This handbook presents the most current information on the effects of ionizing radiation on mammalian cells, with emphasis on human tissues. The dose-effect relationship is emphasized in a quantitative manner. The book contains up-to-date data on the late effects of low levels of radiation on humans. It also provides some of the late consequences of radiation therapy detected among cancer survivors.

This book comprehensively reviews the recent advances in nanomaterial-based molecular imaging, diagnostics, and personalized therapy. It discusses the novel biocompatible fluorescent nanomaterials, their synthesis, and modern state of art characterization, as well as the various strategies for immobilization of biomacromolecules on the nanomaterial surface and approaches for increasing their stability. In addition, the book describes the synthesis of lectin nanoconjugates using different types of biocompatible raw materials and their systematic characterization. Lastly, it presents our current understanding of the biomolecular carona, which affects nanoparticle-based targeted drug delivery, and examines the conceptual approaches to improve the in-vivo efficacy of targeted drug delivery.

Increase your knowledge and improve your image interpretation skills using the proven and popular Case Review approach! Drs. Wael E. Saad, Minhaj S. Khaja, and Suresh Vedantham have updated this new edition to include nearly 200 clinically relevant cases with associated images, multiple-choice questions, answers, and rationales - all organized by level of difficulty and designed to reinforce your understanding of the essential principles needed to interpret a wide range of vascular and interventional images. Study effectively with content that addresses contemporary medical practice emphasizing physics, clinical evaluation, and treatment following The Joint Commission and the Accreditation Council for Graduate Medical Education. View cases that reflect contemporary practice, thanks to new, multi-modality imaging, including color images and 3D reconstructions. Stay up to date with recent innovations in vascular and interventional radiology with a more diverse case selection, updated procedural techniques and inventory, and new and updated references from reputable sources. Get fresh perspectives from nearly 200 updated or new cases reflecting the most recent changes in vascular and interventional radiology, including portal hypertension, aortic disease, interventional oncology, peripheral arterial disease, and complex venous disease.

Key Features * Sets the standard for training and competency of this emerging, yet scientifically approved non-invasive technique of ultrasound with all the essential information on how to perform ultrasound and interpret the images obtained. * Features clear and didactic images demonstrating echo findings in various situations along with videos of diaphragmatic ultrasound offering a unique "window" on mechanically ventilated patients, allowing to take important clinical decisions on ventilatory modes and assistance by pulmonologists, critical care specialists, thoracic surgeons, emergency medicine specialists as well as trainees. * Includes a chapter on pediatric ultrasound along with ultrasound of other respiratory muscles (i.e., intercostal and abdominal) which is emerging as a useful complementary tool.

Editor Savvas Nicolaou, MD and authors provide a comprehensive review of Emergency and Trauma Radiology. Articles will include: Improving outcomes in the polytrauma patient: a review of the role of whole body CT; Advanced imaging in the emergency department: dual energy CT in the acute setting; Imaging of traumatic brain injury: basic concepts and future direction; Imaging patterns and management algorithms in acute stroke: an update for the emergency radiologist; Imaging of non-traumatic neuroradiology emergencies; Pearls and pitfalls in C-spine trauma with new concepts; Face and neck infections: What the emergency radiologist needs to know; Negative CT for acute pulmonary embolism: important differentials in acute dyspnea; Imaging of penetrating thoracic injury; Imaging of easily missed fractures in the upper extremity; Imaging of easily missed fractures in the lower extremity; Imaging of genitourinary trauma; Imaging of ischemia, obstruction and infection in the abdomen; Imaging of pancreatic and duodenal trauma; and more!

Computational Biomechanics for Medicine: Solid and fluid mechanics for the benefit of patients contributions and papers from the MICCAI Computational Biomechanics for Medicine Workshop help in conjunction with Medical Image Computing and Computer Assisted Intervention conference (MICCAI 2019) in Shenzhen, China. The content is dedicated to research in the field of methods and applications of computational biomechanics to medical image analysis, image-guided surgery, surgical simulation, surgical intervention planning, disease prognosis and diagnostics, analysis of injury mechanisms, implant and prostheses design, as well as artificial organ design and medical robotics. These proceedings appeal to researchers, students and professionals in the field.

