First published in 1992, AY's Neuroanatomy of C. elegans for Computation provides the neural circuitry database of the nematode Caenorhabditis elegans, both in printed form and in ASCII files on 5.25-inch diskettes (for use on IBM (R) and compatible personal computers, Macintosh (R) computers, and higher level machines). Tables of connections among neuron classes, synapses among individual neurons, gap junctions among neurons, worm cells and their embryonic origin, and synthetically derived neuromuscular connections are presented together with the references from which the data were compiled and edited. Sample data files and source codes of FORTRAN and BASIC programs are provided to illustrate the use of mathematical tools for any researcher or student interested in examining a natural neural network and discovering what makes it tick.

Thoroughly examining the popular and expanding field of reproductive toxicology, this newly revised and expanded Third Edition provides the latest, cutting-edge scientific developments in this constantly evolving discipline. Reproductive Toxicologya (TM)s contributors are experienced regulatory agency and Clinical Research Organization representatives who currently utilize the new techniques discussed in the text and continue to revolutionize reproductive toxicology research.

This ground-breaking resource includes:

• New and important critical mechanistic topics such as epigenetics and omics
• The first significant compilation of epigenetic mechanisms
• An in-depth analysis of the role of genomics, proteomics, and metabolomicsin human reproduction
• New guidelines with respect to the latest research applications in the field

Anaesthesiologists regularly administer potent, and potentially toxic, drugs that profoundly interfere with fundamental physiological functions such as breathing, cardiac output, blood pressure, the protective reflexes and the perception of pain. Reviewing all aspects of human physiology, Physiology for Anaesthesiologists provides a working knowledge of physiological principles and their application to anaesthesia and intensive care. The text covers the various systems of the human body, from the central nervous system to the liver and kidneys. The reader gains an understanding not only of each system discussed, but also of how each of those physiological systems interact with each other. The section on pain, for example, explains how the body warns of dysfunction in one or more systems. In addition to covering the core material for professional examinations, some topics not usually dealt with in textbooks for anaesthetists are also covered, such as the impact of anaesthesia and surgery on the immune system. Written in a clear and concise style, the book supplies up-to-date information to trainees in anaesthesiology and related specialities preparing for professional examinations: both editors have a wealth of experience in these subjects. The book also helps established anaesthesiologists, and those in other related specialities, who want to keep up with recent developments in the field.

A comprehensive survey of the use of ultrasound in management of infertile patients is presented in this publication. Particular atten-tion is given to recently developed techniques such as assessment of endometrial changes, ovarian blood flow measurements, and per-cutaneous oocyte retrieval for in vitro fertilization. The very re-cent technique of transvaginal sonography is presented and richly illus-trated with original results obtained in biopsy-guided oocyte re-trieval, and in the precise delineation of follicle size and number for infertility treatment. Guidance in the interpretation of ultrasonic findings, which include potential limitations and pitfalls, is provided in each chapter. Researchers and practitioners interested in the management of infertile patients will find this volume indispensable.

Statistical Analysis of Human Growth and Development is an accessible and practical guide to a wide range of basic and advanced statistical methods that are useful for studying human growth and development. Designed for nonstatisticians and statisticians new to the analysis of growth and development data, the book collects methods scattered throughout the literature and explains how to use them to solve common research problems. It also discusses how well a method addresses a specific scientific question and how to interpret and present the analytic results. Stata is used to implement the analyses, with Stata codes and macros for generating example data sets, a detrended Q-Q plot, and weighted maximum likelihood estimation of binary items available on the book's CRC Press web page. After reviewing research designs and basic statistical tools, the author discusses the use of existing tools to transform raw data into analyzable variables and back-transform them to raw data. He covers regression analysis of quantitative, binary, and censored data as well as the analysis of repeated measurements and clustered data. He also describes the development of new growth references and developmental indices, the generation of key variables based on longitudinal data, and the processes to verify the validity and reliability of measurement tools. Looking at the larger picture of research practice, the book concludes with coverage of missing values, multiplicity problems, and multivariable regression. Along with two simulated data sets, numerous examples from real experimental and observational studies illustrate the concepts and methods. Although the book focuses on examples of anthropometric measurements and changes in cognitive, social-emotional, locomotor, and other abilities, the ideas are applicable to many other physical and psychosocial phenomena, such as lung function and depressive symptoms.

