More than 140 years ago, lupus erythematosus (LE) was recognized as a disease entity by clinicians working in the field of dermatology, which had only recently become an independent medical discipline. Soon after cutaneous lupus was first reported, it was realized that, apart from the skin, the disease could involve other organs and thus be systemic in nature. The latter observations were first made by MORITZ KApOSI [1], whose work has attracted renewed attention re cently and who succeeded FERDINAND VON HEBRA to the chair of dermatology at the Medical Faculty in Vienna. The early description of lupus erythematosus in both its cutaneous and systemic manifes tations was thus intimately associated with Vienna and its Medical School. The next phase in the study of lupus was characterized by an in crease in knowledge of the type and extent of organ involvement. The work by OSLER [2], LIBMANN and SACKS [3], and KLEMPERER [4] best represents these advances. The increase in clinical knowledge of LE finally led to DUBOIS' famous monograph [5], which was pub lished at a time of renewed interest in SLE, elicited by the descrip tion by HARGRAVES et al. [6] of the LE-cell phenomenon. A more detailed analysis of this finding revealed that the disease was charac terized by an abnormal immune response, although its pathogenetic implications were still unclear.

Rheumatic and autoimmune diseases are often present in women during the childbearing years and as such, correct management of pregnancy throughout its course is of significance to all those affected. Previously women with systemic rheumatic diseases were counselled against pregnancy as the majority of medications carried potential or perceived teratogenic risk. But in recent years new therapies have emerged that have advanced treatment. Patients have experienced significant improvements in physical function, quality of life, and reduced damage accrual. As a result, an expanded cadre of health care providers now need to be able to manage pregnancy in women with underlying rheumatic disease, both in acute or chronic settings. Practical Management of the Pregnant Patient with Rheumatic Disease is a quick-access guide of the most up-to-date understanding of the interplay between pregnancy and rheumatic diseases and principles of management before, during and after pregnancy assisting in decision making regarding treatment of women with autoimmune diseases. This collection of 70 cases covers pregnancy counseling, the management of disease flares, thromboembolic disease, the management of patients with end organ disease, advice on medications, obstetric complications, infections and the management of rare diseases in women with rheumatic diseases before and during pregnancy and post-partum. The handbook provides concise recommendations for all providers who may encounter women of child-bearing age including rheumatologists, gynaecologists, paediatricians, primary care providers and health professionals dealing with pre-conceptional and pregnant women with rheumatic diseases.

Offering up-to-date, comprehensive coverage of disease progression, diagnosis, management, and prognosis, Textbook of Pediatric Rheumatology is the definitive reference in the field. For physicians caring for children with rheumatic diseases, this revised 8th Edition is an unparalleled resource for the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents. Global leaders in the field provide reliable, evidence-based guidance, highlighted by superb full-color illustrations that facilitate a thorough understanding of the science that underlies rheumatic disease. Offers expanded coverage of autoinflammatory diseases, plus new chapters on Takayasu Arteritis and Other Vasculitides, Mechanistic Investigation of Pediatric Rheumatic Diseases, Genetics and Pediatric Rheumatic Diseases, and Global Issues in Pediatric Rheumatology. Reflects the changes in diagnosis, monitoring, and management that recent advances have made possible. Covers the latest information on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies, helping you choose treatment protocols based on the best scientific evidence available today. Features exhaustive reviews of the complex symptoms, signs, and lab abnormalities that characterize these clinical disorders. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This book elucidates on the examination technique, the sonographic changes in musculoskeletal rheumatic involvement and the ultrasound assessment of joint rheumatic diseases. The atlas is enriched with several figures, in which the US picture is compared with that of conventional radiography, CT and MRI. It provides a unique collection of black and white and color images for easy and reliable diagnosis. The book is a practice-oriented tool.

