Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfangen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen fur die historische wie auch die disziplingeschichtliche Forschung zur Verfugung, die jeweils im historischen Kontext betrachtet werden mussen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfangen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen fur die historische wie auch die disziplingeschichtliche Forschung zur Verfugung, die jeweils im historischen Kontext betrachtet werden mussen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfangen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen fur die historische wie auch die disziplingeschichtliche Forschung zur Verfugung, die jeweils im historischen Kontext betrachtet werden mussen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

Wer gynakologische Rontgentherapie treiben will, soIl sicn mit Hilfe des vorliegenden Biichleins kurz und schnell iiber aIle cinschlagigen Fragen orientieren konnen. Eine umfassende Dar steIlung des ganzen Gebietes war al>'o nicht beabsichtig," wohl aber eine kritische Beurteilung der in der' eigenen Arbeit sowie in der Literatur gesammelten Erfahrungen. Daher war die Mit teilung einiger von mir ausgefiihrter Versuche nicht zu umgehen. Besonderer Wert wurde auf eine moglichst voIlstandige Angabe der bereits vorhandenen Arbeiten gelegt, um ein leichtes Auf finden der interessierenden Publikationen zu ermoglichen. Eine Statistik liber samtliche in der mir zur Verfiigung stehenden Literatur bekannt gegebenen gynakologischen Bestrahlungen faBt die bisherigen Erfahrungen mit di ser neuen' Behandlungsweise zahlenmaBig zusammen und wird gewiB dem Neuling auf diesem Gebiete ebenso willkommen sein wie dem erfahrenen gynakolo gischen Rontgentherapeuten. Marburg: Februar 1913. Dr. Kirstein. Inhaltsverzeichnis. Seite Vorlaufer der gynakologischen Riintgentherapic. . . . . . . . 1 Tierexperimentelles uber Hoden und Ovarien . . . . . 3 V cranderungen des weiblichen Ovariums durch Riintgenstrahlen 9 Technik der gynakologischen Riintgentherapie 10 Instrumentarium 10 Riintgenriihren 14 Hartemesser 16 Strahlenqualitat . 18 Strahlendosimetrie 20 Kontrolle des Kienbiickschen Quantimeters 23 Desensibilisierung der Haut . . . . . . . 26 Filterung der Strahlen . . . . . . . . . . 28 Versuche zur Feststellung des bosten Filters 29 Sekundarstrahlung . . 34 Felderbestrahlung . . 35 Bestrahlungsmethoden 36 Albers-Schiinberg 36 GauB . 37 Runge. 38 Frankel 39 Kelen . 40 Heynemann 41 Kirstein . . 42 Dessauers Homogenbestrahlung 43 Kritik der Bestrahlungsmethoden . 44 Die gunstigste Zeit zur Bestrahlung . 49 Kosten der Riintgentherapie . . . 51 Theoretisches zur Strahlenwirkung 53 Indirekte Wirkung . 53 Direkte Wirkung. . . . . . . . . 56 Fernwirkung. . . . . . . . . . . 57 Indikationen uIl, d Kontraindikationen zur gynakologischen Riintgentherapie. . . . . 61 Metropathia haemorrhagica 62 Myome . . . . . . . . ."