Debating Human Genetics is based on ethnographic research focusing primarily on the UK publics who are debating and engaging with human genetics, and related bio and techno-science. Drawing on recent interviews and data, collated in a range of public settings, it provides a unique overview of multiple publics as they 'frame' the stake of the debates in this emerging, complex and controversial arena.

The book outlines key sites and applications of human genetics that have sparked public interest, such as biobanks, stem cells, genetic screening and genomics. It also addresses the 'scientific contoversies' that have made considerable impact in the public sphere - the UK police DNA database, gene patenting, 'saviour siblings', and human cloning. By grounding the concepts and issues of human genetics in the real life narratives and actions of patient groups, genetic watchdogs, scientists, policy makers, and many other public groups, the book exemplifies how human genetics is a site where public knowledge and value claims converge and collide, and identifies the emergence of 'hybrid publics' who are engaging with this hybrid science.

Debating Human Genetics is based on ethnographic research focusing primarily on the UK publics who are debating and engaging with human genetics, and related bio and techno-science. Drawing on recent interviews and data, collated in a range of public settings, it provides a unique overview of multiple publics as they 'frame' the stake of the debates in this emerging, complex and controversial arena. The book outlines key sites and applications of human genetics that have sparked public interest, such as biobanks, stem cells, genetic screening and genomics. It also addresses the 'scientific contoversies' that have made considerable impact in the public sphere - the UK police DNA database, gene patenting, 'saviour siblings', and human cloning. By grounding the concepts and issues of human genetics in the real life narratives and actions of patient groups, genetic watchdogs, scientists, policy makers, and many other public groups, the book exemplifies how human genetics is a site where public knowledge and value claims converge and collide, and identifies the emergence of 'hybrid publics' who are engaging with this hybrid science.

This book is dedicated to those who died of malignant hyperthermia and to their families. It contains cases studies that would be helpful for anesthesiologists, surgeons, physiologists, molecular biologists, biophysicists, biochemists, pathologists, students, and post doctoral fellows.

Awarded with the 2018 Prose Award in Clinical Medicine, the third edition of Principles of Gender-Specific Medicine explored and described exciting new areas in biomedicine that integrated technology into the treatment of disease and the augmentation of human function. Novel topics such as the sex-specific aspects of space medicine, the development and the use of genderized robots and a discussion of cyborgs were included in the third edition, providing a preview of the expanding world of sex-specific physiology and therapeutics. This Fourth Edition is a continuation of the mission to trace the relevance of biological sex to normal function and to the experience of disease in humans. We are now twenty years into the postgenomic era. The investigation of how the genome produces the phenome has led to fascinating insights as well as yet unanswered questions. Principles of Gender-Specific Medicine, Fourth Edition, has a central theme: discuss advances in understanding the role of epigenetics in regulating gene expression in a dynamic, sex-specific way during human life. It explores the protean role of epigenetics in human physiology, the relevance of environmental experience to human function, the therapeutic promise of cutting-edge methodologies like gene manipulation, the preparation of humans for space travel, the use of artificial intelligence in detection and therapeutic decisions concerning disease states, the possibilities for technological support of not only compromised individuals but of the augmentation of human function, and an analysis of the benefits, limitations and issues that surround our current expectations of personalized medicine.

