Biology is the natural science that studies life on our planet: from fungi to fossils and ecosystems to extremophiles, there is a whole world waiting to be discovered.Mind Maps: Biology helps you to understand the natural world and to learn its language by exploring ten mind maps, which are powerful tools for visual learning and understanding. Complex ideas are explained using text and illustrations that are easy to follow. Featuring specially commissioned, hand-drawn maps, diagrams and doodles, together with an expert analysis of concepts, this book provides a wealth of visual information across a range of complex subjects.

"Understanding Biostatistics" looks at the fundamentals of biostatistics, using elementary statistics to explore the nature of statistical tests.

This book is intended to complement first-year statistics and biostatistics textbooks. The main focus here is on ideas, rather than on methodological details. Basic concepts are illustrated with representations from history, followed by technical discussions on what different statistical methods really mean. Graphics are used extensively throughout the book in order to introduce mathematical formulae in an accessible way.

Key features: Discusses confidence intervals and p-values in terms of confidence functions. Explains basic statistical methodology represented in terms of graphics rather than mathematical formulae, whilst highlighting the mathematical basis of biostatistics. Looks at problems of estimating parameters in statistical models and looks at the similarities between different models. Provides an extensive discussion on the position of statistics within the medical scientific process. Discusses distribution functions, including the Guassian distribution and its importance in biostatistics.

This book will be useful for biostatisticians with little mathematical background as well as those who want to understand the connections in biostatistics and mathematical issues.

Originally published in 1979. This reprints the revised and expanded edition of 1996. In this volume, physicists, biologists and chemists, who have been involved in some of the most exciting discoveries in modern scientific thought explore issues which have shaped modern physics and which hint at what may form the next scientific revolution. The major issues discussed are the understanding of time and space, quantum and relativity theories and recent attempts to unite them and related questions in theoretical biology.

This book was originally published in 1971. Discoveries in modern biology can radically change human life as we know it. As our understanding of living processes, such as inheritance, grows, so do the possibilities of applying these results for good and evil, such as the treatment of disease, the control of ageing, behaviour and genetic engineering. These discoveries and their implications are discussed by some of the world's leading biologists

Examines harmonization of the US Federal Food, Drug, and Cosmetic Act with international regulations as they apply to human drug and device development, research, manufacturing, and marketing. The Second Edition focuses on the new drug approval process, cGMPs, GCPs, quality system compliance, and corresponding documentation requirements. Written in a jargon-free style, it draws information from a wide range of resources. It demystifies the inner workings of the FDA and facilitates an understanding of how it operates with respect to compliance and product approval. FDA Regulatory Affairs: provides a blueprint to the FDA and drug, biologic, and medical device development offers current, real-time information in a simple and concise format contains a chapter highlighting the new drug application (NDA) process discusses FDA inspection processes and enforcement options includes contributions from experts at companies such as Millennium and Genzyme, leading CRO's such as PAREXEL and the Biologics Consulting Group, and the FDA Three all-new chapters cover: clinical trial exemptions advisory committees provisions for fast track

The book presents topics in discrete biomathematics. Mathematics has been widely used in modeling biological phenomena. However, the molecular and discrete nature of basic life processes suggests that their logic follow principles that are intrinsically based on discrete and informational mechanisms. The ultimate reason of polymers, as key element of life, is directly based on the computational power of strings, and the intrinsic necessity of metabolism is related to the mathematical notion of multiset. The switch of the two roots of bioinformatics suggests a change of perspective. In bioinformatics, the biologists ask computer scientists to assist them in processing biological data. Conversely, in infobiotics mathematicians and computer scientists investigate principles and theories yielding new interpretation keys of biological phenomena. Life is too important to be investigated by biologists alone, and though computers are essential to process data from biological laboratories, many fundamental questions about life can be appropriately answered by a perspicacious intervention of mathematicians, computer scientists, and physicists, who will complement the work of chemists, biochemists, biologists, and medical investigators. The volume is organized in seven chapters. The first part is devoted to research topics (Discrete information and life, Strings and genomes, Algorithms and Biorhythms, Life Strategies), the second one to mathematical backgrounds (Numbers and Measures, Languages and Grammars, Combinations and Chances).

