Transcendental phenomenology presumed to have overcome the classic mind-body dichotomy in terms of consciousness, yet, according to progress in scientific studies, the biological functions of the brain seem to appropriate significant functions attributed traditionally to consciousness. Should we indeed dissolve the specificity of human consciousness by explaining human experience in its multiple sense-giving modalities through the physiological functions of the brain? The present collection of studies addresses this crucial question challenging such "naturalizing" reductionism from multiple angles. In search for the roots of "The Specifically Human Experience" (Bombala), moving along the line of "Animality and Intellection"(Gosetti-Ferencei), "Naturalistic Attitude and Personalistic Attitude"(Villela-Petit), and numerous other perspectives, we arrive at a novel proposal to explain the scholar functional differentiation of conscious modalities. We reach their source in the ontopoietic thread conducting the Logos of Life in its stepwise "Evolutive Unfolding"(Carmen Cozma), and in "sentience" as its quintessential core of further irreducible continuity (Tymieniecka) dispelling dichotomies and reductionisms.

Papers by:
Grahame Lock, Anna-Teresa Tymieniecka, Daniela Verducci, Ted Toadvine, Mary Trachsel, Martin Holt, Mary Jeanne Larrabee, Leszek Pyra, Bronislaw Bombala, Konrad Rokstad, Ilja Maso, Nancy Mardas, Jennifer Anna Gosetti-Ferencei, Maria Villela-Petit, Mara Stafecka, Carmen Cozma, Francesco Totaro, Andreas Brenner, Sinan Kadir Celik, Osvaldo Rossi, Maria Manuela Brinto Martins, Elga Freiberga, Klymet Selvi, J.C. Couciero-Bueno, Patricia Trutty-Coohill, Walter Lammi, Ljudmila Molodkina, Martin Nkafu Nkemnkia.

This text should be a useful guide for researchers in immunology, cell and molecular biology and development biology.

Based on material delivered at several summer schools, this book is the first comprehensive textbook at the graduate level encompassing all aspects associated with the emerging field of astrobiology.

Volume II gathers another set of extensive lectures covering topics so diverse as the formation and the distribution of elements in the universe, the concept of habitability from both the planetologists' and the biologists' point of view and artificial life. The contributions are held together by the common goal to understand better the origin of life, its evolution and possible existence outside the Earth's realm.
The volume ends with 120 pages of a very useful appendix comprising "Some Astrophysical Reminders," "Useful Astrobiological Data" and "An Astrobiological Glossary."

Philosophy of Biology is a rapidly expanding field. It is concerned with explanatory concepts in evolution, genetics, and ecology. This collection of 25 essays by leading researchers provides an overview of the state of the field. These essays are wholly new; none of them could have been written even ten years ago. They demonstrate how philosophical analysis has been able to contribute to sometimes contested areas of scientific theory making.
-Written by internationally acknowledged leaders in the field
- Entries make original contributions as well as summarizing state of the art discoveries in the field
- Easy to read and understand

This book (hardcover) is part of the TREDITION CLASSICS. It contains classical literature works from over two thousand years. Most of these titles have been out of print and off the bookstore shelves for decades. The book series is intended to preserve the cultural legacy and to promote the timeless works of classical literature. Readers of a TREDITION CLASSICS book support the mission to save many of the amazing works of world literature from oblivion. With this series, tredition intends to make thousands of international literature classics available in printed format again - worldwide.

Scent and Chemistry Odor impressions have cast a spell over mankind since the dim and distant past. But even today, we are -consciously or subconsciously- guided by our sense of smell and the chemistry behind it. The prominent fragrance chemists Gunther Ohloff, Wilhelm Pickenhagen and Philip Kraft convey the scientist, the perfumer, and the interested layman with a vivid and up-to-date picture of the chemistry of odorants and the research in odor perception. In this second thoroughly revised and updated edition they are joined by creative perfumer Fanny Grau, a rising master in this metier, who complements the scientific treatise by a concise introduction to the art of perfumery and its composition techniques. Besides this new chapter on the creative aspects of perfumery, the book details on the molecular basis of olfaction, olfactory characterization of perfumery materials, structure-odor relationships, the chemical synthesis of odorants, and the chemistry of essential oils and odorants from the animal kingdom, backed up by many perfume examples and historical aspects. It will serve as a thorough introductory text for everyone interested in the molecular world of odors.

This book covers a wide range of recent statistical methods that are of interest to scientists in biostatistics as well as in other related fields such as chemometrics, environmetrics and geophysics. The contributed papers, from internationally recognized researchers, present various statistical methodologies together with a selected scope of their main mathematical properties and their application in a real case study.

Purposefully designed as a resource for practicing and student toxicologists, Statistics and Experimental Design for Toxicologists and Pharmacologists, Fourth Edition equips you for the regular statistical analysis of experimental data. Starting with the assumption of basic mathematical skills and knowledge, the author supplies a complete and systematic yet practical introduction to the statistical methodologists available for, and used in, the discipline. For every technique presented, a worked example from toxicology is also presented. See what's new in the Fourth Edition: -The first practical guide to performing meta analysis allowing for using the power inherent in multiple similar studies -Coverage of Bayesian analysis and data analysis in pharmacology and toxicology -Almost 200 problems with solutions -Discussion of analysis of receptor binding assays, safety pharmacology assays and other standard types conducted in pharmacology -A new chapter explaining the basics of Good Laboratory Practices (GLPs) -For those with computer skills, this edition has been enhanced with the addition of basic SAS Written specifically for toxicologists and pharmacologists, the author draws on more than 30 years of experience to provide understanding of the philosophical underpinnings for the overall structure of analysis. The book's organization fosters the ordered development of skills and yet still facilitates ease of access to information as needed. This Fourth Edition gives you the tools necessary to perform rigorous and critical analysis of experimental data and the insight to know when to use them.