Boost your exam chances with this brand new workbook and revision guide, designed to improve and assess your knowledge of anatomy and physiology theory and how it applies to practical treatments. - Prepare for success with comprehensive coverage of anatomy and physiology by body system - Coach yourself with a variety of workbook activities for self-study - Test yourself with multiple-choice and exam-style questions - Combine your workbook with Helen McGuinness's bestselling Anatomy and Physiology textbook (sold separately) for the strongest anatomy and physiology support in your Beauty Therapy studies

In the twentieth century, all developed nations began to undergo unprecedented demographic changes, as their birth rates declined, and life expectancies increased significantly --an average of thirty years in less than a century. These developments have caused major transformations in the composition of populations in these countries, especially in terms of the proportions of the various age groups. While the age groups of children and adolescents have decreased, those of elderly persons aged 65 and over, have increased.

Consistent with the situation in other developed nations, the absolute number and percentage of elderly persons in the Israeli population is increasing, while the percentage of younger persons is decreasing. Israel, however, differs from other developed countries in the pace of this demographic change, the composition of its population, and the ways it can address needs related to aging. The demographic figures in Israel indicate that not only is the proportion of elderly persons in the total population growing, but that the old population itself is rapidly aging as well.

This volume exemplifies how social science research can promote knowledge about and understanding of needs and opportunities for adaptation, and assist in evaluating the outcomes of policies and services on the personal, community and national levels, as well as suggest required changes. The variety of topics covered in this volume on age-related research, policies and practice reflects a wide range of research by Israeli scholars on social aspects of aging. Their research offers a glimpse into the knowledge base that has been built over the years on the aging process in Israel, the population of elderly people, and the national policies and network of services for the aged. Other developed countries with aging populations have much to learn from the Israeli experience.

This book stems from the author's clinical experience working with infertile women in psychotherapy and psychoanalysis. It highlights the crucial importance of integrative work of psychotherapists and psychoanalysts with reproductive medical specialists in assisted reproductive technology (ART).

300 full-colour cards on 14 human body systems, covering parts that could not be covered on our first set of cards. To truly offer the benefit of flash cards for memory retention, we included the maximum number of body part labels per card that short-term memory can retain and move to long-term memory. This second set adds a few systems beautifully illustrated by award winning medical illustrator Vincent Perez. With images and numbered labels naming parts on one side and just the numbered parts on the other, students can easily test themselves or their study partner. There is nothing else that compares in quality, number of cards and price. Suggested uses: Students -- establish your core memory of human anatomy whether you will be a nurse, physical therapists, pre med, or even a massage therapist.

Originally published in 1933 Functional Affinities of Man, Monkeys and Apes gives a taxonomic and phylogenetic survey and the findings of diverse experimental investigations of lemurs, monkeys, and apes. The book discusses the inter-relationships of different Primates and emphasizes seldom-used approaches to the question of primate phylogeny. The book attempts to show how little they have been systematically tried, and argues for a regard to the proper place of functional investigations in the study of the classification and evolution of Primates. This book will be of interest to anthropologists, scientists and historians alike.

Originally published in 1960, The Future of Man is a chronicle of Professor Medwar's Reith lectures of 1959. The book outlines his predictions about the future estate of man, with the 'process of foretelling, rather than with what is actually foretold'. He asks, can we predict the future size of populations? What is the evidence and theoretical background for the belief that human intelligence is declining? Could human beings become uniformly excellent or is inborn diversity and inequality a necessary part of the texture of human populations? The lectures tried to answer these questions and attempts to end with a definition of the biological standing of man. This book will be of interest to anthropologists, biologists and natural historians.

Originally published in 1972, Homo Sapiens examines how humans emerged from among the millions of other species and achieved our unique position within the animal kingdom. The book examines what direction future evolution will take and what may be regarded as the 'meaning' of human existence. It stipulates that these are the questions for which no real basis of discussion existed before the 20th century, and at the time of publication, some were still without a definite answer. The book sets out analyse these questions and the continuing debate that has arisen from their study. This is an account of the uniqueness of man in the animal kingdom, how this uniqueness arose during evolution, and what traces of it can be detected in animals other than man. The book describes the mental and physical evolution of man, from his earliest ancestors to the present day. He also gives an account of man's cultural development seeking to establish that there is an underlying principal of cultural evolution, a principle that has been denied by many historians. Later chapters deal with the future and with possible forecasts of mankind's further physical, intellectual and cultural evolution.

