This book critically assesses the current state of knowledge on new and important detection technologies, e.g. mass spectrometry, tandem mass spectrometry, biosensor detection and tissue imaging, in connection with toxic chemical and biological agents. In general, the main topics discussed concern the risks and consequences of chemical and biological agents for human health in general, with special emphasis on all biochemical and metabolic pathways including the reproductive system. The exposome, genetic risks and the environment, various health hazard agents, risk assessment, environmental assessment and preparedness, and analysis of sub-lethal effects at the molecular level are also discussed. In closing, the book provides comprehensive information on the diagnosis of exposure, and on health concerns related to toxic chemical and biological agents.

This book provides an up-to-date overview of gastrointestinal malignancies, including prevention, early detection, intervention, and life-extending therapeutics. It also assesses various biomarkers used for diagnostics, prognostics and prediction of response to chemoresistance. Further, it discusses the latest trends in the use of small-molecule targeted therapies and immunotherapies as single agents or combination with other treatments. Since resistance to radiation and chemotherapy contribute to the high recurrence and poor survival rates, improving the outcome for GI malignancies is dependent on the introduction of new biomarkers and therapeutic agents. Lastly, the book systematically investigates novel theranostics approaches using nanotechnology for the detection, diagnosis, and personalized treatment of GI malignancies.

This book provides an in-depth description and discussion of different multi-modal diagnostic techniques for cancer detection and treatment using exact optical methods, their comparison, and combination. Coverage includes detailed descriptions of modern state of design for novel methods of optical non-invasive cancer diagnostics; multi-modal methods for earlier cancer diagnostic enhancing the probability of effective cancer treatment; modern clinical trials with novel methods of clinical cancer diagnostics; medical and technical aspects of clinical cancer diagnostics, and long-term monitoring. Biomedical engineers, cancer researchers, and scientists will find the book to be an invaluable resource. Introduces optical imaging strategies; Focuses on multimodal optical diagnostics as a fundamental approach; Discusses novel methods of optical non-invasive cancer diagnostics.

This book provides an essential overview of the broad range of functional brain imaging techniques, as well as neuroscientific methods suitable for various scientific tasks in fundamental and clinical neuroscience. It also shares information on novel methods in computational neuroscience, mathematical algorithms, image processing, and applications to neuroscience. The mammalian brain is a huge and complex network that consists of billions of neural and glial cells. Decoding how information is represented and processed by this neural network requires the ability to monitor the dynamics of large numbers of neurons at high temporal and spatial resolution over a large part of the brain. Functional brain optical imaging has seen more than thirty years of intensive development. Current light-using methods provide good sensitivity to functional changes through intrinsic contrast and are rapidly exploiting the growing availability of exogenous fluorescence probes. In addition, various types of functional brain optical imaging are now being used to reveal the brain's microanatomy and physiology.

Chiropractic Radiography and Quality Assurance Handbook is the first book devoted to erect and recumbent radiographic positioning and a practical approach to quality assurance and radiographic quality control testing. It provides a step-by-step approach to performing quality radiographic studies using radiographic images to demonstrate placement of anatomical markers and the safest location for patient identification information.
Some topics covered include:
o The importance of sound radiation safety practices and appropriate protection and collimation
o Spinal radiography including changes in positioning to reduce exposure to female patients
o Extremity radiography, covering common and specialty views to assist in diagnosis of sports injuries.
Designed for both the practitioner and the student, this book provides all of the tools necessary to produce quality radiographs in a quick reference, detailed, step-by-step approach to positioning. And adding information about darkroom and film storage, film processing quality control, film artifact identification and problem solving, makes this is an in-depth, authoritative guide.

This book takes account of recent changes in the Fellowship of the Royal College of Radiologists (FRCR) Part 2A examination. It includes basic radiological science questions as well as the original clinical imaging component, and in particular it discusses cross sectional imaging at an advanced level. Many of these questions are also very useful in preparation for the American Boards Exam in Radiology. Unlike other books in this field, this essential guide provides full explanatory answers and bibliography. Questions are divided into subject chapters corresponding to those in the current FRCR Part 2A syllabus, and structured in an identical fashion to the actual exam.

