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Modeling and Parameter Estimation in Respiratory Control (Paperback, Softcover reprint of the original 1st ed. 1989)
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Discovery Miles 29 460
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Modeling and Parameter Estimation in Respiratory Control (Paperback, Softcover reprint of the original 1st ed. 1989)
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Experimentalists tend to revel in the complexity and
multidimensionality of biological processes. Modelers, on the other
hand, generally look towards parsimony as a guiding prin ciple in
their approach to understanding physiological systems. It is
therefore not surprising that a substantial degree of
miscommunication and misunderstanding still exists between the two
groups of truth-seekers. However, there have been numerous
instances in physiology where the marriage of mathematical modeling
and experimentation has led to powerful in sights into the
mechanisms being studied. Respiratory control represents one area
in which this kind of cross-pollination has proven particularly
fruitful. While earlier modeling ef forts were directed primarily
at the chemical control of ventilation, more recent studies have
extended the scope of modeling to include the neural and mechanical
aspects pertinent to respiratory control. As well, there has been a
greater awareness of the need to incorpo rate interactions with
other organ systems. Nevertheless, it is necessary from time to
time to remind experimentalists of the existence of modelers, and
vice versa. The 4th Annual Biomedical Simulations Resource (BMSR)
Short Course was held in Marina Del Rey on May 21-22,1989, to
acquaint respiratory physiologists and clinical researchers with
state-of-the art methodologies in mathematical modeling, experiment
design and data analysis, as well as to provide an opportunity for
experimentalists to challenge modelers with their more recent
findings."
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