The ease of use of the programs in the application to ever more complex cases of disease and pestilence. The lack of need on the part of the student or modelers of mathematics beyond algebra and the lack of need of any prior computer programming experience. The surprising insights that can be gained from initially simple systems models.

Determinism, holism and complexity: three epistemological attitudes that have easily identifiable historical origins and developments. Galileo believed that it was necessary to "prune the impediments" to extract the mathematical essence of physical phenomena, to identify the math ematical structures representing the underlying laws. This Galilean method was the key element in the development of Physics, with its extraordinary successes. Nevertheless the method was later criticized because it led to a view of nature as essentially "simple and orderly," and thus by choosing not to investigate several charac teristics considered as an "impediment," several essential aspects of the phenomenon under investigation might be left out. The Galilean point of view also contains an acknowledgement of the central role played by the causal nexus among phenomena. The mechanistic-deterministic de scription of reality - for instance, a la Laplace - although acknowledging that it is not possible to predict phenomena exactly owing to unavoid able measurement error, is based on the recognition of the their causal nature, even in an ontological sense. Consequently, deterministic predic tion became the methodological fulcrum of mathematical physics. But although mechanistic determinism has had and, in many cases, still has, considerable success in Physics, in other branches of science this situa tion is much less favourable."

During the last couple of years, fractals have been shown to represent the common aspects of many complex processes occurring in an unusually diverse range of fields including biology, chemistry, earth sciences, physics and technology. Using fractal geometry as a language, it has become possible to get a deeper insight into previously intractable problems. Among many others, a better understanding of growth phenomena, turbulence, iteractive functions, colloidal aggregation, biological pattern formation and inhomogenous materials has emerged through the application of such concepts as scale invariance, self-affinity and multifractality.This volume contains a selection of high quality papers that discuss the latest developments in the research of fractals. It is divided into 5 sections and contains altogether 64 papers. Each paper is written by a well known author or authors in the field. Beginning each section is a short introduction, written by a prominent author, which gives a brief overview of the topics discussed in the respective sections.

That children need nature for health and well-being is widely accepted, but what type of nature? Specifically, what type of nature is not only necessary but realistically available in the complex and rapidly changing worlds that children currently live in? This book examines child-nature definitions through two related concepts: the need for connecting to nature and the processes by which opportunities for such contact can be enhanced. It analyses the available nature from a scientific perspective of habitats, species and environments, together with the role of planning, to identify how children in cities can and do connect with nature. This book challenges the notion of a universal child and childhood by recognizing children's diverse life worlds and experiences which guide them into different and complex ways of interacting with the natural world. Unfortunately not all children have the freedom to access the nature that is present in the cities where they live. This book addresses the challenge of designing biodiverse cities in which nature is readily accessible to children.

This book, written by an international team of experts, introduces the reader to various aspects of complexity theory and its applications. It illustrates the latest trends in science to go beyond the mechanistic Newtonian view of the world by shifting the focus to self-organization, adaptation, and emergent phenomena. The authors discuss these properties of complex systems in biology, ecology and chemistry along with the structure and interconnectedness of the "layers" of complexity. The qualitative description is complemented by a discussion of methods for complexity quantification. Networks are covered in detail as a universal language of the complex world.

General readers, as well as undergraduate and graduate students and researchers in life sciences, chemistry, and nanotechnology will find this book to be of great interest.

This NATO Advanced Study Institute (co-sponsored by FEBS and INTAS) under the title "Chemical Probes in Biology" was designed to summarize and disseminate recent expert knowledge regarding a deeper understanding ofbiological phenomena on a molecular level. Such scientific activities -frequently termed Bio-organic Chemistry or Chemical Biology are constituting a highly interdisciplinary branch of chemistry beyond the traditional ways in which chemists and biologists have been working in the past. Thus, on this occasion we were bringing together senior experts from the disciplines of Chemistry and Biology in order to amalgamate their diverse yet basically common interests in this area. Ultimate goal was - next to an exchange of information between the two scientific cultures - the communication ofexciting possibilities in interdisciplinary research to the young scientists present. The meeting was held in the Anargyros and Korgialenios School on the Island ofSpeteses, Greece from 18-30 August 2002. The ASI was attended by a total of 91 scholars from 23 different countries. A group of 27 speakers presented a series of 34 highly stimulating, informative and educational lectures covering a broad range of topics relevant to the general theme ofthis meeting: Science at the InteifaceofChemistry, Biology and Medicine. The lectures were complemented by a total of 89 posters presented by the young scholars and a series of short lectures derived thereof This was clearly one ofthe highlites of the meeting creating a lively atmosphere of interaction and intellectual creativity - typical phenomena for the whole meeting."

