The Oxford Dictionary of Sports Science and Medicine provides comprehensive and authoritative definitions of nearly 8000 sports science and sports medicine terms. All major areas are covered, including exercise psychology, sports nutrition, biomechanics, anatomy, sports sociology, training principles and techniques and sports injury and rehabilitation The dictionary will be an invaluable aid to students, coaches, athletes and anyone wanting instant access to the scientific principles, anatomical structures, and physiological, sociological and psychological processes that affect sporting performance. It will also be of interest to the general reader interested in sports science and medicine terminology.

This book provides a comprehensive and up-to-date review of the basic and clinical aspects of infections and infectious processes that trigger or aggravate a variety of autoimmune and inflammatory musculoskeletal disorders. It delivers a timely update on the interactions between infection and rheumatic diseases in order to provide clinicians with the tools they need for proper diagnosis and treatment. The book is divided into five main sections. The first examines the basic aspects of bacterial infections with a discussion of molecular biology, the microbiome, various types of bacteria that cause infection, and recent advances in biologic therapy. The next section focuses on different forms of viral arthritis including hepatitis arthritis, arthritis associated with alpha viruses, and parvovirus-related arthritis. Subsequent chapters then discuss arthritis caused by mycobacteria, fungi, spirochete, and other miscellaneous arthritides. Following this are various analyzations on reactive arthritis and infection-related rheumatic diseases such as Whipple's Disease, SAPHO Syndrome, rheumatic fever, and HIV-associated rheumatic manifestations. Finally, the book closes with three chapters on external impacts on infectious diseases such as climate change, vaccinations and systemic lupus erythematosus. Infections and the Rheumatic Diseases is an essential resource for physicians and related professionals, residents, fellows, graduate students, and nurses in rheumatology, clinical immunology, and internal medicine.

Since the publication of the first edition in 1959, Apley's System of Orthopaedics and Fractures has been an essential textbook for those seeking to understand the structure and function of the musculoskeletal system, its diseases and its response to trauma. The book's success was initiated by the late Alan Apley's skills as a teacher, and the care and forethought that he brought to the presentation of the content.
The current authors have developed and extended this foundation to produce a thoroughly modern textbook of orthopaedic surgery, bringing complementary expertise while retaining the book's characteristic philosophy and approach. They are joined by a selection of expert contributors from around the world, who add material on a wide variety of subjects including radiology, open fractures, neuromuscular disorders, and inflammatory arthropathies.
This 9th edition echoes its predecessors in following Apley's approach to the orthopaedic patient. As before, the work is divided ino three section: General Orthopaedics, Regional Orthopaedics, and Fractures and Joint Injuries. The material has been fully updated and revised, including the replacement of the majority of the photographs, giving this edition a modern and relevant feel. The illustrations are all provided in a downloadable form on the book's accompanying website.
Apley's System's wide readership of practicing orthopaedic surgeons, postgraduate trainees and residents in orthopaedics and general surgery, A&E specialists and physiotherapists is evidence of the author's ability to instruct and inspire. The book is a trully fitting introduction to modern-day orthopaedics.

This volume focuses on IgG4-related disease (IgG4-RD), a novel clinical entity involving multiple organs and of unknown origin, associated with the abundant infiltration of IgG4-positive cells. It consists of nine chapters written by prominent experts in the field and discusses the disease concept, diagnosis and treatment, as well as recent findings on its pathogenesis and pathophysiology. As such, it offers an invaluable source of information for researchers and clinicians alike.

