This book (hardcover) is part of the TREDITION CLASSICS. It contains classical literature works from over two thousand years. Most of these titles have been out of print and off the bookstore shelves for decades. The book series is intended to preserve the cultural legacy and to promote the timeless works of classical literature. Readers of a TREDITION CLASSICS book support the mission to save many of the amazing works of world literature from oblivion. With this series, tredition intends to make thousands of international literature classics available in printed format again - worldwide.

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The volume covers the preparation and analysis of model systems for biological electron microscopy. The volume has chapters about prokaryotic as well as eukaryotic systems that are used as so-called model organisms in modern cell biology. These systems include the most popular systems, such as budding and fission yeast, the roundworm "C. elegans," the fly Drosophila, zebrafish, mouse, and Arabidopsis, but also organisms that are less frequently used in cell biology, such as "Chlamydomonas, Dictyostelium, Trypanosoma," faltworms, "Axolotl" and others. In addition, tissues and tissue culture systems are also covered. These systems are used for very diverse areas of cell biology, such as cell division, abscission, intracellular transport, cytoskeletal organization, tissue regeneration and others. Moreover, this issue presents the currently most important methods for the preparation of biological specimens. This volume, however, is not a classic EM methods book. The methods are not the main focus of this issue. The main goal here is to cover the methods in the context ofthe specific requirements of specimen preparation for each model organism or systems. This will be the first compendium covering the various aspects of sample preparation of very diverse biological systems.
Covers the preparation and analysis of model systems for biological electron microscopy. Includes the most popular systems but also organisms that are less frequently used in cell biology. This issue presents the currently most important methods for the preparation of biological specimens. This will be the first compendium covering the various aspects of sample preparation of very diverse biological systems."

Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.

This is a unique book on thyroid neoplasms in that it covers many current topics in the area including tumor development, tumor markers and preclinical treatment for advanced cancer as well as practical approaches (radioiodine, ultrasound, thyroglobulin monitoring and PET scanning). This book will give the general reader and specialist a good foundation for what is currently going on in the area of thyroid neoplasms.
*A translational approach to thyriod neoplasms
*Contributions from national experts in research and clinical medicine
*Current and practical approaches to patients with thyroid neoplasms

This book (hardcover) is part of the TREDITION CLASSICS. It contains classical literature works from over two thousand years. Most of these titles have been out of print and off the bookstore shelves for decades. The book series is intended to preserve the cultural legacy and to promote the timeless works of classical literature. Readers of a TREDITION CLASSICS book support the mission to save many of the amazing works of world literature from oblivion. With this series, tredition intends to make thousands of international literature classics available in printed format again - worldwide.

In "Science and the Religious Right," biophysicist John Jagger discusses false scientific and social positions of the Religious Right, including the ideas that the earth is only six thousand years old, evolution never occurred, and the United States was founded as a Christian nation. At best, such stances of the Religious Right have produced extensive political turmoil; they undermine true understanding of ourselves and the world we live in.

Many Americans know little science and are thus easily confused by such positions of religious fundamentalists. Jagger begins with a scientific primer for the intelligent and curious nonscientist, with simple explanations of such highly successful theories as relativity and evolution. He then discusses religion, explaining why many scientists become freethinkers after the models of Thomas Jefferson and Benjamin Franklin, who did not believe in a personal God. He shows that, while mainstream religion largely accepts modern science, the Religious Right holds anti-science and anti-intellectual ideas that have great social and political consequence-they want to replace teaching of evolution in our public schools with creationist ideas that are totally unsupported by science.

"Science and the Religious Right" shows why knowledge of some basic science, as well as of correct religious history, is essential for understanding false stances of the Religious Right that threaten American values and scientific truth.

