Kweken van bollen in kamer en kas' is the original edition in Dutch of the reference handbook for growing bulbs in a room and greenhouse. Originally published in 1999.

Doubled haploid technology is an important tool for plant breeding. It allows for significant time reduction in the achievement of homozygous breeding lines of value in crop improvement.

This volume provides an excellent overview of haploid induction and the application of doubled haploids. The authors emphasize advances made in the understanding of microspore embryogenesis, but treat also advances in gynogenesis and the manipulation of parthenogenetic haploid development.

The text contains a thorough discussion of the application of haploidy to the improvement of a number of species from various families, including Brassicaceae, Poaceae, and Solanaceae. The various methods applicable to these species are described in detail. Each chapter contains critical evaluation of the scientific literature and an extensive list of references. This volume is ideally suited for plant breeders, geneticists, and plant cell biologists.

The prevalence of metabolic syndrome (MS) is rising in developing countries and developed countries at such high rates that it is now considered a worldwide public health problem of pandemic proportions. Yet its spread can usually be mitigated by diet and lifestyle behavior. Nutritional Intervention in Metabolic Syndrome brings together coverage of dietary patterns and dietary components to create a complete understanding of the mechanisms by which these diets and components may improve metabolic syndrome. It then presents information on how to treat MS through lifestyle change and nutritional intervention. Witten by experts, the book focuses on diet therapy, nutritional intervention, and oxidative stress in metabolic syndrome. It presents information on dietary patterns in metabolic syndrome, including Mediterranean style diets, DASH, and low calorie diets. The text then provides an understanding of the physiopathology mechanisms in metabolic syndrome and strategies to treat these conditions through nutritional intervention. Chapters cover prevalence of MS, pathophysiology, MS in systemic lupus erythematosus and rheumatoid arthritis, gene-nutrient interactions, MS in adolescents and children, lifestyle change and physical activity, and various effects of dietary components in MS. Research studies examining food groups are important, and there is a trend in the literature to verify the relationship between dietary patterns and cardiovascular risk factors. However, studies examining dietary components, such as olive oil, soy-based products, n-3 polyunsaturated fatty acids, berries, whole grains, nuts, dairy foods, tea, coffee, and alcoholic beverages are also important. The coverage of both in this book gives you an understanding of the pathophysiology underlying MS that you can use to develop strategies to prevent and treat these conditions through nutritional intervention.

A new and innovative account of British sociology's intellectual origins that uses previously unknown archival resources to show how the field's forgotten roots in a late nineteenth and early twentieth-century debate about biology can help us understand both its subsequent development and future potential.

The present monograph analyses the FitzHugh-Nagumo (F-N) model Le., the Cauchy problem for some generalized Van der Pol equation depending on three real parameters a, band c. This model, given in (1. 1. 17), governs the initiation of the cardiac impulse. The presence of the three parameters leads to a large variety of dy namics, each of them responsible for a specific functioning of the heart. For physiologists it is highly desirable to have aglobai view of all possible qualitatively distinct responses of the F-N model for all values of the pa rameters. This reduces to the knowledge of the global bifurcation diagram. So far, only a few partial results appeared and they were spread through out the literature. Our work provides a more or less complete theoretical and numerical investigation of the complex phase dynamics and bifurca tions associated with the F-N dynamical system. This study includes the static and dynamic bifurcations generated by the variation of a, band c and the corresponding oscillations, of special interest for applications. It enables one to predict all possible types of initiations of heart beats and the mechanism of transformation of some types of oscillations into others by following the dynamics along transient phase space trajectories. Of course, all these results hold for the F-N model. The global phase space picture enables one to determine the domain of validity of this model."

Mendelian Randomization: Methods For Causal Inference Using Genetic Variants provides thorough coverage of the methods and practical elements of Mendelian randomization analysis. It brings together diverse aspects of Mendelian randomization from the fields of epidemiology, statistics, genetics, and bioinformatics. Through multiple examples, the first part of the book introduces the reader to the concept of Mendelian randomization, showing how to perform simple Mendelian randomization investigations and interpret the results. The second part of the book addresses specific methodological issues relevant to the practice of Mendelian randomization, including robust methods, weak instruments, multivariable methods, and power calculations. The authors present the theoretical aspects of these issues in an easy-to-understand way by using non-technical language. The last part of the book examines the potential for Mendelian randomization in the future, exploring both methodological and applied developments. Features Offers first-hand, in-depth guidance on Mendelian randomization from leaders in the field Makes the diverse aspects of Mendelian randomization understandable to newcomers Illustrates technical details using data from applied analyses Discusses possible future directions for research involving Mendelian randomization Software code is provided in the relevant chapters and is also available at the supplementary website This book gives epidemiologists, statisticians, geneticists, and bioinformaticians the foundation to understand how to use genetic variants as instrumental variables in observational data. New in Second Edition: The second edition of the book has been substantially re-written to reduce the amount of technical content, and emphasize practical consequences of theoretical issues. Extensive material on the use of two-sample Mendelian randomization and publicly-available summarized data has been added. The book now includes several real-world examples that show how Mendelian randomization can be used to address questions of disease aetiology, target validation, and drug development

