This is a carefully illustrated volume of surgical procedures. Well-known standard as well as alternative procedures in surgery of the stomach and the proximal duodenum are depicted with anatomical exactness. Possible complications, errors, and dangers and how to avoid them are discussed in detail. Each operative step is illustrated superbly and accompanied by a short, precise text. Both illustrations and text stem from the practical experience in the operating theater of the many renowned surgeons who have contributed to this volume. The book serves as an indispensable reference for surgeons; likewise, gastroenterologists, radiologists, pathologists, and anatomists will find this volume of immeasurable value in their daily work.

Shoulder Arthroscopy and MRI Techniques is an authoritative text on the various techniques in arthroscopic surgery of the shoulder joint. International experts in the field cover the whole spectrum of the state of the art. Clear and self-explanatory illustrations depict the operative procedures in a step-by-step manner. The authors communicate tips and tricks, thus enabling the reader to easily reproduce the procedures with the desired results. Through direct comparison between arthroscopic and MRI photographs the surgeon will be able to correlate the two and draw important conclusions. Another focus is placed on post-operative MRI evaluation. The reader is provided with up-to-date information and a valuable guide in his daily routine.

Diagnostic neuroradiology is undergoing such rapid change that standard texts are quickly becoming outdated in important respects. Recent Advances in Diagnostic Neuroradiology is designed to complement the general textbooks of neuroradiology by documenting and discussing the progress that has been achieved. Following six introductory chapters, 26 important topics in brain and spinal imaging are discussed in detail, with appropriate illustrations and a review of the most recent literature. Each of these topics has specifically been chosen in order to summarize recent developments and to document the state of the art in the field. This book, written by acknowledged experts in the field, will be of relevance and importance to all with an interest in neuroradiology.

Whereas during the past decade endoscopy has become established as the leading means of diagnosis and management of diseases affecting the esophagus, starnach and large bowel, radiology has retained its pre-eminence for the clinical study and evaluation of the small bowel. This book provides unique coverage of all current radiological techniques used to study the small bowel, including not only barium studies and angiography but also cross-sectional methods such as uhrasound and computer tomography as well as nuclear medicine. Ernerging techniques such as magnetic resonance imaging are given close consideration, and interventional procedures are dealt with fully. Following an introduction on anatomy, physiology, and pathology pertinent to radiol ogy, the book describes in great detail common and less common congenital and development anomalies, trauma, infectious and infl.ammatory conditions, and tumors. The radiological accounts are illustrated by unique color photographs of pathological specimens. It is important for all professionals involved in the management of patients with small-bowel disease tobe critically informed about the specific advantages as well as the limitations of the various modern imaging techniques now employed for the in vivo morphological evaluation of the small bowel. This comprehensive book provides a timely update of our knowledge in this field and is a welcome addition to our series "Medical Radiology;' which aims to provide exhaustive coverage of modern diagnostic radiology. It will be of great interest for general and abdominal radiologists, gastroen terologists, and abdominal surgeons.

The current textbooks for specialists are too detailed. This book will be a handy pocket guide for trainee vascular radiologists, and will serve as an aide-memoire for senior vascular radiologists. Each procedure will be shown in its entirety. Rather than being a library purchase, this book will be a handy and accessible guide for quick reference aimed at clinical interventional radiologists in multidisciplinary staff rooms and angiography suites.

This second edition is adheres to the guiding principles of the first edition while serving as a useful and up to date manual on the theory, performance and application of CCTA. Since the publication of the first edition of this work, cardiac CT angiography (CCTA) has come a long way. It is now a main stream, well established cardiac diagnostic imaging modality with wide spread acceptance and application.

Stroke remains one of the main causes of death and disability worldwide. While effective therapy for stroke recovery remains an unmet need. Much hope and promises are placed on cell-based therapies. The aim of this book is to provide focused yet comprehensive reviews on the current state of cell-based approaches in the treatment of stroke. The topics covered include experimental data on functional outcome after intravascular and intracerebral delivery of cells in stroke animals, followed by translational chapters which will rely heavily on the use of different imaging modalities in the tracking of cells. The last and most challenging part will describe the early phase of clinical studies, providing guidelines for future research and clinical applications. Clearly and concisely written, this text will be a useful resource for neurologists, radiologists, and neuroscientists interested in cell transplantation as a therapeutic strategy for stroke patients.

