This reference provides an authoritative overview of the role of ultrasonography and MR imaging technologies in the examination and assessment of the central nervous system of the fetus and neonate. Spanning advancements in fetal ultrasound, in-utero MR, the imaging of the neonatal brain, and the analysis of normal and abnormal brain development, this guide paints a vivid picture of the utilization and development of imaging technologies in modern prenatal and pediatric medicine.

With 2300 radiological images dispersed throughout the text, this source provides an expansive armamentarium of case studies and examples showcasing both common and uncommon liver pathologies. Serving as an unparalleled how-to source for the investigation of liver disease by MRI, this guide demonstrates key MRI techniques currently utilized in clinical practice, as well as explains the choice of acquisition sequences, specific parameters, and the use of contrast media for each application.

With up-to-date, easy-access coverage of every aspect of diagnostic radiology, Grainger and Allison's Diagnostic Radiology Essentials, 2nd Edition, is an ideal review and reference for radiologists in training and in practice. This comprehensive overview of fundamental information in the field prepares you for exams and answers the practical questions you encounter every day. In a single, convenient volume, this one-stop resource is derived from, and cross-referenced to, the renowned authoritative reference work Grainger & Allison's Diagnostic Radiology, 6th Edition. Concentrates on the subjects that general diagnostic radiologists need to know, covering all diagnostic imaging modalities and organized by organ and system. Uses a concise, highly templated, bulleted format that helps you find the answers you need quickly and easily. Features more than 2,000 high-quality images, including plain film, CT, MRI, and ultrasound. Presents images directly linked to relevant text on the facing page - no flipping back and forth to review the key radiological features of disease entities. Features a new section on interventional radiology that covers interventional vascular radiology techniques, cross sectional angiography, specific drainage techniques, tumor ablation principles, and intervention in hepatobiliary, genitourinary and gynecological conditions. Contains a new section on functional imaging which includes both MRI (diffusion weighted imaging and perfusion MRI) and PETCT. Includes diagnostic "pearls" that help you avoid pitfalls and errors in diagnosis. Includes a useful Appendix with many quick-reference items that are hard to remember but essential in day-to-day practice. New content includes intravascular contrast media, anticoagulation agents and sedation, the latest TNM 8th edition of staging cancers, and new section on PI-RADS and BI-RADS. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Multiple sclerosis (MS) is the most prevalent demyelinating disease of the central nervous system (CNS). It affects over 400,000 people in the USA alone and is a common disease world wide. This book will cover a new and emerging field in the development of strategies to treat MS. Until now, the only therapies available for MS treatment have been those directed against inflammation and the immune attack on the CNS. Other treatments are used for symptomatic relief. Remyelination of the CNS has been purely an experimental procedure to date, with many years of research on experimental remyelination in animal models of MS and other myelin disease. As more becomes known about the underlying pathophysiology of MS, it has become apparent that axon loss is a critical component of this primary demyelinating disease and that remyelination of axons at risk, i.e. demyelinated axons, may be the best neuroprotection available. Thus the idea of repairing myelin to both restore conduction to demyelinated fibers, as well as protecting them against future loss, is being seriously explored as a translational therapy. The purpose of this book will be to bring together the experts in the field to discuss what is required to move forward into the clinical application of tissue repair and neuroprotection. The book will begin with a discussion on myelin and the myelinating cell of the CNS and the current state-of-the- art on the cell and molecular biology of the cell, with particular reference toward myelin repair. The book will conclude with a chapter(s) on the clinical application of new myelin repair and axonal protection therapies and the methods by which these new therapies will be evaluated in clinical trials.

