The Physics of Three Dimensional Radiation Therapy presents a broad study of the use of three-dimensional techniques in radiation therapy. These techniques are used to specify the target volume precisely and deliver radiation with precision to minimize damage to surrounding healthy tissue. The book discusses multimodality computed tomography, complex treatment planning software, advanced collimation techniques, proton radiotherapy, megavoltage imaging, and stereotactic radiosurgery. A review of the literature, numerous questions, and many illustrations make this book suitable for teaching a course. The themes covered in this book are developed and expanded in Webb's The Physics of Conformal Radiotherapy and the two may be used together or in successive semesters for teaching purposes.

The Topics Every Medical Physicist Should Know Tutorials in Radiotherapy Physics: Advanced Topics with Problems and Solutions covers selected advanced topics that are not thoroughly discussed in any of the standard medical physics texts. The book brings together material from a large variety of sources, avoiding the need for you to search through and digest the vast research literature. The topics are mathematically developed from first principles using consistent notation. Clear Derivations and In-Depth Explanations The book offers insight into the physics of electron acceleration in linear accelerators and presents an introduction to the study of proton therapy. It then describes the predominant method of clinical photon dose computation: convolution and superposition dose calculation algorithms. It also discusses the Boltzmann transport equation, a potentially fast and accurate method of dose calculation that is an alternative to the Monte Carlo method. This discussion considers Fermi Eyges theory, which is widely used for electron dose calculations. The book concludes with a step-by-step mathematical development of tumor control and normal tissue complication probability models. Each chapter includes problems with solutions given in the back of the book. Prepares You to Explore Cutting-Edge Research This guide provides you with the foundation to read review articles on the topics. It can be used for self-study, in graduate medical physics and physics residency programs, or in vendor training for linacs and treatment planning systems.

Prepare for success on the ARRT exam and in the practice of radiography! Essentials of Radiographic Physics and Imaging, 3rd Edition follows the ASRT recommended curriculum and focuses on what the radiographer needs to understand to safely and competently perform radiographic examinations. This comprehensive text gives you a foundational understanding of basic physics principles such as atom structure, electricity and magnetism, and electromagnetic radiation. It then covers imaging principles, radiation production and characteristics, digital image quality, imaging equipment, digital image acquisition and display, image analysis, and more- linking physics to the daily practice of radiographers. New for the third edition is updated information on radiation classifications, a shift in focus to SI units, and a thoroughly updated chapter on Fluoroscopic Imaging. UPDATED! Content reflects the newest standards outlined by the ARRT and ASRT, providing you with the information you needed to pass the boards. Chapter Review Questions at the end of every chapter allow you to evaluate how well you have mastered the material in each chapter. Critical Thinking Questions at the end of every chapter offer opportunity for review and greater challenge. Critical Concept boxes further explain and emphasize key points in the chapters. Radiation Protection callout boxes help you understand the ethical obligations to minimize radiation dosages, shielding, time and distance, how to limit the field of exposure and what that does to minimize dose, and technical factors and how they affect the primary beam and image quality. More than 400 photos and line drawings encourage you to visualize important concepts. Strong pedagogy, including chapter objectives, key terms, outlines, bulleted chapter summaries, and specialty boxes, help you to organize information and focus on what is most important in each chapter. An emphasis on the practical information highlights just what you need to know to ace the ARRT exam and become a competent practitioner. Numerous critique exercises teach you how to evaluate the quality of radiographic images and determine which factors produce poor images. NEW! A shift in focus to SI units aligns with international system of measurement. UPDATED Information regarding radiation classifications helps you to understand radiation levels. NEW! Inclusion of advances in digital imaging helps familiarize you with state-of-the-art images. NEW and UPDATED! Expanded Digital Fluoroscopy chapter, familiarizes you with the equipment you will encounter.