Systems biology is the study of organisms as interacting networks of genes, proteins and reactions. Practical Systems Biology provides a detailed overview of the different approaches used in this relatively new discipline, integrating bioinformatics, genomics, proteomics and metabolomics. Various areas of research are also discussed, including the use of computational models of biological processes, and post-genomic research. Each chapter is written by an experienced researcher and gives an excellent account of various issues of systems biology that is suitable for postgraduate and postdoctoral researchers who are interested in this expanding area of science.

Visualization technology is becoming increasingly important for medical and biomedical data processing and analysis. The interaction between visualization and medicine is one of the fastest expanding fields, both scientifically and commercially. This book discusses some of the latest visualization techniques and systems for effective analysis of such diverse, large, complex, and multi-source data.

Matters of Sport is a tribute to Eric Dunning, the leading sports sociologist in the English-speaking world. This book addresses Dunning's contributions to the sociological and historical study of sport, covering key topics such as hooliganism, celebrity and gender relations.

A broad range of leading academics from Europe and North America reflect on the ways in which Dunning's work has influenced their own research and understanding of sport.

This volume was previously published as a special issue of the journal Sport in Society.

The role of competition within communities, in shaping the structure and composition of the community matrix itself and in influencing day to day functioning of the system is particularly controversial. This book offers a synthesis of these arguments and provides an overview of existing knowledge about competition and organizing that knowledge in such a way that new research paths are suggested. The author presents an original and at times controversial view of competition and its role in ecological communities, not only summarizing what is known but stressing the unknowns, describing unresolved problems and suggesting avenues for further research.

This book examines information processing performed by bio-systems at all scales: from genomes, cells and proteins to cognitive and even social systems. It introduces a theoretical/conceptual principle based on quantum information and non-Kolmogorov probability theory to explain information processing phenomena in biology as a whole. The book begins with an introduction followed by two chapters devoted to fundamentals, one covering classical and quantum probability, which also contains a brief introduction to quantum formalism, and another on an information approach to molecular biology, genetics and epigenetics. It then goes on to examine adaptive dynamics, including applications to biology, and non-Kolmogorov probability theory. Next, the book discusses the possibility to apply the quantum formalism to model biological evolution, especially at the cellular level: genetic and epigenetic evolutions. It also presents a model of the epigenetic cellular evolution based on the mathematical formalism of open quantum systems. The last two chapters of the book explore foundational problems of quantum mechanics and demonstrate the power of usage of positive operator valued measures (POVMs) in biological science. This book will appeal to a diverse group of readers including experts in biology, cognitive science, decision making, sociology, psychology, and physics; mathematicians working on problems of quantum probability and information and researchers in quantum foundations.

Who owns your sex organs? Different cultures today and in different epochs have given a variety of answers to this question. It may seem self evident that every individual owns and has sovereignty over his or her own body parts, such as the head, legs, nose, stomach, pancreas, and other body parts. The sex organs, however, seem to be an exception. Even though they are as much an integral part of the individual as a leg or a liver, the sex organs are unique in that many cultures have established laws and taboos over the use and even the mere display of the sex organs. Thus, certain cultures have placed constraints over the individual's ownership of his or her sex organs and actively regulate and restrict the individual's access and use of those organs. In other cultures, the question of ownership of the sex organs is more decisively answered. In any culture where circumcision to any degree of either the male or female is practiced, permitted, encouraged, or even merely tolerated, it is clear that the individual is not considered to own his own sex organs. In the United States today, the medical establishment has created an is considered acceptable and desirable that anyone for environment where it any reason can authorize or execute the amputation of the foreskin from a male child's penis."

Many athletes suffer health and sports consequences related to inadequate nutrition to meet their sports demands. It often goes unrecognized and untreated if they do not have the stereotypical diagnosis of an “eating disorder.” Highly marketable for those looking to gain an extra edge above the competition by maximizing their health through appropriate nutrition and mental work. The book has background information on the problem and serves as an instruction manual for coaches and parents. Female athletes’ personal narratives are dispersed within the information.

