This is the second volume of Advances in Acoustic Microscopy. It continues the aim of presenting applications and developments of techniques that are related to high-resolution acoustic imaging. We are very grateful to the authors who have devoted considerable time to preparing these chapters, each of which describes a field of growing importance. Laboratories that have high-performance acoustic microscopes are frequently asked to examine samples for which the highest available resolution is not necessary, and the ability to penetrate opaque layers is more significant. Such applications can be thought of as bridging the gap be tween acoustic microscopy at low gigahertz frequencies, and on the one hand nondestructive testing of materials at low megahertz frequencies and on the other hand medical ultrasonic imaging at low megahertz frequencies. Commercial acoustic microscopes are becoming increasingly available and popular for such applications. We are therefore delighted to be able to begin the volume with chapters from each of those two fields. The first chapter, by Gabriele Pfannschmidt, describes uses of acoustic microscopy in the semiconductor industry. It provides a splendid balance to the opening chapter of Volume 1, which came from a national research center, being written from within a major European electronics industry itself. Dr Pfann schmidt describes the use of two quite different types of acoustic microscopes, and points out the advantages of each for specific purposes.

Systems biology is the study of organisms as interacting networks of genes, proteins and reactions. Practical Systems Biology provides a detailed overview of the different approaches used in this relatively new discipline, integrating bioinformatics, genomics, proteomics and metabolomics. Various areas of research are also discussed, including the use of computational models of biological processes, and post-genomic research. Each chapter is written by an experienced researcher and gives an excellent account of various issues of systems biology that is suitable for postgraduate and postdoctoral researchers who are interested in this expanding area of science.

This book offers a comprehensive account of vitalism and the Romantic philosophy of nature. The author explores the rise of biology as a unified science in Germany by reconstructing the history of the notion of "vital force," starting from the mid-eighteenth through the early nineteenth century. Further, he argues that Romantic Naturphilosophie played a crucial role in the rise of biology in Germany, especially thanks to its treatment of teleology. In fact, both post-Kantian philosophers and naturalists were guided by teleological principles in defining the object of biological research. The book begins by considering the problem of generation, focusing on the debate over the notion of "formative force." Readers are invited to engage with the epistemological status of this formative force, i.e. the question of the principle behind organization. The second chapter provides a reconstruction of the physiology of vital forces as it was elaborated in the mid- to late-eighteenth century by the group of physicians and naturalists known as the "Goettingen School." Readers are shown how these authors developed an understanding of the animal kingdom as a graded series of organisms with increasing functional complexity. Chapter three tracks the development of such framework in Romantic Naturphilosophie. The author introduces the reader to the problem of classification, showing how Romantic philosophers of nature regarded classification as articulated by a unified plan that connects all living forms with one another, relying on the idea of living nature as a universal organism. In the closing chapter, this analysis shows how the three instances of pre-biological discourse on living beings - theory of generation, physiology and natural history - converged to form the consolidated disciplinary matrix of a general biology. The book offers an insightful read for all scholars interested in classical German philosophy, especially those researching the philosophy of nature, as well as the history and philosophy of biology.

In the past fifteen years there has been considerable interest in neural circuits that initiate behavior patterns. For many types of behaviors, this involves decision-making circuits whose primary elements are neither purely sensory nor motor, but represent a higher order of neural pro cessing. Of the large number of studies on such systems, analyses of startle circuits compose a major portion, and have been carried out on systems found throughout the animal kingdom. Startle has been an im portant model because of the reliability of the behavioral act for laboratory study and the accessibility of the underlying neural circuitry. However, probably because of the breadth of the subject, this material has never been reviewed in a comprehensive way that presents the elements com mon to startle circuits in the different animal systems in which they occur. This book presents a diversity of approaches based on a broad back ground of animal groups ranging from the earliest nervous systems in cnidarians to the most recently evolved and advanced in mammals. The behaviors themselves are all short latency, fast motor acts, when consid ered on the time scale of the organism, and involve avoidance or evasion, although in some cases we do not yet completely understand their natural role. These behaviors occur in response to stimuli that have sudden or unexpected onset."