Die vorliegende Arbeit bezweckt, eine Ubersicht uber die Untersuchungen an radioaktiven Substanzen zu geben, die ich seit mehr als vier Jahren ausfuhre. Der Ausgangspunkt war eine Untersuchung der von Herrn Becquerel entdeckten Uran strahlen. Die Resultate, zu welchen diese Arbeit mich fuhrte, schienen eine so interessante Perspektive zu eroffnen, dass Herr Curie, unter Aufgabe seiner eigenen Arbeiten, sich mit mir ver einigte und wir gemeinsam auf das Ziel hinarbeiteten, die neuen radioaktiven Substanzen zu extrahiren und naher zu er. forschen. Von Anfang unserer Untersuchungen an hielten wir uns fur verpflichtet, Proben der von uns entdeckten und hergestellten Substanzen an einige Physiker zu verleihen, vor allen Dingen an Herrn Becquerel, den Entdecker der Uran strahlen. So haben wir selbst die Untersuchungen andrer uber die radioaktiven Sub stanzen erleichtert. Bald nach unsren ersten Veroffentlichungen befasste sich auch Herr Giesel in Deutschland mit der Herstellung dieser Substanzrn und verlieh ebenfalls Proben davon an mehrere deutsche Physiker. Spater wurden die Substanzen in Deutsch land und Frankreich in den Handel gebracht und die immer mehr zunehmende Wichtigkeit des Gegenstandes wurde die Veranlassung zu einer wissenschaftlichen Bewegung, so dass zahlreiche Arbeiten uber die radioaktiven Korper erschienen sind und noch fort wahrend erscheinen, vor allem im Ausland. Die verschiedenen franzosischen und auslandischen Arbeiten fuhren naturlich zum Teil zu gleichen Resultaten, wie bei jedem neuen und in Bildung Curie, Untersuchungen Uber radioaktive Substanzen. 1 2 begriffenen Wissenszweig. Das Aussehen der Frage andert sich sozusagen von Tag zu Tag."

Skull base anatomy is extremely complex, with vital neurovascular structures passing through multiple channels and foramina. Brain tumors such as pituitary tumors, acoustic neuromas, and meningiomas are challenging to treat due to their close proximity to cranial nerves and blood vessels in the brain, neck, and spinal cord. Medical imaging is an essential tool for identifying lesions and critical adjacent structures. Detecting and precisely mapping out the extent of disease is imperative for appropriate and optimal treatment planning and ultimately patient outcome. Eugene Yu and Reza Forghani have produced an exceptional, imaging-focused guide on various neoplastic diseases affecting the skull base, with contributions from a Who's Who of prominent radiologists, head and neck surgeons, neurosurgeons, and radiation oncologists. The content is presented in a clear and concise fashion with chapters organized anatomically. From the Anterior Cranial Fossa, Nasal Cavity, and Paranasal Sinuses - to the Petroclival and Lateral Skull Base, an overview and detailed analysis is provided for each region. Key Highlights Fundamentals of skull base imaging, including recent developments in diagnostic modalities More than 400 radiographs, color anatomical drawings, and color intraoperative photos elucidate the imaging appearances of a wide spectrum of disease affecting the skull base, as well as important anatomic variants and pathways of disease spread Clinically oriented imaging approach focuses on diagnostic and prognostic features important in the evaluation of skull base abnormalities Atlas of skull base CT and MRI anatomy provides an easy to access, quick reference for identifying important anatomic landmarks Insights on the pathways of tumor growth and the role of clinical imaging in the management of skull base cancers Critical and contrasting viewpoints from multidisciplinary experts provide a well-rounded perspective This invaluable resource chronicles current knowledge in state-of-the-art skull base tumor imaging with clinical pearls on pathophysiology, prognosis, and treatment options. It is a must-have for radiology, neurosurgery, and otolaryngology residents and clinicians who care for patients with head and neck neoplasms.

Super-Resolution imaging refers to modern techniques of achieving resolution below conventional limits. This book gives a comprehensive overview of mathematical and computational techniques used to achieve this, providing a solid foundation on which to develop the knowledge and skills needed for practical application of techniques. Split into five parts, the first looks at the mathematical and probabilistic tools needed, before moving on to description of different types of imaging; single-wave, anomaly, multi-wave and spectroscopic and nanoparticle.As an important contribution to the understanding of super-resolution techniques in biomedical imaging, this book is a useful resource for scientists and engineers in the fields of biomedical imaging and super-resolution, and is self-contained reference for any newcomers to these fields.