This new edition is a comprehensive and updated resource on antiphospholipid syndrome (APS), which is an autoimmune disorder. In APS, the body recognizes certain normal components of blood and/or cell membranes as foreign substances and produces antibodies (antiphospholipid antibodies) against them. APS is associated with recurrent clotting events (thrombosis) including premature stroke, repeated miscarriages, phlebitis, venous thrombosis, and pulmonary thromboembolism. It is also associated with low platelet or blood elements that prevent bleeding. Recently, however, even more disease states have been linked with APS, including premature heart attack, various cardiac valvular abnormalities, skin lesions, kidney disease, abnormal involuntary movement/chorea, diseases that mimic multiple sclerosis, and vascular diseases of the eye that can lead to visual loss and blindness. The International Congress on Antiphospholipid Antibodies, held every 3 years, is the venue where representatives from different disciplines gather to discuss the recent advances in APS. The conference intends to cover basic aspects of APS, such as pathogenesis, origins, genetics, intracellular and molecular events, the role of infections, as well as traditional and non-traditional clinical manifestations associated with antiphospholipid antibodies. The 15th Congress took place in September 2016. A novel aspect of the Congress was that multiple teams, chaired by Scientific Planning Committee members, used evidence-based literature reviews and expert discussions to answer specific pre-defined APS-related questions. These teams included points of view from experts in rheumatology, hematology, cardiovascular medicine, obstetrics, neurology, and immunology. The Scientific Planning Committee members also chaired the congress sessions and supervised completion of the reports that are the bases of the chapters of this book. In addition, there are two chapters included specifically written for APS patients. Much like the previous volume, dedicated to the 13th International Congress on Antiphospholipid Antibodies (April 2010), this up-to-date and comprehensive work gathers invaluable insights from a multidisciplinary team of world-renowned experts and represents the authoritative resource on causes, symptoms, diagnosis, and treatment of APS.

Comprised of the authoritative work of international experts, this fully-updated second edition of Scleroderma builds upon the well-regarded approach in the first edition to provide integrated, concise, and up-to-date synthesis of current concepts of pathogenesis and modern approaches to management of systemic sclerosis (scleroderma). With a multidisciplinary approach to comprehensive care, this book is easily accessible for health care professionals in many fields. The new edition includes extensive updated material based on major developments in the field, with new chapters on personalized medicine, cancer complications, global perspectives on scleroderma, and more. It presents a succinct and thoughtful synthesis of current pathomechanistic concepts, providing a valuable reference tool for basic and translational investigators working in the field. Scleroderma: From Pathogenesis to Comprehensive Management serves as an essential, all-inclusive resource for rheumatologists, pulmonologists, cardiologists, gastroenterologists, nephrologists and all those involved in the care of scleroderma patients.

Utilizing a multidisciplinary approach and drawing on the experience of experts in their respective fields, this unique book presents and discusses an array of topics relevant to the ever-growing population of pediatric, adolescent and young adult female athletes. Each topic is clearly defined and includes epidemiology, diagnosis, treatment and future directions. Opening chapters discuss growth and development, sports nutrition, resistance training, and psychological considerations for the young female athlete, with a chapter focusing on the female athlete triad. Later chapters present injuries and management strategies common to the young female athlete, such as overuse injuries, spondylolysis, hip and ACL injuries, concussion, and cardiovascular complications. The concluding chapter considers the benefits of physical activity for chronic disease prevention later in life. The Young Female Athlete provides useful, up-to-date information for any practitioner treating this active population, encouraging sports participation with fitness, injury prevention, personal growth, and long-term health.

This volume reviews the current state of research on the IgM antibody and its multiple receptors and binding proteins. Interactions of the IgM ligands with these molecules are important for protection against infections as a first line of defense, as well as for regulation of immune responses to pathogens and self-antigens. The book includes up-to-date information on: (i) the phylogeny of three IgM-binding receptors [polymeric Ig receptor (pIgR), Fc receptor for both IgA and IgM (Fc /R), and Fc receptor for IgM only (FcR)]; (ii) the lymphocyte-restricted distribution and unique ligand-binding activity of FcR; (iii) the definition and potential function of Fc receptor-like molecule A (FCRLA) as a resident endoplasmic reticulum protein that binds IgM, but also IgG and IgA; (iv) IgM antibody-mediated enhancement of humoral immune responses, highlighting the importance of complement and its receptors, (v) the numerous important roles of IgM natural antibodies in regulation of inflammation. It is an invaluable resource for researchers and clinicians alike.

