The consequences of childhood obesity are serious and far reaching, with both physical and psychological components that add to its complexity. Childhood Obesity: Contemporary Issues provides an up-to-date account of the increase of obesity in children, its causes, and its prevention. The expert editorial panel has chosen contributors with considerable practical and research experience. They explore why childhood obesity is so difficult to prevent and treat. Focusing less on clinical issues and more on environmental factors, the book brings together social, psychological, biological, and socio-biological approaches to the experience and problem of obesity. Delineating the scope and impact of childhood obesity, the book provides a unique view of the obese child. It examines the link between food intake and physical activity, which are the immediate determinants of energy balance, and discusses how to measure and assess them. The World Health Organization describes obesity as one of today's most blatantly visible - yet most neglected - public health problems. This book highlights obesity in children and discusses the need to develop multifactorial and multi-agency strategic plans to contain this epidemic.

Comprehensively revised and updated, this 2nd Edition of the Year 1 & AS Student Book is endorsed by Eduqas, offering high quality support you can trust. // It covers Component 1 and Component 2 from the Eduqas Biology for A Level Year 1 and AS specifications. // Straightforward and concise coverage of the specification, so you can be confident you are covering what's needed for exam success. // New 'Test Yourself section' at the end of each chapter reinforces knowledge with answers provided in the book. // Includes detailed explanations of the Assessment Objectives with examples of how the AOs are approached in exam questions. // New section on 'Answering exam questions' at the end of each unit gives guidance on command words and how to approach each question. // New 'Exam Practice questions' at the end of each unit are taken from actual Eduqas past papers with answers provided in the book // New 'Theory Check' feature accompanies the practical tasks in the book and helps students check their understanding of biology in relation to practical tasks. // Enhanced support for practical skills enable you to embed your understanding of practical work. // Increased maths support with maths skills and techniques regularly tested throughout. // Clear explanations and diagrams throughout.

First published in 2003. Routledge is an imprint of Taylor & Francis, an informa company.

While simultaneous breakthroughs occurring in molecular biology and nanoscience/technology will ultimately revolutionize all of medicine, it is with our efforts to prevent, diagnose, and treat cancer that many of the most dramatic advances will occur. In support of this potential, the U.S. National Cancer Institute (NCI) established the Alliance for Nanotechnology in Cancer in 2004 and pledged $144.3 million in funding over the next five years. Edited by one of the most dynamic pioneers in the field, Nanotechnology for Cancer Therapy focuses on those nanoscientific and nanotechnological strategies that are evolving as the most promising for the imaging and treatment of cancer. Among the various approaches considered, nanotechnology offers great possibilities for the targeted delivery of drugs and genes to tumor sites and the ultimate replacement of those chemotherapeutic agents so compromised by side effects. Within this volume, the expertise of world-renowned academic and industrial researchers is brought together to provide a comprehensive treatise. Composed of 38 chapters, the book is divided into 7 sections that cover - Fundamentals of targeting strategies, nanotechnology characterization for cancer therapy, and USFDA guidelines on approval of nanotechnology products Polymeric conjugates used for tumor-targeted imaging and delivery, including imaging to evaluate therapeutic efficacy Polymeric nanoparticle systems that emphasize biodegradable, long-circulating nanoparticles for passive and active targeting Polymeric micellar assemblies, where sophisticated chemistry is leading to novel nanosystems that can provide efficient delivery to tumors Dendritic nanostructures used for cancer imaging and therapy Liposome-based delivery systems -- the oldest nanotechnology method employed in cancer therapy Other lipid nanosystems used for targeted delivery, including those tha

Since our first manned space flights we have learned much about how the human body adapts to the space environment and in particular, to the absence of gravity. Today, space research provides a better understanding of our physiological response mechanisms to microgravity. Space and Life: An Introduction to Space Biology and Medicine describes the results of space research in the context of core concepts in human physiology to depict the effects of both long-term and short-term absence of gravity on the human body. The book explains the scientific basis for the physiological reactions so common to astronauts who experience zero gravity, such as bone calcium loss, puffy faces, and nausea. It includes discussions of cosmic rays, cells, plants, embryonic development, and the origins of life on Earth from a space research standpoint. Updating the current knowledge about how the human body adapts to the space environment and the absence of gravity, this book is ideal for space research scientists, physiologists, NASA employees, and students involved in space study.