Insights and analysis that challenge current thought on consumer branding theory and strategy Pharmaceutical companies need to go beyond simply relying on strong sales forces and innovative research and development to succeed. Effective branding strategy is essential. PharmaceuticalsWhere's the Brand Logic?: Branding Lessons and Strategy discusses in detail the application of current consumer branding theory to pharmaceutical marketing. This comprehensive book pulls information from fast moving consumer goods (FMCG) research and brand theory and applies it to the pharmaceutical world. It looks at branding on multiple levels within the pharmaceutical industry, including the industry brand, the corporate brand, the franchise brand, and the global and local product brand. Practical strategies are extensively explained and future challenges facing the pharmaceutical industry are explored, all geared to help any pharmaceutical professional to successfully market his or her brand. PharmaceuticalsWhere's the Brand Logic?: Branding Lessons and Strategy may well become a daily reference for anyone in the industry, providing in a single volume a framework for the organization of a brand portfolio for any pharmaceutical company. This unique resource challenges traditional thought about the concept of branding in the pharmaceutical industry, examining several of the most difficult branding theory issues. This helpful guide provides several figures to fully explain data. Topics in PharmaceuticalsWhere's the Brand Logic?: Branding Lessons and Strategy include: what is branding how is branding applied to the FMCG and pharmaceutical industries corporate brandsand how they can be leveraged franchise branding as a business strategy developing and sustaining pharmaceutical brands over time saving the credibility of the pharmaceutical industry changing the pharmaceutical business model to use branding as a strategic tool much, much more PharmaceuticalsWhere's the Brand Logic?: Branding Lessons and Strategy provides the information and tools to help gain the competitive edge in a tough marketplace. This is an invaluable resource for anyone in the global pharmaceutical industry, including marketing personnel, senior management, general managers, strategy groups, and training departments.

Invasive species have come to dominate 3% of the Earth 's ice-free surface, constituting one of the most serious ecological and economic threats of the new millennium, and freshwater systems are particularly vulnerable. This book examines the identity, distribution, and impact of freshwater non-indigenous species and the dynamics of their invasion. It focuses on old and new invaders and provides a starting point for further research.

Coral reefs have shaped the surface of our planet far more than has any other ecosystem. They are dynamic systems, producing limestone at the rate of 400-2,000 tons per hectare per year, and influencing the chemical balance of the world's oceans. Coral reefs have been around since before the prairies or other ecosystems of flowering plants existed, yet they vanish about a million years before other groups of organisms each time there is a global mass extinction. They return after each catastrophe, however, following a long period of absence. Although coral reefs are the most productive communities in the sea, the fisheries of coral reefs are among the most vulnerable to overexploitation. Despite having the power to create the most massive structures in the world made by living creatures (including man), the thin veneer of living tissue of coral reef is particularly sensitive to natural disturbances and effects of human activities. Coral reefs are the first to go during periods of climate change, but they have always come back. This combination of attributes, creative power and fragility, resilience and sensitivity, makes management of coral-reef systems a challenge to science. Over 70% of the coral reefs in the Caribbean and Asian waters have been degraded, and perhaps a third of the 400 species of corals in Japanese waters are in danger of local extinction unless effective coastal management practices are established. This book presents what is known about factors that shift the balance between accretion and erosion, recruitment and mortality, stony corals and filamentous algae, recovery and degradation--the life and death of coral reefs. Insight into the factors controlling thedirection of these processes is essential for appropriate management decisions.

What is intrinsic value? What is the origin of value? Are people always superior to nature? This book is a philosophical analysis of the human relationship to the non-human world. It is a pioneering study of the philosophy of nature-conservation in relation to the discussion of intrinsic value. Vilkka develops a naturalistic or naturocentric theory of value that is based on ethical extensionism and pluralism. Vilkka analyzes natural values and environmental attitudes: zoocentrism, biocentrism, and ecocentrism. This book forms a taxonomy for nature having intrinsic value. The theory of intrinsic value is based on naturocentric and naturogenic values. The book questions the thesis of weak anthropocentrism that denies the existence of naturogenic values. In Vilkka's theory, animals and nature are the origin of value. She defends the existence of zoogenic and biogenic values in the non-human world and discusses the possibility of ecogenic value, nature as a whole having value independent of human or animal minds. Vilkka analyzes the goodness and rights of nature, the problem of priorities, and ecological humanism. A naturocentric recommendation is that the well-being of animals and nature should have priority over human values at least in some real decision contexts. Ecological humanism recommends an attitude of respect for people, animals, and nature. The book includes an extensive glossary, index, and bibliography.