This book is based on contributions presented at the 1st World Congress on Gallium-68 and Peptide Receptor Radionuclide Therapy, which examined recent developments in theranostics - the emerging field of molecular targeting of vectors that can be used for both diagnosis and therapy, when modified accordingly. The focus of this book is on the rapidly developing research into and clinical applications of gallium-68 and other generator-produced PET radionuclides in the personalized diagnosis and treatment of neuroendocrine tumors and other diseases. In addition, new PET radiopharmaceuticals are considered, and the latest ideas and concepts, presented. Theranostics embodies both molecular and personalized medicine. It is at the cutting edge of medicine, and the contents of this volume will be of interest to chemists, physicians, and investigators dealing with generators, PET radiochemistry, molecular imaging, and radionuclide therapy.

In 194 cases featuring over 450, high-quality images, Nuclear Medicine and PET/CT Cases provides a succinct review of clinically relevant cases covering the full range of nuclear medicine. Cases are grouped into sections including: Nuclear CNS Imaging, Nuclear Inflammation/Infection Imaging, Ventilation/Perfusion Lung Scintigraphy, Pediatric Nuclear Medicine, Cardiac Imaging, Bone Scintigraphy, PET/CT in Oncology, General Oncologic Imaging, Thyroid and Parathyroid, Radionuclide Therapy and Pre-Therapy Evaluation, Liver, Spleen and Biliary Tract, Gastrointestinal Tract, Renal Scintigraphy. Part of the Cases in Radiology series, this book follows the easy-to-use format of question and answer in which the patient history is provided on the first page of the case, and radiologic findings, differential diagnosis, teaching points, next steps in management, and suggestions for furthering reading are revealed on the following page. This casebook is an essential resource for radiology residents and practicing radiologists alike.

This foreword deals exclusively with the planning, organization, and execution of the Workshop's scientific as well as cultural programs. It is opened with a synopsis on how the global political changes that occurred immediately after the Workshop caused the ~elay in producing the proceedings, followed by a brief exposition on need, timeliness, and importance of this second ARW in the field of electromagnetic imaging, radar remote sensing, and target versus clutter di~rimination; and an outline of the objectives. An informal discussion about some of the organizational details, a retrospective summary of events, and a preview of the third workshop, planned for 1993 September 19-25, is intended to recapture the spirit of this second NATO Advanced Research Workshop (1988 September 18-24), and will reveal how successful it was in compar ison to the first of 1983 September 18-24, how its accomplishments may be appreciated and why a third and last workshop was requested by its participants to take place during 1993 September 19-25.

In 129 cases featuring over 600, high-quality images, Genitourinary Imaging Cases provides a succinct review of clinically relevant cases which cover both benign and malignant conditions of the genitourinary system. Cases are grouped into sections that are organized by body part including: Kidney, Retroperitoneum, Adrenal, Ureter, Bladder, Prostate, Urethra, Vagina, Penis, Testis, Epididymis, and Scrotum, Uterus and Fallopian Tube, and Ovary. Part of the Cases in Radiology series, this book follows the easy-to-use format of question and answer in which the patient history is provided on the first page of the case, and radiologic findings, differential diagnosis, teaching points, next steps in management, and suggestions for furthering reading are revealed on the following page. This casebook is an essential resource for Radiology Residents and practicing Radiologists alike.

- Donation refusal is high in all the regions of Argentina. - The deficient operative structure is a negative reality that allows inadequate donor maintenance and organ procurement. - In more developed regions, there are a high number of organs which are not utilized. This is true for heart, liver and lungs. Small waiting lists for these organs probably reflect an inadequate economic coverage for these organ transplant activities. - There is a long waiting list for cadaveric kidney transplants, which reflect poor procurement and transplant activity. - Lack of awareness by many physicians leads to the denouncing of brain deaths. In spite of these factors, we can say that there has been a significant growth in organ procuration and transplantation in 1993, after the regionalization of the INCUCAI. Conclusions Is there a shortage of organs in Argentina? There may be. But the situation in Argentina differs from that in Europe, as we have a pool of organs which are not utilized (donation refusal, operational deficits, lack of denouncing of brain deaths). Perhaps, in the future, when we are able to make good use of all the organs submitted for transplantation, we will be able to say objectively whether the number of organs is sufficient or not. Acknowledgements I would like to thank the University of Lyon and the Merieux Foundation, especially Professors Traeger, Touraine and Dr. Dupuy for the honour of being invited to talk about the issue of organ procurement.

