Most researchers would be amazed to discover that opinions they have about cherished themes in biology and medicine are biased. Van der Steen and Ho contend that logic and methodology are not well applied in biology and medicine, arguing that the impact of social and moral factors on claims within these two disciplines is underestimated. In response to this situation, Van der Steen and Ho present tools from logic and ethics for assessing existing literature. These tools will help to create sound articles and materials in the life sciences.

After reviewing logic and methodological approaches, broad guidelines are used to place science in a social context. Examples from life sciences illustrate the implementation of logic, methodology, and guidelines in forty-five brief case studies. Each study includes comments on quoted and paraphrased passages from a single article or book. Cross-references facilitate the assimilation of lessons from the text. Students, researchers, and scholars in biology, biomedicine, philosophy, and ethics as applied to the life sciences will find this guide useful in improving their research and writing skills.

This book systematically addresses all the major available direct and enabling technologies which have contributed to the revolutionized research and development, thus improvements to existing vaccines. Its target audience is both research and development workers in the field, as well as health-care personnel who use vaccines. It should serve as an invaluable source-book in the vaccine field.

Despite their importance in terms of employment and income generation, inshore fisheries have been a neglected area of study. The review of the common fisheries policy, especially in the light of the need to re-examine the derogation which reserves access to the inshore zone to coastal state vessels, provides an opportunity to redress the balance. With contributions from leading authorities on fisheries management, the book takes an in-depth look at seven European countries, examining the basis for the definition of inshore fisheries, evaluating their status, and describing the salient characteristics of their management. The national studies form the basis for cross-cultural analyses of the social organisation, cultural norms, economic objectives, and institutional structures of inshore fisheries in Europe. Finally, a number of key issues relating to the future of inshore fisheries management in a more integrated approach are examined. Overall the volume reaffirms the invaluable role played by inshore fisheries in the local and regional economies of Europe's complex coastline.

Infrared and Raman Spectroscopy of Biological Materials facilitates a comprehensive and through understanding of the latest developments in vibrational spectroscopy. It contains explains key breakthroughs in the methodologies and techniques for infrared, near-infrared, and Raman spectroscopy. Topics include qualitative and quantitative analysis, biomedical applications, vibrational studies of enzymatic catalysis, and chemometrics.

The current edition of Video Microscopy has been totally revised to reflect the advances in the tools for electronic imaging, processing, recording, and analysis, as well as applications that are being made in video microscopy and related modes of electronic imaging. The less spiral organization of the revised edition reflects an audience expected to be more experi enced in video and computer image processing than in the earlier days when coupling of video equipment and computers to the light microscope was still considered to be a novelty. Nevertheless, we have emphasi2;ed the how-tos, as well as the fundamental principles, involved in imaging and processing ih the light microscope, the human visual system, video and related electronic imaging, and the digital image processor in the hope that the reader will develop enough understanding, not only to apply rationally what is available, but also to contribute actively to the development of this evolving field. In the text, the terms appearing in the Glossary are printed in bold type, generally, at first appearance. Italics are used for emphasis.

Modern computer-intensive statistical methods play a key role in solving many problems across a wide range of scientific disciplines. Like its bestselling predecessors, the fourth edition of Randomization, Bootstrap and Monte Carlo Methods in Biology illustrates a large number of statistical methods with an emphasis on biological applications. The focus is now on the use of randomization, bootstrapping, and Monte Carlo methods in constructing confidence intervals and doing tests of significance. The text provides comprehensive coverage of computer-intensive applications, with data sets available online. Features Presents an overview of computer-intensive statistical methods and applications in biology Covers a wide range of methods including bootstrap, Monte Carlo, ANOVA, regression, and Bayesian methods Makes it easy for biologists, researchers, and students to understand the methods used Provides information about computer programs and packages to implement calculations, particularly using R code Includes a large number of real examples from a range of biological disciplines Written in an accessible style, with minimal coverage of theoretical details, this book provides an excellent introduction to computer-intensive statistical methods for biological researchers. It can be used as a course text for graduate students, as well as a reference for researchers from a range of disciplines. The detailed, worked examples of real applications will enable practitioners to apply the methods to their own biological data.