Readable, practical and concise, Nuclear Cardiology is a self-contained guide to this cardiac imaging subspecialty. Including both technical and clinical aspects, it provides a foundation of essential knowledge common to practitioners from any background. This title covers radiation physics, biology and protection, and addresses all areas of imaging including the design and operation of the gamma camera (including solid-state cameras), single photon emission computed tomography (SPECT) acquisition and processing, and image interpretation and writing of reports. Stress testing and radiopharmaceuticals are explained in detail, as is the evidence-base underpinning myocardial perfusion scintigraphy. Newer radionuclide imaging techniques are well-covered (e.g. phosphate scintigraphy in cardiac amyloidosis), as is the expanding field of cardiac positron emission tomography (PET). Fully updated with coverage of new indications for gamma camera imaging, increased focus on attenuation correction and SPECT-CT and detail on the design use and clinical implications of solid-state gamma cameras throughout, this second edition of the essential text for nuclear cardiology trainees and practitioners is fully illustrated with colour plates to aid clinical practice. Presented in the bestselling Oxford Specialist Handbook format, Nuclear Cardiology provides core knowledge for those training in the subspecialty, whether at a basic or advanced level or from a medical or technical background, and is a key resource for those seeking to accredit in the subspecialty.

Nuclear cardiology is one of the most widely used non-invasive techniques for the assessment of coronary artery disease and other cardiovascular conditions. It has proved to be a cost effective tool for the evaluation and management of cardiac patients and usually has a decisive role for diagnosis, prognosis and risk stratification. In particular, radionuclide myocardial perfusion imaging (MPI) is used extensively worldwide for the evaluation of known or suspected coronary artery disease, with an estimated 15-20 million procedures performed annually. This publication provides a detailed analysis of all the steps involved in the delivery of nuclear cardiology services, from referrals to reporting, and is intended to serve as guidance for the implementation, homogenization and enhancement of MPI practice in those Member States where the technique is under development.

Ultrasound has been imaging modality of poor man since 50 years. With computer revolution it has acquired exquisite quality at turn of century. Its capabilities have not yet been fully recognized and described.

Imaging plays an integral role in the diagnosis and intervention of debilitating, often fatal vascular diseases of the brain, such as ischemic and hemorrhagic stroke, aneurysms, and arteriovenous malformations (AVMs). Written by a world renowned neuro-radiologist and pioneer in the early adoption of magnetic resonance (MR) technology, Imaging of Cerebrovascular Disease is a concise yet remarkably thorough textbook that advances the reader's expertise on this subject. The text draws on the author's vast personal experience, case studies, and traditional educational sources, offering didactic dialogue with accompanying images. A practical clinical resource organized into six chapters, this book offers unparalleled breadth in delineating the diagnostic and treatment usages of modern imaging techniques. Chapter one sets a foundation with extensive coverage of modalities and their applications, including MR, computed tomography (CT) and digital subtraction angiography (DSA). Subsequent chapters cover utilization of imaging techniques specific to underlying pathologies. Key Features: In-depth discussion of medical and neuroradiologic/neurosurgical interventions, focusing on the use of imaging prior to, during, and following treatment Comprehensive text enhanced with more than 700 high-quality images Detailed evaluation of normal brain anatomy, as well as gyral anatomy in brain ischemia, an important subtopic Advantages, disadvantages, mortality, and morbidity of surgery (clipping) versus endovascular techniques (coiling and flow diversion) for aneurysms Presented in a style that facilitates cover-to-cover reading, this is an essential tool for residents and fellows, and provides a robust study guide prior to sitting for relevant certification exams. It is also a quick, invaluable reference for radiologists, neurosurgeons, and neurologists in the midst of a busy clinical day.

In 194 cases featuring over 450, high-quality images, Nuclear Medicine and PET/CT Cases provides a succinct review of clinically relevant cases covering the full range of nuclear medicine. Cases are grouped into sections including: Nuclear CNS Imaging, Nuclear Inflammation/Infection Imaging, Ventilation/Perfusion Lung Scintigraphy, Pediatric Nuclear Medicine, Cardiac Imaging, Bone Scintigraphy, PET/CT in Oncology, General Oncologic Imaging, Thyroid and Parathyroid, Radionuclide Therapy and Pre-Therapy Evaluation, Liver, Spleen and Biliary Tract, Gastrointestinal Tract, Renal Scintigraphy. Part of the Cases in Radiology series, this book follows the easy-to-use format of question and answer in which the patient history is provided on the first page of the case, and radiologic findings, differential diagnosis, teaching points, next steps in management, and suggestions for furthering reading are revealed on the following page. This casebook is an essential resource for radiology residents and practicing radiologists alike.