The author describes in his unique style the anatomical variants of the brain and skull. This atlas is a continuation of his last work on "Neuronavigation and Neuroanatomy". Most anatomical reference volumes show a large number of common and rare variations. This atlas concentrates on well known and little known variants which are especially important for the clinicians, in particular the neurosurgeons and the radiologists. The variants have been grouped after areas of trepanation. The author presents also a number of so far unknown variants gathered from his personal theoretical and clinical experience of 50 years. Exact knowledge of anatomical variations which the surgeon may encounter helps to plan operations and to avoid unexpected complications. Variants of no clinical relevance, even rather common ones, have not been included.

The study of bone cells and tissues at the cellular and molecular levels in a variety of models has revolutionized the field. In this book, leading scientists from around the world share their step-by-step laboratory protocols for studying bone biology. This is the perfect guide for both new and experienced experimentalists attempting to study osteoporosis.

This book was born out of thirty years of didactic and practical experience with the intention of giving the reader concise neurosurgical elements and an appropriate selected iconography. This text wants to represent a practi cal and essential guide for the medical student and a useful reference point for specialists interested in pursuing more detailed literature studies. General practitioners and specialists in related subjects can consult this text to formulate a diagnosis and elaborate a proper therapy. November, 2000 The Authors Contents 1. CRANIAL DYSRAPHIAS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Arnold-Chiari malformation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Dandy-Walker malformation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Encephalocele . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Cranial dermic sinus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 Corpus callosum agenesis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 2. BRAIN TUMORS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Epidemiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Symptoms and signs. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Intracranial hypertension. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Focal symptoms and signs. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 Epilepsy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 Language disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Optic pathways disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 Apraxias. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 Psychic disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 Cerebellar syndrome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 Frontal lobe tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 Parietal lobe tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 Temporal lobe tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 Occipital lobe tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 Posterior cranial fossa tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Cerebellar tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Fourth ventricle tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 Ponto-cerebellar angle tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 VIII Contents Brainstem tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Clivus tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Tumors of the cerebral ventricles. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 Tumors of the lateral ventricles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 Third ventricle tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 Fourth ventricle tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 Pineal region tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 Sellar and parasellar region tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 Anatomopathological classification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 Benign cerebral tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 Leptomeningeal tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 Nerve sheath tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 Vascular tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 Dysembryogenetic tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 Mixed cerebral tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 Malignant cerebral tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 Therapy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 Pseudo tumor cerebri . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56 Phacomatosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56 3. INTRACRANIAL ANEURySMS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . S9 Epidemiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Methods of nuclear magnetic resonance (NMR) are increasingly applied in engineering sciences. The book summarizes research in the field of chemical and process engineering performed at the Karlsruhe Institute of Technology (KIT). Fundamentals of the methods are exposed for readers with an engineering background. Applications cover the fields of mechanical process engineering (filtration, solid-liquid separation, powder mixing, rheometry), chemical process engineering (trickle-bed reactor, ceramic sponges), bioprocess engineering (biofilm growth), and food process engineering (microwave heating, emulsions). Magnetic Resonance Imaging (MRI) as well as low-field NMR are covered with notes on hardware. Emphasis is placed on quantitative data analysis and image processing.

Modern Oncology, first published in 2001, offers a concise and accessible guide to the key terms in oncology, defining essential terminology and important concepts in a didactic and highly readable style for a wide audience. Extensive use is made throughout of cross-referencing, to aid rapid access to topics of interest and the broad coverage includes such subjects as physics, radiation biology, clinical pharmacology, statistics and clinical epidemiology, tumour biology and molecular biology. Wherever possible, clinically relevant examples and real-world data are included to help the trainee or busy clinician to quickly place their findings in a broad clinical context. The book will be an essential tool to any healthcare professional with a need to understand oncology when seeing patients, reading medical reports or interpreting scientific papers.