Demonstrating the role of nuclear medicine as a complementary technique to mammography and other imaging modalities for the diagnosis of breast cancer, Radionuclide Imaging of the Breast provides a comprehensive overview of scintimammography-an accurate, safe, and noninvasive imaging method for the evaluation of breast lesions and malignancies. Reveals the encouraging results of multicenter clinical trials in the U.S. and Canada using 99mTc sestamibi breast imaging for the diagnosis of primary breast carcinoma! Addressing nonsurgical sampling of nonpalpable breast lesions as an effective means of providing diagnostic and prognostic information, Radionuclide Imaging of the Breast -discusses increasing the diagnostic value of mammography and its widespread use -examines the reliability of FDG-PET and FDG-SPECT in detecting lymph node involvement and distant metastases -reviews breast cancer imaging with monoclonal antibodies, including murine and bioengineered antibodies -compares the benefits and limitations of Thallium-20l to 99mTc-sestamibi breast imaging in evaluating suspected malignancy -assesses the clinical impact of scintimammography as an adjunctive test to mammography to improve the dependability of diagnoses -considers the possibility of replacing axillary lymph node dissection in patients with small breast cancers with the sentinel node approach -clarifies the importance of surgery in the multimodality treatment of breast cancer -elucidates pathologic difficulties for breast cancer diagnosis -and more! Radionuclide Imaging of the Breast serves as an essential reference for nuclear medicine physicians, radiologists, breast surgeons, medical and surgical oncologists, gynecologists, pathologists, internists, and primary care physicians.

This book covers virtually all aspects of image formation in medical imaging, including systems based on ionizing radiation (x-rays, gamma rays) and non-ionizing techniques (ultrasound, optical, thermal, magnetic resonance, and magnetic particle imaging) alike. In addition, it discusses the development and application of computer-aided detection and diagnosis (CAD) systems in medical imaging. Given its coverage, the book provides both a forum and valuable resource for researchers involved in image formation, experimental methods, image performance, segmentation, pattern recognition, feature extraction, classifier design, machine learning / deep learning, radiomics, CAD workstation design, human-computer interaction, databases, and performance evaluation.

This book describes and illustrates an approach to surgery for spinal cord tumors that is based on a refined concept of anatomic compartmentalization. The aim of this approach is to enable maximum preservation of spinal cord function through confinement of the surgical work to the involved compartment or compartments. Importantly, this involvement differs according to tumor type, and the classification favored by the author takes this fully into account. After introductory chapters on epidemiology and pathology, the anatomy of the spinal cord relevant to surgery for spinal cord tumors is discussed in detail and the proposed classification is clearly explained. The surgical approach to each of the identified anatomic compartments is then described, with attention to the roles of intraoperative mapping techniques, diffusion tensor imaging, and electrophysiologic studies in ensuring that spinal cord functions are spared. Examples of the author's experience when applying the proposed approach are presented. The book is meant for neurosurgeons at all levels of experience.

This book illustrates 100 classic radiologic signs with radiograms alongside illustrative photographs for memory aids and clarification. Accompanying text explains the history and meaning of the descriptive name. The entry for "dromedary hump," for example, shows a typical x-ray of this condition with a photograph of a dromedary camel that clearly shows how the name fits the sign. Dr. Mulligan says, "In honor of the 100th anniversary of Roentgen's discovery, this book illustrates and elaborates on the history of 100 of the more classic radiologic signs. If we are to use these terms with full understanding, we must have the ability to visualize the object depicted by the term, imagine its radiographic appearance, and transfer that picture to the radiographic image before us. This book is intended to help practitioners and students of our art accomplish that task."

This third edition overviews the essential contemporary topics of neuroengineering, from basic principles to the state-of-the-art, and is written by leading scholars in the field. The book covers neural bioelectrical measurements and sensors, EEG signal processing, brain-computer interfaces, implantable and transcranial neuromodulation, peripheral neural interfacing, neuroimaging, neural modelling, neural circuits and system identification, retinal bioengineering and prosthetics, and neural tissue engineering. Each chapter is followed by homework questions intended for classroom use. This is an ideal textbook for students at the graduate and advanced undergraduate level as well as academics, biomedical engineers, neuroscientists, neurophysiologists, and industry professionals seeking to learn the latest developments in this emerging field.Advance Praise for Neural Engineering, 3rd Edition: "A comprehensive and timely contribution to the ever growing field of neural engineering. Bin He's edited volume provides chapters that cover both the fundamentals and state-of-the-art developments by the world's leading neural engineers." Dr. Paul Sajda, Department of Biomedical Engineering, Electrical Engineering and Radiology, Columbia University "Neural Engineering, edited by Prof. He, is an outstanding book for students entering into this fast evolving field as well as experienced researchers. Its didactic and comprehensive style, with each chapter authored by leading scientific authorities, provides the ultimate reference for the field." Dr. Dario Farina, Department of Bioengineering, Imperial College London, London, UK "Neural Engineering has come of age. Major advances have made possible prosthesis for the blind, mind control for quadraplegics and direct intervention to control seizures in epilepsy patients. Neural Engineering brings together reviews by leading researchers in this flourishing field. Dr. Terrence Sejnowski, Salk Institute for Biolgical Studies and UC San Diego

