Features Provides a comprehensive review of all aspects of skin cancer management. Edited by experts in the area, with interdisciplinary and international collaborators. Promotes a 'Bigger picture' approach to the topic with multidisciplinary insight.

External-beam radiotherapy has long been challenged by the simple fact that patients can (and do) move during the delivery of radiation. Recent advances in imaging and beam delivery technologies have made the solution-adapting delivery to natural movement-a practical reality. Adaptive Motion Compensation in Radiotherapy provides the first detailed treatment of online interventional techniques for motion compensation radiotherapy. This authoritative book discusses: Each of the contributing elements of a motion-adaptive system, including target detection and tracking, beam adaptation, and patient realignment Treatment planning issues that arise when the patient and internal target are mobile Integrated motion-adaptive systems in clinical use or at advanced stages of development System control functions essential to any therapy device operating in a near-autonomous manner with limited human interaction Necessary motion-detection methodology, repositioning techniques, and approaches to interpreting and responding to target movement data in real time Medical therapy with external beams of radiation began as a two-dimensional technology in a three-dimensional world. However, in all but a limited number of scenarios, movement introduces the fourth dimension of time to the treatment problem. Motion-adaptive radiation therapy represents a truly four-dimensional solution to an inherently four-dimensional problem. From these chapters, readers will gain not only an understanding of the technical aspects and capabilities of motion adaptation but also practical clinical insights into planning and carrying out various types of motion-adaptive radiotherapy treatment.

Edited by a renowned international expert in the field, Nuclear Medicine Physics offers an up-to-date, state-of-the-art account of the physics behind the theoretical foundation and applications of nuclear medicine. It covers important physical aspects of the methods and instruments involved in modern nuclear medicine, along with related biological topics. The book first discusses the physics of and machines for producing radioisotopes suitable for use in conventional nuclear medicine and PET. After focusing on positron physics and the applications of positrons in medicine and biology, it describes the use of radiopharmaceuticals in molecular imaging, clinical, and research studies. The text then covers modern radiation detectors and measuring methods, including those used in nuclear imaging, as well as numerous imaging methodologies and models, such as two- and three-dimensional image reconstruction algorithms, data processing sequences, new nuclear oncology techniques, and physiological models of the central nervous system. It also introduces biological systems theory, nuclear medicine methods as systems theory procedures, and aspects of kinetic modeling. The final chapter explores dosimetry and the biological effects of ionizing radiation. With many new developments occurring in nuclear medicine, it is important to understand how advanced approaches are being used in emerging applications. Offering invaluable insight into this growth, Nuclear Medicine Physics provides in-depth descriptions of new radiolabeled biological drugs, new cell labeling techniques, new technical concepts in radiation detection, improvements in instrumentation, and much more.

This book contains contributions from computational biomechanics specialists who present and exchange opinions on the opportunities for applying their techniques to computer-integrated medicine, including computer-aided surgery and diagnostic systems. Computational Biomechanics for Medicine collects peer-reviewed chapters from the annual Computational Biomechanics for Medicine Workshop, in conjunction with the Medical Image Computing and Computer Assisted Intervention [MICCAI] Society conference. The works are dedicated to research in the field of methods and applications of computational biomechanics to medical image analysis, image-guided surgery, surgical simulation, surgical intervention planning, disease diagnosis and prognosis, analysis of injury mechanisms, implant and prosthesis design, artificial organ design, and medical robotics. These chapters will appeal to a wide range of researchers and students within the fields of engineering and medicine, as well as those working in computational science.

Readable and concise - focusing on the common diseases that medical students most frequently encounter Fully revised and updated - including up to date information on the latest imaging techniques including spectral CT, liver elastography, new and emerging PET techniques, multiparametric imaging and the role of AI Heavily illustrated - over 450 high-quality photographs, many new to this edition including colour images, are essential to support this visual subject Highly structured and accessible format - plentiful use of tables and lists, and introduction of new summary boxes, all ideal for study and exam preparation Companion website - image library including normal anatomy, clinical cases and MCQs for self-assessment, RADS reporting systems and detailed staging systems for common tumours relevant to each section; visit www.routledge.com/cw/hacking Drawing on the extensive clinical and teaching experience of its respected author team, the fifth edition of Imaging for Students gives students and junior doctors everything they need to understand the advantages, disadvantages, and possible side effects of the imaging modalities available, and how to apply them appropriately in clinical practice.

