Physicians caring for children with rheumatic disease need a varied and highly developed set of clinical skills, including general pediatrics, immunology, musculoskeletal medicine and the management of chronic diseases.
With these requirements in mind, the authors of this concise handbook emphasize the most frequently recognized symptom complexes in children. Their initial focus is on musculokeletal diseases that may have multi-organ involvement. They then discuss systemic lupus erythematosis, vasculitis, scleroderma and other auto-inflammatory diseases. Concise text is supported by a wealth of photos and tables.
The book is of use to all young doctors/residents in pediatrics, rheumatology and general medicine, to primary care physicians, and all those in related health disciplines caring for children with rheumatic disease.

Now in a revised and expanded second edition, this practical text utilizes the most current evidence and knowledge of articular cartilage as the basis for clinical interventions for cartilage repair and restoration, combining an overview of clinical research and methodologies with clinical cases to help guide the orthopedic treatment and care of patients presenting with cartilage issues. Carefully updated chapters discuss the state-of-the-art in cartilage anatomy, defects and imaging, current tibiofemoral and patellofemoral surgical options, debridement and marrow stimulation, osteochondral autografts and allografts, osteotomies, cell therapy, and meniscal transplantation. New chapters explore new surgical treatment strategies and revision for failed cartilage repair, case vignettes presenting real-life treatment decisions and outcomes, and rehabilitation protocols following cartilage repair. Written and edited by experts in the field and bringing the most recent literature and research to bear, Cartilage Restoration remains a valuable resource on joint preservation for orthopedic surgeons, residents, and fellows, sports medicine specialists and rheumatologists.

This volume provides a summary of the standard laboratory protocols and methodology commonly used in basic and translational studies in the field of rheumatoid arthritis (RA) treatment. Chapters detail including basic RA models, evaluation of disease activity and immunological status, systemic drug delivery, and new research tools. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Rheumatoid Arthritis: Methods and Protocols aims to be a basic manual for clinical researchers who are just getting started in the field of intervention study.

While an emphasis on the new is vital to any science, the relevance or importance of new discoveries cannot truly be appreciated without a strong sense of the framework of a discipline, and of the ideas that helped to shape it. With this in mind, the editors of this book have attempted to create a canon of texts that formed the basis of rheumatology. Experts on the diagnosis and management of the various rheumatological conditions have chosen what they consider to be the key papers in their respective domains. Every paper is carefully described and evaluated by its strengths, its weaknesses, and its contribution to the field. Papers have been chosen that define new diseases or treatments, that have changed our whole way of thinking, or that have simply stood the test of time. The editors hope that the papers profiled in this volume will stimulate debate, encourage readers to seek out the original texts, and inspire the writers of the classics of the 21st century.

Key Features * Features concise yet thorough description of the landmark studies and scientific breakthroughs coupled with easy-to-follow organizational structure of chapters that are accessible to readers at different levels of training. * Brings together world-leading experts to provide a fresh perspective to trainees such as residents and fellows-in-training, as well as more senior clinicians and researchers across the field of rheumatology and in specialties such as cardiology, dermatology, pulmonology, nephrology, and neurology, all of whom care for patients with rheumatologic conditions. * Allows the author to imagine and speculate about the evolution of this field in the coming decades. Examples of such speculative possibilities include use of synovial biopsy to predict response to treatment in rheumatoid arthritis, replacement of renal biopsy with urinary proteomics in diagnosing and classifying lupus nephritis, use of new therapeutics to obviate the need for steroids in the treatment of ANCA-associated vasculitis, use of machine learning to evaluate subtle changes in imaging in management of inflammatory arthritis, etc.

The Osteoarthritis chart features a large skeletal image displaying with generally affected joints being labeled. Sagittal views of healthy and OA affected joints and cartilage are shown, along with a 2-part diagram of nutrient exchange. Heavy gauge 3ml lamination with sealed edges and two metal eyelets for hanging makes chart highly durable. Write-on/wipe-off with dry erase marker (not included).

Ankylosing Spondylitis is an inflammatory arthritis that affects the spine and sacroiliac joints as well as other parts of the body, and that can eventually lead, in some patients, to complete fusion of the vertebrae and total rigidity. AS is not a rare health problem, but is in fact found in almost one percent of the US population, typically strikes young people and young families, and in its various forms is probably more common than rheumatoid arthritis. In this invaluable guide, Dr. Michael H. Weisman, one of America's leading authorities on AS, provides a down-to-earth, crystal-clear guide that is ideal for patients and their family. Dr. Weisman explains what AS is, discusses the genetic background to the disease (including the genes that researchers think may predispose some people to AS), explains how to diagnose the disease early and possibly prevent the later development of debilitating rigidity, the use of MRI for early detection, and much more. The book outlines which medications (such as TNF inhibitors) seem the most promising right now, the various drug side effects, the value of physical therapy, other treatment approaches, and whether surgery can be used to manage the complications of the disease. AS can lead to severe disability, but even those who have a milder form will experience painful "flares" alternating with periods of remission. Since it is a progressive disease in many patients, it is very important to reach patients as early as possible. This book will arm patients with the vital information they need to combat the disease. Laurie M. Savage, the Executive Director of the Spondylitis Association of America (SSA), the main patient support group world-wide, has written a foreword to the book. In addition, SSA will endorse the book and their logo will appear on the cover.