This book provides a broad overview of pancreatic neuroendocrine neoplasms, focusing on the most important developments in the technologies used to diagnose, classify and treat them. After a historical and epidemiological overview, the opening chapters examine the various diagnostic approaches (radiology, nuclear medicine, endocrinology, cytology and immunohistochemistry) and discuss the WHO classification. The functioning and nonfunctioning tumor types are then fully discussed, covering epidemiology, diagnosis, morphology and prognosis of each entity. Careful consideration is given to the molecular features that have contributed in understanding the pathogenesis of such neoplasms and may have potential implications for the diagnostic and therapeutic pathways. The final chapters consider the surgical and medical approaches to therapy, providing a practical and analytical overview of the available options. The book is written by a multidisciplinary team of worldwide-recognized experts and is addressed to radiologists, nuclear medicine physicians, endocrinologists, pathologists, surgeons and oncologists.

Teleradiologische Befundung wird immer wichtiger fur Kliniken, die sich nachts und Feiertags keinen Radiologen leisten koennen oder wollen. Mit der immer populareren Telemedizin ist auch die Teleradiologie seit Jahren immer mehr gewachsen. Ziel des Buches ist es, umfassend uber das teleradiologische Arbeiten, die Moeglichkeiten, Arbeitsablaufe, Infrastruktur und Anwendungsbereiche zu informieren. Dabei wird sowohl die Anwenderseite (der radiologische Arzt als Befunder) als auch die Auftraggeber-Seite (die Kliniken) beleuchtet, die hier eng verzahnt interagieren mussen. Inhalte: Das Buch informiert den Leser umfassend uber die folgenden Aspekten der Teleradiologie AErztliche Aspekte Sicht des Krankenhaus-Managements, gesetzliche Vorgaben (Strahlenschutzgesetz und -verordnung), DIN-Normen, Arbeitsablaufe, Genehmigungsprozess, Qualitatsaspekte, Integration in die IT-Landschaft der Beteiligten, Kommunikationsstandards in der Medizin/Radiologie, Beispiele realisierter Teleradiologie-Netzwerke, Datenschutz und Rechtsfragen .

This book presents non-linear image enhancement approaches to mammograms as a robust computer-aided analysis solution for the early detection of breast cancer, and provides a compendium of non-linear mammogram enhancement approaches: from the fundamentals to research challenges, practical implementations, validation, and advances in applications. The book includes a comprehensive discussion on breast cancer, mammography, breast anomalies, and computer-aided analysis of mammograms. It also addresses fundamental concepts of mammogram enhancement and associated challenges, and features a detailed review of various state-of-the-art approaches to the enhancement of mammographic images and emerging research gaps. Given its scope, the book offers a valuable asset for radiologists and medical experts (oncologists), as mammogram visualization can enhance the precision of their diagnostic analyses; and for researchers and engineers, as the analysis of non-linear filters is one of the most challenging research domains in image processing.

Musculoskeletal Imaging Volume 2 provides a comprehensive review of the subject matter commonly encountered by practicing radiologists and radiology residents in training. This volume includes succinct overviews of metabolic, infectious, and congenital diseases; internal derangement of joints; and arthography, and ultrasound. Part of the Rotations in Radiology series, this book offers a guided approach to imaging diagnosis with examples of all imaging modalities complimented by the basics of interpretation and technique and the nuances necessary to arrive at the best diagnosis. Each pathology is covered with a targeted discussion that reviews the definition, clinical features, anatomy and physiology, imaging techniques, differential diagnosis, clinical issues, key points, and further reading. This organization is ideal for trainees' use during specific rotations, for exam review, or as a quick refresher for the established musculoskeletal imager. It is a must-read for residents and practicing radiologists seeking a foundation for the essential knowledge base in musculoskeletal imaging. Musculoskeletal Imaging Volume 1 reviews trauma, arthritis, and tumor and tumor-like conditions.

Explore important research approaches and concepts within diagnostic radiography Provide contemporary evidence-based practice regarding mixed method approaches Provide a clear and 'how to guide' for understanding key research principles in a wide range of radiographic settings Evaluate the impact of research on patients and the radiographer-patient relationship

This book covers emerging trends in signal processing research and biomedical engineering, exploring the ways in which signal processing plays a vital role in applications ranging from medical electronics to data mining of electronic medical records. Topics covered include statistical modeling of electroencephalograph data for predicting or detecting seizure, stroke, or Parkinson's; machine learning methods and their application to biomedical problems, which is often poorly understood, even within the scientific community; signal analysis; medical imaging; and machine learning, data mining, and classification. The book features tutorials and examples of successful applications that will appeal to a wide range of professionals and researchers interested in applications of signal processing, medicine, and biology.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. 200 interactive brain imaging cases deliver the best board review possible! Part of McGraw-Hill's Radiology Case Review Series, this unique resource challenges you to look at a group of images, determine the diagnosis, answer related questions, and gauge your knowledge by reviewing the answer. It all adds up to the best review of brain imaging imaging available-one that's ideal for certification or recertification, or as an incomparable clinical refresher. Distinguished by a cohesive 2-page design, each volume in this series is filled with cases, annotated images, questions & answers, pearls, and relevant literature references that will efficiently prepare you for virtually any exam topic. Radiology and neurology residents and fellows, medical students, radiologists, and physicians who want to increase their knowledge of brain imaging will find this book to be an invaluable study partner.

