This is by far the most exhaustive biography on Niels Stensen, anatomist, geologist and bishop, better known as "Nicolaus Steno". We learn about the scientist's family and background in Lutheran Denmark, of his teachers at home and abroad, of his studies and travels in the Netherlands, Belgium, France, Italy, Austria, Hungary, Bohemia and Germany, of his many pioneering achievements in anatomy and geology, of his encounters with Swammerdam, Malpighi and with members of the newly established Royal Society of London and the Accademia del Cimento in Florence, and with the philosopher Spinoza. It further treats Stensen's religious conversion. The book includes the full set of Steno's anatomical and geological scientific papers in original language. The editors thoroughly translated the original Latin text to English, and included numerous footnotes on the background of this bibliographic and scientific treasure from the 17th century.

This new volume provides a concise overview of the most basic and exciting chapters of comparative medicine with regards to physiology and function in healthy individuals. The book includes core concepts in anatomy and physiology in human and animal models, which are key to understanding comparative medicine and to making contributions to research in this area. While writing this book, the authors were in constant interdisciplinary dialogue. They aim to contribute to improvements in quality of life for human and animal patients.

The Micro-Tomographic Atlas of the Mouse Skeleton provides a unique systematic description of all calcified components of the mouse. It includes about 200 high resolution, two and three dimensional m CT images of the exterior and interiors of all bones and joints. In addition, the spatial relationship of bones within complex skeletal units is also described. The images are accompanied by detailed explanatory text, thus highlighting special features and newly reported structures. The Atlas fulfils an emerging need for a comprehensive reference to assist both trained and in-training researchers.

The essentials of medical terminology for the short, self-paced, or online course Medical Terminology Express + Medical Language Lab work together to create an immersive, multimedia experience for students and complete teaching materials for instructors that are perfect for a short course in the classroom or online. The text leads students to proficiency through proven word-building and competency-based techniques, while the online program, Medical Language Lab, tracks student progress until they've mastered the language of medicine. An access code inside new, printed texts unlocks the ebook and Medical Language Lab for students. Digital access can be purchased directly on FADavis.com. Instructors. Want to learn more? Request preview access to explore Medical Language Lab. See what students are saying online about the previous edition... Five Stars. "Just the book I needed for class with the Medical Language Lab online that I needed." - Josh, Online Reviewer Fantastic. " ...really easy to understand. I love the color coding, simple language, repetition, and regular practice questions. The online component of the book is also really helpful and well done, highly recommend using it." - Sam, Online Reviewer TextNow in its 3rd Edition, Medical Terminology Express adapts Barbara Gylys's proven word-building techniques for the short-course. Organized by body system, this text demonstrates the connection between anatomical structures and associated medial word roots. Medical Language Lab Online. Interactive. Progressive. Medical Language Lab guides students step by step from basic through advanced levels of proficiency to become confident medical language speakers. A wealth of audio case studies, progressive exercises, lecture videos, and a pronunciation guide and activities, plus an integrated e-book version of the text, offer multiple paths to learning success. This immersive, multimedia experience guides students and tracks their progress as they apply word-building concepts for practice and application.

The Understanding the Stomach chart presents an overview of a major component of the digestive system. The internal structure of the stomach and stomach lining are covered, as well as common disorders. Heavy cover stock with protective varnish for durability.

This image-rich book explores the practice as well as the theory of visual representation and presents us with the importance of designing appropriate images for communication to specific target audiences. This includes the appropriate choice of high-tech digital or low-tech analogue technologies in image-making for communication within the medical education, biological research and community health contexts. We hear from medical students about the value of using clay modelling in their understanding of anatomy, from educators and curriculum designers about visual affordances in medical education and from a community-driven project in South Africa about their innovative use of locally designed images and culture-specific narratives for communicating important health information to marginalised communities. A chapter explores the evolution of scientific visualisation and representation of big data to a variety of audiences, and another presents the innovative 3D construction of internal cellular structures from microscopic 2D slices. As we embrace blended learning in anatomy education, a timely chapter prompts us to think further about and contribute to the ongoing discourse around important ethical considerations in the use and sharing of digital images of body donors. This book will appeal to educators, medical illustrators, curriculum designers, post-graduate students, community health practitioners and biomedical researchers.