This book compiles information relevant to understanding soybean production processes and condenses it into a single volume. The authors identify production practices and bring together diverse information that suggests ways for producers to better utilize the soil and climatic resources of the midsouthern U.S. to enhance production of this valuable and versatile crop. This publication makes a special effort to focus on information that will enhance soybean production in the midsouth, where yields have been lower than those in the upper midwester n portion of the U.S., however, much of the information, such as statistics and crop models, will be applicable to other regions, from Texas to the Carolinas.

Published in 1994, this book examines a small segment of the medical technology innovation process to characterize the manner in which the federal government influences small business-based investigators to participate or withdraw from the medical technology innovation process. It provides an historical account of the federal government's involvement in biomedical technology research and development, and traces the social and economic significance of this involvement.

This superb Student Book has everything students will need for success in Year 2 of AQA A-Level Biology! It contains in-depth, accessible notes explaining every topic, backed up with clear diagrams, photographs, tips and worked examples. To test students' knowledge and understanding, there are practice questions and exam-style questions throughout the book (with detailed answers included). There's also plenty of helpful guidance on Maths Skills and Practical Investigations, plus indispensable advice for success in the final exams. Looking for more help with the maths you'll need for A-Level Biology? Try our Essential Maths Skills book!

Analyzes how the technology and commercial practices of cultivation affect the nutritive value of certain fish, molluscs, crustacea, and freshwater plants. Organized to reflect the sequence from growth, harvest, and capture, through transportation, storage, and processing, to packaging and distribut

The Routledge Companion to Biology in Art and Architecture collects thirty essays from a transdisciplinary array of experts on biology in art and architecture. The book presents a diversity of hybrid art-and-science thinking, revealing how science and culture are interwoven. The book situates bioart and bioarchitecture within an expanded field of biology in art, architecture, and design. It proposes an emergent field of biocreativity and outlines its historical and theoretical foundations from the perspective of artists, architects, designers, scientists, historians, and theoreticians. Includes over 150 black and white images.

Knowing how to deal with the regulatory issues, understanding the impacts of cleanliness, and recognizing the affect that poor facility layout will have on GMP spaces are only some of the issues an experienced Project Manager must focus on. Completely revised and updated, Sterile Product Facility Design and Project Management, Second Edition provides comprehensive guidance on how to develop and execute biotech and other sterile drug facilities based on current industry best practices. Each chapter highlights a specific issue centered on managing biotech facilities projects in a GMP environment. The author uses real-world examples of common industry practice to lead you through the idiosyncrasies of a biotech project in an effort to answer some of the more common, and often perplexing, questions that can stand in the way of success. You get a mini seminar on each topic covered. Breaking the project life-cycle into four phases, the text takes you through each phase from the Project Manager's viewpoint. Unlike other books that cover design, technology, and validation in general terms, this book addresses the industry specific issues that make biotech facilities so costly and difficult to deliver. It puts the pieces of the puzzle together in a manner that increases your opportunity for success.

It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, "How can we use computational methods to improve the success rate in drug development?" Computer Techniques in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source.

A state-of-the-art handbook of statistical analysis for use in the pharmaceutical industry. Areas covered in this reference/text include: bioavailability, repeated-measures designs, dose-response, population models, multicenter trials, handling dropouts, survival analysis, robust data analysis, cate

Rediscover the science and philosophy of behavior In Science and Philosophy of Behavior: Selected Papers, distinguished researcher W. M. Baum delivers an expansive collection of incisive papers setting out a new paradigm of thinking about behavior. The book offers only articles that put forward a philosophical and theoretical framework for an effective natural science of behavior. Quantitative analysis is largely avoided (except for a paper on, of all things, avoidance). Organized into three parts, the author explains the flow-like nature of behavior and its link to evolution, as well as descriptions of a pure form of behaviorism that correct some flaws in B.F. Skinner's seminal works. The book also links behaviorism to anthropology in its final section. Readers will also find: Fulsome descriptions of the molar nature of behavior and why the molecular view is misguided Re-imaginations of the concept of reinforcement, including considerations of allocation, induction, and contingency Explorations of the links between behavior analysis and Darwinian evolutionary processes An essential critique--and reorganization--of behavior theory and philosophy, Science and Philosophy of Behavior: Selected Papers is a controversial, fascinating, and eye-opening journey through a half-century of transformational work in the field.

Different from other books, this unique volume presents basic toxicology principles and applications in a sophisticated yet nontechnical style. It provides an understanding of both the strengths and limitations of the discipline of toxicology and its benefits. This primer is valuable for virtually any non-toxicologist.