This volume is an interdisciplinary book which introduces, in a very readable way, state-of-the-art research in the fundamental topics of mathematical modelling of Biosystems. In short, the book offers an overview of mathematical and computational modelling of biosystems including biological phenomena in general. There is also a special introduction to Protein Physics which aims to explain the all-or-none first order phase transitions from native to denatured states.

The book deals with the role of both oxygen- and nitrogen-centred free radicals in inflammatory diseases such as rheumatoid arthritis. The well-known involvement of the superoxide anion radical in the bactericidal action of inflammatory cells suggests that radicals and the inflammatory response are inextricably linked. The widespread involvement of radicals in human disease seems inevitable, because inflammation is such a conspicuous component of human disease. For the first time, the present text integrates contributions from leading research groups who have been investigating the role of radicals within the context of all stages of inflammtion, such as the recruitment of inflammatory cells, their bactericidal action, inflammatory tissue destruction and inflammatory cell death by apoptosis. The chapters are broadly organised so that they trace the clinical course of the acute and chronic inflammtory response, emphasising the therapeutic implications of recent data on the contribution of nitric oxide and related nitrogen-centred species. The book will be of interest to academic and industrial researchers and clinicians with interests in the fields of inflammation or free radical biology.

Volume 3 takes the subject of better land husbandry further. The book first points out the sort of things which have been, and are being used, but are failing to deliver what is required. It then explains the causes of erosion, the theory and practice of soil and water conservation, and practical and lasting ways to construct terraces, including such details as how to build different kinds of terrace walls. Nothing grows from the top down, as also with soil improvement. It explains in detail the way of achieving practical and sustainable soil and water conservation, practical ways in which farmers can themselves make and use practical and lasting ways to construct terraces, including such details as how to build different kinds of terrace walls.

T Cell Antigen and MHC Recognition; B. Boitel, et al. Structure of the TCR-Ag-MHC Complex; N. Gervois, et al. Positive and Negative Selection of T Cells; H. von Boehmer. Peripheral Tolerence; D.C. Parker. On the Antigenicity of Antibody Idiotypes; K. Hannestad. A Network of Self Interactions; M. Zanetti. Cloned Suppressor T Cells; T. Tada, et al. The Autoreactive T Cell Receptor; E. Heber-Katz. The Relationship Between Diabetes and Lymphopenia in the BB Rat; S. Joseph, et al. Immunosuppression by MHC Class II Blockade; L. Adorini. Recognition of HIV Antigens by Human T Helper Cells; F. Manca, et al. Proliferative Responses to the V3 Region of HIV Envelope Are Enhanced Following Immunization with V3; S.J. Harris, et al. Teaching Immunology; F. Celada, P.E. Seiden. Biospecific Monoclonal Antibody-Targeted Cytotoxic T Lymphocytes Can Recycle; J.A.C. Voorthuis, et al. 13 additional articles. Index.

What is the actual basis of terms such as "goal," "function," and "for the sake of"? Can these teleological concepts be validly applied to non-conscious biological processes such as the heartbeat, plant growth, and cellular metabolism? Does the behavior of any inanimate objects, natural or man-made, qualify as goal-directed? To resolve these issues, Harry Binswanger provides a unique approach combining factual and epistemological considerations. If human purposeful action is the paradigm case of goal-directed action, then regarding a non-purposeful process as goal-directed means taking it to be causally similar to purposeful action. Accordingly, to determine the proper extent of teleological concepts, Binswanger provides an analysis of purposeful action and a point-by-point comparison of the features of purposeful action to those of vegetative and inanimate processes. He concludes that natural selection, in adapting actions to ends with survival value, does make all living action qualify as goal-directed, and that no inanimate process qualifies. An appendix compares Binswanger's views with those of Larry Wright and Andrew Woodfield.

Pattern Formation in Morphogenesis is a rich source of interesting and challenging mathematical problems. The volume aims at showing how a combination of new discoveries in developmental biology and associated modelling and computational techniques has stimulated or may stimulate relevant advances in the field. Finally it aims at facilitating the process of unfolding a mutual recognition between Biologists and Mathematicians of their complementary skills, to the point where the resulting synergy generates new and novel discoveries. It offers an interdisciplinary interaction space between biologists from embryology, genetics and molecular biology who present their own work in the perspective of the advancement of their specific fields, and mathematicians who propose solutions based on the knowledge grasped from biologists.

This 2nd edition begins with an overview of NMR development and applications in biological systems. It describes recent developments in instrument hardware and methodology. Chapters highlight the scope and limitation of NMR methods. While detailed math and quantum mechanics dealing with NMR theory have been addressed in several well-known NMR volumes, chapter two of this volume illustrates the fundamental principles and concepts of NMR spectroscopy in a more descriptive manner. Topics such as instrument setup, data acquisition, and data processing using a variety of offline software are discussed. Chapters further discuss several routine stategies for preparing samples, especially for macromolecules and complexes. The target market for such a volume includes researchers in the field of biochemistry, chemistry, structural biology and biophysics.