This book provides a first authoritative text on radiochromic film, covering the basic principles, technology advances, practical methods, and applications. It focuses on practical uses of radiochromic film in radiation dosimetry for diagnostic x-rays, brachytherapy, radiosurgery, external beam therapies (photon, electron, protons), stereotactic body radiotherapy, intensity-modulated radiotherapy, and other emerging radiation technologies. The expert authors address basic concepts, advantages, and the main applications including kilovoltage, brachytherapy, megavoltage, electron beam, proton beam, skin dose, in vivo dosimetry, postal and clinical trial dosimetry. The final chapters discuss the state of the art in microbeam, synchrotron radiation, and ultraviolet radiation dosimetry.

This first dedicated overview for beam's eye view (BEV) covers instrumentation, methods, and clinical use of this exciting technology, which enables real-time anatomical imaging. It highlights how the information collected (e.g., the shape and size of the beam aperture and intensity of the beam) is used in the clinic for treatment verification, adaptive radiotherapy, and in-treatment interventions. The chapters cover detector construction and components, common imaging procedures, and state of the art applications. The reader will also be presented with emerging innovations, including target modifications, real-time tracking, reconstructing delivered dose, and in vivo portal dosimetry. Ross I. Berbeco, PhD, is a board-certified medical physicist and Associate Professor of Radiation Oncology at the Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School.

This book provides a first comprehensive summary of the basic principles, instrumentation, methods, and clinical applications of three-dimensional dosimetry in modern radiation therapy treatment. The presentation reflects the major growth in the field as a result of the widespread use of more sophisticated radiotherapy approaches such as intensity-modulated radiation therapy and proton therapy, which require new 3D dosimetric techniques to determine very accurately the dose distribution. It is intended as an essential guide for those involved in the design and implementation of new treatment technology and its application in advanced radiation therapy, and will enable these readers to select the most suitable equipment and methods for their application. Chapters include numerical data, examples, and case studies.

Implement TMR with Your Patients and Improve Their Quality of Life Developed by Dr. Todd A. Kuiken and Dr. Gregory A. Dumanian, targeted muscle reinnervation (TMR) is a new approach to accessing motor control signals from peripheral nerves after amputation and providing sensory feedback to prosthesis users. This practical approach has many advantages over other neural-machine interfaces for the improved control of artificial limbs. Targeted Muscle Reinnervation: A Neural Interface for Artificial Limbs provides a template for the clinical implementation of TMR and a resource for further research in this new area of science. After describing the basic scientific concepts and key principles underlying TMR, the book presents surgical approaches to transhumeral and shoulder disarticulation amputations. It explores the possible role of TMR in the prevention and treatment of end-neuromas and details the principles of rehabilitation, prosthetic fitting, and occupational therapy for TMR patients. The book also describes transfer sensation and discusses the surgical and functional outcomes of the first several TMR patients. It concludes with emerging research on using TMR to further improve the function and quality of life for people with limb loss. With contributions from renowned leaders in the field, including Drs. Kuiken and Dumanian, this book is a useful guide to implementing TMR in patients with high-level upper limb amputations. It also supplies the foundation to enable improvements in TMR techniques and advances in prosthetic technology.