This popular text provides a comprehensive, yet accessible, introduction to the physics and technology of medical ultrasound, with high quality ultrasound images and diagrams throughout. Covering all aspects of the field at a level that meetings the requirements of accredited sonography courses, it is ideal for both trainee and qualified healthcare professionals practising ultrasound in a clinical setting. Building on the content of previous editions, this third edition provides the latest guidance relating to ultrasound technology, quality assurance and safety and discusses the latest techniques.

This handbook presents the most current information on the effects of ionizing radiation on mammalian cells, with emphasis on human tissues. The dose-effect relationship is emphasized in a quantitative manner. The book contains up-to-date data on the late effects of low levels of radiation on humans. It also provides some of the late consequences of radiation therapy detected among cancer survivors.

This book comprehensively reviews the recent advances in nanomaterial-based molecular imaging, diagnostics, and personalized therapy. It discusses the novel biocompatible fluorescent nanomaterials, their synthesis, and modern state of art characterization, as well as the various strategies for immobilization of biomacromolecules on the nanomaterial surface and approaches for increasing their stability. In addition, the book describes the synthesis of lectin nanoconjugates using different types of biocompatible raw materials and their systematic characterization. Lastly, it presents our current understanding of the biomolecular carona, which affects nanoparticle-based targeted drug delivery, and examines the conceptual approaches to improve the in-vivo efficacy of targeted drug delivery.

This book covers emerging trends in signal processing research and biomedical engineering, exploring the ways in which signal processing plays a vital role in applications ranging from medical electronics to data mining of electronic medical records. Topics covered include statistical modeling of electroencephalograph data for predicting or detecting seizure, stroke, or Parkinson's; machine learning methods and their application to biomedical problems, which is often poorly understood, even within the scientific community; signal analysis; medical imaging; and machine learning, data mining, and classification. The book features tutorials and examples of successful applications that will appeal to a wide range of professionals and researchers interested in applications of signal processing, medicine, and biology.

Editor Savvas Nicolaou, MD and authors provide a comprehensive review of Emergency and Trauma Radiology. Articles will include: Improving outcomes in the polytrauma patient: a review of the role of whole body CT; Advanced imaging in the emergency department: dual energy CT in the acute setting; Imaging of traumatic brain injury: basic concepts and future direction; Imaging patterns and management algorithms in acute stroke: an update for the emergency radiologist; Imaging of non-traumatic neuroradiology emergencies; Pearls and pitfalls in C-spine trauma with new concepts; Face and neck infections: What the emergency radiologist needs to know; Negative CT for acute pulmonary embolism: important differentials in acute dyspnea; Imaging of penetrating thoracic injury; Imaging of easily missed fractures in the upper extremity; Imaging of easily missed fractures in the lower extremity; Imaging of genitourinary trauma; Imaging of ischemia, obstruction and infection in the abdomen; Imaging of pancreatic and duodenal trauma; and more!

Teleradiologische Befundung wird immer wichtiger fur Kliniken, die sich nachts und Feiertags keinen Radiologen leisten koennen oder wollen. Mit der immer populareren Telemedizin ist auch die Teleradiologie seit Jahren immer mehr gewachsen. Ziel des Buches ist es, umfassend uber das teleradiologische Arbeiten, die Moeglichkeiten, Arbeitsablaufe, Infrastruktur und Anwendungsbereiche zu informieren. Dabei wird sowohl die Anwenderseite (der radiologische Arzt als Befunder) als auch die Auftraggeber-Seite (die Kliniken) beleuchtet, die hier eng verzahnt interagieren mussen. Inhalte: Das Buch informiert den Leser umfassend uber die folgenden Aspekten der Teleradiologie AErztliche Aspekte Sicht des Krankenhaus-Managements, gesetzliche Vorgaben (Strahlenschutzgesetz und -verordnung), DIN-Normen, Arbeitsablaufe, Genehmigungsprozess, Qualitatsaspekte, Integration in die IT-Landschaft der Beteiligten, Kommunikationsstandards in der Medizin/Radiologie, Beispiele realisierter Teleradiologie-Netzwerke, Datenschutz und Rechtsfragen .