Bioarchaeology is the analysis of human remains within an interpretative framework, including a wide range of contextual information. This comprehensive and much-needed manual provides both a starting point and a reference for archaeologists working in this integrative field. The authors cover a range of bioarchaeological methods and theory including: * Ethical issues involved in dealing with human remains, specifically related to NAGPRA * Field and taphonomic clues * Lab and Forensic techniques * Best practices methods for Excavation techniques * Special applications of Bioarchaeology * Theoretical frameworks of Bioarchaeology With case studies from over twenty years each of bioarchaeological research, the authors integrate theoretical and methodological discussion with a wide range of field studies, from different geographic areas, time periods, and data types, to demonstrate the full scope of this important field of study.

This book is devoted to the rapidly growing area of science dealing with structure and properties of biological surfaces in their relation to particular function(s). This volume, written by a team of specialists from different disciplines, covers various surface functions such as protection, defense, water transport, anti-wetting, self cleaning, light reflection and scattering, and acoustics. Because biological surfaces have a virtually endless potential of technological ideas for the development of new materials and systems, inspirations from biology could also be interesting for a broad range of topics in surface engineering.

Designed for a one or two semester senior undergraduate or graduate bioinformatics course, "Statistical Bioinformatics" takes a broad view of the subject - not just gene expression and sequence analysis, but a careful balance of statistical theory in the context of bioinformatics applications. The inclusion of R code as well as the development of advanced methodology such as Bayesian and Markov models provides students with the important foundation needed to conduct bioinformatics.

Ancillary list: * Online ISM- http: //textbooks.elsevier.com/web/manuals.aspx?isbn=9780123751041 * Companion Website w/ R code and Ebook- http: //textbooks.elsevier.com/web/manuals.aspx?isbn=9780123751041 * Powerpoint slides- http: //textbooks.elsevier.com/web/Manuals.aspx?isbn=9780123751041
Integrates biological, statistical and computational conceptsInclusion of R & SAS codeProvides coverage of complex statistical methods in context with applications in bioinformaticsExercises and examples aid teaching and learning presented at the right levelBayesian methods and the modern multiple testing principles in one convenient book"

The purpose of this book is to convey to the worldwide scientific community the rapid and enthusiastic progress of state-of-the-art quantum chemistry. Quantum chemistry continues to grow with remarkable success particularly due to rapid progress in supercomputers. The usefulness of quantum chemistry is almost limitless. Its application covers not only physical chemistry but also organic and inorganic chemistry, physics, and life sciences. This book deals with all of these topics. Frontiers of Quantum Chemistry is closely related to the symposium of the same name held at Kwansei Gakuin University at Nishinomiya, Japan, in November 2015. The book's contributors, however, include not only invited speakers at the symposium but also many other distinguished scientists from wide areas of quantum chemistry around the world.

Oxidants, like other aspects of life, involves tradeoffs. Oxidants, whether intentionally produced or by-products of normal metabolism can either mediate a variety of critical biological processes but when present inappropriately cause extensive damage to biological molecules (DNA, proteins, and lipids). These effects can lead to either damage that is a major contributor to aging and degenerative diseases (or to other diseases such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts) or normal physiological function- tissue repair, defense against pathogens and cellular proliferation. On the other hand the body is equipped with a complex antioxidant/oxidant handling system which includes both enzymatic and nonenzymatic (i.e. small molecules such as flavonoids, ascorbate, tocopherol, and carotenoids) produced endogenously or derived from the diet. This book focuses on how the same molecules can have favorable or noxious effects depending on location, level and timing.

Each chapter focuses on one particular molecule or oxidant/antioxidant system and provides a state of the art review of the current understanding regarding both positive and negative actions of the system under review.