This comprehensive, case-based resource provides the state-of-the-art knowledge that can help readers improve access and optimize delivery of stroke thrombectomy. Improving access to stroke is of particular importance because patients often misinterpret their symptoms or cannot speak for themselves if they have aphasia. More importantly, access needs to be organized because stroke therapies are all extremely time-sensitive. Scalable, choreographed protocols are necessary for emergency medical systems to 'capture' stroke patients and automatically transport and triage to time-sensitive treatments. Many of the chapters in the first section on Fundamentals and Systems provide valuable insight in improving access to stroke care. Replete with illustrative case studies and emphasizing that treatment approaches to stroke should not be comprised of a one-size-fits-all approach, this illuminating title provides the complete thought, detail, insight and organization that will help readers meet the needs of stroke patients with large vessel occlusions. 12 Strokes: A Case-based Guide to Acute Ischemic Stroke Management examines the primary technical principles that underlie the current thrombectomy approaches. Instead of continuing the conceptual dichotomy of stent vs. aspiration, many of the chapters look at underlying principles and then discuss ways in which the currently available devices and approaches can best exploit them. The variety, creativity and detail in many of these chapters will help the reader develop a deeper understanding that might assist their ability to successfully take care of their next patient that 'doesn't follow the textbook.' In addition, the anatomic and pathophysiologic classification of the core Twelve Chapters will help readers organize their thinking and approach. This knowledge, particularly because it is organized based on common, challenging syndromes, will arm the reader to quickly recognize patterns and deftly adapt their management approaches to the needs of the patient. An invaluable contribution to the clinical literature, 12 Strokes: A Case-based Guide to Acute Ischemic Stroke Management will be of great interest to not only neurosurgeons and neurologists but other specialists, primary care providers, and trainees as well.

Intravascular Ultrasound (IVUS) is now recognized as an important adjunct to conventional angiography and is increasingly used to image atherosclerotic disease process in clinical research. The growing use of this technology has created a need for a resource that combines technical details with illustrative material. An Atlas and Manual of Coronary Intravascular Ultrasound Imaging provides, in a single volume, a practical reference manual that describes the application of the technique, and a superbly illustrated atlas that graphically demonstrates the capabilities of this rapidly evolving technology. Section One, the Manual, describes the rationale, technique, and interpretation of IVUS imaging for standard and evolving applications. It covers normal arterial anatomy, plaque morphology and imaging artifacts, together with measurement techniques and volumetric analysis, and the use of IVUS as a guide for interventional procedures such as atheroplasty, atherectomy, and stenting. In addition, emerging topics including plaque vulnerability and serial surveillance of plaque progression and regression are extensively described. Section Two, the Atlas, reviews these topics with reference to a series of carefully selected clinical cases, which allows the reader to further improve the capability to correctly interpret images obtained using this technique. Developed with the resources of one of the world's leading centers for IVUS imaging, the book systematically introduces coronary imaging with IVUS. A comprehensive reference, An Atlas and Manual of Coronary Intravascular Ultrasound Imaging presents an accessible introduction for the beginner and an invaluable reference for the more experienced practitioner.

Overuse injuries of the musculoskeletal system are common occurrences. Yet most existing volumes on cumulative trauma disorders deal with the subject from an ergonomic and occupational therapy standpoint, and do not provide the all-encompassing synopsis that physicians demand.

Overuse Injuries of the Musculoskeletal System, Second Edition answers the need by presenting a complete overview of the methods for diagnosing and treating the overuse injuries that affect the musculoskeletal system as a whole. Each chapter includes the definition, origins, clinical picture and diagnostics, and treatment for the given injury. The book goes beyond diagnosis and treatment by identifying etiological factors and discussing ways to prevent overuse injuries.

This new edition retains the successful systematic format that made the first edition a bestseller and an invaluable tool for orthopaedists, physical therapists, rheumatologists, radiologists and sports medicine practitioners. This version includes a new chapter on radiologic diagnosis, new chapter on overuse injuries in female athletes and supplements previously-existing chapters with new material.

