlinear evolution equations in plasmas are discussed. Analytical wave solutions of these nonlinear evolution equations are presented using the concept of bifurcation theory of planar dynamical systems in a very simple way. Bifurcations of both small and arbitrary amplitudes of various nonlinear acoustic waves in plasmas are presented using phase plots and time-series plots. Super nonlinear waves and its bifurcation behaviour are discussed for various plasma systems. Multiperiodic, quasiperiodic and chaotic motions of nonlinear plasma waves are discussed in presence of external periodic force. Multistability of plasma waves is investigated. Stable oscillation of plasma waves is also presented in dissipative plasmas. The book is meant for undergraduate and postgraduate students studying plasma physics. It will also serve a reference to the researchers, scientists and faculties to pursue the dynamics of nonlinear waves and its properties in plasmas. It describes the concept of dynamical systems and is useful in understanding exciting features, such as solitary wave, periodic wave, supernonlinear wave, chaotic, quasiperiodic and coexisting structures of nonlinear waves in plasmas. The concepts and approaches, discussed in the book, will also help the students and professionals to study such features in other nonlinear media.

Here is a compilation of the research being done by scientists from various disciplines of chemistry at universities across the globe. This new volume provides a wealth of practical experience and research on new methodologies and important applications in chemical science. It also includes presentations on small-scale new drug design related projects that have potential applications in several disciplines of chemistry and in drug development. In this book, contributions range from new methods to novel applications of existing methods to enhance understanding of the material and/or structural behavior of new and advanced systems. Topics cover computational methods in chemical sciences and electrochemical investigations; studies of some of physico-chemical properties of several important novel macrocyclic ligands; the use of lanthanide-ions doped nanomaterials; quantitative estimation of heavy metals, a sustainable, efficient and green promoter for the synthesis of some heterocyclic compounds; and much more.

* Focuses on human identification using traditional DNA typing methods targeting short tandem repeats (STRs) * Applies the technology and usage to law enforcement investigations and identity and ancestry single nucleotide polymorphisms (SNPs) for investigational leads, mass disaster, and ancestry cases * Introduces the underlying principles of NGS, focusing forensic application and the introduction of NGS into forensic labs in the coming years

Contains the latest developments and technologies from astronomical observatories and telescope facilities on the ground and in space Accompanied by a companion website with examples, tutorials, Python scripts and resources Authored by an observational astronomer with over thirty years of observing and teaching experience

High-k Materials in Multi-Gate FET Devices focuses on high-k materials for advanced FET devices. It discusses emerging challenges in the engineering and applications and considers issues with associated technologies. It covers the various way of utilizing high-k dielectrics in multi-gate FETs for enhancing their performance at the device as well as circuit level. Provides basic knowledge about FET devices Presents the motivation behind multi-gate FETs, including current and future trends in transistor technologies Discusses fabrication and characterization of high-k materials Contains a comprehensive analysis of the impact of high-k dielectrics utilized in the gate-oxide and the gate-sidewall spacers on the GIDL of emerging multi-gate FET architectures Offers detailed application of high-k materials for advanced FET devices Considers future research directions This book is of value to researchers in materials science, electronics engineering, semiconductor device modeling, IT, and related disciplines studying nanodevices such as FinFET and Tunnel FET and device-circuit codesign issues.

The importance of electric arc furnace steelmaking is evident from the escalated world production seen in steel industry. This book presents systematic and complete details on the current state of knowledge about metallurgical processes carried out in the electric arc furnace. It includes principles of construction of electric arc furnaces, applied construction solutions, and their operations (together with auxiliary/supportive devices). Modern technologies of melting of various grades steel are detailed, considering the participation of secondary metallurgy including theoretical backgrounds of chemical processes and reactions. It contains theoretical analysis and results of laboratory, model, and industrial tests. Features: Covers the practical aspects of electric arc furnace steelmaking including technological process. Discusses the operation issues of an electric arc furnace in a technical and technological context. Presents a systematic and complete knowledge about relevant construction solutions and metallurgical processes. Includes practical industrial benchmark indicators in the scope of equipment and technology. Analyses practical case studies from industry. This book aims at researchers, professionals and graduate students in Metallurgical Engineering, Materials Science, Electric Power Supply, Environmental Engineering, and Mechanical Engineering.