In recent years, developments in ultrasound, computed tomography and magnetic resonance imaging have made important changes in the practice of diagnostic radio logy. Concomitantly, invasive radiology for both diagnostic and therapeutic purposes has grown into a rapidly evolving subspecialty. This text represents a landmark in paediatric radiology. The three authors are distinguished radiologists who, over the past two decades, have greatly contributed to paediatric hepatology. Their pioneering work in the area of splanchnic angiography and diagnostic as well as therapeutic cholangiography was facilitated by their close day-to-day interaction with the Paediatric Liver Disease Unit at Hoepital Bicetre. The contents and the format of this "atlas" are testimony to their knowledge of clinical hepatology and to their wide experience in invasive paediatric radiology. The out standing quality of the images is enhanced by appropriate clinical descriptions which will help the reader understand the indications for these procedures, their accuracy and limitations.

In recent years, revolutionary technical advances have permitted neuroscientists to map the functioning of the brain in exquisite detail. Of interest are the new techniques that visually display cell energy metabolism which is coupled to functional brain activity in behaving animals. This is the first book dealing with the application of 2-deoxyglucose and related metabolic mapping techniques for brain imaging of behavioral and learning functions. Quantitative autoradiographic techniques based on the use of exogenous markers include radiolabeled glucose and its analogs, especially 2-deoxyglucose and fluorodeoxyglucose. Other mapping techniques are based on the histochemical staining of endogenous metabolic markers such as cytochrome oxidase, as well as immunohistochemistry for expression of c-fos genes. In spite of the great potential capabilities of the new imaging techniques, relatively few neuroscientists are using this approach to study brain functions related to behavior. There is a need to review state-of-the-art applications of these methods in behavioral neuroscience, and to formulate recommendations for future research in this area. This book is intended to fulfill these needs by bringing together leading neuroscientists using metabolic mapping approaches to elucidate brain mechanisms of behavior. Discussions are not limited to one animal species, but they cover a broad range of vertebrates with unique behavioral capabilities.

Percutaneous nuclectomy according to the Onik method is an avantgarde method used to remove the intervertebral disc by percutaneous access and with closed surgery. The instrumentation and the procedure are simple. The main feature is the smaller diameter of the probe (2mm) which fragments and aspires the small chips of pulpy nucleus. It reduces the risk of discitic infections (occurring in various percentages with all methods of percutaneous discectomy) because the hole in the anulus, being small, closes spontaneously after the probe is removed. Moreover postoperative acute lumbar pain has been reported to occur less frequently. This method is carried out under local anesthesia, with radioscopic and intraoperative discographic monitoring. By consulting this atlas orthopaedists, neurosurgeons and neuroradiologists may learn this method easily, because every detail is clearly presented and illustrated with a great number of coloured pictures.

This book summarizes the proceedings of the 10th international conference on Infonnation Pro cessing in Medical Imaging (IPMI-lO), held in June, 1987, in Zeist, The Netherlands. IPMI is a biennial conference, organized alternately in Europe and North America. The subject of the conference is the use of physics, mathematics, computer science, and engineering in the of medical images. The intent of the conference is to fonnation, processing and interpretation provide a forum where new ideas and results of research in medical imaging can be presented and amply discussed. Accordingly, the programme can comprise only a limited number of papers. The scientific committee of IPMI-lO selected 41 papers for presentation, although a total of 102 extended abstracts of on the average high quality had been submitted. All selected contri butions are included in these proceedings. During of the preparations of the conference the organizers received the tragic news of the death of Francois Erbsmann, the initiator of IPMI, and organizer of the first conference in 1969 in Brussels. Francois always emphasized that the backbone of the IPMI meetings should be promising young and active researchers rather than established scientists in the field. As an appreciation of this idea, and in thankful remembrance of Francois' stimulating work, the IPMI-board has taken the initiative to present the Francois Erbsmann prize for the most significant contribution to the conference by a young investigator.

This book provides an easy-to-use manual that will help trainee and practising interventional radiologists by providing cases which cover most of the complications that a general interventionalist may encounter in normal practice. There will be 40-50 cases. The cases will be presented succinctly but thoroughly, such that the reader is equipped to manage the complication immediately. At least 50% of cases will be from District General Hospital Consultants.