Teaches Students How to Perform Spatio-Temporal Analyses within Epidemiological Studies Spatio-Temporal Methods in Environmental Epidemiology is the first book of its kind to specifically address the interface between environmental epidemiology and spatio-temporal modeling. In response to the growing need for collaboration between statisticians and environmental epidemiologists, the book links recent developments in spatio-temporal methodology with epidemiological applications. Drawing on real-life problems, it provides the necessary tools to exploit advances in methodology when assessing the health risks associated with environmental hazards. The book's clear guidelines enable the implementation of the methodology and estimation of risks in practice. Designed for graduate students in both epidemiology and statistics, the text covers a wide range of topics, from an introduction to epidemiological principles and the foundations of spatio-temporal modeling to new research directions. It describes traditional and Bayesian approaches and presents the theory of spatial, temporal, and spatio-temporal modeling in the context of its application to environmental epidemiology. The text includes practical examples together with embedded R code, details of specific R packages, and the use of other software, such as WinBUGS/OpenBUGS and integrated nested Laplace approximations (INLA). A supplementary website provides additional code, data, examples, exercises, lab projects, and more. Representing a major new direction in environmental epidemiology, this book-in full color throughout-underscores the increasing need to consider dependencies in both space and time when modeling epidemiological data. Students will learn how to identify and model patterns in spatio-temporal data as well as exploit dependencies over space and time to reduce bias and inefficiency.

"Personalist Bioethics" calls us to reflect on the intimate meaning of human existence and the social environment, going beyond any specific religious perspective and invoking human reason. It advances a metaphysics that is rationally grounded in philosophical anthropology and has a broad range of ethical applications for professors of bioethics, members of ethics committees, bioethics students, and those interested in the field in general, whether in medicine, law, or philosophy. Readers will find a presentation and discussion of the basic contours of personalist bioethics, comparisons of personalism with other philosophical positions, and ethical investigations of particular topics, ranging from genetic engineering to euthanasia. Translated by John A. Di Camillo and Michael J. Miller.

Health sciences librarianship today demands a balance among computer files, human ingenuity, and print sources. The many information sources presently available enable health sciences librarians to do a better job, but that job has also become correspondingly more difficult. This professional reference surveys the various types of print and electronic resources important to the health sciences and provides valuable practical advice to librarians for meeting the information needs of researchers, practicing physicians, and other health professionals. Health sciences librarianship today demands a balance among electronic files, human ingenuity, and print sources. Thanks to computerization and telecommunications, librarians can do much more now than just a few years ago. While the tremendous growth in available resources has enabled librarians to provide more thorough information to patrons, the process of doing so has become correspondingly more complex. While librarians still need to use many traditional skills, they must also develop new ways of finding and utilizing information. This professional reference surveys the field of health sciences librarianship and provides extensive practical advice to assist health sciences librarians in meeting the information needs of their patrons. Because journal literature is the principal medium of information in the health sciences, the book begins with an examination of the roles that journals play as well as the large proportion of the library budget that they consume. The volume then discusses techniques of searching journal literature, such as print and electronic indexing and abstracting tools. Additional chapters are devoted to the selection and organization of health sciences books, and reference tools and services. Special attention is given to the electronic distribution of biomedical information. With important sources of health information now becoming available via the Internet, this book provides a point of departure to evaluate those sources. The final chapter discusses the various environments that shape health sciences librarianship, such as library settings, professional associations, and economic contexts.

Contemporaries of the modest and unassuming scientist Joseph Leidy (1823-91) revered him as the supreme consultant in questions relating to human anatomy, paleontology, protozoology, parasitology, anthropology, mineralogy, botany, and numerous other scientific fields. Leidy's achievements and the breadth of his scientific interests and knowledge were astonishing. He seemed, in short, to be the man who knew everything. This is the first published biography of the remarkable Joseph Leidy-a leading American scientist of the mid-nineteenth century, the foremost human anatomist of his time, the first truly productive microscopist, the author of numerous groundbreaking scientific papers and books, and a devoted professor at the University of Pennsylvania and Swarthmore College. An unflagging pioneer and an exceptional illustrator, Leidy was the first in America to use the microscope as a tool in forensic medicine. He established the concept of parasitism in America. He was also the father of American protozoology and parasitology, describing for the first time Trichina in the pig, the source of the human disease trichinosis. As the founder of American vertebrate paleontology, he was the first to describe a dinosaur and many other extinct animals in America. Leonard Warren provides a full account of Leidy's life and accomplishments and sets them in the social and historical context of Philadelphia and the United States in Leidy's day. Warren also explores the reasons for the puzzling disparity between Leidy's fame and recognition during his life and virtual anonymity a century after his death.