This book provides an introduction to next generation smart screening technology for medical image analysis that combines artificial intelligence (AI) techniques with digital screening to develop innovative methods for detecting breast cancer. The authors begin with a discussion of breast cancer, its characteristics and symptoms, and the importance of early screening.They then provide insight on the role of artificial intelligence in global healthcare, screening methods for breast cancer using mammogram, ultrasound, and thermogram images, and the potential benefits of using AI-based systems for clinical screening to more accurately detect, diagnose, and treat breast cancer. Discusses various existing screening methods for breast cancer Presents deep information on artificial intelligence-based screening methods Discusses cancer treatment based on geographical differences and cultural characteristics

This book explains transparency in biology with emphasis on bending and absorption, which together are the essence of transparency. The reader is provided with an understanding of why the interior of the body can be made to appear transparent through the application of elementary physics. Based on the principle of transparency, emerging imaging techniques using near-infrared light to view the body transparently are explained with examples such as cancer detection and temperature imaging of deep tissues. This book is useful to many researchers, including biologists, physicists, chemists, materials scientists, and device engineers as well as developers-all who seek a deep understanding of transparency in bioimaging.

Covering a spectrum of important musculoskeletal pathologies that are commonly encountered in day-to-day practice, this book includes over 82 cases with all common complaints afflicting muscles, bones, joints, soft tissues, tendons and ligaments. Each case begins with a clinical history followed by ultrasound images with their description, diagnosis and relevant discussion pertaining to the case. Includes the high-resolution images. Emphasizes practical information that should be incorporated in the musculoskeletal ultrasound report so as to benefit the referring orthopedic surgeons or rheumatologists.

This book provides practical and pragmatic guidance in breast MRI for all professionals involved in breast imaging or the care of patients with breast diseases.

eBook available with sample pages: 0203215435

This book explores the physics, technology and applications of particle accelerators. It illustrates the interconnections between applications and basic physical principles, enabling readers to better understand current and upcoming technologies and see beyond the paradigmatic borders of the individual fields. The reader will discover why accelerators are no longer just toys for scientists, but have also become modern and efficient nuclear workhorses. The book starts with an introduction to the relevant technologies and radiation safety aspects of accelerating electrons and ions from several keV to roughly 250 MeV. It subsequently describes the physics behind the interactions of these particle beams with matter. Mathematical descriptions and state-of-the-art computer models of energy-loss and nuclear interactions between the particle beams and targets round out the physics coverage. On this basis, the book then presents the most important accelerator applications in science, medicine, and industry, explaining and comparing more than 20 major application fields, encompassing semiconductors, cancer treatment, and space exploration. Despite the disparate fields involved, this book demonstrates how the same essential technology and physics connects all of these applications.

This book fills the gap between the increasing demand for epilepsy surgical experience and limited training facilities in this area. It comprehensively describes surgical techniques, including tricks and pitfalls, based on the author's 30 years of experience, providing optimal and effective training for young neurosurgeons by avoiding learning by trial and error. Moreover, it also includes useful information for epileptologists and other professionals involved in the epilepsy surgical program to allow them to gain a better understanding of possibilities and limitations of epilepsy surgery.

This book provides an in-depth description and discussion of different multi-modal diagnostic techniques for cancer detection and treatment using exact optical methods, their comparison, and combination. Coverage includes detailed descriptions of modern state of design for novel methods of optical non-invasive cancer diagnostics; multi-modal methods for earlier cancer diagnostic enhancing the probability of effective cancer treatment; modern clinical trials with novel methods of clinical cancer diagnostics; medical and technical aspects of clinical cancer diagnostics, and long-term monitoring. Biomedical engineers, cancer researchers, and scientists will find the book to be an invaluable resource. Introduces optical imaging strategies; Focuses on multimodal optical diagnostics as a fundamental approach; Discusses novel methods of optical non-invasive cancer diagnostics.