Please note this title is suitable for any student studying: Exam Board: OCR Level: A Level Subject: Biology A First teaching: September 2015 First exams: June 2017 Exactly matched to the OCR A Level Biology A specification, the Revision Guide provides comprehensive, specification-linked content, so you can be sure you are covering everything you need to know for the exams. It is packed with engaging revision and practice material to keep you focused and contains a wealth of exam-style questions to test your knowledge and skills to help you fully prepare for the exams.

The main objective of this book is to systematically describe the basic principles of the most widely used techniques for the analysis of physical, structural, and compositional properties of solids with a spatial resolution of approxi mately 1 m or less. Many books and reviews on a wide variety of microanalysis techniques have appeared in recent years, and the purpose of this book is not to replace them. Rather, the motivation for combining the descriptions of various mi croanalysis techniques in one comprehensive volume is the need for a reference source to help identify microanalysis techniques, and their capabilities, for obtaining particular information on solid-state materials. In principle, there are several possible ways to group the various micro analysis techniques. They can be distinguished by the means of excitation, or the emitted species, or whether they are surface or bulk-sensitive techniques, or on the basis of the information obtained. We have chosen to group them according to the means of excitation. Thus, the major parts of the book are: Electron Beam Techniques, Ion Beam Techniques, Photon Beam Techniques, Acoustic Wave Excitation, and Tunneling of Electrons and Scanning Probe Microscopies. We hope that this book will be useful to students (final year undergrad uates and graduates) and researchers, such as physicists, material scientists, electrical engineers, and chemists, working in a wide variety of fields in solid state sciences."

This book had its genesis in Dr. Davis' remarkable editorial in the "New England Journal of Medicine" that sharply criticized medical schools for lowering their standards of admission to fill minority quotas and ultimately risking the lives of patients. Davis' position (widely held, but seldom articulated) is that the standard of medical care is an even higher ideal than the redress of past racial injustice. A passionate battle is now being fought in our universities over the freedom to pursue ideals of objectivity and intellectual freedom that are incompatible with the mandates of a pragmatic social policy."Storm Over Biology" examines many of the areas where scientific and social interests intersect and often conflict, such as genetic engineering and sociobiology. The essays are grouped under six headings: genetics, racism and affirmative action; objectivity and science; evolution - sociobiology, ethics, and molecular genetics; medical education and affirmative action; public concern over science; and genetic engineering.

Singularities in Fluids, Plasmas and Optics, which contains the proceedings of a NATO Workshop held in Heraklion, Greece, in July 1992, provides a survey of the state of the art in the analysis and computation of singularities in physical problems drawn from fluid mechanics, plasma physics and nonlinear optics. The singularities include curvature singularities on fluid interfaces, the onset of turbulence in 3-D inviscid flows, focusing singularities for laser beams, and magnetic reconnection. The highlights of the book include the nonlinear Schr dinger equation for describing laser beam focusing, the method of complex variables for the analysis and computation of singularities on fluid interfaces, and studies of singularities for the 3-D Euler equations. The book is suitable for graduate students and researchers in these areas.

As one of the most quantitative of ecological subdisciplines, resource competition is an important, central area of ecology. Recently research into this area has increased dramatically and resource competition models have become more complex. The characterisation of this phenomenon is therefore the aim of this book. Resource Competition seeks to identify the unifying principles emerging from experimental and theoretical approaches as well as the differences between organisms, illustrating that greater knowledge of resource competition will benefit human and environmental welfare. This book will serve as an indispensable guide to ecologists, evolutionary biologists and environmental managers, and all those interested in resource competition as an emerging discipline.

The intestinal protozoan Giardia was first described over 300 years ago in 1681 by Leeuwenhoek, from his own stools. In his description of Giardia, he noted the size, movement, and morphology of the organism, and associated its presence with the diarrheic nature of his stools and his dietary habits. This truly remarkable account contains the first description of Giardia in morphologic, pathogenic, and epidemiologic terms. Our knowledge of the organisms in the genus Giardia has advanced tremendously in the past two decades. With the advent of new tech nologies, including techniques in electron microscopy, biochemistry, immunochemistry, tissue culture, and physiology, a tidal wave of information has appeared on the organization and function of this parasitic protozoan and its interaction with its host. The purpose of this book is to celebrate the tricentennial discovery of Giardia by Leeuwenhoek by presenting the above-mentioned advances in our knowledge of Giardia and giardiasis. In the first section of this book, the dominant theme is the biology of the organism and the correlation of structure-function relationships."