Selected as a Doody's Core Title for 2022 and 2023! Imaging in Rheumatology: A Clinical Approach is ideal for radiologists and rheumatologists—as well as orthopedic surgeons and others interested in applying imaging to rheumatologic diseases—and stresses conventional radiography as the most effective imaging assessment technique to help diagnose various diseases and conditions. Greenspan and Gershwin—a radiologist and rheumatologist, respectively—focus on practical, everyday use, so you can apply knowledge you learn in any clinical setting. Features: Clearly and comprehensively details clinical, pathological, and imaging assessment of rheumatic diseases and conditions like arthritides and arthropathies. Trains radiologists learn how imaging fits into diagnostic processes—and non -radiologists how to better understand imaging techniques. Designed for practical, everyday use in clinical situations with patients. Chapters in the core middle section present clinically relevant and practical overviews of a disease or condition, accompanied by illustrated imaging features of that condition. Helps you recognize a disease process masquerading as arthritis. Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac. Take advantage of these practical features that will improve your eBook experience: The ability to download the eBook on multiple devices at one time — providing a seamless reading experience online or offline. Powerful search tools and smart navigation cross-links that allow you to search within this book, or across your entire library of VitalSource eBooks. Multiple viewing options that enable you to scale images and text to any size without losing page clarity as well as responsive design. The ability to highlight text and add notes with one click.

Filled with practical advice from experienced nurses and up-to-date clinical information, this new edition of the Oxford Handbook of Musculoskeletal Nursing is the invaluable guide for all nurses and allied health professionals working with patients who have rheumatological and musculoskeletal conditions. Written to ensure that a nurse in any care environment will have the core information they require at their fingertips, this Handbook is split into three sections: musculoskeletal conditions and their management; clinical issues; and nursing care issues including treatment, nursing management, and tools. Management approaches have been fully updated since the first edition, and the changing healthcare environment and available treatments have been considered, alongside the move towards patient self-management and self-care. This Handbook also addresses the increasing demand for guidance in relation to musculoskeletal conditions, as the growing elderly and chronic disease populations needs for healthcare continue. Featuring brand new chapters on the patient's perspective, nurse-led clinics, and public health awareness, the Oxford Handbook of Musculoskeletal Nursing second edition is a practical and comprehensive guide to help the reader reach the best possible results for their patients.

Psoriatic arthritis, or PsA, is now acknowledged the second most prevalent and important inflammatory arthropathy worldwide. The addition of this new textbook on PsA is a fitting and important inclusion to the Oxford Textbooks in Rheumatology series, written to reflect the significant advances in the field in recent years. With the recent advances in the understanding of pathogenesis, and the development of novel therapies, the Oxford Textbook of Psoriatic Arthritis provides a comprehensive overview of the disease. Each chapter is written by leading clinicians and scientists in the field of psoriatic arthritis, to provide a contemporary view of PsA, and a look into the future directions of research. Covering everything from epidemiology and diagnosis to genetics and pathology, detailed sections on treatment and outcomes provide an invaluable resource for the clinician. The book is also highly illustrated with both clinical images such as x-rays and histological photographs to aid clinical knowledge, and diagrams of the immunology and genetics that underlie the disease. Practical and all-inclusive, with summary boxes to distil the most important information, the Oxford Textbook of Psoriatic Arthritis will prove an invaluable resource for rheumatologists, dermatologists, trainees, and all members of the multidisciplinary team who are interested in recent advances in PsA.

Musculoskeletal foot pathology is endemic in patients with rheumatological conditions, with up to 90% of patients reporting current foot pain. However, foot pathology is often trivialised, despite the strong body of evidence showing foot problems are associated with reduced quality of life. The Foot and Ankle in Rheumatology is a unique, comprehensive, and detailed guide to all aspects of the management of foot and ankle pathologies in rheumatic conditions. Written by a team of leading experts, this title provides international perspectives and current state of the art information on foot and ankle pathology across a range of conditions. With over 170 colour images and photographs, practical diagnostic and management techniques are clearly explained with references to the latest guidelines. Rheumatology is a fast-evolving field, with major advances in treatment and management strategies. As the effective management of rheumatological foot and ankle disorders requires and integrated, disease-stage approach across a multidisciplinary team, the Foot and Ankle in Rheumatology has been designed to provide clear, practical, and evidence-based advice for a wide range of health professions, from podiatrists, rheumatologists, and orthopaedic surgeons to occupational therapists and physiotherapists.

FOODS TO HELP AND HEAL ARTHRITIS - EAT BETTER, FEEL BETTER Hundreds of thousands of people with arthritis have been helped by the Margaret Hills Clinic and by Margaret's bestselling book, Treating Arthritis: The Drug-free Way. This companion title, completely updated with all-new recipes, offers a full range of nutritional resources to bring about an improvement for anyone struggling with pain and mobility. Embracing the simple principles that make this drug-free protocol so effective, this book offers hundreds of recipes and dietary plans, as well as an overview of why diet is so important for managing arthritis. It caters for vegetarians and vegans, and has recommendations for those managing auto-immune conditions such as coeliac disease, or food allergies. There are clean, contemporary and delicious meals for every season, as well as such essentials as smoothies, juices, bone broth and healthful bread recipes. With an emphasis on fresh, raw, local ingredients, the recipes in this book complement the Treating Arthritis programme to offer gentle, natural and manageable steps to reduce pain and improve mobility.

