Health sciences librarianship today demands a balance among computer files, human ingenuity, and print sources. The many information sources presently available enable health sciences librarians to do a better job, but that job has also become correspondingly more difficult. This professional reference surveys the various types of print and electronic resources important to the health sciences and provides valuable practical advice to librarians for meeting the information needs of researchers, practicing physicians, and other health professionals. Health sciences librarianship today demands a balance among electronic files, human ingenuity, and print sources. Thanks to computerization and telecommunications, librarians can do much more now than just a few years ago. While the tremendous growth in available resources has enabled librarians to provide more thorough information to patrons, the process of doing so has become correspondingly more complex. While librarians still need to use many traditional skills, they must also develop new ways of finding and utilizing information. This professional reference surveys the field of health sciences librarianship and provides extensive practical advice to assist health sciences librarians in meeting the information needs of their patrons. Because journal literature is the principal medium of information in the health sciences, the book begins with an examination of the roles that journals play as well as the large proportion of the library budget that they consume. The volume then discusses techniques of searching journal literature, such as print and electronic indexing and abstracting tools. Additional chapters are devoted to the selection and organization of health sciences books, and reference tools and services. Special attention is given to the electronic distribution of biomedical information. With important sources of health information now becoming available via the Internet, this book provides a point of departure to evaluate those sources. The final chapter discusses the various environments that shape health sciences librarianship, such as library settings, professional associations, and economic contexts.

In the relatively short period since "Cryptosporidium" was recognised as a human pathogen, and that it could be transmitted in water as well as directly between animals and people, it has been the subject of intense investigations. Its status as an opportunistic pathogen, especially in AIDS patients, and the lack of effective anti-cryptosporidial drugs have served to emphasise the public health importance of this organism. This has to some extent overshadowed the fact that "Cryptosporidium "is also an important pathogen of domestic animals and wildlife.

In recent years, the application of molecular biology and culture techniques have had an enormous impact on our understanding of the aetiological agents of cryptosporidial infections and our ability to study the causative agents in the laboratory. As a consequence, a wealth of information and novel data has been produced during the last 3-4 years, particularly in the areas of taxonomy, biology, pathogenesis, epidemiology - particularly zoonotic and water borne transmission, and treatment.

It is thus very timely to bring together in this book the international research community involved to review the major advances in research and identify the important research priorities for the future, thus enabling as wide an audience as possible to benefit from and share in this comprehensive look at "Cryptosporidium "and cryptosporidiosis.

This volume reviews the techniques Forster Resonance Energy Transfer (FRET) and Fluorescence Lifetime Imaging Microscopy (FLIM) providing researchers with step by step protocols and handy hints and tips. Both have become staple techniques in many biological and biophysical fields.

Living systems exhibit a fundamental contradiction: they are highly stable and reliable, yet they have the capacity to adapt to changing environmental conditions. This paradoxical behavior arises from the complexity of life--a high degree of order and cooperation that emerges from relatively simple interactions among cellular components. The Complexity Paradox proposes inventive, interdisciplinary approaches to maintaining health and managing and preventing disease by considering the totality of human biology, from the cellular level on up to entire populations of individuals. From the perspective of complexity, which acknowledges that there are limits to what we can know, Kenneth L. Mossman opens the door to understanding essential life processes in new and extraordinary ways. By tying together evolution, functional dynamics, and investigations into how the body processes energy and uses genetic information, Mossman's analysis expresses a unified theory of biology that fills a critical niche for future research in biology, medicine, and public health.

On the Origin of Species, published in 1859, is widely accepted as the seminal work in modern biology. Through careful observation, Charles Darwin explains how traits can be selected for within a population. This is easily observed in the artificial selection of farm animals, for instance. Darwin's theory caused an uproar that can still be heard today by refuting the Christian doctrine of created breeds, in which all species that exist now have always existed just as they are. It is the very publication of this work that gave Charles Darwin his place of prominence in the history of the theory of evolution, because while he was not the first to suggest such a mechanism, his book and its exhaustive studies made the information widely available. English scientist, naturalist, and geologist CHARLES DARWIN (1809-1882) revolutionized science, especially biology, with his theory of evolution through natural selection. As a passenger aboard the Beagle, Darwin became intrigued by the existence of different species in different geographical locations, which aided in the development of his theory. In addition to The Origin of Species, he is also remembered for The Descent of Man, and Selection in Relation to Sex and The Expression of the Emotions in Man and Animals.

This book presents recent research results relating to applications of nonlinear dynamics, focusing specifically on four topics of wide interest: heart dynamics, DNA/RNA, cell mobility, and proteins. The book derives from the First BCAM Workshop on Nonlinear Dynamics in Biological Systems, held in June 2014 at the Basque Center of Applied Mathematics (BCAM). At this international meeting, researchers from different but complementary backgrounds, including molecular dynamics, physical chemistry, bio-informatics and biophysics, presented their most recent results and discussed the future direction of their studies using theoretical, mathematical modeling and experimental approaches. Such was the level of interest stimulated that the decision was taken to produce this publication, with the organizers of the event acting as editors. All of the contributing authors are researchers working on diverse biological problems that can be approached using nonlinear dynamics. The book will appeal especially to applied mathematicians, biophysicists, and computational biologists.