This three-volume set explores Problems and Solutions in Medical Physics. These invaluable study guides should be used in conjunction with other key textbooks in the field to provide additional learning opportunities. Volume one explores Diagnostic Imaging Physics and contains problems and solutions on key imaging modalities, exploring X-ray, mammography, and fluoroscopy, in addition to computed tomography, magnetic resonance imaging, and ultrasonography. Volume two explores Nuclear Medicine and contains problems and solutions on radioactivity and nuclear transformation, radionuclide production and radiopharmaceuticals, non-imaging detectors and counters, instrumentation for gamma imaging, SPECT and PET/CT, imaging techniques, radionuclide therapy, internal radiation dosimetry, and quality control and radiation protection in nuclear medicine. Volume three explores Radiotherapy and contains problems and solutions on external beam therapy equipment, photon beam physics, radiation dosimetry, treatment planning for external beam radiotherapy, and external beam commissioning and quality assurance. Each chapter provides examples, notes, and references for further reading to enhance understanding. Features: Consolidates concepts and assists in the understanding and applications of theoretical concepts in medical physics Assists lecturers and instructors in setting assignments and tests Suitable as a revision tool for postgraduate students sitting medical physics, oncology, and radiology sciences examinations

The book has two intentions. First, it assembles the latest research in the field of medical imaging technology in one place. Detailed descriptions of current state-of-the-art medical imaging systems (comprised of x-ray CT, MRI, ultrasound, and nuclear medicine) and data processing techniques are discussed. Information is provided that will give interested engineers and scientists a solid foundation from which to build with additional resources. Secondly, it exposes the reader to myriad applications that medical imaging technology has enabled.

The evolution of technological advances in infrared sensor technology, image processing, "smart" algorithms, knowledge-based databases, and their overall system integration has resulted in new methods of research and use in medical infrared imaging. The development of infrared cameras with focal plane arrays no longer requiring cooling, added a new dimension to this modality. Medical Infrared Imaging: Principles and Practices covers new ideas, concepts, and technologies along with historical background and clinical applications. The book begins by exploring worldwide advances in the medical applications of thermal imaging systems. It covers technology and hardware including detectors, detector materials, un-cooled focal plane arrays, high performance systems, camera characterization, electronics for on-chip image processing, optics, and cost-reduction designs. It then discusses the physiological basis of the thermal signature and its interpretation in a medical setting. The book also covers novel and emerging techniques, the complexities and importance of protocols for effective and reproducible results, storage and retrieval of thermal images, and ethical obligations. Of interest to both the medical and biomedical engineering communities, the book explores many opportunities for developing and conducting multidisciplinary research in many areas of medical infrared imaging. These range from clinical quantification to intelligent image processing for enhancement of the interpretation of images, and for further development of user-friendly high-resolution thermal cameras. These would enable the wide use of infrared imaging as a viable, noninvasive, low-cost, first-line detection modality.

Based on hospital clinical trials examining the use of signal and image processing techniques, Surface Imaging for Biomedical Applications bridges the gap between engineers and clinicians. This text offers a thorough analysis of biomedical surface imaging to medical practitioners as it relates to the diagnosis, detection, and monitoring of skin conditions and disease. Written from an engineer's perspective, the book discusses image acquisition methods, image processing, and pattern recognition techniques. It focuses on a variety of techniques used in recent years for image processing and pattern recognition (principal component analysis, independent component analysis, singular value decomposition, texture modeling, inverse model analysis, polynomial surface fitting, and classification techniques), and considers interventional and non-invasive procedures used to diagnose skin-related disease. It examines the biological causation of four skin disorders (psoriasis, vitiligo, ulcer, and acne), provides basic terminologies in surface imaging, and details the outcome of various clinical observations and other research. It also details numerous measurement parameters related to surface imaging (body surface, skin color, tissue characteristic, thickness, roughness, volume of skin, and retinal changes). Discusses the development of a psoriasis severity measurement tool Provides material on assessing segmented repigmentation areas in vitiligo patients via VT-Scan Introduces a volume ulcer assessment using non-invasive 3D imaging Presents an automated system for acne grading that is based on capturing the images of various body parts using the DSLR camera Includes the MATLAB (R) codes for various pattern recognition techniques applied during the assessment/measurement at the end of each chapter This interdisciplinary reference highlights the importance of disease diagnosis and monitoring, and is suitable for medical practitioners, biomedical engineers, and core image processing researchers.