Ankylosing spondylitis, the third most common form of chronic arthritis, is a systemic rheumatic disorder characterized by inflam mation of the axial skeleton (spine and sacroiliac joints), and a host of systemic manifestations. With comprehensive care, the vast majority of patients can lead full, productive lives. However, management can succeed only with patient education and exercise. Recent communication from my co-editor, Carson Dick, serves to remind me that there are several unresolved issues concerning drug therapy in ankylosing spondylitis. Clearly, in spite of my views, there are others who do not believe that the non-steroidal anti-inflammatory drugs (NSAIDs) alter favorably the course of disease and they must be administered for prolonged periods and in anti-inflammatry quan tities to be effective. I would agree with Carson Dick that aspirin and phenylbutazone are way down the list of drug priorities following the marketing of other NSAIDs that are effective and safer. I am grateful to my contributors to this volume, all recognized authorities on their particular topic. It has been a privilege col laborating with them on this particular volume. ABOUT THE EDITOR John J. Calabro, MD, is Professor of Medicine and Pediatrics at the University of Massachusetts Medical School and Director of Rheumatology at Saint Vincent Hospital, both in Worcester, Mas sachusetts, USA. He is the author of over 260 scientific articles, including several monographs and a book on arthritis for patients."

Taking a multidisciplinary approach to a common and often frustrating problem for athletes and those with an active lifestyle, this book is the first of its kind, addressing muscular injuries to the posterior leg using an in-depth and expansive style that is uniquely dedicated to ensuring all content is explicitly linked to the practical care of patients with calf pain. It is divided thematically into three sections. The first section covers underlying principles involved in these issues, including anatomy, physiology, pathophysiology of injury and neurophysiology of musculoskeletal pain. Clinical assessment techniques and imaging are covered in the second section. The third section on treatment is the most expansive, discussing acute, sub-acute and chronic posterior leg muscle injuries, as well as surgical management, rehabilitation techniques, complementary medicine and special populations. Overall, the book is designed to use muscular injuries of the posterior leg to as a means to understand the assessment and treatment of muscular injuries more broadly. Taken together, it is the consummate source for orthopedists, doctors in sports medicine, podiatrists, rehabilitation professionals and primary care physicians who treat muscular injuries in the posterior leg, though reader will gain a conceptual and practical framework for the assessment and treatment of muscular injuries in general.

Ideal for shoulder surgeons who want to upgrade their skills to the next level, this practical, step-by-step text presents the latest cutting-edge management strategies and science aimed at shoulder preservation surgery. Highlighting four main areas - the overhead athlete, shoulder instability, glenohumeral arthritis, and the rotator cuff - these innovative techniques focus on the maintenance of the native shoulder joint. Chapters open with an introduction to the clinical problem, followed by misgivings related to open surgery or arthroplasty as treatment strategies. A rationale for the arthroscopic treatment is then presented, along with an in-depth description of the technique itself as well as preliminary results. Techniques presented include posterior capsule release for the overhead athlete, arthroscopic Latarjet for instability, the CAM procedure for glenohumeral arthritis, biological augmentation for rotator cuff repair. A fifth section covers post-operative care and return-to-play considerations. With contributions from many of the top thinkers and surgeons of the shoulder, Elite Techniques in Shoulder Arthroscopy brings these exciting new management strategies to the fore with the aim of elevating them to more common practice for orthopedic surgeons and sports medicine specialists.

This volume is a state-of-the art resource on the recent advances and clinical management of NSAIDs and aspirin. The text provides a thorough overview of NSAIDS and aspirin, reviewing such topics as pharmacology and mechanisms, clinical effects, and the safety and efficacy of these drugs. It also focuses on the effect of the drugs on the cardiovascular system and in the prevention of GI cancer. Practical recommendations for a safe prescription of NSAIDs are also included. Written by experts in the field, NSAIDs and Aspirin: Recent Advances and Implications for Clinical Management is a comprehensive text of great value to gastroenterologists, rheumatologists, cardiologists, oncologists, orthopedists, trauma and internal medicine specialists.