Handbook for Clinical Trials of Imaging and Image-Guided Interventions is the first single-source, multi-disciplinary reference, based on the didactic sessions presented at the annual Clinical Trials Methodology Workshop for radiologists, radiation oncologists and imaging scientists (sponsored by the Radiological Society of North America (RSNA)). It focuses on educating radiologists, radiation oncologists and those involved in imaging research with how to design and conduct clinical trials to evaluate imaging technology and imaging biomarkers. The internationally renowned contributors take a broad approach, starting with principles of technology assessment, and then move into specific topics covering the clinical trials of therapy and clinical research in imaging guided interventions including radiotherapy. They discuss the use of imaging as a predictor of therapeutic response, screening trial design, and the practicalities of how to run an efficient clinical trial and good working practices. Later chapters provide a comprehensive array of quantitative methods including: an introduction to statistical considerations in study design, biostatistical analysis methods and their role in clinical imaging research, methods for quantitative imaging biomarker studies, and an introduction to cost effectiveness analysis. Handbook for Clinical Trials of Imaging and Image-Guided Interventions will educate and prepare radiologists at all levels and in all capacities in planning and conducting clinical imaging trials.

This book illustrates the significance of biomedical engineering in modern healthcare systems. Biomedical engineering plays an important role in a range of areas, from diagnosis and analysis to treatment and recovery and has entered the public consciousness through the proliferation of implantable medical devices, such as pacemakers and artificial hips, as well as the more futuristic technologies such as stem cell engineering and 3-D printing of biological organs. Starting with an introduction to biomedical engineering, the book then discusses various tools and techniques for medical diagnostics and treatment and recent advances. It also provides comprehensive and integrated information on rehabilitation engineering, including the design of artificial body parts, and the underlying principles, and standards. It also presents a conceptual framework to clarify the relationship between ethical policies in medical practice and philosophical moral reasoning. Lastly, the book highlights a number of challenges associated with modern healthcare technologies.

Following the sucess of the previous editions of this established text, the sixth edition of "Chesneys' Radiographic Imaging "reflects the advances in radiography education and practice, and the changing role of the radiographer. With the needs of the student in mind, the authors have identified the growing need to reference source material wherever possible. Coverage of radiographic imaging processed has been revised and updated throughout. Digital technology has been expanded and new sections on digital picture archiving and communication systems and computed radiography have been introduced. Descriptions of dry silver imaging and receiver operating characteristics have been included. The importance of health and safety in processing areas is also covered.

"Chesneys' Radiographic Imaging" provides a sound knowledge base for students. It will also be of interest to radiographers working in an increasingly demanding workplace with new technology of ever increasing complexity.

This book gathers the proceedings of the 17th International Conference on Electrical Bioimpedance (ICEBI 2019), held on June 9-14, in Joinville, Santa Catarina, Brazil. The chapters cover the latest knowledge and developments concerning: sensors and instrumentation to measure bioimpendance, bioimpedance imaging techniques, theory and modeling and bioimpendance, as well as cutting-edge clinical applications of bioimpendance. All in all, this book provides graduate students and researchers with an extensive and timely snapshot of current research and challenges in the field of electrical bioimpendance, and a source of inspiration for future research and cross-disciplinary collaborations.

Stroke is the second leading cause of death and major cause of long-term disability, directly impacting the quality of life, worldwide. Strokes with more rare, and unknown causes unfortunately receive little to no attention due to the heterogeneity of disorders and a poor understanding of clinical features. There are considerable variations in the etiology of this rare sub-category of stroke; requiring heightened clinical awareness for recognition, evaluation and treatment. This book provides up-to-date guidance, through case reports concisely summarised by global leaders in the field describing the diagnosis and treatment of rare causes of stroke, from vasculitis, hypercoagulable states, hereditary and genetic factors, cardioembolism, vasculopathies, venous occlusive conditions to bone disorders. Offering practical advice and algorithms, this book aids the clinician in establishing an accurate diagnosis through detailed evaluation of such patients, leading to an early diagnosis improving risk assessment and family counselling.