This book critically assesses the current state of knowledge on new and important detection technologies, e.g. mass spectrometry, tandem mass spectrometry, biosensor detection and tissue imaging, in connection with toxic chemical and biological agents. In general, the main topics discussed concern the risks and consequences of chemical and biological agents for human health in general, with special emphasis on all biochemical and metabolic pathways including the reproductive system. The exposome, genetic risks and the environment, various health hazard agents, risk assessment, environmental assessment and preparedness, and analysis of sub-lethal effects at the molecular level are also discussed. In closing, the book provides comprehensive information on the diagnosis of exposure, and on health concerns related to toxic chemical and biological agents.

Written by a multidisciplinary group of contributors, including radiologists, emergency physicians, critical care specialists, anesthesiologists, and surgeons, Fundamentals of Emergency Ultrasound is a first-of-its-kind reference that clearly explains the many technical nuances and diagnostic skills necessary for optimal use of ultrasound in emergency settings. This concise, easy-to-read resource covers both non-invasive and invasive ultrasound-guided procedures for a wide range of adult and pediatric trauma and non-trauma conditions. A practical emphasis on differential diagnosis helps facilitate rapid diagnosis, triage, and disposition decisions in emergency situations where ultrasound can be used. Provides a depth of understanding and interpretation from a multidisciplinary group of chapter authors, with step-by-step details on anatomy, equipment considerations, positioning, technique, normal and abnormal findings, and common pitfalls. Covers invasive procedures and ultrasound-guided injections such as thoracentesis, paracentesis, nerve blocks, and central and peripheral venous access. Includes correlative CT, MR, and Doppler images to enhance ultrasound visualization, in addition to more than 500+ high-quality ultrasound images and 75+ line drawings. Offers up-to-date coverage on the e-FAST, trans-thoracic and trans-esophageal echocardiography, pulmonary, and cranial sonography, among other emergency modalities. Features more than 150 ultrasound video clips that show the many nuances of ultrasound use. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

This book provides an up-to-date overview of gastrointestinal malignancies, including prevention, early detection, intervention, and life-extending therapeutics. It also assesses various biomarkers used for diagnostics, prognostics and prediction of response to chemoresistance. Further, it discusses the latest trends in the use of small-molecule targeted therapies and immunotherapies as single agents or combination with other treatments. Since resistance to radiation and chemotherapy contribute to the high recurrence and poor survival rates, improving the outcome for GI malignancies is dependent on the introduction of new biomarkers and therapeutic agents. Lastly, the book systematically investigates novel theranostics approaches using nanotechnology for the detection, diagnosis, and personalized treatment of GI malignancies.

This book provides an essential overview of the broad range of functional brain imaging techniques, as well as neuroscientific methods suitable for various scientific tasks in fundamental and clinical neuroscience. It also shares information on novel methods in computational neuroscience, mathematical algorithms, image processing, and applications to neuroscience. The mammalian brain is a huge and complex network that consists of billions of neural and glial cells. Decoding how information is represented and processed by this neural network requires the ability to monitor the dynamics of large numbers of neurons at high temporal and spatial resolution over a large part of the brain. Functional brain optical imaging has seen more than thirty years of intensive development. Current light-using methods provide good sensitivity to functional changes through intrinsic contrast and are rapidly exploiting the growing availability of exogenous fluorescence probes. In addition, various types of functional brain optical imaging are now being used to reveal the brain's microanatomy and physiology.

Chiropractic Radiography and Quality Assurance Handbook is the first book devoted to erect and recumbent radiographic positioning and a practical approach to quality assurance and radiographic quality control testing. It provides a step-by-step approach to performing quality radiographic studies using radiographic images to demonstrate placement of anatomical markers and the safest location for patient identification information.
Some topics covered include:
o The importance of sound radiation safety practices and appropriate protection and collimation
o Spinal radiography including changes in positioning to reduce exposure to female patients
o Extremity radiography, covering common and specialty views to assist in diagnosis of sports injuries.
Designed for both the practitioner and the student, this book provides all of the tools necessary to produce quality radiographs in a quick reference, detailed, step-by-step approach to positioning. And adding information about darkroom and film storage, film processing quality control, film artifact identification and problem solving, makes this is an in-depth, authoritative guide.