As one of the most extensive and important protein post-translational modifications, glycosylation plays a vital role in regulating organisms and is associated with various physiological and pathological processes. Recently, researchers have focused on the need to characterize protein glycosylation sites, structures, and their degree of modification, to better understand their biological functions while also looking for potential biomarkers for diagnosis and treatment of disease. Mass spectrometry (MS) is one of the most powerful tools used to study biomolecules including glycoproteins and glycans. With the continuous development of glycoproteomics and glycomics based on MS analysis, more techniques have evolved and contribute to understanding the structure and function of glycoproteins and glycans. This book reviews advancements achieved in MS-based glycoproteomic analysis, including a wide range of analytical methodologies and strategies involved in selective enrichment; as well as qualitative, quantitative, and data analysis, together with their clinical applications. Significant examples are discussed to illustrate the principles, laboratory protocols, and advice for key implementation to ensure successful results. Mass Spectrometry-Based Glycoproteomics and Its Clinic Application will serve as a valuable resource to elucidate new techniques and their applications for students, postdocs, and researchers working in proteomics, glycoscience, analytical chemistry, biochemistry, and clinical medicine. Editor: Haojie Lu is a professor at Fudan University, specializing in proteomics based on mass spectrometry with particular emphasis on novel technologies for separation and identification of low-abundant proteins and post-translationally modified proteins (including glycosylation), as well as relative and absolute quantification methods for proteomics.

Features Clearly illustrate the mathematical theories of nonlinear systems and its progress to both the non-expert and active researchers in this area Suitable for graduate students in Mathematics, Applied Mathematics and some of the Engineering sciences Written in a careful pedagogical manner by those experts who have been involved in the research themselves, and each contribution is reasonably self-contained

New to the Third Edition New chapter on the Multi-Level Adaptive Cross Approximation (MLACA) New chapter on very large radiation and scattering problems that could not be solved prior to implementing of ACA Thoroughly updated chapter on Fast Multipole Method (FMM), as well as the Multi-Level Fast Multipole Algorithm (MLFMA).

Provides background for design and development of metamaterial structures using novel unit cells. Gives in-depth performance study of miniaturization of microstrip antennas. Discusses design and development of both transmission and reflection types metasurfaces and their practical applications. Verifies a variety of Metamaterial structures and Metasurfaces experimentally

Medicinal Chemistry: A Look at How Drugs Are Discovered is written for those who are interested in learning how drugs are discovered. Compared to other books on the market, this text takes a different approach by presenting the subject on chemical reaction mechanism terms, which ideally makes the subject matter more interesting and easier to comprehend. The authors describe the drug discovery process, from advancing an initial lead to the approval process, and include drug discovery sources. Additional features: Explains medicinal chemistry on chemical mechanism terms, allowing for a more interesting and easier to comprehend text Includes valuable insights toward the various pathways taken at pharmaceutical industries in drug discoveries Improved by including questions raised and suggestions made from students in the authors' medicinal chemistry classes This book will benefit both upper level undergraduates and graduates studying in the fields of medicinal chemistry and drug discovery, as well as scientists working in the pharmaceutical industry.

Reversibility of Chronic Disease and Hypersensitivity, Volume 4: The Environmental Aspects of Chemical Sensitivity is the fourth of an encyclopedic five-volume set describing the basic physiology, chemical sensitivity, diagnosis, and treatment of chronic degenerative disease studied in a 5x less polluted controlled environment. This text focuses on treatment techniques, strategies, protocols, prescriptions, and technologies. Distinguishing itself from previous works on chemical sensitivity, it explains newly understood mechanisms of chronic disease and hypersensitivity, involving core molecular function. The authors discuss new information on ground regulation system, genetics, the autonomic nervous system, and immune and non-immune functions. The book also includes the latest technology and cutting-edge techniques, numerous figures, and supporting research.

