In the post-genome era, questions concerning gene products, enzymes, and metabolism are returning to the forefront of life science research. Genetic information on its own does not fully account for an enzyme's kinetic and regulatory properties or for the behavior of the enzymes within its particular cellular milieu. Unanswered questions about the regulation, integration, and adaptation of metabolism have led to a resurgence of interest in protein, enzymological, and metabolic research for understanding biological processes.

Functional Metabolism: Regulation and Adaptation provides a comprehensive survey of metabolism. It includes an in-depth examination of the regulation of carbohydrates, lipids, and amino acids, and approaches to the study of enzyme regulation, signal transduction, and control of transcription and translation. The contributors-an internationally recognized group of researchers-also cover:

• The metabolic basis of diabetes, obesity, and blood disorders
• Oxidative stress and antioxidant defenses in health and disease
• Novel perspectives on biochemical adaptation to environmental stress
• Application of metabolic knowledge to developments in organ preservation and understanding the origin of life

From the basics of metabolic regulation and adaptation to the latest relevant advances in the genetic, proteomic, and enzymatic basis of how cells regulate their functions, Functional Metabolism: Regulation and Adaptation offers the most exhaustive treatment of the subject currently available. It is an essential text for students and practitioners in biochemistry, cell and molecular biology, and biomedicine.

"Personalist Bioethics" calls us to reflect on the intimate meaning of human existence and the social environment, going beyond any specific religious perspective and invoking human reason. It advances a metaphysics that is rationally grounded in philosophical anthropology and has a broad range of ethical applications for professors of bioethics, members of ethics committees, bioethics students, and those interested in the field in general, whether in medicine, law, or philosophy. Readers will find a presentation and discussion of the basic contours of personalist bioethics, comparisons of personalism with other philosophical positions, and ethical investigations of particular topics, ranging from genetic engineering to euthanasia. Translated by John A. Di Camillo and Michael J. Miller.

This book addresses various clinical and sub clinical applications of antioxidant nutraceuticals, with a primary focus on preventive use for general wellness, common ailments, and such chronic illnesses as cancer and neurological applications. This unique book captures the applications of natural antioxidants, which have been used for thousands of years in Traditional Chinese Medicine and Ayurvedic Medicine as well as modern nutraceuticals formulations. It covers antioxidant applications in clinical scenarios including the historical perspective, basic antioxidant properties and applications, anti-inflammatory properties, and antioxidant applications in a variety of clinical conditions.