Leading clinical experts survey the latest information available on the key rheumatic and allergic issues that physicians face in treating the HIV-infected patient. The physicians focus on the rheumatologic and dermatologic manifestations of HIV-1 infection, which include arthritis, myopathies, vasculitis, sicca syndrome, other autoimmune phenomena, and psoriasis. They also examine the question of allergic reactions in HIV patients, including drug hypersensitivity, with special attention given to adverse reactions to trimethoprim-sulfamethoxazole, the most frequently prescribed anti-infective. Practical advice for the diagnosis and treatment of these problems is given in full.

"Rheumatology Practice in Occupational Therapy" is a valuable new handbook focusing on the core area of rheumatology. It provides practical guidance to help occupational therapists treat and manage rheumatic disease in both clinical and community settings and emphasizes a contemporary 'client-centred' approach as a fundamental requirement of effective and rewarding OT practice. Drawing upon personal, clinical and theoretical perspectives, it equips the reader with an understanding not only of relevant practical skills but of the clinical reasoning required to modify and apply these skills to the needs of individual people.

Focusing on the key essentials you need to know, Axial Spondyloarthritis provides a quick, expert overview of axSpA from a clinical perspective. This concise resource by Drs. Philip Mease and Muhammad Khan presents practical recommendations and guidelines for the diagnosis, management, and treatment of spondyloarthritis impacting the axial skeleton alongside an overview of epidemiology, special populations, and patient education. Discusses key information on genetic factors and disease biomarkers. Presents an overview of clinical features, classification criteria, and imaging to aid in diagnosis. Covers management and treatment guidelines, including non-pharmacologic management and the use of biologics. Consolidates essential information on this timely topic into a single, convenient resource.

This book is a practical and up-to-date review that discusses the impact of traditional cardiovascular risk factors in patients with rheumatoid arthritis, the effect of rheumatoid arthritis disease activity and severity on cardiovascular comorbidity, and the influence of rheumatoid arthritis drug therapy on cardiovascular risk. This title also explores cardiovascular disease as a manifestation of rheumatoid arthritis and highlights the available methods for screening and diagnosing these conditions. Current and emerging therapies to aid clinicians in the daily management of their patients are also featured in this title. Busy healthcare professionals who are looking for a collaborative approach to these conditions will benefit from this comprehensive overview.

Osteoporosis is the most common bone disease and is associated with pathological fractures that can lead to significant morbidity. It represents an economic burden to the health care system, directly linked to an ageing population. Guidelines on osteoporosis prevention have been published but these do not provide the required specialised knowledge for the treating physician. This book 'fills the gap' and focuses on the principles of surgical and medical treatment of osteoporosis. It aims to improve education and provide answers based on current evidence, helping doctors follow best practice, improve patient care and outcomes, and minimise the complications of medical and surgical management.

This comprehensive book grants readers exclusive insight into current advancements in the field of osteoarthritis (OA). Contributions from leading scientists and clinicians provide a detailed introduction into current understanding of the pathogenesis of OA, different joint structures affected by this debilitating disease (hip, knee, elbow, shoulder, foot, ankle, hand, wrist, and spine), current knowledge and practice in imaging, joint conservative strategies, OA biomarkers as well as currently available treatments, their safety profile and future therapeutic targets. This book further discusses the potential of regenerative therapies and recent advances in OA Personalized Medicine, and how collection of OA patient’s phenotypic, genetic and proteomic data is able to direct treatment strategies through Bio-Informatics.

This comprehensive volume provides current state of the art of the use of corticosteroids in the pediatric patient. It consists of 14 chapters written by leading authors from different countries. The first chapters cover historical notes, general concepts on treatment with corticosteroids with regard to indications and side effects, and basic pharmacologic properties of these compounds. The rest of the book is devoted to the specific use of steroids in the different pediatric subspecialties. Despite advances with newer effective immunosuppressive and anti-inflammatory drugs, corticosteroids still remain the mainstay of therapy for many disorders. Leading authors in their field have summarized these concepts to provide an authoritative, comprehensive guide to help clinicians safely and effectively use corticosteroids in their pediatric patients.

Behcet's syndrome can reasonably be considered a unique entity among diseases of the immune system for several reasons: It has specific features and, uniquely among the immune system pathologies, represents a link between autoimmune diseases, systemic vasculitis, and autoinflammatory diseases. In addition, it is of interest to a variety of specialists, including immunologists, rheumatologists, dermatologists, and ophthalmologists, and requires a complex multidisciplinary approach. Many aspects need to be considered in a syndrome that presents a wide spectrum of symptoms and for which the therapeutic armamentarium is expanding significantly, with the development of new treatments, not least the so-called biologics. This book offers comprehensive coverage of the disease by some of the world's leading experts in Behcet's syndrome from all the relevant specialties. Epidemiology, genetics, pathogenesis, organ system involvement, differential diagnosis, novel treatments, surgical management, and prognosis are just some of the topics addressed. Behcet's Syndrome: From Pathogenesis to Treatment will be an invaluable reference for a range of practitioners, researchers, and undergraduates or postgraduates interested in immuno-rheumatology, dermatology, and rare diseases.