This book discusses cell response to external electromagnetic and magnetic fields. A new ecological factor, artificial electromagnetic fields (EMF), is a cause for public concern. This book suggests that the cellular response to EMF and to magnetic fields is the base of response of the human organism to EMF. Processes of gene activity are especially important in understanding the EMF influence on cells. The historical review of investigations of cell reactions with special attention to the investigations in the Soviet Union is discussed, as is the EMF-induced increase in cell membrane permeability to ions, mutagenesis, and induction of DNA strand breaks, cell nucleus microelectrophoresis, and the state of chromatin in living cells.

Imaging-Guided Interventional Breast Techniques instructs the reader on the performance of invasive breast procedures and discusses issues related to the selection and purchase of equipment to perform these cutting edge techniques. This "how to" text will include the most up-to-date information on biopsy technology, including the advantages and disadvantages of biopsy probes. The book will also address issues of patient management and discuss the results of the latest stuides on problems in the histopathologic interpretation of tissue obtained during biopsies. Additionally, the book is designed to assist the physician in assessment of equipment in compliance with professional regulations. Enhanced by over 200 high quality images, this text is ideal for specialists who perform interventional breast procdures.

Drs. Vitola and Delbeke assembled a group of standout contributors in order to create a resource that advances the knowledge and skills of experienced nuclear cardiologists and radiologists while also preparing residents for the cutting-edge field of nuclear cardiology. Diagnostic tools, physics and instrumentation, and radiopharmaceuticals and protocols central to the field are examined. The comprehensive text covers key applications of myocardial perfusion imaging, including applications in special populations and in emergency departments. Risk assessment, pitfalls, and artefacts are addressed. Additional chapters detail the value of cardiac MRI, multislice computed tomography, stress echocardiography, and PET and PET/CT to nuclear cardiology. Practical case presentations and a wealth of illustrations reinforce instruction on diagnostic guidelines and methods.

biochemische und okologische Aspekte der Resistenzentstehung in Mikro- organismen und in Tumorzellen, Probleme und Moglichkeiten der kombinierten Anwendung von Chemotherapeutika und die logistischen und wissenschaftlichen Grundlagen fUr die Suche nach neuen Chemotherapeutika abgehandelt. Die Frage nach den Urspriingen der Chemotherapie fUhrt auch zu den Schwachen, die bereits im Konzept dieser therapeutischen Disziplin liegen und die der An- wendung der Chemotherapie Grenzen setzen. Von dies en Grenzen und von Moglichkeiten, sie zu uberwinden, ist im letzten Kapitel die Rede. DaB ein Text wie der vorliegende nicht alle Aspekte der Chemotherapie in gleicher Ausftihrlichkeit behandeln kann, versteht sich fast von selbst. Dieses Buch enthalt keine enzyklopadische Darstellung der Chemotherapie, sondern die Erlauterung einiger ihrer prinzipiellen Probleme. DaB die hierzu herangezogenen Beispiele vorwiegend aus der antimikrobiellen und antineoplastischen Chemo- therapie stammen, hangt mit den personlichen Interessen und Erfahrungen des Autors zusammen. An einigen Stellen des Buches werden Fragen erortert, die noch ungelost sind. Zuweilen wird in einer kontroversen Frage sogar Partei ergriffen. Der Autor hofft, die "Subjektivitat" derartiger AuBerungen deutlich genug kenntlich ge- macht zu haben. 1m ubrigen dilrften so1che gelegentlich unterlaufenen Abwei- chungen yom Tugendpfad der Lehrbuchtradition der Lebendigkeit der Darstel- lung zugute kommen. Dieses Buch mochte nicht nur informieren, es will auch anregen und zum Widerspruch herausfordern. Mit diesem Anliegen wendet es sich an aIle, die sich mit der Chemotherapie beschiiftigen wollen oder die Chemotherapie bereits in irgendeiner Form praktizieren, also an Medizinstuden- ten, Ante, Mikrobiologen und Pharmakologen.