The book presents topics in discrete biomathematics. Mathematics has been widely used in modeling biological phenomena. However, the molecular and discrete nature of basic life processes suggests that their logic follow principles that are intrinsically based on discrete and informational mechanisms. The ultimate reason of polymers, as key element of life, is directly based on the computational power of strings, and the intrinsic necessity of metabolism is related to the mathematical notion of multiset. The switch of the two roots of bioinformatics suggests a change of perspective. In bioinformatics, the biologists ask computer scientists to assist them in processing biological data. Conversely, in infobiotics mathematicians and computer scientists investigate principles and theories yielding new interpretation keys of biological phenomena. Life is too important to be investigated by biologists alone, and though computers are essential to process data from biological laboratories, many fundamental questions about life can be appropriately answered by a perspicacious intervention of mathematicians, computer scientists, and physicists, who will complement the work of chemists, biochemists, biologists, and medical investigators. The volume is organized in seven chapters. The first part is devoted to research topics (Discrete information and life, Strings and genomes, Algorithms and Biorhythms, Life Strategies), the second one to mathematical backgrounds (Numbers and Measures, Languages and Grammars, Combinations and Chances).

The regions of the world which experience a mediterranean type climate, with a cool wet season alternating with a hot dry summer, contain some of the world's most attractive landscapes. In the Old World, the mediterranean landscapes became the cradle of civilization; other mediterranean areas of the world have attracted considerable populations for many centuries. These large human populations have exerted consid erable stress on the fragile ecosystems which developed in these sunny, but droughted, fire-prone land scapes. The mediterranean landscape has thus become one of the most threatened in the world. In recent years much has been learned about the structure and function of mediterranean-type ecosystems (Di Castri and Mooney 1973, Mooney 1977, Thrower and Bradbury 1977, Mooney and Conrad 1977, Specht 1979, 1981, Miller 1981, Di Castri et at. 1981, Conrad and Oeche11982, Queze11982, Margaris and Mooney 1981, Kruger et ai. 1983, Long and Pons 1984, Dell et ai. 1986, Tenhunen et ai. 1987). Much of this research has been fostered under the International Biological Program (IBP), UNESCO Man and the Biosphere Program (MAB) and, recently, the International Society of Mediterranean Ecologists (ISOMED). To facilitate intercontinental comparisons, many of these studies have concentrated on a limited number of intensive sites thought to be representative of a general region."

This practical manual represents a comprehensive, up-to-date compilation of useful chemical ecology techniques and references. Written from the viewpoint of the practitioner, this book and its companion volume on chemical methods describe apparatus and methods, providing detailed discussions of the advantages and limitations of various techniques. Taken together, the volumes provide the information required to isolate and identify biologically active chemicals mediating inter- and intraspecific interactions between organisms from most of the major taxa. Methods in Chemical Ecology: Bioassay Methods covers bioassay techniques from a broad spectrum of species, ranging from microorganisms in aquatic environments to mammals in terrestrial habitats. This volume is designed to assist both ecologists and chemists with the sometimes daunting task of developing bioassay techniques to be used in the isolation and identification of natural products. The contributors, all highly respected active researchers, provide insights into the many pitfalls of bioassay design based on their years of experience. With minimal use of technical jargon, this volume is designed as an indispensable reference manual for graduate students as well as experienced researchers. This volume will also serve as a valuable reference book for researchers in many related disciplines, including animal behavior, natural-products chemistry, ecology, botany/plant sciences, zoology, entomology, marine biology and ecology, and pharmacology.

This book examines the implications of the net zero transition for food and farming in the UK and how these can be managed to avoid catastrophic climate change in the crucial decades ahead. For the UK to meet its international obligations for reducing greenhouse gas emissions, nothing short of a revolution is required in our use of land, our farming practices and our diet. Taking a historical approach, the book examines the evolution of agriculture and the food system in the UK over the last century and discusses the implications of tackling climate change for food, farming and land use, setting the UK situation in an international context. The chapters analyse the key challenges for this transition, including dietary change and food waste, afforestation and energy crops, and low-emission farming practices. This historical perspective helps develop an understanding of how our food, farming and land use system has evolved to be the way that it is, and draws lessons for how the agri-food system could evolve further to support the transition to net zero and avoid catastrophic climate change. Written in a clear and accessible style, this book will be essential reading to students and scholars of food, agriculture and the environment, as well as policymakers and professionals involved climate change policy and the agriculture and food industry.

Matters of Sport is a tribute to Eric Dunning, the leading sports sociologist in the English-speaking world. This book addresses Dunning's contributions to the sociological and historical study of sport, covering key topics such as hooliganism, celebrity and gender relations.

A broad range of leading academics from Europe and North America reflect on the ways in which Dunning's work has influenced their own research and understanding of sport.

This volume was previously published as a special issue of the journal Sport in Society.