This three-volume set explores Problems and Solutions in Medical Physics. These invaluable study guides should be used in conjunction with other key textbooks in the field to provide additional learning opportunities. Volume one explores Diagnostic Imaging Physics and contains problems and solutions on key imaging modalities, exploring X-ray, mammography, and fluoroscopy, in addition to computed tomography, magnetic resonance imaging, and ultrasonography. Volume two explores Nuclear Medicine and contains problems and solutions on radioactivity and nuclear transformation, radionuclide production and radiopharmaceuticals, non-imaging detectors and counters, instrumentation for gamma imaging, SPECT and PET/CT, imaging techniques, radionuclide therapy, internal radiation dosimetry, and quality control and radiation protection in nuclear medicine. Volume three explores Radiotherapy and contains problems and solutions on external beam therapy equipment, photon beam physics, radiation dosimetry, treatment planning for external beam radiotherapy, and external beam commissioning and quality assurance. Each chapter provides examples, notes, and references for further reading to enhance understanding. Features: Consolidates concepts and assists in the understanding and applications of theoretical concepts in medical physics Assists lecturers and instructors in setting assignments and tests Suitable as a revision tool for postgraduate students sitting medical physics, oncology, and radiology sciences examinations

Authored by a leading educator, this book teaches the fundamental mathematics and physics concepts associated with medical imaging systems. Going beyond mere description of imaging modalities, this book delves into the mechanisms of image formation and image quality common to all imaging systems: contrast mechanisms, noise, and spatial and temporal resolution, making it an important reference for medical physicists and biomedical engineering students. This is an extensively revised new edition of The Physics of Medical X-Ray Imaging by Bruce Hasegawa (Medical Physics Publishing, 1991), and includes a wide range of modalities such as X-ray CT, MRI and SPECT.

The workshop "Biologically Inspired Physics" was organized, with the support of the NATO Scientific Affairs Division and the Directorate-General for Science, Research and Development of the Commission of the European Communities, in order to review some subjects of physics of condensed matter which are inspired by biological problems or deal with biological systems, but which address physical questions. The main topics discussed in the meeting were: 1. Macromolecules: In particular, proteins and nucleic acids. Special emphasis was placed on modelling protein folding, where analogies with disordered systems in con densed matter (glasses, spin glasses) were suggested. It is not clear at this point whether such analogies will help in solving the folding problem. Interesting problems in nucleic acids (in particular DNA) deal with the dynamics of semiflexible chains with torsion and the relationship between topology and local structure. They arise from such biological problems as DNA packing or supercoiling. 2. Membranes: This field has witnessed recent progress in the understanding of the statistical mechanics of fluctuating flexible sheets, such as lipid bilayers. It appears that one is close to understanding shape fluctuations in red blood cells on a molec ular basis. Open problems arise from phenomena such as budding or membrane fusion. Experiments on model systems, such as vesicle systems or artificial lipids, have great potential. Phenomena occurring inside the membrane (protein diffusion, ionic pumps) were only discussed briefly."

This state-of-the-art set of handbooks provides medical physicists with a comprehensive overview of the field of nuclear medicine. In addition to describing the underlying, fundamental theories of the field, it includes the latest research and explores the practical procedures, equipment, and regulations that are shaping the field and it's future. This set is split into three volumes, respectively titled: Instrumentation and Imaging Procedures; Modelling, Dosimetry and Radiation Protection; and Radiopharmaceuticals and Clinical Applications. Volume one, Instrumentation and Imaging Procedures, focuses primarily on providing a comprehensive review into the detection of radiation, beginning with an introduction to the history of nuclear medicine to the latest imaging technology. Volume two, Modelling, Dosimetry and Radiation Protection, explores the applications of mathematical modelling, dosimetry, and radiation protection in nuclear medicine. The third and final volume, Radiopharmaceuticals and Clinical Applications, highlights the production and application of radiopharmaceuticals and their role in clinical nuclear medicine practice. These books will be an invaluable resource for libraries, institutions, and clinical and academic medical physicists searching for a complete account of what defines nuclear medicine. The most comprehensive reference available providing a state-of-the-art overview of the field of nuclear medicine Edited by a leader in the field, with contributions from a team of experienced medical physicists, chemists, engineers, scientists, and clinical medical personnel Includes the latest practical research in the field, in addition to explaining fundamental theory and the field's history