Pass the AART advanced level mammography certification exam with this peerless guide packed with 450+ practice questions, answer explanations, and high-quality visuals LANGE Q&A: Mammography, Fifth Edition makes the ARRT study process easy and efficient by focusing only on what readers really need to know. A complete study tool for anyone working towards ARRT certification, this peerless guide offers the information and insights you need to build your knowledge-and confidence-to ensure peak performance on exam day. High-quality illustrations, including radiographs, detail various types of lesions such as benign and malignant calcifications, enable image comparison, and illustrate pathology. Here's why LANGE Q&A: Mammography is the ultimate review for the ARRT Advance Level Mammography Certification Exam: * Updated to reflect the latest ARRT mammography exam blueprint * 250+ chapter-ending questions assure readers understand the material and are ready for test day * Illustrations and figures highlight/summarize important information * Covers the latest 3D digital technologies * Written by an experienced radiography instructor who knows exactly what it takes to pass

This book provides a broad overview of pancreatic neuroendocrine neoplasms, focusing on the most important developments in the technologies used to diagnose, classify and treat them. After a historical and epidemiological overview, the opening chapters examine the various diagnostic approaches (radiology, nuclear medicine, endocrinology, cytology and immunohistochemistry) and discuss the WHO classification. The functioning and nonfunctioning tumor types are then fully discussed, covering epidemiology, diagnosis, morphology and prognosis of each entity. Careful consideration is given to the molecular features that have contributed in understanding the pathogenesis of such neoplasms and may have potential implications for the diagnostic and therapeutic pathways. The final chapters consider the surgical and medical approaches to therapy, providing a practical and analytical overview of the available options. The book is written by a multidisciplinary team of worldwide-recognized experts and is addressed to radiologists, nuclear medicine physicians, endocrinologists, pathologists, surgeons and oncologists.

Computational Biomechanics for Medicine: Solid and fluid mechanics for the benefit of patients contributions and papers from the MICCAI Computational Biomechanics for Medicine Workshop help in conjunction with Medical Image Computing and Computer Assisted Intervention conference (MICCAI 2019) in Shenzhen, China. The content is dedicated to research in the field of methods and applications of computational biomechanics to medical image analysis, image-guided surgery, surgical simulation, surgical intervention planning, disease prognosis and diagnostics, analysis of injury mechanisms, implant and prostheses design, as well as artificial organ design and medical robotics. These proceedings appeal to researchers, students and professionals in the field.

Musculoskeletal Imaging Volume 2 provides a comprehensive review of the subject matter commonly encountered by practicing radiologists and radiology residents in training. This volume includes succinct overviews of metabolic, infectious, and congenital diseases; internal derangement of joints; and arthography, and ultrasound. Part of the Rotations in Radiology series, this book offers a guided approach to imaging diagnosis with examples of all imaging modalities complimented by the basics of interpretation and technique and the nuances necessary to arrive at the best diagnosis. Each pathology is covered with a targeted discussion that reviews the definition, clinical features, anatomy and physiology, imaging techniques, differential diagnosis, clinical issues, key points, and further reading. This organization is ideal for trainees' use during specific rotations, for exam review, or as a quick refresher for the established musculoskeletal imager. It is a must-read for residents and practicing radiologists seeking a foundation for the essential knowledge base in musculoskeletal imaging. Musculoskeletal Imaging Volume 1 reviews trauma, arthritis, and tumor and tumor-like conditions.

This book presents non-linear image enhancement approaches to mammograms as a robust computer-aided analysis solution for the early detection of breast cancer, and provides a compendium of non-linear mammogram enhancement approaches: from the fundamentals to research challenges, practical implementations, validation, and advances in applications. The book includes a comprehensive discussion on breast cancer, mammography, breast anomalies, and computer-aided analysis of mammograms. It also addresses fundamental concepts of mammogram enhancement and associated challenges, and features a detailed review of various state-of-the-art approaches to the enhancement of mammographic images and emerging research gaps. Given its scope, the book offers a valuable asset for radiologists and medical experts (oncologists), as mammogram visualization can enhance the precision of their diagnostic analyses; and for researchers and engineers, as the analysis of non-linear filters is one of the most challenging research domains in image processing.