Richard Owen (1804-92) was, after Darwin, the most important figure in Victorian natural history. He was, for most of the six decades of his career, Britain's foremost comparative anatomist and vertebrate palaeontologist. Leader of the nineteenth-century museum movement, he founded London's monumental Natural History Museum, wrote and published copiously and won every professional honour. Positioned at the cutting edge of Victorian science, his work attracted enormous general interest, and he himself came to symbolise 'natural history' in the public mind. His company was sought by royalty (Prince Albert), prime ministers (especially Sir Robert Peel), and by contemporary literati such as Charles Dickens. Owen was, however, a controversial figure whose disagreements with colleagues developed into epic power struggles, the most notorious of which were with Darwin and Huxley. As the most renowned opponent of natural selection, Owen was type-cast as a Cuvierian creationist and became the bete noire of the Darwinian evolution debate. In this comprehensive intellectual and scientific biography, Nicolaas Rupke argues that Owen was no simple-minded anti-evolutionist and, moreover, should be freed from the distortion of the evolution dispute that was only a minor part of his work, yet has come to dominate his memory. Using the museum movement as the primary context of explanation, Rupke throws new light on a wide area of Owen's activities. He reveals the central division in Owen's scientific oeuvre between the functionalism of Oxbridge natural theology and the transcendentalism of German nature philosophy. This epistemological duality confused and puzzled his contemporaries as well as laterhistorians. But as Rupke convincingly demonstrates, it was a fundamental extension of the intellectual and political manoeuvering for control of Victorian cultural institutions, and an inextricable part of the rise to public authority of the most articulate proponents of the scientific study of nature.

This book gives a comprehensive overview of recent advancements in both theory and practical implementation of plasmonic probes. Encompassing multiple disciplines, the field of plasmonics provides a versatile and flexible platform for nanoscale sensing and imaging. Despite being a relatively young field, plasmonic probes have come a long way, with applications in chemical, biological, civil, and architectural fields as well as enabling many analytical schemes such as immunoassay, biomarkers, environmental indexing, and water quality sensing, to name but a few. The objective of the book is to present in-depth analysis of the theory and applications of novel probes based on plasmonics, with a broad selection of specially-invited chapters on the development, fabrication, functionalization, and implementation of plasmonic probes as well as their integration with current technologies and future outlook. This book is designed to cater to the needs of novice, seasoned researchers and practitioners in academia and industry, as well as medical and environmental fields.

Rapid regeneration of city areas has placed the quality of urban design high on public and policy agendas worldwide. This work examines the achievement of quality in the urban environment, in a planning context. Tracing urban design from its roots, the authors draw on both historical and current practices to examine the key physical, political and economic forces at play and the social pressures and impacts brought about by both failures and achievements in urban design. This illustrated critique of towns and cities draws on examples from across Western Europe, South Africa and USA to examine both public and private sector development practices, controls and fiscal policies within a diverse range of localities. The authors indicate the need for a reinstitution of region-provincial approaches, for closer co-ordination bewteen sectors, and revised fiscal policies in planning and development in order to enhance the quality of urban social experience and environments.

Knowledge of the three-dimensional structure of a protein is absolutely required for the complete understanding of its function. The spatial orientation of amino acids in the active site of an enzyme demonstrates how substrate specificity is defined, and assists the medicinal chemist in the design of s- cific, tight-binding inhibitors. The shape and contour of a protein surface hints at its interaction with other proteins and with its environment. Structural ana- sis of multiprotein complexes helps to define the role and interaction of each individual component, and can predict the consequences of protein mutation or conditions that promote dissociation and rearrangement of the complex. Determining the three-dimensional structure of a protein requires milligram quantities of pure material. Such quantities are required to refine crystallization conditions for X-ray analysis, or to overcome the sensitivity limitations of NMR spectroscopy. Historically, structural determination of proteins was limited to those expressed naturally in large amounts, or derived from a tissue or cell source inexpensive enough to warrant the use of large quantities of cells. H- ever, with the advent of the techniques of modern gene expression, many p- teins that are constitutively expressed in minute amounts can become accessible to large-scale purification and structural analysis.