Medical practitioners, scientists and graduate students alike will find this exhaustive survey a vital learning tool. It provides a thorough description of the fundamentals and applications in the field of laser-tissue interactions. Basic concepts such as the optical and thermal properties of tissue, the various types of tissue ablation, and optical breakdown and its related effects are treated in detail. The author pays special attention to mathematical tools (Monte Carlo simulations, the Kubelka-Munk theory etc.) and approved techniques (photodynamic therapy, laser-induced interstitial thermotherapy etc.). A section on applications reviews clinically relevant methods in modern medicine using the latest references.

Researchers from North America, eastern and western Europe, and the Soviet Union contribute 45 papers relating mathematical and experimental results on nonlinear wave phenomena in excitable media and related nonlinear systems. A nonlinear sampling of topics reveals such findings as sustained reactio

- All of the contributors are renowned experts in the field, and many are pioneers of radiosurgery (such as L. Dade Lunsford, Douglas Kondziolka, Jason Sheehan, Jean Regis).

Experienced Guidance on the Technical Issues of Decommissioning ProjectsWritten by one of the original MARSSIM authors, Decommissioning Health Physics: A Handbook for MARSSIM Users, Second Edition is the only book to incorporate all of the requisite technical aspects of planning and executing radiological surveys in support of decommissioning. Extensively revised and updated, it covers survey instrumentation, detection sensitivity, statistics, dose modeling, survey procedures, and release criteria. New to the Second Edition Chapter on hot spot assessment that recognizes appropriate dosimetric significance of hot spots when designing surveys and includes a new approach for establishing hot spot limits Chapter on the clearance or release of materials, highlighting aspects of the MARSAME manual Revised chapter on characterization survey design to reflect guidance in ANSI N13.59 on the value of data quality objectives (DQOs) Updated regulations and guidance documents throughout Updated survey instrumentation used to support decontamination and decommissioning (D&D) surveys, including expanded coverage of in situ gamma spectrometers Revised statistics chapter that includes an introduction to Bayesian statistics and additional double sampling and ranked set sampling statistical approaches More case studies and examples throughout Implement the Surveys Effectively and Avoid Common PitfallsWith more than 20 years of experience as a practitioner in the decommissioning survey field, author Eric W. Abelquist prepares you for the technical challenges associated with planning and executing MARSSIM surveys. He discusses the application of statistics for survey design and data reduction and addresses the selection of survey instrumentation and detection sensitivity. He presents final status survey procedures and covers pathway modeling to translate release criteria to measurable quantities. He also offers solutions for navigating the complexity inherent in designing and implementing MARSSIM and MARSAME surveys. Detailed derivations, thorough discussions of technical bases, and real-world examples and case studies illustrate effective strategies for demonstrating to regulators and stakeholders that contaminated sites can be released for other beneficial uses.

Targets both students or professionals, both novice and experienced, in medical radiotherapy physics. Combines overviews of development, methods and references to facilitate Monte Carlo studies. Focuses on applications in radiotherapy.

Targets both students or professionals, both novice and experienced, in medical radiotherapy physics. Combines overviews of development, methods and references to facilitate Monte Carlo studies. Focuses on applications in radiotherapy.

Contains over 3300 entries with accompanying diagrams, images, formulas, further reading, and examples Covers both the classical and newest elements in medical imaging, radiotherapy, and radiation protection Discusses material at a level accessible to graduate and postgraduate students in medical physics and related disciplines as well as medical specialists and researchers.