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Autophagy in tumor and tumor microenvironment (Hardcover, 1st ed. 2020)
Loot Price: R2,890
Discovery Miles 28 900
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Autophagy in tumor and tumor microenvironment (Hardcover, 1st ed. 2020)
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This book deals with the paradoxical role of autophagy in tumor
suppression and tumor promotion in cancer cells. Autophagy plays
opposing, context-dependent roles in tumors; accordingly,
strategies based on inhibiting or stimulating autophagy could offer
as potential cancer therapies. The book elucidates the
physiological role of autophagy in modulating cancer metastasis,
which is the primary cause of cancer-associated mortality. Further,
it reviews its role in the differentiation, development, and
activation of multiple immune cells, and its potential applications
in tumor immunotherapy. In addition, it examines the effect of
epigenetic modifications of autophagy-associated genes in
regulating tumor growth and therapeutic response and summarizes
autophagy's role in the development of resistance to a variety of
anti-cancer drugs in cancer cells. In closing, it assesses
autophagy as a potential therapeutic target for cancer treatment.
Given its scope, the book offers a valuable asset for all
oncologists and researchers who wish to understand the potential
role of autophagy in tumor biology.
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