Rheumatology in Practice offers chapters which are organised and built around anatomical and regional syndromes, so reinforcing the evidence-based approach. As readers progress through the text they are given more demanding and challenging questions, encouraging them to use their diagnostic skills to identify the main syndromes and the underlying diseases responsible for the disorders in question. The text is lavishly illustrated in full colour, with detailed photos of patient examinations, complemented by radiographs and full colour line illustrations. The text also benefits from the use of summaries using coloured boxing to identify key points in diagnosis and management. Written by two of the most respected clinicians in the discipline, this book will be essential reading for rheumatologists in practice and training.

Recent research, which Bone- Metabolic Function and Modulators expands on, has added new support to the idea that bone not only serves as a support system, but also functions as an integrating organ, with a significant regulatory role for lipid and energy metabolism. Links between physical activity and the skeleton are also becoming increasingly clear. This fully illustrated volume contains up-to-date information on the metabolic role of the skeleton and what this can mean for the treatment of metabolic as well as skeletal and auditory diseases. Bone- Metabolic Function and Modulators is of particular interest to clinician scientists, clinical and basic bone researchers, orthopedists, endocrinologists, internists, dentists, nurse practitioners, medical and dental residents and physiotherapists as well as students of the musculoskeletal system. Bone- Metabolic Function and Modulators is the seventh volume in the series Topics in Bone Biology, edited by Felix Bronner and Mary C. Farach-Carson. Other titles in this series:- Bone Formation Bone Resorption Engineering of Functional Skeletal Tissues Bone and Osteoarthritis Bone and Cancer Bone and Development Bone- Metabolic Function and Modulators is of particular interest to clinician scientists, clinical and basic bone researchers, orthopedists, endocrinologists, internists, dentists, nurse practitioners, medical and dental residents and physiotherapists as well as students of the musculoskeletal system. Bone- Metabolic Function and Modulators is the seventh volume in the series Topics in Bone Biology, edited by Felix Bronner and Mary C. Farach-Carson. Other titles in this series:- Bone Formation Bone Resorption Engineering of Functional Skeletal Tissues Bone and Osteoarthritis Bone and Cancer Bone and Development Bone- Metabolic Function and Modulators is of particular interest to clinician scientists, clinical and basic bone researchers, orthopedists, endocrinologists, internists, dentists, nurse practitioners, medical and dental residents and physiotherapists as well as students of the musculoskeletal system. Bone- Metabolic Function and Modulators is the seventh volume in the series Topics in Bone Biology, edited by Felix Bronner and Mary C. Farach-Carson. Other titles in this series:- Bone Formation Bone Resorption Engineering of Functional Skeletal Tissues Bone and Osteoarthritis Bone and Cancer Bone and Development

This dictionary provides a comprehensive list of the terms and definitions commonly used in clinical rheumatology and osteology, and the new edition has been extended to include more than 50 additional entries. The book contains systematic descriptions relating to diseases of the locomotor apparatus, including osteoporosis, and important laboratory findings; special reference is made to the immunological parameters, which are essential for correct definition of rheumatologic disorders. Another focus is the general principles of pharmacological treatment, including biologicals and modern therapy. Information is also provided on individual disorders in the field of mineral metabolism and metabolic osteopathies and basic issues in rheumatic surgery. General entries are included from the fields of physical medicine and physiotherapy, including a system of functional assessment. The Dictionary of Rheumatology will be of value for medical students and all who are training in this specialty.

Autoimmune disorders of the skin remain an enigma for many clinicians and scientists not familiar with these mostly severe and chronic diseases. The book provides an overview and the latest information on the broad spectrum of cutaneous autoimmune disorders for clinicians, scientists and practitioners in dermatology, medicine, rheumatology, ENT, pediatrics and ophthalmology. The book is unique since it presents the state-of-the-art knowledge on pathophysiology, clinical diagnosis and management of these disorders provided by the world experts in the field. The primary intention is to broaden the understanding of the pathophysiology of cutaneous autoimmune disorders and to provide a practical guide to how to identify and handle these conditions. The book is illustrated with many tables, illustrative figures and clinical color photographs. The third edition has been thoroughly updated and extended by chapters on paraneoplastic cutaneous syndromes, atopic dermatitis and autoimmunity and Skin manifestations of rheumatic diseases.