Carefully delineating each step in the formation of the lung, Lung Growth and Development examines prenatal and postnatal lung development...the regulation of surfactant protein gene expression and models for the analysis of epithelial gene transcription and function...cellular differentiation and the role of mesenchymal cells...airway gland growth and differentiation...growth regulation in the tracheobronchial epithelium and mucociliary differentiation...embryonic precursors of the pulmonary nervous system and the development of lung innervation...Clara cells, airway smooth muscle development, cell interactions in vessel formation, and the surfactant system...respiratory distress syndrome, bronchopulmonary dysplasia, and compensatory lung growth...and more. Written by over 30 international experts, Lung Growth and Development is a practical guide for pulmonologists and pulmonary disease specialists, physiologists, molecular and cellular biologists, pathologists, neonatalogists and pediatricians, anatomists, pathologists, and graduate-level and medical school students in these disciplines.

Training a powerful lens on the microscopic wonders of the universe, hundreds of photos, both exquisite and strange, accompany this startling expose of a secret world invisibly evolving around us for billions of years. Silver Winner of the 2021 IBPA Benjamin Franklin Award for Nature & Environment Microfossils-the most abundant, ancient, and easily accessible of Earth's fossils-are also the most important. Their ubiquity is such that every person on the planet touches or uses them every single day, and yet few of us even realize they exist. Despite being the sole witnesses of 3 billion years of evolutionary history, these diminutive fungi, plants, and animals are themselves invisible to the eye. In this microscopic bestiary, prominent geologist, paleontologist, and scholar Patrick De Wever lifts the veil on their mysterious world. Marvelous Microfossils lays out the basics of what microfossils are before moving on to the history, tools, and methods of investigating them. The author describes the applications of their study, both practical and sublime. Microfossils, he explains, are indispensable in age-dating and paleoenvironmental reconstruction, which guide enormous investments in the oil, gas, and mining industries. De Wever shares surprising stories of how microfossils made the Chunnel possible and have unmasked perpetrators in jewel heists and murder investigations. He also reveals that microfossils created the stunning white cliffs on the north coast of France, graced the tables of the Medici family, and represent our best hope for discovering life on the exoplanets at the outer edges of our solar system. Describing the many strange and beautiful groups of known microfossils in detail, De Wever combines lyrical prose with hundreds of arresting color images, from delicate nineteenth-century drawings of phytoplankton drafted by Ernst Haeckel, the "father of ecology," to cutting-edge scanning electron microscope photographs of billion-year-old acritarchs. De Wever's ode to the invisible world around us allows readers to peer directly into a minute microcosm with massive implications, even traversing eons to show us how life arose on Earth.

Practical Analysis and Reconstruction of Shooting Incidents, Second Edition presents a holistic approach to shooting incident analysis and reconstruction, covering the entire spectrum of related sub-disciplines of forensic science. The book reviews basic firearm design and function, ammunition components, and terminology, explaining what constitutes pertinent evidence and appropriate results relative to autopsies, forensic laboratory analysis, and reenactments. The second edition features numerous additions including: Four new chapters Complete and extensive updates to all 16 original chapters Three case studies contributed by renowned professionals in the field New and revised exercises at the ends of chapters, with answers provided An expanded glossary of terminology Nearly 340 figures and illustrations, with several in full color New and updated references and suggested readings Appendices containing relevant terminology, checklists, and other resources The book details the mathematics of shooting reconstruction in clear, precise language that allows readers-both those with and without extensive science backgrounds-to apply a logical thought process to the evaluation of shooting scene evidence in order to establish the probable related events to the shooting incident. This new edition provides up-to-date information for field investigators to recognize, preserve, document, and interpret the physical evidence typically found after shooting incidents. In addition to the hundreds of illustrations, the book uses both case studies and step-by-step outlines to clearly describe the required analytical processes involved in reconstructing and interpreting shooting incident scenes.

A myriad of different scenarios await those entering the field of forensic pathology, ranging from gunshot wounds to asphyxiation to explosives to death from addiction. Essential Forensic Pathology: Core Studies and Exercises helps prepare pathologists in training by establishing what they must know about the most common death scenes they will encounter. The book begins by discussing the coaching objectives in medical education and follows with a description of the 15 different rotations of the forensic pathology resident. Using a consistent and concise format, the book describes the facility where the rotation takes place, the necessary skills, the laboratory equipment, and other components of the rotation. The main portion of the book presents forensic pathology essentials in the form of learning objectives-each delineated with a code: "M" for items students must know, and "S" for those they must do. This section begins by discussing the government's role, describes medical examiner and coroner systems, and analyzes the academic discipline of forensic pathology. Next, the book focuses on hands-on elements of forensic pathology, with chapters on scene investigation, identification, and postmortem changes (signs of death). Objectives are also presented for various causes of death, including gunshot wounds, stab wounds, asphyxiation, sex-related death, and death from addiction. Additional chapters cover bombs and explosive devices, mental disease, epidemics, and issues related to forensic entomology. Each chapter contains a list of pertinent vocabulary and references for further study. By mastering the objectives contained in each chapter of this manual, forensic pathology students will be ready to pass certification exams and work confidently in the field.