Basic Aspects of Catechol-O-Methyltransferase and the Clinical Applications of its Inhibitors, Volume 95 (Hardcover, 94th edition)

Volume 95 of "International Review of Neurobiology" focuses on Catechol-O-methyltransferase inhibition, and its clinical application in relation to Parkinson s disease. Chapters cover COMT gene and proteins, L-dopa treatment in Parkinson s disease, the latest research on COMT inhibitors and their clinical applications, as well as future prospects for their use.

Up-to-date summary of biochemistry and pharmacology of COMT and its inhibitors Preclinical models in COMT inhibitor devlopment Transgenic COMT mice latest information summarized Chemistry of COMT inhibitors and their design with molecular modelling COMT gene and its regulation and relation to dopamine related diseases Role of cofactor SAM regulation in relation to homocysteine Nonclinical and clinical safety of COMT inhibitors summarized Future prospects of COMT inhibitors in Parkinson s disease

General

Imprint:	Academic Press Inc
Country of origin:	United States
Series:	International Review of Neurobiology
Release date:	December 2010
First published:	December 2010
Volume editors:	Erkki Nissinen
Dimensions:	229 x 152 x 19mm (L x W x T)
Format:	Hardcover
Pages:	336
Edition:	94th edition
ISBN-13:	978-0-12-381326-8
Categories:	Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences Books > Academic & Education > Professional & Technical > Neuroscience
LSN:	0-12-381326-3
Barcode:	9780123813268

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