The Cassell Hospital Monograph Series, No. 1. The first in a series of monographs, intended to present accessible teaching material concerned with the practice of residential care.

Integrates Student Knowledge of Nutrition Science with Physiology Today's knowledge of human health demands a multidisciplinary understanding of medically related sciences, and Case Studies in the Physiology of Nutrition answers the call. Dedicated to the integration of nutrition science with physiology, this text cohesively incorporates descriptions of human problems in order to stimulate students' critical thinking about how the body integrates various physiological factors to maintain homeostasis. Contains Key Points, Vocabulary Exercises, and Critical Thinking Problems This textbook uses short story-type case studies about fictional individuals who have health problems in order to address a range of issues in an approachable manner. The studies vary in difficulty, with some being straightforward with very simple answers, while others require in-depth thinking and literature research to solve. Each study presents patient background, symptoms, clinical finding, and questions to ponder. Upon qualifying course adoption, this book also includes a valuable instructor's manual, which provides solutions to exercises, problem analysis, and resolution to each case study. This ready-to-implement resource addresses: Homeostasis Obesity and malnutrition Anemia and diabetes Nutrient-gene expression Immune system Food safety Aging and nutrition Muscle and bone studies Case Studies in the Physiology of Nutrition provides an understanding of nutritional components by defining biochemical, mechanical, and physical functions. Its unique approach will aid students in relating functionality to system failure as well as understanding the role of environment in health and nutrition.

There exists today a fast growing availability of personal genetic information. Its prognostic impact and value for an individual or family member's health is sometimes unclear, whilst at other times it is clear-cut. The issue of whether to disclose genetic information does however have wide ranging implications. Avoiding the rhetoric of 'genetic exceptionalism', and drawing on an expanded field of bioethical, sociological and anthropological research, this book sets a new agenda for discussing the ethics surrounding the disclosure of prognostic genetic information. A hermeneutical approach reconsiders the ethics of disclosure in a variety of contexts in which genetic information is generated, requested, interpreted or communicated - from the provider perspective, but also from the moral perspectives of clients and their families. It is in situations of disclosure, in these different contexts, that genetic information meets morality. Providers and recipients can become vulnerable to the revelation or concealment of information, and the forms in which it may be provided. Disclosure Dilemmas invites readers to explore these contexts from an ethical viewpoint and will be a valuable resource for anyone with an interest in biomedical ethics.

Keeping up with the rapid growth in this field, A Practical Manual of Hysteroscopy and Endometrial Ablation: A Clinical Cookbook covers current and emerging endometrial ablation procedures. It provides practical, step-by-step illustrated descriptions of basic and advanced techniques and new methods. The editors, Resad Pasic and Ronald L. Levine, have brought together a group of experts renowned not only for their knowledge but also their ability to teach. The subtitle, A Clinical Cookbook, was purposely chosen to emphasize that you can literally follow the individual "recipes" of procedures to assure their safe and effective use. Containing the most up-to-date and thorough material available, the book addresses the present hysteroscopic therapies and provides in depth discussion of the current knowledge of hysteroscopy and ablation techniques. Each chapter has the main points highlighted in boxes separated from the text for easy review. The digital drawings were made by use of computer graphics by an outstanding graphic designer, Branko Modrakovic. The illustrations, whether line drawings or actual color photographs, clearly deliver the message. You can quickly grasp what to do, and just as importantly, what not to do.