Biostatistics for Oncologists is the first practical guide providing the essential biostatistical concepts, oncology-specific examples, and applicable problem sets for medical oncologists, radiation oncologists, and surgical oncologists. The book also serves as a review for medical oncology and radiation oncology residents or fellows preparing for in-service and board exams. All examples are relevant to oncology and demonstrate how to apply core conceptual knowledge and applicable methods related to hypothesis testing, correlation and regression, categorical data analysis and survival analysis to the field of oncology. The book also provides guidance on the fundamentals of study design and analysis. Written for oncologists by oncologists, this practical text demystifies challenging statistical concepts and provides concise direction on how to interpret, analyze, and critique data in oncology publications, as well as how to apply statistical knowledge to understanding, designing, and analyzing clinical trials. With practical problem sets and twenty-five multiple choice practice questions with answers, the book is an indispensable review for anyone preparing for in-service exams, boards, MOC, or looking to hone a lifelong skill. Key Features: Practically explains biostatistics concepts important for passing the hematology, medical oncology, and radiation oncology boards and MOC exams. Provides guidance on how to read, understand, and critique data in oncology publications. Gives relevant examples that are important for analyzing data in oncology, including the design and analysis of clinical trials. Tests your comprehension of key biostatistical concepts with problem sets at the end of each section and a final section devoted to board-style multiple choice questions and answers Includes digital access to the eBook

In 2012, the American Board of Medical Specialties (ABMS) approved Interventional Radiology (IR) as its own specialty. Born out of the field of Diagnostic Radiology, IR requires a more clinical focus on initial consultation and post-procedural management, rather than its previous role of performing image-guided procedures. Interventional Radiology: Fundamentals of Clinical Practice is written with this new focus in mind to help readers incorporate their procedural knowledge into a holistic approach of patient management. Chapters explore topics across a broad spectrum of IR, with a focus on etiology and pathophysiology of disease, followed by discussions on intra-procedural and post-procedural management. Numerous tables and boxes, and over 420 total figures complement chapter content. This comprehensive text is a must-have for IR residents and all practicing interventional radiologists.

This book offers the first comprehensive overview of artificial intelligence (AI) technologies in decision support systems for diagnosis based on medical images, presenting cutting-edge insights from thirteen leading research groups around the world. Medical imaging offers essential information on patients' medical condition, and clues to causes of their symptoms and diseases. Modern imaging modalities, however, also produce a large number of images that physicians have to accurately interpret. This can lead to an "information overload" for physicians, and can complicate their decision-making. As such, intelligent decision support systems have become a vital element in medical-image-based diagnosis and treatment. Presenting extensive information on this growing field of AI, the book offers a valuable reference guide for professors, students, researchers and professionals who want to learn about the most recent developments and advances in the field.

This book is based on the best contributions to the advancement of bioimpedance knowledge and use from the Latin American Congress series, CLABIO. Basic bioimpedance facts as well as promising and original contributions to bioimpedance theory and applications are presented, giving the reader stimulating material for reflection, decision making, and further experiments. Contributions come from a diverse international pool of experts and address topics on electrode and skin impedance modelling, tomography, spectroscopy, instrumentation, and clinical applications.

This book provides detailed practical guidelines on how to develop an efficient pathological brain detection system, reflecting the latest advances in the computer-aided diagnosis of structural magnetic resonance brain images. Matlab codes are provided for most of the functions described. In addition, the book equips readers to easily develop the pathological brain detection system further on their own and apply the technologies to other research fields, such as Alzheimer's detection, multiple sclerosis detection, etc.

In compiling this textbook on the exciting novel imaging modality of PET/MRI, the editors have brought together a truly international group of experts in the field. The book is divided into two parts. The first part covers methodology and equipment and includes chapters on basic molecular medicine, contrast agents, MR attenuation and validation, and quantitative MRI and PET motion correction. The second part of the book focuses on clinical applications in oncology, cardiology, and neurology. Imaging of major neoplasms is covered in a series of individual chapters. Further chapters address functional and metabolic cardiovascular examinations and major central nervous system applications such as brain tumors and dementias. This book will be of interest to all radiologists and nuclear medicine physicians who wish to learn more about the latest developments in this important emerging imaging modality and its applications.

This book reviews and discusses the development of self-assembled nanomaterials applied in biomedical fields. Based on self-assembled nanomaterial constructions, it highlights the mechanisms of the stimuli-response-induced assembly/disassembly and transformation. Moreover, it examines healthcare-related diseases, the applications of nanomaterials and therapy/detection strategies, providing readers with both a deeper understanding of the subject and inspirations for future research. The book is primarily intended for researchers and graduate students in the fields of material sciences and chemistry who wish to learn about the principles, methods, mechanisms and biomedical applications of self-assembled nanomaterials.