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Books > Social sciences > Psychology > Physiological & neuro-psychology
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Ketamine - From Abused Drug to Rapid-Acting Antidepressant (Hardcover, 1st ed. 2020)
Loot Price: R4,667
Discovery Miles 46 670
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Ketamine - From Abused Drug to Rapid-Acting Antidepressant (Hardcover, 1st ed. 2020)
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This book presents the latest data from basic research and clinical
trials supporting the effectiveness of ketamine as a treatment for
depression, bipolar disorder, and suicidal behavior, setting these
positive findings within the context of the serious problem of
ketamine abuse. The first part of the book focuses on the evidence
regarding ketamine abuse, with specific reference to Asian
countries, and discusses countermeasures and complication
management. It then addresses the mechanisms underlying the
antidepressant and side effects of ketamine, which have remained
elusive, describing and discussing important new research findings.
Further, it explains insights gained from whole brain imaging in
rodents and from behavioral pharmacology, and presents evidence
regarding the role of gut microbiota, the NMDA receptor GluN2D
subunit, and the lateral habenula in the actions of ketamine. These
advances form the basis for the safer use of ketamine in patients
with treatment-resistant depression and are expected to lead to the
development of new antidepressants.
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