Die Bedeutung der Hand liegt gewissermassen auf der Hand: Ohne dieses Wunderwerk an Prazision und Empfindsamkeit, an Kraft und Sanftheit, an Ausdrucksfahigkeit und Steuerbarkeit auszukommen, ware fur die meisten von uns kaum vorstellbar. So selbstverstandlich ist uns ihr Gebrauch und sind uns ihre Fahigkeiten, dass wir selten hinterfragen, wie die Hand eigentlich genau funktioniert und wo uberall in unserer Kultur, unserer Sprache und unserem sozialen Miteinander sie ihre Spuren hinterlassen hat. Das "Hand-Buch" geht diesen Fragen nach. Renommierte Autoren spannen dabei einen Bogen, der von der evolutionaren Entwicklung der Greifhand bis zum technischen Design von Roboterhanden, vom engen Zusammenhang von Hand und Gehirn bis zu den vielfaltigen Verbindungen zwischen Hand und Sprache, von musikalischen Fingerfertigkeiten bis zum Handlesen reicht. Biologie, Medizin und Philosophie reichen sich in diesem Buch die Hande, und die Faszination fur die Hand wird durch das handfeste Wissen, das es vermittelt, nur noch grosser. Zu den Autoren des Bandes zahlen renommierte Wissenschaftler aus verschiedenen natur- und geisteswissenschaftlichen Disziplinen, unter anderem Niels Birbaumer (Tubingen, Biopsychologie), E. Altenmuller (Hannover, Musikphysiologie), Helge Ritter (Bielefeld, Neuroinformatik), Bruno Preilowski (Tubingen, Hemispharenforschung), Friedhart Klix (Berlin, Evolutionspsychologie) und Peter Janich (Marburg, Philosophie)."

The essential guide to anatomy and physiology for nursing students. The new edition of Essentials of Anatomy and Physiology for Nursing Practice brings together text, video, full-colour illustrations, interactive activities, and more, to provide nursing students with a comprehensive introduction to understanding the healthy functioning of the human body. This second edition has been thoroughly updated and includes new videos, improved online support, revised learning activities, and clear explanations that will help nursing students feel confident when learning anatomy and physiology for the first time. Key Features: Students can use their phone or tablet to scan QR codes throughout the book and instantly watch informative animations, mini-tutorials, and other useful videos. Introduces all the essential anatomy and physiology information in a carefully structured way, helping students to steadily build their knowledge and successfully apply it to nursing practice. All content is based around the person-centred nursing framework and a fictional family is used throughout to demonstrate how the biology applies to real people, helping students to apply the A&P knowledge directly to real-life nursing situations. Supported by new and improved online teaching and learning resources, including a teaching guide to the resources, a fully revised testbank, over 250 downloadable figures from the book, and a host of student resources such as multiple-choice questions and over 800 glossary flashcards to help aid revision. Essentials of Anatomy and Physiology for Nursing Practice is essential reading for all nursing students and nursing associate students learning anatomy and physiology for the first time.

This book brings together a cross-fertilization of ideas between human molecular genetics, developmental biology, tissue biology and the biochemistry of cell signalling pathways, in order to create new insights into the mechanisms of normal and abnormal skeletogenesis. This broad perspective is essential in order to understand the aetiology of genetic diseases affecting skeletal development at all levels from genotype to phenotype, i.e. from mutation to syndrome.
The book encompasses normal and abnormal skeletogenesis process by process, beginning with the signalling pathways that control early patterning events, then the molecular control of osteoblast, chondrocyte and osteoclast differentiation, joint formation and finally osteoclast activity. Each step takes into consideration the results of mouse gene cloning and knockout studies, human molecular genetics, and new mouse studies stimulated by the human information. Such an integrated approach is essential if this new understanding is to be applied for future therapeutic strategies.

This book brings together interdisciplinary research in cognitive psychology, cognitive impairment and abnormalities, cognitive networks and neurofeedback, and neurophysiology. Covered are the latest developments, pinpointing directions for future research on cognitive sciences and theory. Essential reading for those working directly in the cognitive sciences or in related specialist areas, Research Trends in Behavior and Executive Function provides an instant overview of current thinking for both experts and newcomers to cognitive sciences.