This book examines information processing performed by bio-systems at all scales: from genomes, cells and proteins to cognitive and even social systems. It introduces a theoretical/conceptual principle based on quantum information and non-Kolmogorov probability theory to explain information processing phenomena in biology as a whole. The book begins with an introduction followed by two chapters devoted to fundamentals, one covering classical and quantum probability, which also contains a brief introduction to quantum formalism, and another on an information approach to molecular biology, genetics and epigenetics. It then goes on to examine adaptive dynamics, including applications to biology, and non-Kolmogorov probability theory. Next, the book discusses the possibility to apply the quantum formalism to model biological evolution, especially at the cellular level: genetic and epigenetic evolutions. It also presents a model of the epigenetic cellular evolution based on the mathematical formalism of open quantum systems. The last two chapters of the book explore foundational problems of quantum mechanics and demonstrate the power of usage of positive operator valued measures (POVMs) in biological science. This book will appeal to a diverse group of readers including experts in biology, cognitive science, decision making, sociology, psychology, and physics; mathematicians working on problems of quantum probability and information and researchers in quantum foundations.

In the last fifty years our butterfly populations have declined by more than eighty per cent and butterflies are now facing the very real prospect of extinction. It is hard to remember the time when fields and meadows were full of these beautiful, delicate creatures - today we rarely catch a glimpse of the Wild Cherry Sphinx moths, Duke of Burgundy or the even once common Small Tortoiseshell butterflies. The High Brown Fritillary butterfly and the Stout Dart Moth have virtually disappeared. The eminent entomologist and award-winning author Josef H. Reichholf began studying butterflies in the late 1950s. He brings a lifetime of scientific experience and expertise to bear on one of the great environmental catastrophes of our time. He takes us on a journey into the wonderful world of butterflies - from the small nymphs that emerge from lakes in air bubbles to the trusting purple emperors drunk on toad poison - and immerses us in a world that we are in danger of losing forever. Step by step he explains the science behind this impending ecological disaster, and shows how it is linked to pesticides, over-fertilization and the intensive farming practices of the agribusiness. His book is a passionate plea for biodiversity and the protection of butterflies.

Analysis by In Situ Hybridization of Cytokine mRNAS Expression in Thymic Nurse Cells.- Genetic Expression of the C-CBL Proto-Oncogene in Human Thymocytes.- Production and Selection of B Lymphocytes in Bone Marrow: Lymphostromal Interactions and Apoptosis in Normal, Mutant and Transgenic Mice.- Thymic Neuroendocrine Self Peptides and T Cell Selection.- Human Fetal Liver Cells Differentiate into Thymocytes in Chimeric Mouse Fetal Thymus Organ Culture.- Towards Identification of Memory B Cells in Human Tonsils.- Prolonged IL-4 Treatment Decreases the TNP-Specific Memory Formation for IgG1.- Selection of Anti-Arsonate Idiotype (CRIA) in A/J Mice by the Immune Network.- The Life History and Functional Roles of Accessory Cells.- The Role of Macrophages in Regeneration of Splenic Tissue after Autologous Transplantation in Rat.- In Vivo Antigen Presentation Capacity of Dendritic Cells from Oral Mucosa and Skin Draining Lymph Nodes.- Liposome Mediated Modulation of Macrophage Functions.- In Vivo gp39-CD40 Interactions Occur in the Non-Follicular Compartments of the Spleen and Are Essential for Thymus Dependent Antibody Responses and Germinal Center Formation.- The Role of Dendritic Cells in the Uptake and Presentation of Oral Antigens.- Blockage of Thymic Medullary Epithelial Cell Activation: In Vivo Consequences.- Half-Lives of Antigen/MHC Class II Complexes Differ between Distinct Organ Microenvironments.- Regulation of Neural and Peripheral Cytokine Production by Benzodiazepines and Endogenous Anxiogenic Peptides.- Could ACTH be of Prime Importance in Rapidly Altering the Thymocyte Composition in the Thymus?.- Adrenergic and Cholinergic Regulation of Apoptosis and Differentiation of Thymic Lymphocytes.- Autoimmune lpr and gld Mice: Models of Abnormal Adhesion Molecule Regulation and Defective Lymphocyte Traffic.- Vascular Addressin Expression in Peyer's Patches: An in Vivo Study of Site-Associated Regulation.- Domain 5 of the Intercellular Adhesion Molecule-1 (ICAM-1) Is Involved in Adhesion of B-Cells and Follicular Dendritic Cells.- Modifications of the Expression of Homing and Adhesion Molecules in Infiltrated Islets of Langerhans in Nod Mice.- Characterization of Giant Perivascular Spaces in the Thymus of the Nonobese Diabetic Mouse.- Adhesion Molecule PECAM-1/CD31 Is Expressed on Defined Subsets of Murine LAK Cells.- Intrathymic Gap Junction-Mediated Communication.- Complement and Antibody Enhance Binding and Uptake of HIV-1 by Bone Marrow Cells.- Follicular Dendritic Cells (FDC) Are Not Productively Infected with HIV-1 in Vivo.- Lymph Node Pathology in Experimental FIV Infection.- Lymphocyte Lifespan in Murine Retrovirus-Induced Immunodeficiency.- Analysis of HIV Infections in Human Macrophage-Like Cell Lines.- The Pivotal Role of the Immunoglobulin Receptor of Tumor Cells from B Cell Lymphomas of Mucosa Associated Lymphoid Tissue (MALT).- TNF?- Is Involved in the Mechanism of Murine Thymic Lymphoma Prevention by Bone Marrow Grafting.- Analysis of Germinal Centres in the Immune Response to Oxazolone.- Cytokine Responsiveness of Germinal Center B Cells.- The Differences in Survival and Phenotype between Centroblasts and Centrocytes.- In Vivo Localisation Patterns and Cell-Cell Interactions of Cytokine Producing T-Cells and Specific Antibody Forming B-Cells.- DHEAS Enhances Germinal Center Responses in Old Mice.- Cellular Origin of Follicular Dendritic Cells.- Germinal Centers Develop at Predilicted Sites in the Chicken Spleen.- Expression and Function of DRC-1 Antigen.- The Appendix Functions as a Mammalian Bursal Equivalent in the Developing Rabbit.- Development of Components of the Mucosal Immune System in SCID Recipient Mice.- Many Newly Formed T Lymphocytes Leave the Small Intestinal Mucosa via Lymphatics.- Analysis of IgA-Producing Hybridomas Derived from Peritoneal Bl Cells.- Modulation of the Neonatal IgA Response to Enteric Antigens by Maternal Antibody.- Antibody-Forming Cells (AFCs) in the Lung Lymphoid Tissue afte...