Describes extensively the design and microfabrication of nanosensors based on nanotechnological tools. Provides a wide range of bioplatforms based on e.g., carbon nanostructures and Describes extensively a large number of application as a part of Nanomaterial based biosensors.

1) Classic anatomical atlases 2) Detailed labeling of the earliest phases of prenatal neurological development 3) Appeals to neuroanatomists, developmental biologists and clinical practitioners. 4) Persistent relevance - brain development is not going to change

Throughout his remarkable career, Donald Pfaff has demonstrated that by choosing problems and methods with care, biologists can study the molecular mechanisms of brains more complex than those of fruit flies, snails, roundworms, and other invertebrates. His half century in the lab, starting with his discovery of hormone receptors in the brains of mammals and leading to the first detailed account of a neural circuit for mammalian behavior, puts him in a unique position to survey the origins and development of behavioral neurobiology and the current state of research. How the Vertebrate Brain Regulates Behavior offers a close-up, conversational perspective on scientific struggles and successes throughout a fifty-year quest to understand how behavior is regulated in a complex organism. In graduate school, when Pfaff expressed a desire to study behavioral regulation, his advisor suggested focusing on hormones. Pfaff's investigation into the hormonal basis of female sexual behavior in laboratory rats led him to a comprehensive appreciation of how hormone-dependent neurons work through neural circuits to produce discrete behaviors among all vertebrates. This breakthrough, along with other researchers' findings, established a link between molecular biology and neuroscience that opened up a fruitful new field of inquiry. Pfaff's approach is to focus on one solvable problem and explore it from many angles. He begins with a single observed behavior and traces its regulation through a series of biological mechanisms-from hormones to genes to neural circuits. Pfaff's relentless pursuit of his goals continues to inspire neuroscientists today.

Management in the Age of Digital Business Complexity focuses on how the digital age is changing management and vastly speeding up complexity dynamics. The recent coevolution of technologies has dramatically changed in just a few years how people and firms learn, communicate, and behave. Consequently, the process of how firms coevolve and the speed at which they coevolve has been dramatically changed in the digital age, and managerial methods are lagging way behind. Combining his own expertise with that of a number of specialist and international co-authors, McKelvey conveys how companies that fall behind digitally can quickly be driven out of business. The book has been created for academics seeking to upgrade management thinking into the modern digital age and vastly improve the change capabilities of firms facing digital-oriented competition.

This book offers a unique balance between a basic introductory knowledge of bioinformatics and a detailed study of algorithmic techniques. Bioinformatics and RNA: A Practice-Based Approach is a complete guide on the fundamental concepts, applications, algorithms, protocols, new trends, challenges, and research results in the area of bioinformatics and RNA. The book offers a broad introduction to the explosively growing new discipline of bioinformatics. It covers theoretical topics along with computational algorithms. It explores RNA bioinformatics, which contribute to therapeutics and drug discovery. Implementation of algorithms in a DotNet Framework with code and complete insight on the state-of-the-art and recent advancements are presented in detail. The book targets both novice readers as well as practitioners in the field. FEATURES Offers a broad introduction to the explosively growing new discipline of bioinformatics Covers theoretical topics and computational algorithms Explores RNA bioinformatics to unleash the potential from therapeutics to drug discovery Discusses implementation of algorithms in DotNet Frameworks with code Presents insights into the state of the art and recent advancements in bioinformatics The book is useful to undergraduate students with engineering, science, mathematics, or biology backgrounds. Researchers will be equally interested.

Provides an understanding of (mostly) enzymatic reactions that are responsible for the function and maintenance of living things This innovative text for non-biochemistry majors includes introductory material at the beginning of each chapter that contextualizes chapter themes in real-life scenarios Online supporting materials with further opportunities for research and investigation Synthesis questions at the end of each chapter that encourage students to make connections between concepts and ideas, as well as develop critical-thinking skills

Focuses on blow room sequence of machines and its functioning. Discusses role of electronics in management of various controls. Reviews practical perspective of modern techniques used in processing cotton through blow room. Offers an exclusive chapter on modern blow room concept. Includes solved examples and exercises.