Series Information:
Studies in Philosophy

A short but engaging exploration of the brain. In Brains, scientist Leif Østergaard explores our most complicated and mysterious organ. From the dissection of Einstein's brain to research on how to map networks of neurons, Østergaard deconstructs the different parts of the brain and provides an engaging overview of its essential functions. He explains how we store information in the synapses of neural networks and how these networks carry commands to our muscles and internal organs and receive sensory input from our skin, eyes, ears, nose, and mouth. Delving into the subconscious, we learn what our brains are doing while we daydream and how neurotransmitters play a role in addiction. In this fascinating book, Østergaard reveals how this enigmatic organ is even more complex than we thought it was. In Reflections, a series copublished with Denmark's Aarhus University Press, scholars deliver 60-page reflections on key concepts. These books present unique insights on a wide range of topics that entertain and enlighten readers with exciting discoveries and new perspectives.

This book presents a general introduction to the measurement of the biological effects of pollution on the marine environment.

Thoroughly revised and updated, including three new chapters on race, sex and human nature Second edition is split into thirteen more manageable chapters (instead of eight long ones in the first edition), matching course syllabi more effectively and making it easier for students and teachers to use the book Covers the essential topics, such as selection, adaptation, modularity, genes and the environment, neuroscience, evolutionary psychology, and free will and determinism Additional textbook features include: chapter summaries, annotated further reading and glossary.

Kweken van bollen in kamer en kas' is the original edition in Dutch of the reference handbook for growing bulbs in a room and greenhouse. Originally published in 1999.

Doubled haploid technology is an important tool for plant breeding. It allows for significant time reduction in the achievement of homozygous breeding lines of value in crop improvement.

This volume provides an excellent overview of haploid induction and the application of doubled haploids. The authors emphasize advances made in the understanding of microspore embryogenesis, but treat also advances in gynogenesis and the manipulation of parthenogenetic haploid development.

The text contains a thorough discussion of the application of haploidy to the improvement of a number of species from various families, including Brassicaceae, Poaceae, and Solanaceae. The various methods applicable to these species are described in detail. Each chapter contains critical evaluation of the scientific literature and an extensive list of references. This volume is ideally suited for plant breeders, geneticists, and plant cell biologists.

The present monograph analyses the FitzHugh-Nagumo (F-N) model Le., the Cauchy problem for some generalized Van der Pol equation depending on three real parameters a, band c. This model, given in (1. 1. 17), governs the initiation of the cardiac impulse. The presence of the three parameters leads to a large variety of dy namics, each of them responsible for a specific functioning of the heart. For physiologists it is highly desirable to have aglobai view of all possible qualitatively distinct responses of the F-N model for all values of the pa rameters. This reduces to the knowledge of the global bifurcation diagram. So far, only a few partial results appeared and they were spread through out the literature. Our work provides a more or less complete theoretical and numerical investigation of the complex phase dynamics and bifurca tions associated with the F-N dynamical system. This study includes the static and dynamic bifurcations generated by the variation of a, band c and the corresponding oscillations, of special interest for applications. It enables one to predict all possible types of initiations of heart beats and the mechanism of transformation of some types of oscillations into others by following the dynamics along transient phase space trajectories. Of course, all these results hold for the F-N model. The global phase space picture enables one to determine the domain of validity of this model."

The main objective of this book is to systematically describe the basic principles of the most widely used techniques for the analysis of physical, structural, and compositional properties of solids with a spatial resolution of approxi mately 1 m or less. Many books and reviews on a wide variety of microanalysis techniques have appeared in recent years, and the purpose of this book is not to replace them. Rather, the motivation for combining the descriptions of various mi croanalysis techniques in one comprehensive volume is the need for a reference source to help identify microanalysis techniques, and their capabilities, for obtaining particular information on solid-state materials. In principle, there are several possible ways to group the various micro analysis techniques. They can be distinguished by the means of excitation, or the emitted species, or whether they are surface or bulk-sensitive techniques, or on the basis of the information obtained. We have chosen to group them according to the means of excitation. Thus, the major parts of the book are: Electron Beam Techniques, Ion Beam Techniques, Photon Beam Techniques, Acoustic Wave Excitation, and Tunneling of Electrons and Scanning Probe Microscopies. We hope that this book will be useful to students (final year undergrad uates and graduates) and researchers, such as physicists, material scientists, electrical engineers, and chemists, working in a wide variety of fields in solid state sciences."