Visualization technology is becoming increasingly important for medical and biomedical data processing and analysis. The interaction between visualization and medicine is one of the fastest expanding fields, both scientifically and commercially. This book discusses some of the latest visualization techniques and systems for effective analysis of such diverse, large, complex, and multi-source data.

Insights and analysis that challenge current thought on consumer branding theory and strategy Pharmaceutical companies need to go beyond simply relying on strong sales forces and innovative research and development to succeed. Effective branding strategy is essential. PharmaceuticalsWhere's the Brand Logic?: Branding Lessons and Strategy discusses in detail the application of current consumer branding theory to pharmaceutical marketing. This comprehensive book pulls information from fast moving consumer goods (FMCG) research and brand theory and applies it to the pharmaceutical world. It looks at branding on multiple levels within the pharmaceutical industry, including the industry brand, the corporate brand, the franchise brand, and the global and local product brand. Practical strategies are extensively explained and future challenges facing the pharmaceutical industry are explored, all geared to help any pharmaceutical professional to successfully market his or her brand. PharmaceuticalsWhere's the Brand Logic?: Branding Lessons and Strategy may well become a daily reference for anyone in the industry, providing in a single volume a framework for the organization of a brand portfolio for any pharmaceutical company. This unique resource challenges traditional thought about the concept of branding in the pharmaceutical industry, examining several of the most difficult branding theory issues. This helpful guide provides several figures to fully explain data. Topics in PharmaceuticalsWhere's the Brand Logic?: Branding Lessons and Strategy include: what is branding how is branding applied to the FMCG and pharmaceutical industries corporate brandsand how they can be leveraged franchise branding as a business strategy developing and sustaining pharmaceutical brands over time saving the credibility of the pharmaceutical industry changing the pharmaceutical business model to use branding as a strategic tool much, much more PharmaceuticalsWhere's the Brand Logic?: Branding Lessons and Strategy provides the information and tools to help gain the competitive edge in a tough marketplace. This is an invaluable resource for anyone in the global pharmaceutical industry, including marketing personnel, senior management, general managers, strategy groups, and training departments.

The role of competition within communities, in shaping the structure and composition of the community matrix itself and in influencing day to day functioning of the system is particularly controversial. This book offers a synthesis of these arguments and provides an overview of existing knowledge about competition and organizing that knowledge in such a way that new research paths are suggested. The author presents an original and at times controversial view of competition and its role in ecological communities, not only summarizing what is known but stressing the unknowns, describing unresolved problems and suggesting avenues for further research.

This set comprises 40 volumes covering nineteenth and twentieth century European and American authors. Available as a complete set, mini boxed sets (by theme) or as individual volumes.

Invasive species have come to dominate 3% of the Earth 's ice-free surface, constituting one of the most serious ecological and economic threats of the new millennium, and freshwater systems are particularly vulnerable. This book examines the identity, distribution, and impact of freshwater non-indigenous species and the dynamics of their invasion. It focuses on old and new invaders and provides a starting point for further research.