This set comprises 40 volumes covering nineteenth and twentieth century European and American authors. Available as a complete set, mini boxed sets (by theme) or as individual volumes.

Living Marine Resources provides a thorough, up-to-date introduction to all aspects of fisheries science. This clearly written text offers insight into a topic of increasing importance--the wise utilization and management of sea fisheries to maximize production without exceeding their carrying capacity. Adoption of the approaches presented will improve the conservation and management of the many world fisheries that are suffering from years of inefficient practices. The book is divided into five sections, beginning with an introduction to the ocean environment and the various resource species. Part two examines fisheries biology, including age, growth, fecundity, and mortality, enabling readers to appreciate yield models designed to give estimates of maximum sustainable yield and maximum economic yield. The third part covers gear, methods, and landings and includes material on the handling and processing of seafood as well as aquaculture. In part four, yield models are presented to introduce students to theories on population dynamics, stock assessment, and management. The book concludes with coverage of recreational fisheries, including socioeconomic importance, catch and effort research, management techniques, and their interface with commercial fisheries. Living Marine Resources is an invaluable introduction to the subject for advanced undergraduate and graduate students of fisheries science. In addition, the material presented will be valuable to fishery and social scientists, fishery officers and administrators, and students in biology, engineering, economics, and law.

The future of the human posture is in the spotlight. The 200-year-old locomotion paradigm can no longer resist the advancement of knowledge, yet 2,500 years of thinking on the place of verticalized human anatomy and its reflexive consciousness in the natural history of life and the Earth, is more relevant than ever. This book retraces these reflections from pre-Socratic philosophers, focusing on the link between verticality and the most complex and consciously reflexive nervous system on the top rung of the ladder of living beings. The origin of animated forms, or animals, was considered metaphysical until the 19th century but reflection on their inception, from fertilization, paved the way for mathematics of infinitesimal geometry and dynamics. The simian filiation was inconceivable until Jean-Baptiste de Lamarck bridged the gap in 1802 with the locomotion postulate to explain the transition from quadrupedal to bipedal posture, sustained by the hypothesis of inheritance of acquired characteristics. This doctrine was overturned in 1987 by the discovery of the embryonic origins of the straightening - specific dynamics linked to neurogenesis - confirming the natural place of human verticality and nervous system complexity with its psychomotor and cognitive consequences. Sapiens find themselves at the physical limit of the straightening while mechanisms of gametogenesis have never ceased in making neurogenesis exponentially more complex. Is the future exclusively terrestrial or does intrauterine hominization open up new perspectives for space exploration? Posturologists, occlusodontics, osteopaths, cognisciences - all anthropological sciences exposed to human verticality are concerned with this discovery, which allows Sapiens to face their natural destiny

The effects of isolation, area size, and habitat quality on the survival of animal and plant populations in the cultural landscape are central aspects of a research project started in Germany in 1993 (, Forschungsverbund, Isolation, FHichengroBe und BiotopquaIiHit', abbreviated to 'FIFB'). After a long period of preparation, scientists from seven univer sities and one research institution started to work within the frame of this project. Fund ing for four years was provided by the former German Federal Ministry of Research and Technology (BMFT), now the Ministry of Education and Research (BMBF). A strong focus of the project has been the improvement of the methodology for environmental impact assessments and the implementation of results into environmental planning. As there is a certain risk that national projects develop some kind of 'mental in breeding', it was decided to discuss concepts, methods, and first results with scientists of international reputation at a rather early stage of the project. For this purpose, an inter national workshop was held in the small village of Lubast, north of Leipzig (state of Saxony) in March 1995. 130 scientists from 10 nations met to discuss and debate issues surrounding habitat fragmentation for three days. Papers presented there formed the basis for this book. As discussions included general reviews as well as particular case studies, we decided to structure this book in a similar way. Consequently, a combination of broad and more general, review-like papers as well as original papers are presented."

Makes connections between diseases, drugs and signaling in those chapters not specifically devoted to pathogens.

Reviews background in first 5 chapters then offers chapters on cancers and apoptosis and on bacteria and viruses.

Signaling in the immune, endocrine (hormonal) and nervous systems covered along with cancer, apoptosis and gene regulation.

Each chapter ends with a problem section to facilitate discussion.