The year 1818 saw the publication of one of the most influential science-fiction stories of all time. Frankenstein: Or, Modern Prometheus by Mary Shelley had a huge impact on gothic horror and science-fiction genres, and her creation has become part of our everyday culture, from cartoons to Hallowe'en costumes. Even the name 'Frankenstein' has become a by-word for evil scientists and dangerous experiments. How did a teenager with no formal education come up with the idea for an extraordinary novel such as Frankenstein?

Clues are dotted throughout Georgian science and popular culture. The years before the book's publication saw huge advances in our understanding of the natural sciences, in areas such as electricity and physiology, for example. Sensational science demonstrations caught the imagination of the general public, while the newspapers were full of lurid tales of murderers and resurrectionists.

Making the Monster explores the scientific background behind Mary Shelley's book. Is there any science fact behind the science fiction? And how might a real-life Victor Frankenstein have gone about creating his monster? From tales of volcanic eruptions, artificial life and chemical revolutions, to experimental surgery, 'monsters' and electrical experiments on human cadavers, Kathryn Harkup examines the science and scientists that influenced Shelley, and inspired her most famous creation.

Anatomy questions are asked in all parts of the FRCA examinations, and for many trainees it is a particularly daunting part of the exams. This important new book provides a comprehensive, exam-orientated clinical anatomy book for anaesthetists preparing for all parts of the FRCA. It covers all body regions, relating underlying anatomy to practical procedures and anatomical principles, spanning the breadth of the curriculum and comprising exam-style questions: a chapter of SAQ questions, one of OSCE stations, one of SOE questions and one of MCQs. The text is highly illustrated in full colour with ultrasound images, diagrams and photographs of cadaveric material and models. This is the first anatomy book specifically orientated for the FRCA exam, making it an essential resource for anaesthetists preparing for all parts of the FRCA examination.

Abrahams' and McMinn's Clinical Atlas of Human Anatomy, 8th Edition delivers the straightforward visual guidance you need to perform confidently in all examinations and understand spatial relationships required during your medical training, while also acquiring the practical anatomical knowledge needed for your future clinical career. Respected authority Prof. Peter Abrahams and his team of leading international anatomists and radiologists link a vast collection of clinical images to help you master all the essential correlations between the basic science of anatomy and its clinical practice. See what to look for and how to proceed thanks to an unsurpassed collection of labelled dissection photographs, supported by clear, explanatory diagrams and modern imaging Correlate anatomy to clinical practice with a wealth of MR, CT, DSA, radiographic, endoscopic, and operative images that demonstrate how structures are viewed today in the clinical setting Thoroughly revised and updated throughout, including: brand new dissections, to further improve clarity and consistency throughout the book in every region all new colour overlays added to selected dissections making it even easier to identify key nerves, arteries, veins and especially lymphatics fully revised neuroanatomy content reflects the latest understanding of functional neuroanatomy as seen with modern 3D and functional imaging updated and coloured and a unique lymphatics section Includes access to the complete, enhanced eBook - unlocking a huge, carefully-selected collection of BONUS CLINICAL material, integrated throughout on almost every page to enhance your study and help make those essential clinical / anatomical connections. This sets Abrahams' and McMinn's apart from any other atlases of human anatomy! 200+ 3D scans,- allowing you to view the body in a more dynamic way to aid your understanding of dynamic anatomy. Master the 500 clinical conditions every physician should know by reviewing the associated clinical topics - featuring over 2000 additional clinical photos, radiological images, and case presentations not found in the printed book. Learn from the culmination of over 45 years international clinical experience of Prof. Abrahams and over 100 of his colleagues worldwide who have contributed to this unique collection of clinical anatomy images.

This book brings together current advances in high-technology visualisation and the age-old but science-adapted practice of drawing for improved observation in medical education and surgical planning and practice. We begin this book with a chapter reviewing the history of confusion around visualisation, observation and theory, outlining the implications for medical imaging. The authors consider the shifting influence of various schools of philosophy, and the changing agency of technology over time. We then follow with chapters on the practical application of visualisation and observation, including emerging imaging techniques in anatomy for teaching, research and clinical practice - innovation in the mapping of orthopaedic fractures for optimal orthopaedic surgical guidance - placental morphology and morphometry as a prerequisite for future pathological investigations - visualising the dural venous sinuses using volume tracing. Two chapters explore the use and benefit of drawing in medical education and surgical planning. It is worth noting that experienced surgeons and artists employ a common set of techniques as part of their work which involves both close observation and the development of fine motor skills and sensitive tool use. An in-depth look at police identikit construction from memory by eyewitnesses to crimes, outlines how an individual's memory of a suspect's facial features are rendered visible as a composite image. This book offers anatomy educators and clinicians an overview of the history and philosophy of medical observation and imaging, as well as an overview of contemporary imaging technologies for anatomy education and clinical practice. In addition, we offer anatomy educators and clinicians a detailed overview of drawing practices for the improvement of anatomical observation and surgical planning. Forensic psychologists and law enforcement personnel will not only benefit from a chapter dedicated to the construction of facial composites, but also from chapters on drawing and observation.