Who owns your sex organs? Different cultures today and in different epochs have given a variety of answers to this question. It may seem self evident that every individual owns and has sovereignty over his or her own body parts, such as the head, legs, nose, stomach, pancreas, and other body parts. The sex organs, however, seem to be an exception. Even though they are as much an integral part of the individual as a leg or a liver, the sex organs are unique in that many cultures have established laws and taboos over the use and even the mere display of the sex organs. Thus, certain cultures have placed constraints over the individual's ownership of his or her sex organs and actively regulate and restrict the individual's access and use of those organs. In other cultures, the question of ownership of the sex organs is more decisively answered. In any culture where circumcision to any degree of either the male or female is practiced, permitted, encouraged, or even merely tolerated, it is clear that the individual is not considered to own his own sex organs. In the United States today, the medical establishment has created an is considered acceptable and desirable that anyone for environment where it any reason can authorize or execute the amputation of the foreskin from a male child's penis."

Coral reefs have shaped the surface of our planet far more than has any other ecosystem. They are dynamic systems, producing limestone at the rate of 400-2,000 tons per hectare per year, and influencing the chemical balance of the world's oceans. Coral reefs have been around since before the prairies or other ecosystems of flowering plants existed, yet they vanish about a million years before other groups of organisms each time there is a global mass extinction. They return after each catastrophe, however, following a long period of absence. Although coral reefs are the most productive communities in the sea, the fisheries of coral reefs are among the most vulnerable to overexploitation. Despite having the power to create the most massive structures in the world made by living creatures (including man), the thin veneer of living tissue of coral reef is particularly sensitive to natural disturbances and effects of human activities. Coral reefs are the first to go during periods of climate change, but they have always come back. This combination of attributes, creative power and fragility, resilience and sensitivity, makes management of coral-reef systems a challenge to science. Over 70% of the coral reefs in the Caribbean and Asian waters have been degraded, and perhaps a third of the 400 species of corals in Japanese waters are in danger of local extinction unless effective coastal management practices are established. This book presents what is known about factors that shift the balance between accretion and erosion, recruitment and mortality, stony corals and filamentous algae, recovery and degradation--the life and death of coral reefs. Insight into the factors controlling thedirection of these processes is essential for appropriate management decisions.

Exam Board: Edexcel Level: A level Subject: Science / Biology First teaching: September 2015 First exams: June 2017 Revise smart and save! Designed for hassle-free classroom and independent study, our Revision Guides are designed to complement the Student Books with a range of specially designed features such as: One-topic-per-page format Worked examples with exemplar answers 'Now Try This' practice questions Knowledge checks and skills checks Includes FREE online edition! With a one-to-one page correspondence between this Revision Guide and the companion Edexcel AS/A level Biology Revision Workbook, the hugely popular REVISE series offers the best value available for A level students.

This clear, concise Complete Revision & Practice book from CGP is a perfect way to prepare for the Edexcel A A-Level Biology exams - it covers every topic from both years of the course. It's fully up-to-date for the new exam specifications for 2015 and beyond, with straightforward explanations, helpful examples and full-colour diagrams throughout. Practice questions and exam-style questions (with answers) are included for every topic, and the book is rounded off with a section of in-depth advice on Practical Skills. And finally, a free Online Edition of the whole book is included - just use the code printed inside the book to access it on your PC, Mac or tablet!

Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.

Living Marine Resources provides a thorough, up-to-date introduction to all aspects of fisheries science. This clearly written text offers insight into a topic of increasing importance--the wise utilization and management of sea fisheries to maximize production without exceeding their carrying capacity. Adoption of the approaches presented will improve the conservation and management of the many world fisheries that are suffering from years of inefficient practices. The book is divided into five sections, beginning with an introduction to the ocean environment and the various resource species. Part two examines fisheries biology, including age, growth, fecundity, and mortality, enabling readers to appreciate yield models designed to give estimates of maximum sustainable yield and maximum economic yield. The third part covers gear, methods, and landings and includes material on the handling and processing of seafood as well as aquaculture. In part four, yield models are presented to introduce students to theories on population dynamics, stock assessment, and management. The book concludes with coverage of recreational fisheries, including socioeconomic importance, catch and effort research, management techniques, and their interface with commercial fisheries. Living Marine Resources is an invaluable introduction to the subject for advanced undergraduate and graduate students of fisheries science. In addition, the material presented will be valuable to fishery and social scientists, fishery officers and administrators, and students in biology, engineering, economics, and law.