Back pain is the commonest form of rheumatism and it is estimated to affect between 65% and 80% of populations sampled. The costs of back pain-related medical care and disability compensation make it one of society's most significant non-lethal medical conditions. Whilst mortality is low, its morbidity is high, inconvenience great, and economic burden massive. The actual symptom of back pain is one of the commonest and most perplexing encountered in medical practice. A proper understanding of what it means is crucial for further medical advance. However, the field of back pain research probably has more experts than any other. Anybody who has back pain will, as often as not, expound views on all matters concerning causation and expectations. Indeed, it is not for a lack of ideas that this field of investigation has failed to make progress. A respected senior investigator advised me early on that patients could not even tell which side their pain was on. It was only many years later that I discovered why. Though the initial incident or accident would seem important to the patient and to the researcher, it is remarkable how little it helps distinguish patterns of back pain. Tests of inappropriate behaviour in the past have been widely disseminated and yet even the originators have said that they cannot be sure of the implications of positive non-organic test findings. This book will show that these 'indicators' are not what they seem to be. In many cases, it is difficult to tell which level in the lumbar spine the pain comes from, and thus treatments such as injections or operation, may be given at the wrong level, let alone the wrong side. Though the various forms of back pain treatment seem to help some patients, when these same treatments are subjected to randomised controlled trials, the evidence for efficacy seems to all but vanish. With all these difficulties and uncertainties, it can be seen why low back pain presents one of the most fallible fields of healthcare. This book indicates that there are ways of dealing with the majority of these problems. Many of the answers from the research conducted were most unexpected. The reader is also advised that the scientific approach cannot deliver hard and fast answers to all contemporary questions in such a wide field and much has depended on the choice of problems to study. Whilst the tests used to distinguish the patterns in this study have their limitations, and whilst there is, as yet, only limited evidence as to the underlying pathology for the patterns recognised, it is felt that some of the other patterns identified are descriptive of diagnoses that are generally accepted. If the answers that are put forward appear to change the direction of understanding, it is hoped that you, the reader, will be able to carry the enquiry further when you see patients, advise treatment or even experience back pain yourself!

Nutritional Influences on Bone Health presents a collection of papers from the 8th International Symposium on Nutritional Aspects of Osteoporosis, the primary forum for and only regular meeting exclusively devoted to the topic of nutritional influences on bone health. The outcome is a fusion of the most current and up-to-date research in this area. Key themes include the permeation of the Western diet across the globe, calcium, vitamin D and acid-base balance. Written by authorities on the impact of nutrition on bone health, Nutritional Influences on Bone Health brings the reader the emerging trends, new messages and the latest scientific data in the field, to inform future research and clinical practice. This comprehensive, well researched volume is an essential reference for professionals in the field of bone health and nutrition.

Review of Rheumatology is a synopsis of key areas of interest, making for an indispensable quick reference work. The material included reviews basic musculoskeletal anatomy, immunology, genetics, major rheumatic diseases and their pathophysiology, and major rheumatic therapeutics, as well as a unique chapter on the emerging autoinflammatory diseases. Review of Rheumatology is a clear and concise review book written in an outline format. This book is a quick and easily accessible reference not only for those preparing for the rheumatology board exams, but it also serves as a succinct reference for all health care workers interested in the field of rheumatology.

A comprehensive reference and practical guide on the technology and application of ultrasound to the musculoskeletal system. It is organized into two main sections. The first is devoted to general aspects, while the second provides a systematic overview of the applications of musculoskeletal ultrasound in different areas of the body. Ultrasound scans are correlated with drawings, photographs, images obtained using other modalities, and anatomic specimens. There is a generous complement of high-quality illustrations based on high-end equipment. This book will acquaint beginners with the basics of musculoskeletal ultrasound, while more advanced sonologists and sonographers will learn new skills, means of avoiding pitfalls, and ways of effectively relating the ultrasound study to the clinical background.