Biomedical scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without biomedical scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible. The Fundamentals of Biomedical Science series is written to reflect the challenges of practicing biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis. Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed - from microbiology to cytopathology to transfusion science. Alongside volumes exploring specific biomedical themes and related laboratory diagnosis, an overarching Biomedical Science Practice volume gives a grounding in the professional and experimental skills with which any Biomedical Scientist must be equipped. The series: * Understands the complex roles of Biomedical Scientists in the modern practice of medicine * Understands the development needs of employers and the Profession * Addresses the need for understanding of a range of fundamental sciences in the context of Biomedicine * Places the theoretical aspects of Biomedical Science in their practical context The series is developed in partnership with and endorsed by the Institute of Biomedical Science. Visit www.ibms.org for more information. Cell Structure and Function describes the structural and functional features of the various types of cell from which the human body is formed. Focusing on normal cellular structure and function, it gives students and trainees a firm grounding in the appearance and behaviour of healthy cells and tissues on which can be built a robust understanding of cellular pathology. With cell structure and function correlated with clinical contexts throughout, Cell Structure and Function is the ideal introduction to cellular biology for any student of biomedical science. Online Resource Centre The Online Resource Centre to accompany the Fundamentals of Biomedical Science series features: For registered adopters of the book: * Figures from each book, available to download For students: * An interactive Virtual Microscope, encouraging the exploration of tissue samples * Video podcasts including interviews with practicing biomedical scientists, and 'in the lab' footage showing biomedical science in practice

The term cytoskeleton in muscle and nonmuscle cells refers to fibrous proteins that are directly or indirectly associated with cell shape, contractility, and/or motility. These cytoskeletal elements include microtubules and associated proteins, microfilaments and their binding proteins, and lastly, intermediate filaments. Even though the structure and function of myosin and tro- pomyosin have been extensively investigated in muscle ceIls, considerably less is known about their functions in nonmuscle ceIls; they are often referred to generically as actin-binding proteins, as are a-actinin, filamin, vinculin, and others. Indeed, most nonmuscle researchers are unaware that the term intermedi- ate filament was derived from the observation that the diameter of intermedi- ate filaments is intermediate between those of actin (5 nm) and myosin (15 nm) and not intermediate between those of actin (5 nm) and microtubules (25 nm). It has therefore been the purpose of this series to attempt to bridge the communication gap that appears to exist between muscle and nonmuscle researchers. For those students and active scientists who are faced with the task of absorbing new data and concepts at an ever-accelerating rate, review essays are an excellent way to keep up. The essays in this volume, as weIl as in the previous ones, focus on topics of current interest. They are intended to be critical rather than exhaustive.

A Photographic Atlas for Anatomy & Physiology is a new visual lab study tool that helps students learn and identify key anatomical structures. Featuring photos from Practice Anatomy Lab (TM) 3.0 and other sources, the Atlas includes over 250 cadaver dissection photos, histology photomicrographs, and cat dissection photos plus over 50 photos of anatomical models from leading manufacturers such as 3B Scientific (R), SOMSO (R), and Denoyer-Geppert Science Company. The Atlas is composed of 13 chapters, organized by body system, and includes a final chapter with cat dissection photos. In each chapter, students will first explore gross anatomy, as seen on cadavers and anatomical models, and then conclude with relevant histological images.