If you had a dependable method for determining the healthiest and most viable conceptus from a cohort of growing preembryos, replacing more than a single one in order to achieve good pregnancy rates would be moot. Sometime in the not-so-distant future, this may be a reality. Taking a step towards that future, An Atlas of Human Blastocysts vividly illustrates the typical and atypical morphology of mammalian blastocysts. The atlas demonstrates that extended culture of blastocysts is now achieveable in the laboratory and points us toward the day when it will be possible to choose between a number of healthy hatched blastocysts.

Carrier testing of adults provides information about the risk of passing a genetic mutation to your children, leading to reproductive (and some say, eugenic) decisions. Excessive carrier screening may have adverse effects, but it can also prevent suffering and open up new reproductive options. Raz's study focuses on the interplay of community genetics (the medical organisation of carrier screening) and genetic alliances (networks of individuals at risk), exploring how 'genetic communities' are emerging both within existing ethnic groups and around patients' organizations.

While the interplay between carrier testing, reproduction and eugenics has sparked many discussions, this study provides a novel and much-needed perspective on its actual implementation and interpretation by community members. Conflating a cross-cultural spectrum of genetic communities, the benefits and perils of supporting (or restricting) carrier screening are located within broader social issues such as religion, ethnicity, multi-culturalism, abortion, stigmatization, suffering and care-giving. While carrier screening emerges as ultimately a morally justified pronatalist endeavour for the reduction of suffering, thus being different in principle from the 'old' eugenics, it can also carry unintended adverse consequences if left unattended to consumers, communities, or health professionals.

Although attitudes toward the aged and their care are inherent in any society, gerontology itself is a relatively recent field of study and practice. "Gerontology and the Construction of Old Age" applies the methods of discourse analysis and textual analysis to texts and documents in this newly evolved and eclectic fi eld. Green explores and identifies the literary methods and discursive regularities through which aging and the aged have been made into objects of study and treatment, and which together form a mode of knowledge production that will infl uence future texts in the field.

Because such formats of representation limit rational diagnoses of problems and rational courses of ameliorative action, policy implications in the fi eld of gerontology are a major interest of this study. Another interest is methodological. Within the broader constructionist approach to social reality, Green takes the position of "constitutive realism" the notion that social reality is linguistically constructed, primarily in speech and writing.

The book's two aims are to describe analytically the fi eld of gerontology. The field is important both for its growing academic presence and for its practical eff ects on discourse and policy concerning old age. It also hopes to help develop possibilities of inquiry associated with the linguistic, literary, and rhetorical turns of social science in recent years. "Gerontology and the Construction of Old Age" is a substantive investigation, at considerable theoretical depth, of gerontology itself, as well as a methodological treatise with broader implications for social science as it focuses upon the discourse of various professional fields.

When human muscle fatigues, athletic performance becomes impaired. For those individuals suffering muscle or metabolic diseases the effects of muscle fatigue can make everyday tasks difficult. Understanding the scientific processes responsible for skeletal muscle fatigue is therefore central to the study of the physiology of sport, exercise and health.

Written by a team of leading international exercise scientists, this book explores the mechanisms of muscle fatigue and presents a comprehensive survey of current research on this important topic. Examining the wide variety of protocols, assessment methods and exercise models used to study muscle fatigue, the book explores the differential effects of fatigue as influenced by:

• age
• gender
• fitness and training
• the use of ergogenic aids
• medical conditions including cerebral palsy, muscular dystrophy and glycogenosis.

Human Muscle Fatigue covers both clinical and applied approaches in sport and exercise physiology and devotes an entire section to the conceptual framework underpinning research in this area, helping readers from a wide range of backgrounds to engage with the topic. Accessible and detailed, this book is a key text for students and practitioners working in exercise and sports science, medicine, physical therapy and health.

The Vagus Nerve in Therapeutic Practice is a comprehensive guide that empowers holistic healers and complementary medicine practitioners with practical, science-based techniques to improve vagal performance and restore mind-body health. This excellent resource has been tailored for professionals to give them a solid understanding of vagus nerve regulation and provides accessible strategies to help their clients.