For 40 years, Bancroft's Theory and Practice of Histological Techniques has established itself as the standard reference for histotechnologists and laboratory scientists, as well as histopathologists. With coverage of the full range of histological techniques used in medical laboratories and pathology departments, it provides a strong foundation in all aspects of histological technology - from basic methods of section preparation and staining, to advanced diagnostic techniques such as immunocytochemistry and molecular testing. This revised and updated 8th Edition by Kim S. Suvarna, Christopher Layton, and John D. Bancroft is a one-stop reference for all those involved with histological preparations and applications, from student to highly advanced laboratory professional. Presents a thorough, up-to-date, and detailed approach to the theory and protocols for preparing cells and tissues for laboratory evaluation, covering topics ranging from basic to advanced Features new content on automation (computer logging and tracking, sub-sampling and archiving of samples), digital scanning techniques for slides used in remote/telepathology, and specialist molecular techniques. Provides superb visual guidance through the use of vivid color illustrations, including additional illustrations of diagnostic modalities and techniques. Contains more summary tables, charts, and boxes throughout for quick reference. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Cajal and De Castro's Neurohistological Methods provides the first English translation of Fernando de Castro's 1933 publication "Elementos de Tecnica Micrografica del Sistema Nervioso ". A student of the famed founder of modern neuroscience, with Santiago Ramon y Cajal also serving as the Editor of the original text, Fernando de Castro recorded all the various protocols that had been used in his laboratory by his students in order to provide a manual of histological procedures specifically designed for the fine structure of the nervous system. This renowned text is virtually unknown in its original form outside the Spanish-speaking world. In a text that reads like a mix between a recipe book and an alchemical manuscript, authors Miguel Merchan, Javier DeFelipe, and Fernando de Castro (descendant of the 1933 publication's author) put the new translation into historical context. This book is also beautifully illustrated with plates of histological techniques, provides a quick guide to new vocabulary, and the author's notes on the translated text. This pivotal work of classic neurohistological techniques is a wonderful addition to the Cajal library.

'An enthralling read' - Dr Rachel Clarke, bestselling author of Dear Life A Royal Society Science Prize shortlisted author 'A remarkable book' - Sunday Times __________ What is phantom limb pain? Can words actually hurt? Why do we experience pain, even after we've healed? We know pain when we feel it. We fear it and try to avoid it. But do we know what it really is? We're currently experiencing a Renaissance in pain science. In recent years our understanding of pain has altered so radically it's fair to say that everything we thought we knew about pain is wrong. As Dr Monty Lyman reveals, we misunderstand pain - with harmful consequences. Exploring cutting-edge research that encompasses everything from phantom aches to persistent pain, as well as interviews with survivors of torture and those who have never felt pain, Dr Lyman not only provides hope for reducing and managing pain but takes us to a deeper understanding of what it means to be human. This is the untold story of pain - our most elusive feeling. 'Accessible and well-written... Dr Lyman takes us into the world of pain' Mail on Sunday __________ Praise for Monty Lyman and The Remarkable Life of the Skin - 'Seriously entertaining' The Times - 'A talented new writer' Sunday Times - 'Beautifully written, revealing and surprising' Daily Mail - 'Imaginatively told' The Spectator - 'An absorbing, fact-packed study' Nature - 'What a read it is' Vogue - 'Fascinating' Daily Express

In the human body, collagen is the most abundant structural protein, forming up to 35% of the entire protein content of the whole body. In this book, the preparation, characterization and applications in tissue regeneration of bovine type 1 collagen are reviewed. Furthermore, collagen is often used in regenerative medicine. In this book, the authors report on the helicity of collagen molecule in fibrils by circular dichroism spectroscopy and the thermograph of fibrils by differential scanning calorimetry (the structural aspects of collagen molecules). In the last chapter, second harmonic generation (SHG) microscopy is reviewed and its potential to visualize collagen fibers in a variety of connective tissues.