Systemic Lupus Erythematosus (often abbreviated to SLE or lupus) is a systemic autoimmune disease that can affect any part of the body, causing the immune system to attack the body's cells and tissue, and resulting in inflammation and tissue damage. This new addition to the Oxford Rheumatology Library series provides a practical approach to the assessment and management of patients with this complex, multisystem autoimmune disease to improve the diagnosis and treatment of the disease and its complications. It provides comprehensive but easy to assimilate reading for consultant rheumatologists, dermatologists, nephrologists, obstetricians and other specialists and their trainees, interested GPs, specialist nurses, and clinical trial teams both in hospitals and contract research organizations.

Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are related conditions occurring almost exclusively in older people. Polymyalgia rheumatica is considered to be the rheumatic disease that is subject to the widest variations of clinical practice, partially due to the considerable uncertainty related to diagnosis and outcomes. Giant cell arteritis, an inflammatory form of vasculitis, may present with a broad spectrum of clinical manifestations and can be complicated by acute ischemic events, the most serious of which is permanent blindness. Early recognition and adequate treatment of the condition is thus necessary to prevent patients' loss of independence and to maintain their quality of life. Part of the Oxford Rheumatology Library series, Polymyalgia Rheumatica and Giant Cell Arteritis provides quick and practically relevant information on several aspects of the diseases, particularly on diagnosis and management, with the ultimate aim of improving the patient's care. Chapters highlight current concepts of pathogenesis, recent advances of diagnostic and therapeutic approaches, and the ongoing research into the identification of new biomarkers and corticosteroid-sparing medications. Each chapter is complemented with key message boxes highlighting the most relevant information for clinical practice. This concise but comprehensive reference is particularly suited for rheumatologists, general practitioners, and other professionals caring for patients with PMR and GCA.

Gout has become increasingly prevalent in recent years, and is now the most common form of inflammatory arthritis. There have been significant developments in our understanding of the basic biology of gout over the last decade, and major advances in therapeutics have provided successful treatments for acute attacks and long-term prevention, offering clinicians effective treatment options for their patients. Part of the Oxford Rheumatology Library series, Gout provides an up-to-date summary of the pathogenesis, clinical features, and treatment approaches to this condition. The main focus is on key aspects of the biology of the disease, relevant diagnostic tools, and principles of gout management. Practical information is included to guide safe and effective prescribing of gout medications. Chapters on imaging and the future of gout management are also included. The three authors are experts in the basic biology and therapeutics of gout, and have summarized key practice points in a concise and readable manner, making this comprehensive yet practical volume an essential resource for all rheumatologists and general practitioners.

In this concise, accessible, and comprehensive reference, world experts in the field of lymphedema detail all of the non-surgical and surgical approaches to the multidisciplinary management of patients with upper and lower extremity lymphedema. There is particular focus on the surgical treatments for lymphedema, where the reader is taken step-by-step through illustrated guides for each procedure by the leading experts in the field of lymphedema microsurgery; from patient selection, preoperative evaluation, surgical technique, and postoperative management. The book is strictly organized so that readers can quickly find content and provides readers with the necessary tools and framework to readily apply these innovative and state-of-the art techniques to their patients to optimize outcomes of surgical and non-surgical treatments for their lymphedema patients. Each chapter features a standardized content layout with full-color illustrations and clinical photographs to visually represent the content and includes key tips from experts in lymphedema, accompanied by key video contributions from the authors to demonstrate the surgical techniques. There is key emphasis on advances in our understand of the etiology of lymphedema, the most important surgical topics in lymphedema microsurgery, the current evidence available for the surgical treatment of lymphedema, and recent advances in lymphedema including new pharmacological treatments that target inflammation and fibrosis Edited by leaders in lymphedema microsurgery and contributed to by a multidisciplinary group of international experts to provide a full and comprehensive guide, Multimodal Management of Upper and Lower Extremity Lymphedema is aimed at a wide target audience that includes surgeons that perform lymphedema surgeries, other medical specialties that treat patients with cancer, lymphedema therapists, physical therapists, and occupational therapists, as well as nursing specialties and trainees.