Through a biophysical approach, Electromagnetic Fields in Biology and Medicine provides state-of-the-art knowledge on both the biological and therapeutic effects of Electromagnetic Fields (EMFs). The reader is guided through explanations of general problems related to the benefits and hazards of EMFs, step-by-step engineering processes, and basic results obtained from laboratory and clinical trials. Basic biological mechanisms reviewed by several authors lead to an understanding of the effects of EMFs on microcirculation as well as on immune and anti-inflammatory responses. Based upon investigational mechanisms for achieving potential health benefits, various EMF medical applications used around the world are presented. These include the frequent use of EMFs in wound healing and cartilage/bone repair as well as use of EMFs in pain control and inhibition of cancer growth. Final chapters cover the potential of using the novel biophysical methods of electroporation and nanoelectroporation in electrochemotherapy, gene therapy, and nonthermal ablation. Also covered is the treatment of tendon injuries in animals and humans. This book is an invaluable tool for scientists, clinicians, and medical and engineering students.

CMOS: Front-End Electronics for Radiation Sensors offers a comprehensive introduction to integrated front-end electronics for radiation detectors, focusing on devices that capture individual particles or photons and are used in nuclear and high energy physics, space instrumentation, medical physics, homeland security, and related fields. Emphasizing practical design and implementation, this book: Covers the fundamental principles of signal processing for radiation detectors Discusses the relevant analog building blocks used in the front-end electronics Employs systematically weak and moderate inversion regimes in circuit analysis Makes complex topics such as noise and circuit-weighting functions more accessible Includes numerical examples where appropriate CMOS: Front-End Electronics for Radiation Sensors provides specialized knowledge previously obtained only through the study of multiple technical and scientific papers. It is an ideal text for students of physics and electronics engineering, as well as a useful reference for experienced practitioners.

The proposed book aims to explain the basic principles, concepts and regulations behind radiation protection and their application in the field of radiation oncology practice. This book will be useful to all those students, teachers and practicing professionals involved in the field of radiation oncology.

This book introduces advanced and hybrid compression techniques specifically used for medical images. The book discusses conventional compression and compressive sensing (CS) theory based approaches that are designed and implemented using various image transforms, such as: Discrete Fourier Transform (DFT), Discrete Cosine Transform (DCT), Discrete Wavelet Transform (DWT), and Singular Value Decomposition (SVD) and greedy based recovery algorithm. The authors show how these techniques provide simulation results of various compression techniques for different types of medical images, such as MRI, CT, US, and x-ray images. Future research directions are provided for medical imaging science. The book will be a welcomed reference for engineers, clinicians, and research students working with medical image compression in the biomedical imaging field. Covers various algorithms for data compression and medical image compression; Provides simulation results of compression algorithms for different types of medical images; Provides study of compressive sensing theory for compression of medical images.

Written by internationally known experts in the field, Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy examines one of the fastest-developing subspecialties within radiation oncology. These procedures deliver large doses of radiation in one to five sessions to a precisely determined target. Often these techniques have proven to be as or more effective than traditional radiation therapy techniques, while at the same time being cost-efficient and convenient for the patient. These techniques, however, require careful planning, specialized equipment, and well-trained staff. This volume provides a cutting-edge look at the biological and technical underpinnings of SRS and SBRT techniques. It includes a history of the development of SRS and SBRT; clinical applications of the techniques; dedicated devices for delivering precisely shaped, high doses of radiation; use of in-room imaging for treatment planning and treatment guidance; immobilization techniques for accurate targeting; and future developments that will continue to evolve and refine existing techniques. A valuable introduction to those just learning about these specialized techniques, and an ideal reference for those who are already implementing them, this book covers a wide variety of topics, with clear discussions of each aspect of the technology employed.

Modern brachytherapy is one of the most important oncological treatment modalities requiring an integrated approach that utilizes new technologies, advanced clinical imaging facilities, and a thorough understanding of the radiobiological effects on different tissues, the principles of physics, dosimetry techniques and protocols, and clinical expertise. A complete overview of the field, Comprehensive Brachytherapy: Physical and Clinical Aspects is a landmark publication, presenting a detailed account of the underlying physics, design, and implementation of the techniques, along with practical guidance for practitioners. Bridging the gap between research and application, this single source brings together the technological basis, radiation dosimetry, quality assurance, and fundamentals of brachytherapy. In addition, it presents discussion of the most recent clinical practice in brachytherapy including prostate, gynecology, breast, and other clinical treatment sites. Along with exploring new clinical protocols, it discusses major advances in imaging, robotics, dosimetry, Monte Carlo-based dose calculation, and optimization.