Muscle cells, including cardiomyocytes, contain a specialized smooth endoplasmic reticulum (ER), sarcoplasmic reticulum (SR) calcium ions (Ca2+) release and reuptake by the sarcoplasmic reticulum trigger the contraction and relaxation of the myofibrils, respectively. This book examines the control and modulation of the SR and how this may vary among skeletal and cardiac muscle without bypassing the smooth muscle. It presents new and exciting work in this area and identifies promising new research directions. Furthermore, it considers the advances in this relatively unexplored field, offering new insights into the role of SR communication with other organelles and the new concepts about ER stress. Generally, this scientific book brings together contributions from key workersboth in basic and clinical sciences whose studies range from physiological to pathological and molecular to whole animal. In this book, the authors provide insights into the evolution of SR design and function.

For two-semester A&P lab courses. Stunning Visuals and Accessible Tutorials Engage Students in the A&P Lab The Wood, Laboratory Manual for Anatomy & Physiology featuring Martini Art, Sixth Edition is a valuable resource for engaging students in the lab, introducing them to applications, and preparing them for their future careers. The Sixth Edition teaches effective drawing techniques to promote critical thinking and ensure lasting comprehension. This comprehensive lab manual features more than 100 new photos that walk students through core lab processes, lab equipment, and animal organ dissections, as well as art that is adapted from Ric Martini's Fundamentals of Anatomy & Physiology, Tenth Edition. It is available in three formats: Main, Cat, and Pig Versions. The Cat and Pig manuals are identical to the Main Version, with nine additional cat or pig dissection exercises. Note: You are purchasing a standalone product; MasteringA&P does not come packaged with this content. Students, if interested in purchasing this title with MasteringA&P, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information. If you would like to purchase both the physical text and MasteringA&P, search for: 0134137728 / 9780134137728 Laboratory Manual for Anatomy & Physiology featuring Martini Art, Main Version Plus MasteringA&P with eText -- Access Card Package, 6/e Package consists of: 0134130189 / 9780134130187 Laboratory Manual for Anatomy & Physiology featuring Martini Art, Main Version, 6/e 013415732X / 9780134157320 MasteringA&P with Pearson eText -- ValuePack Access Card -- for Laboratory Manual for Anatomy & Physiology, 6/e

The grasp of neuroanatomy, maybe more than in other organ systems, is closely related to function, neurophysiology and neuro-biochemistry. Its understanding requires a working knowledge of the pivotal neuro-embryological events as well as a working knowledge of general anatomy. For these reasons, it remains one of the greatest challenges, both for the aspiring student and for the dedicated mentor in the medical field. The span of books used as references in teaching neuroanatomy is either too detailed or too simplistic in their attempt to balance the time constraints against the key points for each subject. In addition, since the field of neuroscience is currently at the forefront of research, many of the textbooks that are available are written by researchers rather than clinicians, and as a result they tend to suffer a lack of clinical focus. This book, written by a tutor of neuroanatomy and a practising neurosurgeon, attempts to offer a better balance and a more useful formula. This book is composed for the medical student, relying on comments from past medical students. The book begins with an introduction chapter which discusses the organisation of the nervous system, anatomical planes, introduction to neuro-embryology, as well as relevant scalp and skull anatomy. The next succeeding six chapters discuss the central nervous system regionally. Each chapter begins with the key embryological processes that shape the anatomy and function of that region. The gross anatomical description is followed by a short discussion of microscopic anatomy, grey and white matter anatomical features, major connections and key clinical correlations. The next three chapters tackle specific problematic topics separately. The meninges, the cerebrospinal fluid and the lateral ventricles are discussed first, followed by an overview of the cerebral blood supply. A unique chapter focusing on specific skull base complex structures, such as the cavernous sinus region, the sphenoid sinus, and the jugular foramen is subsequently presented. The book ends with two chapters presenting the special sensory senses, vision and audition. These chapters are organised in a system rather than in regional anatomy forms, with an in-depth discussion of related anatomical features.