As medical imaging plays an increasingly important role in the diagnosis and treatment of patients, it has become vital for medical practitioners to have a thorough understanding of the many complicated techniques available. The Oxford Handbook of Medical Imaging is a practical quick-reference guide to all the modalities and techniques of imaging for medical and surgical conditions. Practical and easy to use, the handbook covers all common diagnoses, symptoms, and conditions. Medical and surgical emergencies are covered, along with explanations of the rationale behind each imaging techinque and the common questions likely to be asked. Fully illustrated throughout with example images from real cases, the indications, merits, and drawbacks of all the various modalities are explained in quick bullet points for ease of understanding and quick reference. Each chapter (where appropriate) is split into handy sections on differential diagnosis, presenting symptoms, and common conditions, so you will always have the most relevant information at your fingertips. This handbook is sure to be a constant companion for all radiographers and students, junior doctors, clinicians, and anyone who works with medical imaging.

Compiled from sessions presented at the 2008 AAPM Summer School, which was held June 25-27, 2008 at the Baylor College of Medicine, Texas Medical Center, Houston, TX. Topics include PET and CT basics, diagnostic and clinical alications, PET/CT scanner designs and characteristics, scanner testing, PET ACR accreditation and acceptance testing, PET/CT simulation for therapy alications, shielding calculations and radiation safety, and site planning.

This open access book presents a wide portfolio of examples of positron emission tomography coupled with computer tomography (PET/CT) studies in various cardiac conditions in order to provide a rationale for the implementation of this technology in an array of clinical conditions. Cardiovascular diseases are a major contributor to premature morbidity and mortality worldwide. Low- and middle-income countries (LMICs) are particularly affected by cardiovascular diseases (CVDs), with more than 75% of all CVDs deaths occurring in these countries. For this reason, target 3.4 of the United Nations (UN) Sustainable Development Goals (SDGs) agenda aims at a 30% reduction in premature mortality due to non-communicable diseases (NCDs), which include CVDs, by 2030. Among CVDs, ischemic heart disease (IHD) plays an important role and, according to the Institute for Health Metrics and Evaluation (IHME), it was responsible for 15.96% of global deaths in 2017. Between 2000 and 2017, the number of IHD deaths worldwide increased by 0.26% per year. Several imaging tools help to non-invasively diagnose, stratify risk and guide management in cardiac disease. They include nuclear cardiology techniques, using either SPECT (single photon emission computed tomography) or PET/CT. While myocardial imaging with SPECT has been fully embraced by the cardiology community and is widely available worldwide, PET/CT introduction has been slower, due not only to its higher costs, but also to the limited availability of PET/VCT scanners, mostly utilized for oncological applications. This book is an invaluable tool for nuclear medicine physicians, cardiologists and radiologists.

The present volume on basic physics of ultrasonographic imaging procedures provides clear and concise information on the physics behind ultrasound examinations in diagnostic imaging. It attempts to present the subject from a simple approach that should make it possible for the target groups to comprehend the important concepts which form the physical basis of ultrasonic imaging. The main target group of this manual is radiological technologists and radiographers working with diagnostic ultrasound in developing countries.Clinicians and nurse practitioners may also find the simple presentation appealing. A conscious effort has been made to avoid detailed mathematical treatment of the subject. The emphasis is on simplicity.

