Demonstrates the conditions under which a 2D-LC method should be
considered as an alternative to a 1D-LC method. Establishes a sound
fundamental basis of the principles of the technique, followed by
guidelines for method optimization. Provides a single source for
technical knowledge advances and practical guidance described in
recent literature. Assists with the initial decision to develop a
2D-LC method. Guides the reader in developing a high-quality method
that meets the needs of their application.
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