For courses in one-semester human anatomy. A fresh voice strengthens a visually compelling, classic human anatomy text Revered for its groundbreaking, atlas-style format, detailed illustrations, and exceptionally clear photographs, Human Anatomy has long been known for its quality and sophistication, as well as its scope and level of coverage. Accomplished author and award-winning educator Judi Nath joins the writing team, bringing a fresh voice, enhanced accuracy, and a clear, engaging writing style to the 9th Edition. The new edition builds upon the legacy of previous editions and includes expanded clinical content to help students focus on the types of diseases and injuries they are likely to encounter in their future careers; visually stunning Spotlight Figures in every chapter to guide students through complex topics; and new features that focus students on the key point in each section and use simple analogies and memory devices to help students remember facts and concepts. Also available with Mastering A&P Mastering (TM) A&P is an online homework, tutorial, and assessment program designed to engage students and improve results. Instructors ensure that students arrive ready to learn by assigning educationally effective content before class, and encourage critical thinking and retention with in-class resources such as Learning Catalytics (TM). Students can further master concepts after class through assignments that provide hints and answer-specific feedback. With a wide range of activities available, students can actively learn, understand, and retain even the most difficult concepts. A robust suite of online resources in Mastering A&P, including Spotlight Figure Coaching Activities and Dynamic Study Modules, allow students to interact with content from the book and learn more about the most difficult concepts. For the instructor, the new Ready-to-Go Teaching Modules help them navigate the robust suite of tools available in Mastering A&P to teach the toughest topics. A curated collection of before-class assignments, in-class activities, and after-class assignments are provided to help faculty efficiently plan their lectures and assignments. Instructors can incorporate active learning into their course with the suggested activity ideas and clicker questions or Learning Catalytics (TM) questions. Note: You are purchasing a standalone product; Mastering (TM) A&P does not come packaged with this content. Students, if interested in purchasing this title with Mastering A&P, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information. If you would like to purchase both the physical text and Mastering A&P, search for: 0134296036 / 9780134296036 Human Anatomy Plus Mastering A&P with eText -- Access Card Package Package consists of: 0134292332 / 9780134292335 Mastering A&P with Pearson eText -- ValuePack Access Card -- for Human Anatomy 013432076X / 9780134320762 Human Anatomy Mastering A&P should only be purchased when required by an instructor.

Volume 6 provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. Attention is given to a number of mechanistic advances in the understanding of regulation, particularly the importance of nutrient availability; microRNAs; and cross-talk with other protein degradation pathways. Intracellular pathogen repurposing of autophagy for pathogenic benefit is also provided, with coverage of Herpesvirus protein modulation of autophagy; the varicella-zoster virus and the maintenance of homeostasis; and the relationship between autophagy and the hepatitis b virus. The significance of autophagy in host defense is elucidated, providing a specific focus on facilitation of antigen presentation; participation in thymic development; and the sharing of regulatory nodes with innate immunity. Selective autophagy for the degradation of mitochondria and endocytosed gap junctions are also explored. This book is an asset to newcomers as a concise overview of the regulation of autophagy, its role in host defense and immunity, and selective autophagy, while serving as an excellent reference for more experienced scientists and clinicians looking to update their knowledge. Volumes in the Series Volume 1: Molecular Mechanisms. Elucidates autophagy's association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Volume 2: Role in General Diseases. Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific diseases and developments, including: Crohn's Disease, Gaucher Disease, Huntington's Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis. Volume 4: Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson Disease, cardiac aging, and skeletal muscle atrophy. Volume 5: Role in Human Diseases. Comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy's effects in various cardiovascular, metabolic, and neurodegenerative disorders. Volume 6: Regulation of Autophagy and Selective Autophagy. Provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. Volume 7: Role of Autophagy in Therapeutic Applications. Provides coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality control; the role of autophagy in apoptosis; autophagy in the cardiovascular system; and the relationships between autophagy and lifestyle. Volume 8: Autophagy and Human Diseases. Reviews recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, and introduces new, more effective therapeutic strategies, in the development of targeted drugs and programmed cell death, providing information that will aid on preventing detrimental inflammation. Volume 9: Necrosis and Inflammation in Human Diseases. Emphasizes the role of Autophagy in necrosis and inflammation, explaining in detail the molecular mechanism(s) underlying the formation of autophagosomes, including the progression of Omegasomes to autophagosomes.

