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Single-Molecule Science - From Super-Resolution Microscopy to DNA Mapping and Diagnostics (Hardcover)
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Single-Molecule Science - From Super-Resolution Microscopy to DNA Mapping and Diagnostics (Hardcover)
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Single Molecule Science (SMS) has emerged from developing, using
and combining technologies such as super-resolution microscopy,
atomic force microscopy, and optical and magnetic tweezers,
alongside sophisticated computational and modelling techniques.
This comprehensive, edited volume brings together authoritative
overviews of these methods from a biological perspective, and
highlights how they can be used to observe and track individual
molecules and monitor molecular interactions in living cells.
Pioneers in this fast-moving field cover topics such as single
molecule optical maps, nanomachines, and protein folding and
dynamics. A particular emphasis is also given to mapping DNA
molecules for diagnostic purposes, and the study of gene
expression. With numerous illustrations, this book reveals how SMS
has presented us with a new way of understanding life processes. A
must-have for researchers and graduate students, as well as those
working in industry, primarily in the areas of biophysics,
biological imaging, genomics and structural biology.
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