The Topics Every Medical Physicist Should Know Tutorials in Radiotherapy Physics: Advanced Topics with Problems and Solutions covers selected advanced topics that are not thoroughly discussed in any of the standard medical physics texts. The book brings together material from a large variety of sources, avoiding the need for you to search through and digest the vast research literature. The topics are mathematically developed from first principles using consistent notation. Clear Derivations and In-Depth Explanations The book offers insight into the physics of electron acceleration in linear accelerators and presents an introduction to the study of proton therapy. It then describes the predominant method of clinical photon dose computation: convolution and superposition dose calculation algorithms. It also discusses the Boltzmann transport equation, a potentially fast and accurate method of dose calculation that is an alternative to the Monte Carlo method. This discussion considers Fermi-Eyges theory, which is widely used for electron dose calculations. The book concludes with a step-by-step mathematical development of tumor control and normal tissue complication probability models. Each chapter includes problems with solutions given in the back of the book. Prepares You to Explore Cutting-Edge Research This guide provides you with the foundation to read review articles on the topics. It can be used for self-study, in graduate medical physics and physics residency programs, or in vendor training for linacs and treatment planning systems.

* Chapters describe the impact of our reliance plastics in certain sectors and how they relate to microplastic pollution * Investigates emerging solutions to the microplastic pollution * Presents a multi-disciplinary perspective, covering topics such as analytical techniques, quantitative techniques, environmental monitoring and human health monitoring

The application of radiation to medical problems plays an ever-increasing role in diagnosis and treatment of disease. It is essential that medical physicists have the knowledge, understanding and practical skills to implement radiation protection as new techniques are developed. Practical Radiation Protection in Healthcare provides a practical guide for medical physicists and others involved with radiation protection in the healthcare environment. The guidance is based on principles set out in current recommendations of the International Commission for Radiological Protection and methods developed by a variety of professional bodies. Written by practitioners experienced in the field this practical reference manual covers both established techniques and new areas of application. This new edition has be fully revised and updated to cover new requirements linked to the increased knowledge of radiation effects, and the development of new technology. Each specialist area is covered in a separate chapter to allow easy reference with individual chapters being assigned to different types of non-ionising radiations. Tabulated data is included to allow the reader to carry out calculations for situations encountered frequently without reference to further texts.

This popular text provides a comprehensive, yet accessible, introduction to the physics and technology of medical ultrasound, with high quality ultrasound images and diagrams throughout. Covering all aspects of the field at a level that meetings the requirements of accredited sonography courses, it is ideal for both trainee and qualified healthcare professionals practising ultrasound in a clinical setting. Building on the content of previous editions, this third edition provides the latest guidance relating to ultrasound technology, quality assurance and safety and discusses the latest techniques.

Cardiovascular and Neurovascular Imaging: Physics and Technology explains the underlying physical and technical principles behind a range of cardiovascular and neurovascular imaging modalities, including radiography, nuclear medicine, ultrasound, and magnetic resonance imaging (MRI). Examining this interdisciplinary branch of medical imaging from academic, clinical, and industrial perspectives, this comprehensive book: Covers each major imaging modality as well as special applications, time-resolved techniques, and image-guided therapies Discusses image quality and accuracy, radiation safety and dosimetry, and image formation and analysis Explores current and future trends in vascular imaging procedures and technologies Featuring chapters authored by field experts, Cardiovascular and Neurovascular Imaging: Physics and Technology combines the latest information on the physics and technology of cardiovascular and neurovascular imaging under one cover, providing students, professionals, and researchers with a single, state-of-the-art reference.