Showcasing a discussion of the experimental process and a review of basic statistics, this volume provides methodologies to identify general data distribution, skewness, and outliers. It features a unique classification of the nonparametric analogs of their parametric counterparts according to the strength of the collected data. Applied Statistical Designs for the Researcher discusses three varieties of the Student t test, including a comparison of two different groups with different variances; two groups with the same variance; and a matched, paired group. It introduces the analysis of variance and Latin Square designs and presents screening approaches to comparing two factors and their interactions.

When an excessive proportion of the human energy requirement is derived from fat, the likelihood of obesity increases. Any such individual is at risk for diabetes and cardiovascular disease- grave and costly health hazards. The selective control of fat ingestion is a promising solution to these concerns. Existing data suggests that macronutrient intake can be manipulated. Further research is working to create pharmacological tools that will suppress fat consumption. It will also be possible to fight obesity, heart disease and diabetes. Neural and Metabolic Control of Macronutrient Intake systematically discusses the known physiological mechanisms involved in macronutrientselection, including their molecular, genetic and neurochemical aspects. The book is also a critical review of the hypothesis that ingestion of the three nutrients is regulated by separate neural control mechanisms, leaving open the possibility that strategies could be devised to intervene in bodily control systems and alter the proportion of fat in the diet. This reference provides three types of information: First, the basic background of the biochemical and physiological systems as they relate to macronutrient selection. Second, opinions and data concerning to what degree animals and humans show evidence of macronutrient selection. And, third, evidence about how the central nervous system might be involved in the choices animals make among macronutrients.

Research and study in biomechanics has grown dramatically in recent years, to the extent that students, researchers, and practitioners in biomechanics now outnumber those working in the underlying discipline of mechanics itself. Filling a void in the current literature on this specialized niche, Principles of Biomechanics provides readers with a solid grasp of the fundamentals and the enabling procedures of this rapidly expanding field, placing a sharp focus on dynamic phenomena in the area of whole-body biomechanics. Applies Biodynamic Models to Everyday Activities Emphasizing biodynamic modeling and the analysis of human body models, the book begins with a review of gross human anatomy and a summary of basic terminology. It describes various methods of analysis, including elementary mathematics, elementary mechanics, and the fundamental concepts of the mechanics of materials. Later chapters discuss the modeling of biosystems, tissue biomechanics, biodynamics, kinematics, kinetics, and the inertial properties of human body models. The book concludes with a review of sample applications of biodynamic models in activities such as lifting, maneuvering in space, walking, and swimming, as well as crash victim simulation. Uses simple language to convey complex principles With numerous professionals in a range of areas entering this field daily, there is a pressing need for a book which captures for a wide audience the principles of biomechanics analysis. Readily accessible to those with only a basic background in engineering fundamentals, mathematics, and physics, this text enables readers to understand virtually all areas of human body dynamics ranging from simple movements to optimal motions to accident victim dynamics.

This Second Edition is an essential guide to preparing for FDA pre-approval inspections-taking into account current trends in FDA expectations and inspection activities, such as the GMPs of the 21st Century, quality systems-based approach to inspections, risk-based inspections, quality by design, process analytical technology, design space, etc. The goal of this book is to help organizations gain rapid regulatory approval. Pharmaceutical Pre-Approval Inspections: A Guide to Regulatory Success, Second Edition: chronicles the major shifts in inspection activity as evidenced by a systems-based approach to inspections demonstrates what each area of pharmaceutical development, from research and development to training, is expected to provide to inspectors focuses on traditional development and submission activities, but also discusses cases where the transfer is from a domestic site to an international facility

A comprehensive source on mixed data analysis, Analysis of Mixed Data: Methods & Applications summarizes the fundamental developments in the field. Case studies are used extensively throughout the book to illustrate interesting applications from economics, medicine and health, marketing, and genetics. Carefully edited for smooth readability and seamless transitions between chapters All chapters follow a common structure, with an introduction and a concluding summary, and include illustrative examples from real-life case studies in developmental toxicology, economics, medicine and health, marketing, and genetics An introductory chapter provides a "wide angle" introductory overview and comprehensive survey of mixed data analysis Blending theory and methodology, this book illustrates concepts via data from different disciplines. Analysis of Mixed Data: Methods & Applications traces important developments, collates basic results, presents terminology and methodologies, and gives an overview of statistical research applications. It is a valuable resource to methodologically interested as well as subject matter-motivated researchers in many disciplines.