An unprecedented step-by-step approach to the Bar/Bat Mitzvah Planning experience, this manual treats the ceremonies as Jewish religious occasions, wedding the ethical insights of religions to a meaningful and tasteful event. "Handsome and comprehensive".--Washington Post.

There has been a great upsurge in interest in light microscopy in recent years due to the advent of a number of significant advances in microscopy, one of the most important of which is confocal microscopy. Confocal microscopy has now become an important research tool, with a large number of new fluorescent dyes becoming available in the past few years, for probing your pet structure or molecule within fixed or living cell or tissue sampies. Many of the people interested in using confocal microscopy to further their research do not have a background in microscopy or even cell biology and so not only do they find considerable difficulty in obtaining satisfactory results with a confocal microscope, but they may be mislead by how data is being presented. This book is intended to teach you the basic concepts ofmicroscopy, fluorescence, digital imaging and the principles of confocal microscopy so that you may take full advantage ofthe excellent confocal microscopes now available. This book is also an excellent reference source for information related to confocal microscopy for both beginners and the more advanced users. For example, do you need to know the optimal pinhole size for a 63x 1. 4 NA lens? Do you need to know the fluorescence emission spectrum of Alexa 568? Access to the wealth of practical information in this book is made easier by using both the detailed index and the extensive glossary.

Wearable Sensing and Intelligent Data Analysis for Respiratory Management highlights the use of wearable sensing and intelligent data analysis algorithms for respiratory function management, offering several potential and substantial clinical benefits. The book allows for the early detection of respiratory exacerbations in patients with chronic respiratory diseases, allowing earlier and, therefore, more effective treatment. As such, the problem of continuous, non-invasive, remote and real-time monitoring of such patients needs increasing attention from the scientific community as these systems have the potential for substantial clinical benefits, promoting P4 medicine (personalized, participative, predictive and preventive). Wearable and portable systems with sensing technology and automated analysis of respiratory sounds and pulmonary images are some of the problems that are the subject of current research efforts, hence this book is an ideal resource on the topics discussed.

Jim Green 1.1 THE THAMES ESTUARY: A PERSONAL VIEW For almost 50 years I have lived close to the Thames estuary (Figure 1.1). In the early 1950s, from our flat in Pimlico, we could walk along the embankment opposite Battersea Power Station. At low tide, the exposed mud had large red patches caused by the haemoglobin in innumerable tubificid worms. These formed the basis of a minor trade. Men with waders and sieves would collect the worms and sell them to the aquarium trade as food for fishes.The superabundance of these worms depended on the gross organic pollution of this reach of the Thames. Towards the end of the 1950s we moved to Teddington, within a few minutes' walk from the lock. Casual observation of the birds on the river indicates an increase in the piscivores over the last 20 years.Cormorants tPhalacrocorax carbo) are regularly seen, and grey herons (Ardea cinerea) are more abundant. On a good day it is possible to see up to eight herons around the weir and below the lock. Another bird that is now common place in the area is the great-crested grebe (Podiceps cristatus).The regular mallard (Anas platyrhynchos)and Canada geese (Branta canadensis)are some times joined by tufted duck (Aythafuligula)and mandarin (Aixgalericulata)."

Mapping Biology Knowledge addresses two key topics in the context of biology, promoting meaningful learning and knowledge mapping as a strategy for achieving this goal. Meaning-making and meaning-building are examined from multiple perspectives throughout the book. In many biology courses, students become so mired in detail that they fail to grasp the big picture. Various strategies are proposed for helping instructors focus on the big picture, using the need to know' principle to decide the level of detail students must have in a given situation. The metacognitive tools described here serve as support systems for the mind, creating an arena in which learners can operate on ideas. They include concept maps, cluster maps, webs, semantic networks, and conceptual graphs. These tools, compared and contrasted in this book, are also useful for building and assessing students' content and cognitive skills. The expanding role of computers in mapping biology knowledge is also explored.

This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac electrophysiology, physics of excitable media, applied mathematics and high performance scientific computing and visualisation. The author uses computer models to provide insights into the underlying mechanisms of the genesis of atrial fibrillation and develops novel techniques for the monitoring of atrial tachycardia.