Discover the Most Advanced Technologies in Biomagnetics Co-edited by Professor Ueno, a leader in the biomagnetics field for over 40 years, Biomagnetics: Principles and Applications of Biomagnetic Stimulation and Imaging explains the physical principles of biomagnetic stimulation and imaging and explores applications of the latest techniques in neuroscience, clinical medicine, and healthcare. The book shows you how the techniques are used in hospitals and why they are so promising. A brief overview of recent research trends in biomagnetics provides you with an up-to-date, informative guide to explore further in this field. The book focuses on three important areas: Magnetic nerve stimulation and transcranial magnetic stimulation Biomagnetic measurements and imaging of the human brain by advanced technologies of magnetoencephalography and MRI Biomagnetic approaches to potential treatments of cancers, pains, and other neurological and psychiatric diseases, such as Alzheimer's disease and depression These core areas of the book were developed from the editors' prestigious graduate-level courses in biomedical engineering. The text also discusses biomagnetic approaches to advanced medicine, including regenerative and rehabilitation medicine.

The product of 20 years of research, this book covers topics in soft tissue elasticity in vivo, from measurement techniques to clinical applications. It provides, for the first time, a single source that systematically introduces the various techniques for in vivo measurement of soft tissue elasticity in an effort to ease the difficulty between learning technical details and clinical applications of techniques. Measurement of Soft Tissue Elasticity in Vivo: Techniques and Applications presents an overview of the existing measurement methods, their physical principles, assumptions, advantages, and disadvantages. Clinical applications discussed include assessment of tissue fibrosis after radiotherapy, articular cartilage degeneration, muscle contraction, cancer staging, liver fibrosis progression, diabetic foot ulceration, cornea stiffening, and wound healing. Techniques covered include shear wave propagation methods, vibro-ultrasound methods, dynamic holography, ultrasound and other indentation methods, and OCT-based and other suction measurement methods. The book also proposes two critical directions for future research in the field. One is to standardize the terms, parameters, and test protocols used in different fields. The second proposal is to standardize one technique to dominate the field, while devices can be adapted to fit the measuring requirements of different tissues. In doing so, the results obtained for the same tissue by different clinicians can be comparable and a standardized protocol can be established. This book bridges the gap between the complexity of measuring techniques and simplicity and accuracy of their clinical use. Its comprehensiveness and clarity help new engineers in the field develop analytical methods and allow clinicians to use these techniques in their practice with greater confidence.

Nonlinear dynamics has become an important field of research in recent years in many areas of the natural sciences. In particular, it has potential applications in biology and medicine; nonlinear data analysis has helped to detect the progress of cardiac disease, physiological disorders, for example episodes of epilepsy, and others. This book focuses on the current trends of research concerning the prediction of sudden cardiac death and the onset of epileptic seizures, using the nonlinear analysis based on ECG and EEG data. Topics covered include the analysis of cardiac models and neural models. The book is a collection of recent research papers by leading physicists, mathematicians, cardiologists and neurobiologists who are actively involved in using the concepts of nonlinear dynamics to explore the functional behaviours of heart and brain under normal and pathological conditions. This collection is intended for students in physics, mathematics and medical sciences, and researchers in interdisciplinary areas of physics and biology.

The Physiological Measurement Handbook presents an extensive range of topics that encompass the subject of measurement in all departments of medicine. The handbook describes the use of instruments and techniques for practical measurements required in medicine. It covers sensors, techniques, hardware, and software as well as information on processing systems, automatic data acquisition, reduction and analysis, and their incorporation for diagnosis. Suitable for both instrumentation designers and users, the handbook enables biomedical engineers, scientists, researchers, students, health care personnel, and those in the medical device industry to explore the different methods available for measuring a particular physiological variable. It helps readers select the most suitable method by comparing alternative methods and their advantages and disadvantages. In addition, the book provides equations for readers focused on discovering applications and solving diagnostic problems arising in medical fields not necessarily in their specialty. It also includes specialized information needed by readers who want to learn advanced applications of the subject, evaluative opinions, and possible areas for future study.

This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. With a focus on explaining the underlying principles, this book examines the physiology and mechanics of circulation, mechanobiology and the biomechanics of different components of the cardiovascular system, in-vivo techniques, in-vitro techniques, and the medical applications of this research. Written for undergraduate and postgraduate students and including sample problems at the end of each chapter, this interdisciplinary text provides an essential introduction to the topic. It is also an ideal reference text for researchers and clinical practitioners, and will benefit a wide range of students and researchers including engineers, physicists, biologists and clinicians who are interested in the area of cardiovascular biomechanics.