Human chorionic gonadotropin (hCG) is produced during pregnancy by the embryo. It promotes progesterone production by corpus luteal cells. It also functions in pregnancy to promote angiogenesis in uterine vasculature, it immuno-blands the invading placental tissue so it is not rejected by the maternal uterine tissues, promotes the growth of the uterus in line with the growth of the fetus, promotes the differentiation of growing cytotrophoblast cells, promotes the quiescence of contractions in the uterine myometrium during the course of pregnancy, and also has function in growth and development of fetal organs. The first edition described the detailed biology, clinical chemistry, and clinical perspectives of hCG and associated molecules, and examines hCG, hyperglycosylated hCG and hCG free ss-subunit, 3 separate and independent molecules with totally sovereign physiological functions. The second edition will include coverage of the many new discoveries that have been made in the last five years: hCG analogues may be the actual driving signal of all human cancers. The editor estimates that 40% of the out of date material will be excluded and replaced with 40% of the exciting new findings. The book will also have a much clearer pregnancy and cancer focus.

The sixth edition of this classic work makes mastering a vast amount of information on internal organs much less daunting. It offers a vivid review of the human body and its structure, and it is an ideal study companion as well as an excellent basic reference text. These are some of the many user-friendly features of this book New color plates on embryology and histology More than 200 outstanding full-color illustrations and 130 clinical correlations Side-by-side images with explanatory text An overview of anatomical terms in each section Emphasizing clinical anatomy, this text integrates current information from a wide range of medical disciplines into discussions of the internal organs, including: Cross-sectional anatomy as a basis for working with modern imaging modalities Detailed explanations of organ topography and function Physiological and biochemical information included where appropriate An entire chapter devoted to pregnancy and human development Volume 2: Internal Organs and its companions Volume 1: Locomotor System and Volume 3: Nervous System and Sensory Organs comprise a must-have resource for students of medicine, dentistry, and all allied health fields.

Ideal as a companion to the text. Perfect as a stand-alone study guide. Body system by system, the exercises and activities you'll find inside will help you to master the basics of anatomy and physiology. Complete the corresponding sections of the Workbook as you proceed from topic to topic in class. See what students are saying online... Cut my study time in half! "This workbook cut my study time in half and helped me to be better prepared for the exam. I was shocked when my score went from 80 to 90 just after one exam!" Great workbook and super easy to understand. "Great workbook and super easy to understand. I love the layout of it and the work in the book follows right along with the book !!! I love it!!" - Brittany S. *Student Workbook answers are available for students in the back of the book

Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and up-to-date, this book offers a valuable guide to these cellular processes whilst inciting researchers to explore their potentially important connections. Volume 5 comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy's effects in various cardiovascular, metabolic, and neurodegenerative disorders. In spite of the increasing importance of autophagy in the various pathophysiological conditions mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases remains poorly understood. This book is an asset to newcomers as a concise overview of the diverse disease implications of autophagy, while serving as an excellent reference for more experienced scientists and clinicians looking to update their knowledge. Volumes in the Series Volume 1: Molecular Mechanisms. Elucidates autophagy's association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Volume 2: Role in General Diseases. Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific diseases and developments, including: Crohn's Disease, Gaucher Disease, Huntington's Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis. Volume 4: Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson Disease, cardiac aging, and skeletal muscle atrophy. Volume 5: Role in Human Diseases. Comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy's effects in various cardiovascular, metabolic, and neurodegenerative disorders. Volume 6: Regulation of Autophagy and Selective Autophagy. Provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. Volume 7: Role of Autophagy in Therapeutic Applications. Provides coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality control; the role of autophagy in apoptosis; autophagy in the cardiovascular system; and the relationships between autophagy and lifestyle. Volume 8: Autophagy and Human Diseases. Reviews recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, and introduces new, more effective therapeutic strategies, in the development of targeted drugs and programmed cell death, providing information that will aid on preventing detrimental inflammation. Volume 9: Necrosis and Inflammation in Human Diseases. Emphasizes the role of Autophagy in necrosis and inflammation, explaining in detail the molecular mechanism(s) underlying the formation of autophagosomes, including the progression of Omegasomes to autophagosomes.