This book is in many ways a sequel to The Biochemistry ojGlycoproteins and Proteoglycans. The enormous recent progress in understanding the biological roles of glycoproteins has prompted the present volume. The reasons for studying glycoproteins have multiplied, and in the present volume the roles played by glycoproteins are explored in a variety of biological situations. The first two chapters describe molecules involved in cell-substratum and cell-cell interactions in a broad sense, and also focus on recent progress in identifying specific attachment molecules. Our understanding of how normal processes, such as cellular differentiation and tissue organization, are regulated is dependent on understanding how cells interact with the extracellular matrix. When these processes go awry the consequences can be tragic, for example, when manifest as birth de fects and cancer. Our ability to devise appropriate therapies is in many cases limited by our understanding of such cell-matrix interactions. The third chapter explores the roles by glycoproteins during early mammalian development. The carbohydrate portions c1early play very important roles in presenting information during early embryogenesis, and an unusual tumor stern cell, the embryonal carcinoma, looks very promising in pro viding an experimental system for understanding how the expression of these complex carbohydrate determinants is regulated. The next three chapters explore the biology of glycoproteins in distinct situations: in the immune system, in the nervous system, and during erythropoiesis."

Ion channels allow us to see nature in all its magnificence, to hear a Bach suite, to smell the aroma of grandmother's cooking, and, in this regard, they put us in contact with the external world. These ion channels are protein molecules located in the cell membrane. In complex organisms, cells need to communicate in order to know about their metabolic status and to act in a coordinate manner. The latter is also accomplished by a class of ion channels able to pierce the lipid bilayer membranes of two adjacent cells. These intercellular channels are the functional subunits of gap junctions. Accordingly, the book is divided in two parts: the first part is dedicated to ion channels that look to the external world, and the second part is dedicated to gap junctions found at cell interfaces. This book is based on a series of symposia for a meeting on ion channels and gap junctions held in Santiago, Chile, on November 28-30, 1995. The book should be useful to graduate students taking the first steps in this field as well as a reference for the aficionado. The aim of the meeting was mainly to show the impact of various modern techniques, including cell biology, molecular biology, biophysics, and molecular genetics techniques in the study of these ubiquitous intrinsic membrane proteins. Molecular-genetics techniques paved the road to the manipulation of the channel forming molecules.

Epithelial cells are present in many different tissues in the body, and possess a diverse number of functional properties. However, all epithelial cells share some common characteristics. The cells possess a morphological polarity (an-apical and basolateral surface), and are interconnected by tight junctions. The epithelial cells also possess the capacity to transport select solutes across the monolayer. Transport systems localized on either the apical or basolateral surface are respon sible for this vectorial transport. Such characteristics of epithelial cells can be examined in the tissue culture situation. This volume discusses the use of cell culture techniques to study these fundamental properties of epithelial cells. Ma jor questions concerning epithelia which may be examined in culture are ad dressed. The approaches which are taken to answer these questions are described in detail with regards to kidney cell cultures. Similar investigations may be done with epithelial cell cultures derived from other tissues, following the kidney cell culture paradigm."

This volume contains papers that were presented and discussed at The 1996 Interna tional Symposium on Programmed Cell Death, which was held in the Shanghai Science Center of the Chinese Academy of Sciences on September 8-12, 1996. Apoptosis has attracted great attention in the past several years. This is reflected in part by the exponential increase in the number of papers published on the subject. While several major scientific conferences have been held in recent years, this meeting repre sents the first major international scientific meeting on programmed cell death held in Asia, where fast economic growth promises a bright future for both basic and applied re search in biomedical sciences. We organized the meeting with the belief that such a gath ering would foster a closer interaction between scientists from the West and those in Asia. Research on programmed cell death has expanded so extensively that no one meet ing can cover all the important subjects related to apoptosis. The Shanghai meeting fo cused on several key areas ranging from well-established ones, such as cell death in the immune system, to emerging ones, such as the role ofECM in regUlating cell fate. Specifi cally, the subjects presented and discussed included programmed cell death during devel opment, the regulation and biochemical mechanisms of lymphocyte apoptosis, the involvement of extracellular matrix and its remodeling in programmed cell death, genes that cause or prevent cell death, and the application of apoptosis toward cancer therapy."

This volume, the sixth of the series, represents the natural counterpart of the previous volume, Ultra structure of the Digestive Tract. Unlike the latter, however, whose contents fell entirely within the domains of gastroenterology, Ultrastructure of the Extraparietal Glands of the Digestive Tract encom passes a few cognate sciences, such as hepatology, pancreatology, and even oral biology, which are usually dealt with separately. This allows, starting from cell biology, embryology, and comparative anatomy, a comprehensive survey of organs that have much in common both structurally and functionally. The chapters of this book have been compiled by well-known experts in the field with the aim not only of reviewing and pointing out the state of the art of the subject covered, but also of giving directions for future work. Furthermore, through the integration of electron microscopy with immunocytochemistry, autoradiography, freeze fracture, maceration, enzymatic digestion, etc., and by providing superb illus trative material, the authors substantiate the pivotal role played by modern morphology in under standing human physiology and pathology. In fact, it must be stressed, that a consistent part of the tissues studied here are from human origin. We believe that this volume should be read, not only by scientists and teachers active in the field, but also by a larger audience of students and professionals interested in knowing the scientific foundations of biomedicine."