The Practice of Interventional Radiology, by Dr. Karim Valji, presents a comprehensive approach to help you master the latest techniques. Online case studies teach you a wide range of interventional techniques, such as chemoembolization of tumors, venous access, angioplasty and stenting, and much more. With coverage of neurointerventional procedures, image-guided non-vascular and vascular procedures, and interventional oncologic procedures - plus access to the full text, case studies, images, and videos online at www.expertconsult.com - you'll have everything you need to offer more patients a safer alternative to open surgery. Presents the entire spectrum of vascular and nonvascular image-guided interventional procedures in a rigorous but practical, concise, and balanced fashion. Stay current on the latest developments in interventional radiology including neurointerventional procedures, image-guided non-vascular and vascular procedures, and interventional oncologic procedures. Learn the tenets of disease pathology, patient care, techniques and expected outcomes, and the relative merits of various treatment modalities. Find everything you need quickly and easily with consistent chapters that include patient cases, normal and variant anatomy, techniques, and complications. Master procedures and recognize diseases through over 100 case studies available online, which include images and interactive Q&A to test your knowledge; Online videos that demonstrate basic and expert-level interventional techniques. Access the fully searchable text at www.expertconsult.com, along with over 100 cases, 1500 corresponding images, and videos. Enhance your skills in interventional radiology and reduce patient risk

New imaging technology and more sophisticated image processing systems will have a profound effect on those areas of medicine which are concerned with imaging for diagnosis and therapy planning. Digitally formated data will form the basis of an increasing number of medical imaging modalities. Before the diagnostic imaging department of the future will largely be digital, many problems have still to be solved as regards image quality, costs, and ease of use. The computer and other information science derived methods will contribute towards solving many of the problems in these areas. It is widely expected that there will be an information science derived evolution in imaging for radiology and related departments. Computer assistance may be applied to image generation, e.g. CT, MRI, DR and DSR, storing and transferring of images, and viewing, analysing and interpreting of images. The application of computers to these activities (which characterise radiological departments), may be defined as Computer Assisted Radiology (CAR) . In the main, CAR will promote the transition from analog imaging systems to digital systems, integration of digital imaging modalities through Picture Archiving and Communication Systems (PACS') and the graduated employment of Medica~ Work Stations (MWS) for diagnosis and therapy planning. It will transfer geographically, organisationally and/or mentally isolate imaging activities towards fully integrated multi-imaging modality diagnostic departments. This development will have a considerable impact on patient management, on the medical profession and on the health care system.

Magnetic resonance spectroscopy (MRS) is a modality available on most clinical MR scanners and readily integrated with standard MR imaging (MRI). For the brain in particular, MRS has been a powerful research tool providing additional clinically relevant information for several disease families such as brain tumors, metabolic disorders, and systemic diseases. The most widely-available MRS method, proton (1H; hydrogen) spectroscopy, is FDA approved for general use in the US and can be ordered by clinicians for patient studies if indicated. There are several books available that describe applications of MRS in adults. However, to the best of our knowledge there is currently no book available that focuses exclusively on applications in pediatrics. MR spectroscopy in the pediatric population is different from adults for two main reasons. Particularly in the newborn phase the brain undergoes biochemical maturation with dramatic changes of the "normal" biochemical fingerprint. Secondly, brain diseases in the pediatric population are different from adult disorders. For example, brain tumors, which are mostly gliomas in the adults, often originate from different cell types and are also more diverse even within the same type and grade of tumor. This diversity of diseases and its implications for MR spectroscopy has not been addressed sufficiently in the literature, we believe. The target audience for "MR Spectroscopy of Pediatric Brain Disorders" are thus both clinicians and researchers involved with pediatric brain disorders. This includes radiologists, neurologists, neurooncologists, neurosurgeons, and more broadly the neuroscience and neurobiology community. This book will provide the necessary background information to understand the basics of MR spectroscopy. This will be followed by a detailed discussion of the normal biochemical maturation which will highlight the metabolic differences between the pediatric and adult brain. Thereafter, in SECTION I individual chapters will address various pediatric brain disease families. Of particular importance for pediatrics are case studies. For that reason, SECTION II will contain a large number of case studies. This will be particularly important for clinicians who may want to see examples of MRS for various conditions. A standardized format will be used for case reports that allow the reader to quickly understand the history of each case presented and the significance of the findings. The case reports will also include information from other imaging modalities to point out any added value of MRS in addition to conventional studies and clinical information. This section is necessary because the format of providing more complete information about individual patients is not practical for the chapters in SECTION I.