This monograph evaluates the evidence for carcinogenicity of ionizing radiation from internally deposited radionuclides. The radionuclides considered in this monograph belong to two broad categories: those that emit a-particles (helium nuclei) and those that emit b-particles (electrons) during their primary radioactive decay. For purposes of this monograph 'internally deposited' refers to radionuclides in dispersed forms (e.g. dusts suspensions solutions or gases) that enter the body through inhalation ingestion by some form of injection or in some cases by percutaneous absorption. Radionuclides may also enter tissues within removable objects, such as radioactive beads needles etc. that may be implanted surgically for therapeutic purposes or other kinds of fragments implanted accidentally. These kinds of exposures are not considered in this volume. Also not considered are radionuclides (e.g. iron-55 gallium-67) which undergo radioactive decay through processes that do not include emission of either a or b particles. Radon and its decay products were previously evaluated in "IARC Monographs" Volume 43 (1988) as "carcinogenic to humans" (Group 1). The subsequently published scientific literature on occupational and residential exposures to radon was reviewed and included in this volume as an update but no re-evaluation of radon was considered necessary. Six specific radionuclides of the elements radium thorium plutonium and phosphorus plus mixed radionuclides of iodine were evaluated as "carcinogenic to humans "(Group 1) on the basis of sufficient evidence for increased risk of cancer in exposed individuals. These include radium-224 radium-226 radium-228 thorium-232 (administered in colloidal form as thorium-232 dioxide) plutonium-239 (exposure to which also entails exposure to plutonium-240 and other isotopes of plutonium) radioisotopes of iodine including iodine-131 and phosphorus-32. Evidence for increased cancer risk in exposed humans is from medical usage in the cases of radium-224 thorium-232 and phosphorus-32 and from occupational or accidental/environmental exposures for plutonium-239 radium-226 and radium-228 and the radioiodines. In addition the global evaluations of two broad categories of internally deposited radionuclides were made on the basis of carcinogenicity in experimental animals plus other relevant data: Internally deposited radionuclides that emit a particles are "carcinogenic to humans (Group 1)." Internally deposited radionuclides that emit b particles are "carcinogenic to humans (Group 1). Ionizing Radiation Part 1: X-and Gamma (g) Radiation and Neutrons" Volume 75 of the "Monographs" addressed the carcinogenic potential of external X-rays g-rays and neutrons in exposed populations (see overleaf).

Das Buch stellt die Grundlagen der Anwendung, Prufung und Bewertung diagnostischer Massnahmen in der Medizin zusammen. Dabei liegt der Schwerpunkt auf der systematischen Darstellung der vier Phasen des Evaluierungsprozesses. Das Buch wendet sich an Mediziner, die sich mit der Erforschung und Evaluierung diagnostischer Massnahmen befassen. Der Begriff der Evaluierung bezieht sich dabei ausschliesslich auf die Verbesserung der Patientenversorgung und orientiert sich nicht primar an einer finanziellen Kosten-Nutzen-Abschatzung. Die Autoren schliessen mit diesem nutzlichen Buch eine Lucke im deutschen Sprachraum.

Top Score for the Radiology Boards: Q & A for the Core and Certifying Exams is the ideal diagnostic radiology board prep resource. Written by radiologist Alan Weissman, with contributions from dozens of leading experts at renowned institutions, Top Score has a simple ambition: to improve your test scores. The book covers all exam categories, including non-interpretive skills (NIS), physics, safety, breast, cardiac, diagnostic radiology, gastrointestinal, genitourinary, interventional, musculoskeletal, neuroradiology, nuclear, pediatrics, thoracic, ultrasound/reproductive/endocrinology, vascular, and general radiology. Chapters are composed of four types of test cases of varying focus and complexity, each on a two-page spread. Essentials starts with a patient presentation, followed by board-type multiple-choice questions. Details begins with a case presentation, followed by 10 rapid-fire questions, enabling brisk, high-volume learning. Image Rich presents multiple images that require accurate identification, enabling accelerated, high-volume image assessment practice. More Challenging follows the same format as Essentials but adds a higher degree of difficulty. Key highlights High-quality, board-type Q&A with detailed answer explanations High yield "Top Tips" for each case Special radiology artifacts section Image Rich and Details sections aid in rapid and lasting topic mastery Comprehensive review, covering all sections tested by the American Board of Radiology Written by experienced, expert question writers NIS chapter emphasizes proficiency in vital practice-related skills This quintessential home-study guide will help radiology residents and fellows prep for and ace both the certifying and core exams.