Singularities in Fluids, Plasmas and Optics, which contains the proceedings of a NATO Workshop held in Heraklion, Greece, in July 1992, provides a survey of the state of the art in the analysis and computation of singularities in physical problems drawn from fluid mechanics, plasma physics and nonlinear optics. The singularities include curvature singularities on fluid interfaces, the onset of turbulence in 3-D inviscid flows, focusing singularities for laser beams, and magnetic reconnection. The highlights of the book include the nonlinear Schr dinger equation for describing laser beam focusing, the method of complex variables for the analysis and computation of singularities on fluid interfaces, and studies of singularities for the 3-D Euler equations. The book is suitable for graduate students and researchers in these areas.

Richard Owen (1804-92) was, after Darwin, the most important figure in Victorian natural history. He was, for most of the six decades of his career, Britain's foremost comparative anatomist and vertebrate palaeontologist. Leader of the nineteenth-century museum movement, he founded London's monumental Natural History Museum, wrote and published copiously and won every professional honour. Positioned at the cutting edge of Victorian science, his work attracted enormous general interest, and he himself came to symbolise 'natural history' in the public mind. His company was sought by royalty (Prince Albert), prime ministers (especially Sir Robert Peel), and by contemporary literati such as Charles Dickens. Owen was, however, a controversial figure whose disagreements with colleagues developed into epic power struggles, the most notorious of which were with Darwin and Huxley. As the most renowned opponent of natural selection, Owen was type-cast as a Cuvierian creationist and became the bete noire of the Darwinian evolution debate. In this comprehensive intellectual and scientific biography, Nicolaas Rupke argues that Owen was no simple-minded anti-evolutionist and, moreover, should be freed from the distortion of the evolution dispute that was only a minor part of his work, yet has come to dominate his memory. Using the museum movement as the primary context of explanation, Rupke throws new light on a wide area of Owen's activities. He reveals the central division in Owen's scientific oeuvre between the functionalism of Oxbridge natural theology and the transcendentalism of German nature philosophy. This epistemological duality confused and puzzled his contemporaries as well as laterhistorians. But as Rupke convincingly demonstrates, it was a fundamental extension of the intellectual and political manoeuvering for control of Victorian cultural institutions, and an inextricable part of the rise to public authority of the most articulate proponents of the scientific study of nature.

The intestinal protozoan Giardia was first described over 300 years ago in 1681 by Leeuwenhoek, from his own stools. In his description of Giardia, he noted the size, movement, and morphology of the organism, and associated its presence with the diarrheic nature of his stools and his dietary habits. This truly remarkable account contains the first description of Giardia in morphologic, pathogenic, and epidemiologic terms. Our knowledge of the organisms in the genus Giardia has advanced tremendously in the past two decades. With the advent of new tech nologies, including techniques in electron microscopy, biochemistry, immunochemistry, tissue culture, and physiology, a tidal wave of information has appeared on the organization and function of this parasitic protozoan and its interaction with its host. The purpose of this book is to celebrate the tricentennial discovery of Giardia by Leeuwenhoek by presenting the above-mentioned advances in our knowledge of Giardia and giardiasis. In the first section of this book, the dominant theme is the biology of the organism and the correlation of structure-function relationships."

A new and innovative account of British sociology's intellectual origins that uses previously unknown archival resources to show how the field's forgotten roots in a late nineteenth and early twentieth-century debate about biology can help us understand both its subsequent development and future potential.

Rapid regeneration of city areas has placed the quality of urban design high on public and policy agendas worldwide. This work examines the achievement of quality in the urban environment, in a planning context. Tracing urban design from its roots, the authors draw on both historical and current practices to examine the key physical, political and economic forces at play and the social pressures and impacts brought about by both failures and achievements in urban design. This illustrated critique of towns and cities draws on examples from across Western Europe, South Africa and USA to examine both public and private sector development practices, controls and fiscal policies within a diverse range of localities. The authors indicate the need for a reinstitution of region-provincial approaches, for closer co-ordination bewteen sectors, and revised fiscal policies in planning and development in order to enhance the quality of urban social experience and environments.

This updated book reflects improvements in a variety of techniques used to study the aptamer field. Beginning with a section on selection procedures, the volume continues with methods to characterize aptamers' interaction and structural properties by biophysical approaches, as well as a variety of applications that have been adapted to the aptamer compound class. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Nucleic Acid Aptamers: Selection, Characterization, and Application, Second Edition serves as an ideal guide for researchers aiming to further our understanding of aptamer biology and more.