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection and Aging, Volume 4 - Mitophagy presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson's Disease, cardiac aging, and skeletal muscle atrophy. The most current understanding of the proteins and pathways involved in mitophagy are covered, with specific attention to Nix and Bnip3, PINK1/Parkin, Atg32, and FUNDC1. The role of mitophagy in cancer, neurodegeneration, aging, infection, and inflammation is also discussed providing essential insights into the pathogenesis of a variety of mitochondria dysfunction-related diseases. This book is an asset to newcomers as a concise overview of the current knowledge on mitophagy, while serving as an excellent update reference for more experienced scientists working on other aspects of autophagy. From these well-developed foundations, researchers, translational scientists, and practitioners may work to better implement more effective therapies against some of the most devastating human diseases. Volumes in the Series Volume 1: Molecular Mechanisms. Elucidates autophagy's association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Volume 2: Role in General Diseases. Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific diseases and developments, including: Crohn's Disease, Gaucher Disease, Huntington's Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis. Volume 4: Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson Disease, cardiac aging, and skeletal muscle atrophy. Volume 5: Role in Human Diseases. Comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy's effects in various cardiovascular, metabolic, and neurodegenerative disorders. Volume 6: Regulation of Autophagy and Selective Autophagy. Provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. Volume 7: Role of Autophagy in Therapeutic Applications. Provides coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality control; the role of autophagy in apoptosis; autophagy in the cardiovascular system; and the relationships between autophagy and lifestyle. Volume 8: Autophagy and Human Diseases. Reviews recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, and introduces new, more effective therapeutic strategies, in the development of targeted drugs and programmed cell death, providing information that will aid on preventing detrimental inflammation. Volume 9: Necrosis and Inflammation in Human Diseases. Emphasizes the role of Autophagy in necrosis and inflammation, explaining in detail the molecular mechanism(s) underlying the formation of autophagosomes, including the progression of Omegasomes to autophagosomes.

Were you looking for the book with access to MasteringA&P? This product is the book alone, and does NOT come with access to MasteringA&P. Buy Essentials of Human Anatomy and Physiology with MasteringA&P access card 11e (ISBN 9781292057590) if you need access to Mastering as well, and save money on this brilliant resource. A Bestseller Revitalized with a Modern Design and Robust Media Now in its Eleventh Edition, the best-selling Essentials of Human Anatomy and Physiology continues to set the standard for one-semester A&P texts. With her hallmark clear and friendly writing style and meaningful analogies, Elaine Marieb emphasizes the relevance of anatomy & physiology to students' lives and future careers. The book continues to offer just the right balance of anatomy, physiology, and clinical coverage to make the content complete, but not overwhelming. New clinical photos in the Homeostatic Imbalance feature help students visualize diseases and disorders, and new integrated Concept Links help students make connections across topics and body systems. A new, more modern design makes the book more accessible than ever, and new specific references to MasteringA&P direct students to study tools and resources that reinforce their understanding of chapter concepts. Written specifically for the one-semester course, this text presents a superior teaching and learning experience for you and your students. The program allows you to: Bring A&P concepts to life and provide real-world context: A dramatic art and photo program features 3-D anatomy illustrations, process figures with descriptive step text, realistic bone art, illustrated tables, and new clinical photographs in the Homeostatic Imbalance feature. Help students study and retain information: Effective pedagogy, including new Concept Links, Did You Get It? concept check questions, figure questions, and end-of-chapter review questions help students study and retain the information they need. Personalize learning with MasteringA&P (optional purchase): MasteringA&P provides students with engaging experiences that coach them through tough topics in A&P, with tools that help them visualize, practice, and understand A&P. Instructors can easily assign a wide range of question and activity types for automatic grading. New for the Eleventh Edition, learning outcomes and Homeostatic Imbalance features are now numbered for easy assignment in MasteringA&P. Note: You are purchasing a standalone product; MasteringA&P does not come packaged with this content. MasteringA&P is not a self-paced technology and should only be purchased when required by an instructor. MasteringA&P (R) is not included. Students, if MasteringA&P is a recommended/mandatory component of the course, please ask your instructor for the correct ISBN and course ID. MasteringA&P should only be purchased when required by an instructor. Instructors, contact your Pearson representative for more informaiton. MasteringA&P is an online homework, tutorial, and assessment product designed to improve results by helping students quickly master concepts. Students benefit from self-paced tutorials that feature immediate wrong-answer feedback and hints that emulate the office-hour experience to help keep students on track. With a wide range of interactive, engaging, and assignable activities, students are encouraged to actively learn and retain tough course concepts. You can benefit from MasteringA&P at a reduced price by purchasing a pack containing a copy of the book and an access card for MasteringA&P: Essentials of Human Anatomy and Physiology with MasteringA&P access card 11e (ISBN 9781292057590). Alternatively, buy access to MasteringA&P and the eText - an online version of the book - online at www.masteringa&p.com. For educator access, contact your Pearson Account Manager. To find out who your account manager is, visit www.pearsoned.co.uk/replocator