Lupus is a disorder in which the body's immune system attacks itself, culminating in disease which can affect multiple organs, including the skin, joints, heart, lungs, kidneys, and central nervous system. Lupus currently affects about 30,000 patients in the UK, 500,000 in the United States and tens of thousands throughout Europe. Whilst there have been great advances in research into the genetic background of lupus and new interventions such as stem-cell transplants, there is still a surprising lack of information available for patients, carers and their families. Written by the former President of the British Society for Rheumatology and the current co-director of the Lupus Center of Excellence in Pittsburgh, USA, this new edition of Lupus: The Facts reflects major developments in our understanding of the causes of lupus.

The muscular dystrophies are a group of genetic diseases that severely affect children and adults. For sufferers and their family, the illness presents enormous physical and psychological challenges. Written specifically for people with muscular dystrophy and their families, this book answers many of the questions asked about how and why muscular dystrophy occurs, and how it will affect the life of a recently diagnosed child.
As well as presenting the reader with advice and an explanation of muscular dystrophy, the book also guides the reader towards further information on societies and support groups around the world, and reliable internet resources. It also contains a full glossary to aid the reader in their understanding of the disease.
The different types of muscular dystrophy are described throughout with a minimum of technical jargon. Questions relating to exercise, physiotherapy, surgery, and the emotional effects of the diseases are answered, and advice is given on the problems of schooling and choice of career.
Since publication of the first edition in 1994, the genes for almost all the different types of dystrophy have been identified, enabling prevention through genetic counselling, therefore relieving some of the worry for affected families. Drawn from his many years of experience treating patients, Professor Emery provides authoritative, yet compassionate advice for people living with this illness.

"Rheumatology, Orthopaedics and Trauma at a Glance" is the new edition of "The Musculoskeletal System at a Glance." The book now includes not just basic anatomy, but also features presenting complaints and patient examination and reflects the increased coverage of rheumatology, making it relevant for students at all levels.

"Rheumatology, Orthopaedics and Trauma at a Glance"Expands its coverage of rheumatology to include all major topics on the medical student curriculumIncludes fully illustrated chapters on examination of each part of the musculoskeletal systemProvides self-assessment case studies to test knowledge and provide clinical contextConsolidates all information relating to the musculoskeletal system in one title

"Rheumatology, Orthopaedics and Trauma at a Glance" is ideal for all medical students studying the musculoskeletal system or taking an orthopaedics or rheumatology rotation.

This book provides a comprehensive overview of the available biologic therapies whilst comparing them to standard disease modifying anti-rheumatic drugs, and discusses how best to determine which therapy is most appropriate for an individual patient in the framework of current guidelines. Biologics for the Treatment of Rheumatoid Arthritis is an up-to-date and concise practical guide to the latest therapeutic developments in this field. This book is an invaluable source of topical information for all rheumatologists and health care professionals treating patients with rheumatoid arthritis.

Allgemeinmediziner, Rheumatologen, Orthopaden, Internisten, Neurologen, Krankengymnasten und Masseure sehen sich nahezu taglich mit den verschiedensten Auspragungen weichteilrheumatischer Erkrankungen und anderen Schmerzsyndromen des Bewegungsapparates konfrontiert. Bei Sheon finden sie eine systematische Darstellung der diagnostischen und therapeutischen Problemloesungen. Die Autoren stellen das jeweils Typische und Wesentliche einer bestimmten Krankheitsform heraus und schliessen daran individuelle Diagnosen und gezielte Therapieempfehlungen an. Das Buch zeugt von einem nuchternen Pragmatismus, der sowohl pathophysiologischen wie pathopsychologischen Faktoren Rechnung tragt.