Examines harmonization of the US Federal Food, Drug, and Cosmetic Act with international regulations as they apply to human drug and device development, research, manufacturing, and marketing. The Second Edition focuses on the new drug approval process, cGMPs, GCPs, quality system compliance, and corresponding documentation requirements. Written in a jargon-free style, it draws information from a wide range of resources. It demystifies the inner workings of the FDA and facilitates an understanding of how it operates with respect to compliance and product approval. FDA Regulatory Affairs: provides a blueprint to the FDA and drug, biologic, and medical device development offers current, real-time information in a simple and concise format contains a chapter highlighting the new drug application (NDA) process discusses FDA inspection processes and enforcement options includes contributions from experts at companies such as Millennium and Genzyme, leading CRO's such as PAREXEL and the Biologics Consulting Group, and the FDA Three all-new chapters cover: clinical trial exemptions advisory committees provisions for fast track

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For animal behavior, ethology, and behavioral ecology courses, this laboratory manual is the first of its kind in this subject area that guides students through the diverse and fascinating fields of behavioral and ethological studies, employing a wide array of organisms as model systems for the study of behavior. Students participate in the development of hypothesis and turn the recording, analysis, and interpretation of data into an active and engaging process.
A teacher-friendly companion website provides extensive teaching notes on the background to each lab project, tips and hints for successful project presentation, sources for studying organisms, ideas for variations in labs, and alternate study organisms. With fresh new ideas, Field and Laboratory Exercises in Animal Behavior brings this field to life for students!
* Provides fully developed and tested laboraty exercises
* Offers both field and lab experiences- adaptable for fall, spring, or summer courses
* Laboratories emphasize student thought and involvement in experimental design
* Includes an online supplement to the manual for teachers

By using nanotechnological methods, we can now poke around protein molecules, genes, membranes, cells and more. Observation of such entities through optical and electron microscopes tempt us to touch and manipulate them. It is now possible to do so, and scientists around the world have started pulling, pushing and cutting small structures at the base of life processes to understand the effect of our hand work.
The book describes the physical properties of such life supporting structures from the molecular level with a special emphasis on their designs based on the mechanical strength and flexibility, membrane and other biological nanostructures.

- Describes the basic mechanical features of proteins, DNA, cell membrane and other biological nanostructures
- Explains the basic concepts and mathematics of elementary mechanics needed to understand and perform experimental work

With a claim to be the first work to document in detail the history of allelopathy, Willis s text provides an account of the concept of allelopathy as it has occurred through the course of botanical literature from the earliest recorded writings to the modern era. A great deal of information is presented here in a consolidated and accessible form for the first time. The book offers a unique insight into the historical factors which have influenced the popularity of allelopathy.

The advent of powerful processing technologies and the advances in software development tools have drastically changed the approach and implementation of computational research in fundamental properties of living systems through simulating and synthesizing biological entities and processes in artificial media. Nowadays realistic physical and physiological simulation of natural and would-be creatures, worlds and societies becomes a low-cost task for ordinary home computers. The progress in technology has dramatically reshaped the structure of the software, the execution of a code, and visualization fundamentals. This has led to the emergence of novel breeds of artificial life software models, including three-dimensional programmable simulation environment, distributed discrete events platforms and multi-agent systems. This second edition reflects the technological and research advancements, and presents the best examples of artificial life software models developed in the World and available for users.

Transcendental phenomenology presumed to have overcome the classic mind-body dichotomy in terms of consciousness, yet, according to progress in scientific studies, the biological functions of the brain seem to appropriate significant functions attributed traditionally to consciousness. Should we indeed dissolve the specificity of human consciousness by explaining human experience in its multiple sense-giving modalities through the physiological functions of the brain? The present collection of studies addresses this crucial question challenging such "naturalizing" reductionism from multiple angles. In search for the roots of "The Specifically Human Experience" (Bombala), moving along the line of "Animality and Intellection"(Gosetti-Ferencei), "Naturalistic Attitude and Personalistic Attitude"(Villela-Petit), and numerous other perspectives, we arrive at a novel proposal to explain the scholar functional differentiation of conscious modalities. We reach their source in the ontopoietic thread conducting the Logos of Life in its stepwise "Evolutive Unfolding"(Carmen Cozma), and in "sentience" as its quintessential core of further irreducible continuity (Tymieniecka) dispelling dichotomies and reductionisms.

Papers by:
Grahame Lock, Anna-Teresa Tymieniecka, Daniela Verducci, Ted Toadvine, Mary Trachsel, Martin Holt, Mary Jeanne Larrabee, Leszek Pyra, Bronislaw Bombala, Konrad Rokstad, Ilja Maso, Nancy Mardas, Jennifer Anna Gosetti-Ferencei, Maria Villela-Petit, Mara Stafecka, Carmen Cozma, Francesco Totaro, Andreas Brenner, Sinan Kadir Celik, Osvaldo Rossi, Maria Manuela Brinto Martins, Elga Freiberga, Klymet Selvi, J.C. Couciero-Bueno, Patricia Trutty-Coohill, Walter Lammi, Ljudmila Molodkina, Martin Nkafu Nkemnkia.