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Books > Science & Mathematics > Science: general issues > General
The book is about the post-relativity philosophy of time as
championed by Bertrand Russell and Einstein. It argues that The
Past, Present and Future notion of time is an illusion. The sun, as
daylight, is on constantly with no temporal past and future, except
in chemistry perhaps. Only the earth's revolutions bring temporary
days and nights. So the Bertrand Russell notion that under
relativity man constructs his time is logically unassailable (the
days, weeks, months and years are all human concepts.) Relativity
allows time to begin from anywhere. So the revolutionary view is
that there are or can be as many times as there are frames, or
planets---a world-changing idea but true because it is based on
objective, physical experiments, but generally ignored.
Jean-Henri Fabre was a famous French entomologist whose
observations of insects were praised - this examination of various
beetles is characteristic of his meticulous yet engrossing
descriptions. Fabre's greatest talent was rooted in his genuine
passion for entomology; a natural ability to observe the quirks and
habits of small creatures, and describe them to others in a plain
but lively way. As demonstrated in this book, he wrote about
insects as if they were his friends - seeing their lives play out,
it is thus that qualities of biography are found alongside the
scientific value of this work. In life, Fabre met with backlash for
his unique style - formal schools, whom he in turn criticized for
dryness of tutoring - considered his books long-winded, or even
frivolous. Nevertheless he managed to connect atmospheric pressure
to the behavior of certain insects, while contemporaries such as
Charles Darwin held Fabre in high esteem, to the point of finding
his studies inspirational.
This textbook describes the basics of research in medical,
clinical, and biomedical settings as well as the concepts and
application of epidemiologic designs in research conduct. Design
transcends statistical techniques, and no matter how sophisticated
a statistical modeling, errors of design/sampling cannot be
corrected. The authors of this textbook have presented a complex
field in a very simplified and reader-friendly manner with the
intent that such presentation will facilitate the understanding of
design process and epidemiologic thinking in clinical and
biomedical research. Covers these relevant topics in epidemiology:
Case-Cohort Design Prospective Case-Control Quantitative Evidence
Synthesis (QES) Instant Cohort Design & Case-Crossover Design
Effect Modification & Interaction Epidemiologic Tree -
Molecular Epidemiology & Health Disparities Epidemiologic
Challenge - "Big Data," mHealth, Social Media 3 "Ts" - Team
Science, Transdisciplinary Research, Translational Research Bias,
Random error, Confounding Systems Science & Evidence Discovery
Research is presented as an exercise around measurement, with
measurement error inevitable in its conduct-hence the inherent
uncertainties of all findings in clinical and biomedical research.
Concise Epidemiologic Principles and Concepts covers research
conceptualization, namely research objectives, questions,
hypothesis, design, implementation, data collection, analysis,
results, and interpretation. While the primary focus of
epidemiology is to assess the relationship between exposure (risk
or predisposing factor) and outcome (disease or health-related
event), causal association is presented in a simplified manner,
including the role of quantitative evidence synthesis
(meta-analysis) in causal inference. Epidemiology has evolved over
the past three decades resulting in several fields being developed.
This text presents in brief the perspectives and future of
epidemiology in the era of the molecular basis of medicine. With
molecular epidemiology, we are better equipped with tools to
identify molecular biologic indicators of risk as well as biologic
alterations in the early stages of disease.
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