This book provides an updated overview of agammaglobulinemia, a rare form of primary immunodeficiency which is considered the prototype of the congenital humoral defects, and which is characterized by the absence of peripheral B cells and very low serum immunoglobulin levels. The book opens by discussing the highly orchestrated early B cell development in the bone marrow and the genes involved based on both human and animal models. The pathogenesis and clinical presentation of X-linked agammaglobulinemia, caused by mutations in the BTK (Bruton's tyrosine kinase) gene, are then presented in detail, followed by descriptions of the clinical manifestations and molecular basis of the less frequent autosomal recessive and autosomal dominant forms of agammaglobulinemia. Patients' management in terms of respiratory complications, gammaglobulin replacement therapy and the potential value of novel experimental therapeutic strategies are discussed. The book's closing chapters offer a comprehensive and updated description of mutations in the BTK gene, and the expression and function of BTK in cells other than B cells.

This book is dedicated to our readers with the intention of providing an informative exposition of the myositis syndromes. It is also presented in the hope that perhaps it may serve to inspire and stimulate discussion and research into these disabling disorders. Included are descriptions of clinical features, differential diagnosis, pathogenetic mechanisms, and approaches to therapy. Current concepts of classi- cation and diagnostic techniques are also presented. The production staff at Humana Springer, especially Ms. F. Louie and Ms. C. Walsh, have been instrumental and invaluable in allowing this work to see the light of day. Above all, the scholarly essays of the contributing authors are acknowledged with gratitude. They have given this volume its character and existence. New York, NY Lawrence J. Kagen v Contents Preface ...v Contributors ...ix 1 Evaluation of the Patient ...1 Lawrence J. Kagen 2 Classification of Idiopathic Inflammatory Myopathies ...15 Frederick W. Miller 3 The Inflammatory Milieu: Cells and Cytokines...29 Ann M. Reed and Thomas A. Griffin 4 Juvenile Dermatomyositis: An Update on Clinical and Laboratory Findings ...55 Lauren M. Pachman 5 Inclusion Body Myositis ...87 Lawrence J. Kagen 6 The Role of Muscle Biopsy in the Diagnosis of Inflammatory Myopathy ...95 Sakir Humayun Gultekin 7 Electromyography ...1 1 1 Hans L. Carlson 8 Magnetic Resonance Imaging of Myopathies and Myositis ...127 Carolyn M. Sofka 9 Ultrasound in the Evaluation of the Inflammatory Myopathies ...147 Ronald S. Adler and Giovanna Garofalo vii viii Contents 10 Serological Findings ...165 Ira N.

This handbook is an in-depth and comprehensive guide for the treatment and management of patients with juvenile idiopathic arthritis. The handbook provides an informative review of the disease looking at the epidemiology, etiology and pathogenesis, issues of diagnosis and classification, consequences and complications, general treatment aspects, as well as both non pharmacologic and pharmacologic therapy whilst considering the future outlook for patients with juvenile idiopathic arthritis. Juvenile idiopathic arthritis is the most common type of arthritis found in children and adolescents, affecting about 1 in 1,000 children. It is a chronic disease which causes inflammation, pain and swelling of the affected joints and can affect joints in any part of the body. This Handbook provides an unbiased, informative discussion of the current and emerging treatments in this field.

With hundreds of question and answer items and bite-sized chunks of information that can be read and processed easily, reviewing for the pediatric board exams - or just brushing up in your spare time - has never been easier. Pediatric Tricky Topics, Volume 1: A Practically Painless Review includes review items in pediatric orthopedics, trauma, environmental medicine, toxicology, rheumatology, and neurology topics, among others. The Q&A format allows for self-testing or study with a partner or a group and is practical and accessible enough to dip into during a few minutes of downtime at the hospital or office, and as such it is suitable for those studying for the pediatric board exam, practicing physicians brushing up their skills, and any busy clinician who wants to learn more about these topics while on the go.