This new volume of "Methods in Enzymology" continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cytoskeletal structure, including such topics as rotational movement of formins studied by fluorescence polarization microscopy, in vitro assembly assays for bacterial actin filaments, and modulators of microtubule plus end growth.
Continues the legacy of this premier serial with quality chapters authored by leaders in the fieldCovers cytoskeletal structureContains chapters with such topics as reconstitution of organelle transport and assaying microtubule nucleation by gamma-tubulin ring complex.

"Clinical Anatomy of the Cranial Nerves" combines anatomical knowledge, pathology, clinical examination, and explanation of clinical findings, drawing together material typically scattered throughout anatomical textbooks. All of the pertinent anatomical topics are conveniently organized to instruct on anatomy, but also on how to examine the functioning of this anatomy in the patient. Providing a clear and succinct presentation of the underlying anatomy, with directly related applications of the anatomy to clinical examination, the book also provides unique images of anatomical structures of plastinated cadaveric dissections. These images are the only ones that exist in this form, and have been professionally produced in the Laboratory of Human Anatomy, University of Glasgow under the auspices of the author. These specimens offer a novel way of visualizing the cranial nerves and related important anatomical structures.
Anatomy of cranial nerves described in text format with accompanying high-resolution images of professional, high-quality prosected cadaveric material, demonstrating exactly what the structures (and related ones) look likeSuccinct yet comprehensive format with quick and easy access to facts in clearly laid out key regions, common throughout the different cranial nervesIncludes clinical examination and related pathologies, featuring diagnostic summaries of potential clinical presentations and clinically relevant questions on the anatomy of these nerves"

Spinnen sind wundervolle Kreaturen. Ihr reichhaltiges und komplexes Verhalten verfA1/4gt A1/4ber hochentwickelte Sinnessysteme und ist hervorragend an die Bedingungen ihrer Umwelt angepasst - wie sich aus ihrem evolutionAren Erfolg ersehen lAsst: sie hatten 400 Millionen Jahre Zeit, ihre Biosensoren zu einer faszinierenden technischen Perfektion und KomplexitAt auszuarbeiten. Professor Friedrich G. Barth stellt in seinem packenden Buch diese "technische Perfektion" in den A1/4bergeordneten Zusammenhang der "Biologie," in der die Passung zwischen Umwelt und Sinnesorganen und die SelektivitAt der Sinne als Bindeglied zwischen Umwelt und Verhalten eine vorranginge Rolle spielt.

The third edition of Physiology and Anatomy for Nurses and Healthcare Practitioners: A homeostatic approach presents homeostasis as a dynamic concept that provides the basis for understanding health and well-being. It recognises how failure to respond to homeostatic disturbances results in imbalances responsible for signs and symptoms of ill-health, and describes how healthcare interventions seek to reverse those imbalances. Accompanied by colour illustrations and a description of related anatomy, the book provides an integrated explanation of body functioning. It discusses the organisation of the human body, main features and processes that must be controlled for health, the organ systems that act as homeostatic regulators, and effectors of homeostatic regulation. It also discusses influences on homeostasis and provides case studies that place examples of ill health and health care into the context of homeostasis. Features of the third edition include: An overview of microbiology and principles of infection management Expanded information on pharmacological principles and actions of the major classes of drugs Expanded discussion on physiological functions in relation to specific pathologies Updates on how the Human Genome project has impacted healthcare Additional case studies to illustrate the healthcare provider's role as an external agent of homeostatic control Photographs of common clinical conditions Access to an accompanying website with supplemental information An essential physiology and anatomy text, this book guides readers through the basic structure and functions of the body systems to more complex issues of clinical disorders and healthcare practice. Coverage includes the cardiovascular, lymphatic, nervous, endocrine, reproductive, and respiratory systems as well as skeletal muscle, embryo development, and circadian rhythms.