Ihr praxisnaher Ratgeber fur die Arthroskopie des Kniegelenks! Suchen Sie nach einer klaren und schematischen Darstellung der diagnostischen Arthroskopie? Die voellig neu uberarbeitete zweite Auflage von Die Arthroskopie des Kniegelenks, Diagnostik und Operationstechniken wird Sie nicht enttauschen! Sie informiert umfassend uber die operativen Moeglichkeiten und Techniken bei pathologischen Veranderungen im Knieinnenraum. Verschiedene Arthroskopietechniken werden mit ihren Vor- und Nachteilen ausfuhrlich erlautert. In einem ersten Abschnitt stellen die Autoren die ausseren Voraussetzungen fur die diagnostische Arthroskopie dar. Die endoskopische Anatomie und Pathologie des Kniegelenks wird detailliert beschrieben. Praktische Hinweise zur Ausfuhrung der Arthroskopie stehen hierbei im Vordergrund. Der zweite Abschnitt gilt der operativen Technik. Schritt fur Schritt erfahren Sie, wie welcher pathologische Befund am besten behandelt werden sollte. Probleme und Komplikationsmoeglichkeiten der arthroskopischen Chirurgie im Hinblick auf die einzelnen Techniken sind ebenfalls wichtiger Bestandteil der Ausfuhrungen. Diese zweite Auflage hat mit der ersten nur noch wenig gemeinsam! Sollten Sie die erste bereits kennen, werden Sie jetzt eine erhebliche Erweiterung und noch klarere Darstellung des diagnostischen Teils vorfinden. Der operative Teil entspricht dem jungsten Stand der Technik. Sie erhalten eine aktuelle Darstellung der Arthroskopie des Kniegelenks.

Aktuell und umfassend Schneller UEberblick Praktische Anleitung Minimal-invasive Verfahren werden immer haufiger angewendet. Wer in diesem dynamischen Bereich up-to-date sein moechte, muss sich grundlich mit den Verfahren auseinandersetzen. Kein Problem mit dem neuen Praxis-Leitfaden und Nachschlagewerk. Hier koennen Sie sich schnell und gezielt uber alle wichtigen minimal-invasiven Verfahren informieren: von "Kopf bis Fuss": Wirbelsaule, Schulter und Oberarm, Ellenbogen, Unterarm, Hand und Finger, Hufte, Becken und Oberschenkel, Kniegelenk und Unterschenkel von A bis Z: Oberflachenanatomie, Indikation/Kontraindikation, diagnostisches Vorgehen, technisches Equipment, Landmarken/Lagerung, OP-Ablauf, Varianten und Besonderheiten, Nachbehandlung Schritt fur Schritt: Alle Verfahren sind einheitlich gegliedert und durch umfangreiches Abbildungsmaterial erklart. Das sorgt fur rasche Orientierung und erleichtert systematisches Vorgehen. Damit hat das Werk alles, was Sie benoetigen, um moderne minimal-invasive Techniken kennenzulernen, zu bewerten, sicher anzuwenden und Ihren Patienten zu erklaren.

Die Mikrogefasschirurgie spielt bei Gewebetransplantationen eine immer groessere Rolle. Dieses Buch ist ein "Gewusst-wie"-Text uber die mikrovaskulare Rekonstruktionschirurgie, das vorwiegend von einem einzelnen Chirurgen geschrieben wurde. Es richtet sich sowohl an den erfahrenen als auch an den noch in der Ausbildung befindlichen Chirurgen. Das Buch ist in zwei Abschnitte gegliedert. Der erste beschreibt die operative Anatomie und Technik, die mit der Hebung jedes freien Gewebetransfers verbunden ist. Der zweite Teil behandelt die Anwendung dieser Transplantate fur die Rekonstruktion in drei anatomischen Regionen, in denen die rekonstruktive Mikrochirurgie bedeutende Ergebnisse geliefert hat: Kopf, Hals sowie obere und untere Extremitat. Das Buch ist ein aktuelles Nachschlagewerk fur jeden auf diesem Gebiet arbeitenden Chirurgen, Orthopaden und Traumatologen.

Das hier vorliegende Standardwerk uber die Navigation und Robotic in der Gelenk- und Wirbelsaulenchirurgie wendet sich vor allem an Orthopaden, Unfallchirurgen und Neurochirurgen. Keine Entwicklung in der Orthopadie und der Unfallchirurgie wurde in den letzten Jahren so kontrovers diskutiert wie die Entwicklung von EDV-gestutzten OP-Systemen. Werden sie einerseits aus forensischen Grunden mehr und mehr gefordert (u.a. bei Pedikelschrauben an HWS und BWS), so wird andererseits ihr Nutzen noch diskutiert. Einigkeit besteht sowohl uber die intraoperative Prazision der Systeme, als auch uber die deutliche Verbesserung und Erleichterung der Orientierung bei Anomalien und schweren Deformitaten. Mit grosser Sicherheit werden Navigation und Robotic kunftig einen wesentlichen Stellenwert bei vielen Gelenk- und Wirbelsaulenoperationen haben.