Many health professionals today seem to approach sports nutrition and physical activity recommendations with a "one size fits all" approach. Surprisingly, little consideration goes into addressing the changing needs of athletes as they progress in age. Nutrition and Exercise Concerns of Middle Age addresses the specific nutritional and physical activity needs of active individuals thirty to sixty years old. Judy A. Driskell, one of the world's leading experts in the field of sports nutrition, brings together cutting-edge research on the nutritional needs and exercise recommendations for this quickly growing age group. Internationally acclaimed experts on nutrition and kinesiology unveil their research in sports nutrition, endurance and strength training, age-related disorders, and nutrition and exercise recommendations of health organizations. They also explore the role of diet and physical activity in reducing the risk of and in treating age-related diseases such as cancer and cardiovascular disease. Nutrition and Exercise Concerns of Middle Age is a valuable resource for nutritionists, physicians, dieticians, and researchers looking to access authoritative information on exercise and sports nutrition recommendations for middle-age adults.

Lucidly Integrates Current Activities Focusing on both fundamentals and recent advances, Introduction to Machine Learning and Bioinformatics presents an informative and accessible account of the ways in which these two increasingly intertwined areas relate to each other. Examines Connections between Machine Learning & Bioinformatics The book begins with a brief historical overview of the technological developments in biology. It then describes the main problems in bioinformatics and the fundamental concepts and algorithms of machine learning. After forming this foundation, the authors explore how machine learning techniques apply to bioinformatics problems, such as electron density map interpretation, biclustering, DNA sequence analysis, and tumor classification. They also include exercises at the end of some chapters and offer supplementary materials on their website. Explores How Machine Learning Techniques Can Help Solve Bioinformatics Problems Shedding light on aspects of both machine learning and bioinformatics, this text shows how the innovative tools and techniques of machine learning help extract knowledge from the deluge of information produced by today's biological experiments.

Taking readers from the research laboratory to the bedside, this Second Edition compiles essential information on the pharmacodynamics of all major classes of the antimicrobial armamentarium including penicillins, cephalosposorins, cephamycins, carbapenems, monobactams, aminoglycosides, quinolones, macrolides, antifungals, antivirals, and emerging agents currently in development. Written by experienced professionals in the field, this guide uses an abundance of examples to depict methods to apply pharmacodynamic concepts to everyday clinical practice.

Once again the National Dairy Council has produced the industry reference on the important role of dairy foods in health. Packed with the latest information from the Council's notable scientists, the Handbook of Dairy Foods and Nutrition, Third Edition makes the case for the beneficial role of dairy foods in a variety of conditions and disease states. The handbook begins with a comprehensive overview of the nutritional content and benefits of milk and milk products including cheese and yogurt. The authors explain the effects of dairy intake on cardiovascular health and hypertension. The Dairy Council continues its research review by providing the most up-to-date information on the relationship between dairy intake and colon, breast, and prostate cancers. An entirely new chapter is devoted to addressing recent research about the role of dairy foods in weight management. Supporting the age-old advice that milk gives you strong bones and teeth, this handbook has chapters examining the evidentiary relationship between dairy intake and bone and dental health. A full chapter addresses the condition of lactose digestion, distinguishing lactose intolerance from lactose maldigestion, as well as providing research-based strategies to improve milk tolerance. A summary of dairy's contribution to health throughout the life cycle from childhood and adolescence into adulthood and old age, rounds out this latest installment of the Dairy Council's authoritative reference on the importance of dairy foods in the American diet. Continuing to provide state-of-the-art information on dairy products and nutrition, the Handbook of Dairy Foods and Nutrition, Third Edition is a useful resource for nutrition scientists, dietitians and other health professionals, educators, dairy researchers, and the food industry.

Although many books have been published on various aspects of human, animal, and plant parasitology, as well as the public health problems associated with parasites, none to date has offered a comprehensive glossary for those confronted with the discipline's exceptionally extensive terminology. To meet this need requires a dedicated text that can house the myriad entries that define all the basic principles and advanced nomenclature of parasitology. The Dictionary of Parasitology reflects current practice in all aspects of parasitology and includes spellings, punctuation, abbreviations, acronyms, symbols, nomenclature, prefixes, and suffixes. It covers the field of modern parasitology with concise, clear, and authoritative precision. The dictionary assigns entries of parasites to the primary divisions of parasitology: human, veterinary, plant, insect, or fish; although in many instances the area of interest may be wide-ranging. The dictionary provides the depth and breadth of knowledge that makes it both an informative and useful volume for beginners and experts in the field, as well as for writers and editors of scientific texts. Entries cover control measures, immunology, physiology, pharmacology, etc., and each are labeled according to the most appropriate area to which they relate. Attach tear sheet from text Providing more than 11,500 entries, the Dictionary of Parasitology, sets a standard that will allow those in the field to communicate with essential scientific accuracy.