This book takes account of recent changes in the Fellowship of the Royal College of Radiologists (FRCR) Part 2A examination. It includes basic radiological science questions as well as the original clinical imaging component, and in particular it discusses cross sectional imaging at an advanced level. Many of these questions are also very useful in preparation for the American Boards Exam in Radiology. Unlike other books in this field, this essential guide provides full explanatory answers and bibliography. Questions are divided into subject chapters corresponding to those in the current FRCR Part 2A syllabus, and structured in an identical fashion to the actual exam.

Aunt Minnie's Atlas and Imaging-Specific Diagnosis

This book covers virtually all aspects of image formation in medical imaging, including systems based on ionizing radiation (x-rays, gamma rays) and non-ionizing techniques (ultrasound, optical, thermal, magnetic resonance, and magnetic particle imaging) alike. In addition, it discusses the development and application of computer-aided detection and diagnosis (CAD) systems in medical imaging. Given its coverage, the book provides both a forum and valuable resource for researchers involved in image formation, experimental methods, image performance, segmentation, pattern recognition, feature extraction, classifier design, machine learning / deep learning, radiomics, CAD workstation design, human-computer interaction, databases, and performance evaluation.

The Radiologic Technology Clinical Manual is designed to guide students through all aspects of clinical training in the area of radiological sciences. This practical workbook contains student self-evaluation forms, course outlines, instructional objectives, and all the procedures and work assignments necessary for training students in the clinical side of radiologic technology. It can be used as a supplement to any radiologic sciences program. When used as part of an occupational training course in radiologic technology, the Radiologic Technology Clinical Manual will help students qualify for examination by the American Registry of Radiologic Technologists (ARRT). The book contains valuable record keeping materials for clinical experience hours, background on the profession as a whole, and evaluation forms for quarterly periods of clinical training. Time sheets, attendance forms, and clinical log forms are also included.

This third edition overviews the essential contemporary topics of neuroengineering, from basic principles to the state-of-the-art, and is written by leading scholars in the field. The book covers neural bioelectrical measurements and sensors, EEG signal processing, brain-computer interfaces, implantable and transcranial neuromodulation, peripheral neural interfacing, neuroimaging, neural modelling, neural circuits and system identification, retinal bioengineering and prosthetics, and neural tissue engineering. Each chapter is followed by homework questions intended for classroom use. This is an ideal textbook for students at the graduate and advanced undergraduate level as well as academics, biomedical engineers, neuroscientists, neurophysiologists, and industry professionals seeking to learn the latest developments in this emerging field.Advance Praise for Neural Engineering, 3rd Edition: "A comprehensive and timely contribution to the ever growing field of neural engineering. Bin He's edited volume provides chapters that cover both the fundamentals and state-of-the-art developments by the world's leading neural engineers." Dr. Paul Sajda, Department of Biomedical Engineering, Electrical Engineering and Radiology, Columbia University "Neural Engineering, edited by Prof. He, is an outstanding book for students entering into this fast evolving field as well as experienced researchers. Its didactic and comprehensive style, with each chapter authored by leading scientific authorities, provides the ultimate reference for the field." Dr. Dario Farina, Department of Bioengineering, Imperial College London, London, UK "Neural Engineering has come of age. Major advances have made possible prosthesis for the blind, mind control for quadraplegics and direct intervention to control seizures in epilepsy patients. Neural Engineering brings together reviews by leading researchers in this flourishing field. Dr. Terrence Sejnowski, Salk Institute for Biolgical Studies and UC San Diego

This handbook presents the most current information on the effects of ionizing radiation on mammalian cells, with emphasis on human tissues. The dose-effect relationship is emphasized in a quantitative manner. The book contains up-to-date data on the late effects of low levels of radiation on humans. It also provides some of the late consequences of radiation therapy detected among cancer survivors.