Biomechanics of the Brain will present an introduction to brain anatomy for engineers and scientists. Experimental techniques such as brain imaging and brain tissue mechanical property measurement will be discussed, as well as computational methods for neuroimage analysis and modeling of brain deformations due to impacts and neurosurgical interventions. Brain trauma between the different sexes will be analyzed. Applications will include prevention and diagnosis of traumatic injuries, such as shaken baby syndrome, neurosurgical simulation and neurosurgical guidance, as well as brain structural disease modeling for diagnosis and prognosis. This book will be the first book on brain biomechanics. It will provide a comprehensive source of information on this important field for students, researchers, and medical professionals in the fields of computer-aided neurosurgery, head injury, and basic biomechanics.

Anatomy for Dental Students, Fourth Edition, demonstrates and explains all the anatomy needed for a modern dentistry undergraduate course. This text covers developmental anatomy, the thorax, the central nervous system, and the head and neck with an emphasis on the practical application of anatomical knowledge. This new edition has been extensively revised and updated in line with contemporary teaching and dental practice. Over 300 new full colour diagrams map all the anatomical regions that dental students need to know, while the lively and accessible text guides the reader's learning. Throughout Clinical Application Boxes demonstrate how the form and function of anatomy have consequences for clinical practice. Side-lines boxes contain additional descriptions for key anatomical structures. This text is supported by an Online Resource Centre with multiple choice questions, drag and drop figure exercises, and links to key resources to help readers to consolidate and extend their knowledge of anatomy. Anatomy for Dental Students brings together anatomical structure, function, and their relationship to clinical practice, making ideal for today's dental students.

Venous valves rank among the smallest and most delicate organs of the human and animal bodies - so why devote an entire book to them? We were induced to do so by several reasons. First of all we would point out the clinical significance of venous valves. In the pathogenesis of a number of widespread diseases, such as varicose veins or the post-thrombotic syndrome, venous valves are involved as the underlying cause or at least a factor contributory to the symptoms. According to Taheri et al. these venous diseases occur ten times more frequently than arterial obliterations. Incompetence of venous valves also plays a causal role in varicocele, the most frequent cause of male infertility. But not only pathogenetic reasons induced us to write this book. In more recent times there has been a growing tendency to reconstruct functional valve disorders therapeutically; several surgical methods have been developed, which are critically reviewed in this book. It was our aim to sum up existing knowledge with respect to structure and function of venous valves and to expand that knowl edge by findings of our own. Examinations of semi-thin sections and unilayered en-face preparations have hardly been published so far, and systematic studies of the ultrastructure by electron-microscopy were not to be found in the literature. We are very grateful, therefore, to Dr. Silvana Geleff for having undertaken such a study upon our suggestion."

To create a forum for scientists and clinicians interested in degenerative retinal diseases, we began in 1984 to organize a biennial symposium on Retinal Degeneration as a satellite meeting of the International Congress of Eye Research. The timing and varying location of these meetings provides an important assembly for investigators from throughout the world to convene for presentation of their new findings on the causes and potential therapies for degenerative retinal disorders. The VIII International Symposium on Retinal Degeneration was held from July 28-25, 1998, at the Hotel Vier Jahreszeiten in Schluchsee, a small town in the Black Forest of southwestern Germany. Most of the participants in this meeting contributed to this volume, and we are appreciative of the efforts of each author in making this publication possible. The research presented at the meeting, and described in this proceedings volume, reflects a strong emphasis on the molecular genetic approach to understa- ing these disorders. Several of the papers provide important new insights into the mechanism of photoreceptor degeneration and cell death. A number of the studies are targeted at retarding or reversing the degeneration process. Included for the first time are presentations from all the principal laboratories involved in the field of visual prostheses-implant (chip) technology-in which investigations are targeted at restoring vision in eyes that have lost photoreceptor cells. A variety of diagnostic, clinical, histopathological, and physiological assessments of retinal degeneration in patients are also included.