A rapidly growing field, vibrational spectroscopy has found applications in industries including pharmaceutical manufacture, food and drug safety, and process monitoring on production lines. In particular, interest in clinical spectroscopy is rising rapidly as researchers recognize the potential of the vibrational spectroscopic techniques-Infrared (IR) and Raman Spectroscopy-as noninvasive tissue diagnosis tools. However, the details of the characteristic peak frequencies and their relationship to specific functional groups present in the biological tissues have not been fully understood. Vibrational Spectroscopy for Tissue Analysis introduces IR and Raman Spectroscopy to those scientists who are either using these spectroscopic techniques to address clinical problems or planning to use spectroscopy to analyze clinical tissues and understand their chemical composition. By compiling the interpretations and understandings of the spectral peaks of the biological molecules in one place, this book aids in the understanding of IR and Raman Spectroscopy, and what these techniques can offer both in early diagnosis of the disease and monitoring of the progression of the disease. Despite the tremendous advances in the field of spectroscopy, where new applications are emerging at the pace of development, there are still areas of research that are crying for further exploration. This book bridges the gap between the spectroscopic research and medical applications.

Fosters a thorough understand of radiation dosimetry concepts: detailed solutions to the exercises in the textbook "Fundamentals of Ionizing Radiation Dosimetry"!

Analytical measurements at the single molecule level under ambient conditions have become almost routine in the past few years. The application of this technology to fundamental studies of heterogeneity in biomolecular structure and dynamics, chemical and biological reaction kinetics and photophysics provides a rich playground for molecular scientists. The potential use of single molecule detection for nanotechnology and quantum information processing is a new and almost unexplored area. This handbook is intended for those interested in a practical introduction to single molecule investigations using fluorescence techniques and places special emphasis on the practicalities of achieving single molecule resolution, analyzing the resulting data and exploration of the applications in biophysics. It is ideal for graduate research students and others embarking on work in this exciting field.

This book discusses fundamentally new biomedical imaging methods, such as holography, holographic and resonant interferometry, and speckle optics. It focuses on the development of holographic interference microscopy and its use in the study of phase objects such as nerve and muscle fibers subjected to the influence of laser radiation, magnetic fields, and hyperbaric conditions. The book shows how the myelin sheath and even the axon itself exhibit waveguide properties, enabling a fresh new look at the mechanisms of information transmission in the human body. The book presents theoretically and experimentally tested holographic and speckle-optical methods and devices used for investigating complex, diffusely scattering surfaces such as skin and muscle tissue. Additionally, it gives broad discussion of the authors' own original fundamental and applied research dedicated to helping physicians introduce new contact-less methods of diagnosis and treatment of diseases of the cardiovascular and neuromuscular systems into medical practice. The book is aimed at a broad spectrum of scientific specialists in the fields of speckle optics, holography, laser physics, morphology and cytochemistry, as well as medical professionals such as physiologists, neuropathologists, neurosurgeons, cardiologists and dentists.

The 19th century pioneers of motor physiology - Helmholtz, Hering, Fick and others - used the mathematics of motion, known as kinematics, to describe the laws of human movement and to deduce the neural control principles underlying these laws. After long neglect - partly due to limitations in stimulation and recording techniques - the kinematic approach is now resurging, fortified with modern computers and electrophysiology. New developments in recording techniques, as well as an improved understanding of the complex control properties of three-dimensional movements, have led to a flood of new research in this area. The classical laws of Donders and Listing have been confirmed and generalized, and computer simulations of the neural control of three-dimensional movement have been developed and tested.
In this book, some of the world's leading scientists of motor control discuss how the brain represents and tranforms the kinematic variables of movement. Background chapters explain the basic concepts - non-commutativity, redundancy and the classical laws - and their application to normal function and motor disorders, and shorter articles describe current research. The contributions are based on presentations at a symposium held in Tubingen in August 1995. The wide scope of the book should enable researchers to gain an overview of current research, but should also help newcomers tot he field to get a good understanding of the questions and problems involved in three-dimensional movement control.

The textbook "Fundamentals of Ionizing Radition Dosimetry" bundled with the workbook containing solutions to the exercises is the perfect pair for anyone seriously interested in radiation dosimetry.