From the essential background physics and radiobiology to the latest imaging and treatment modalities, the updated second edition of Handbook of Radiotherapy Physics: Theory & Practice covers all aspects of the subject. In Volume 1, Part A includes the Interaction of Radiation with Matter (charged particles and photons) and the Fundamentals of Dosimetry with an extensive section on small-field physics. Part B covers Radiobiology with increased emphasis on hypofractionation. Part C describes Equipment for Imaging and Therapy including MR-guided linear accelerators. Part D on Dose Measurement includes chapters on ionisation chambers, solid-state detectors, film and gels, as well as a detailed description and explanation of Codes of Practice for Reference Dose Determination including detector correction factors in small fields. Part E describes the properties of Clinical (external) Beams. The various methods (or 'algorithms') for Computing Doses in Patients irradiated by photon, electron and proton beams are described in Part F with increased emphasis on Monte-Carlo-based and grid-based deterministic algorithms. In Volume 2, Part G covers all aspects of Treatment Planning including CT-, MR- and Radionuclide-based patient imaging, Intensity-Modulated Photon Beams, Electron and Proton Beams, Stereotactic and Total Body Irradiation and the use of the dosimetric and radiobiological metrics TCP and NTCP for plan evaluation and optimisation. Quality Assurance fundamentals with application to equipment and processes are covered in Part H. Radionuclides, equipment and methods for Brachytherapy and Targeted Molecular Therapy are covered in Parts I and J, respectively. Finally, Part K is devoted to Radiation Protection of the public, staff and patients. Extensive tables of Physical Constants, Photon, Electron and Proton Interaction data, and typical Photon Beam and Radionuclide data are given in Part L. Edited by recognised authorities in the field, with individual chapters written by renowned specialists, this second edition of Handbook of Radiotherapy Physics provides the essential up-to-date theoretical and practical knowledge to deliver safe and effective radiotherapy. It will be of interest to clinical and research medical physicists, radiation oncologists, radiation technologists, PhD and Master's students.

Sharpen your skills in chest x-ray interpretation using this trusted clinical resource! Chest Radiology: Patterns and Differential Diagnoses, 7th Edition, by Dr. James Reed, walks you through a logical, sequential thought process for the differential diagnoses of 23 radiologic patterns of common chest diseases, using 150 superbly illustrated patient cases. You'll gain a solid and thorough understanding of how to read and interpret chest x-rays with expert guidance on common disease patterns, differential diagnoses, narrowing down the diagnoses, and further studies (from additional radiographic exams to CT or to biopsy). Each chapter follows a consistent format: Presenting Case, Questions, Discussion, Top 5 Diagnoses, Summary, and Answer Guide. Heavily illustrated with chest radiographs and additional CT, HRCT, and MR correlative images; plus bulleted summary boxes of comprehensive diagnoses lists and interpretation points. An ideal resource for mastering this lower-cost modality before considering more complicated and costly procedures. Illustrated case studies and quizzes feature new and improved questions that address the challenges seen in practice today. Significant updates on carcinoid tumors and pulmonary nodules, including pathologic descriptions, detection, management, and new terminology; new lung cancer screening guidelines and benefits of CT vs. x-ray for screening; and CT description of nodules, detection of pulmonary nodules with chest x-rays, anatomic and perception problems with x-rays in identifying nodules. New content on diffuse disease, including new pathologic terms and the latest impact of high resolution CT (HRCT). Updates on radiation dosing and emphasis on lower dosing, and an expanded emphasis on how to interpret x-rays and CT scans. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Stroke is the second leading cause of death and major cause of long-term disability, directly impacting the quality of life, worldwide. Strokes with more rare, and unknown causes unfortunately receive little to no attention due to the heterogeneity of disorders and a poor understanding of clinical features. There are considerable variations in the etiology of this rare sub-category of stroke; requiring heightened clinical awareness for recognition, evaluation and treatment. This book provides up-to-date guidance, through case reports concisely summarised by global leaders in the field describing the diagnosis and treatment of rare causes of stroke, from vasculitis, hypercoagulable states, hereditary and genetic factors, cardioembolism, vasculopathies, venous occlusive conditions to bone disorders. Offering practical advice and algorithms, this book aids the clinician in establishing an accurate diagnosis through detailed evaluation of such patients, leading to an early diagnosis improving risk assessment and family counselling.