Increasing scientific evidence suggests that the majority of diseases including cancer are driven by oxidative stress and inflammation, attributed to environmental factors. These factors either drive genetic mutations or epigenetically modify expression of key regulatory genes. These changes can occur as early as gestational fetal development, and major questions remain as to how dietary/nutritional phytochemical factors biochemically interact with such genetic and epigenetic events. With chapters written by international experts, Inflammation, Oxidative Stress, and Cancer: Dietary Approaches for Cancer Prevention examines the latest developments on the effects of various dietary phytochemicals. Divided into nine sections, the book begins with the basic mechanisms of inflammation/oxidative stress-driven cancer, including an overview of the topic and how to prevent carcinogenesis, the role of obesity in inflammation and cancer, and antioxidant properties of some common dietary phytochemicals. Subsequent sections cover cellular signal transduction, molecular targets, and biomarkers of dietary cancer-preventive phytochemicals, as well as their potential challenges with in vivo absorption and pharmacokinetics. The chapters also examine the cancer-preventive properties of various classes of phytochemicals, including vitamins A, D, and E; omega-3 and omega-6 fatty acids; flavanoids and polyphenols; garlic organosulfur compounds and cruciferous glucosinolates; and selenium, traditional Chinese herbal medicines, and alpha lipoic acid. The final section of the book explores the latest developments on the interactions of dietary phytochemicals through epigenetics and the management of chronic inflammation with nutritional phytochemicals.

The utilization of footwear impression evidence continues to evolve with new materials, equipment and techniques, providing an increased ability to detect, record, enhance, and examine this form of evidence. Recently developed technology now allows investigators to more efficiently or, in some cases, instantly link multiple crime scenes where impressions have been produced by the same perpetrator. Forensic Footwear Evidence covers a wide range of relevant topics, including historical references, general information about the formation and investigative use of footwear impressions, and the best practices and considerations that apply to the recovery, enhancement, and examination of this evidence. Drawing on the author's 44 years of acquired knowledge and experience, it is the most comprehensive and authoritative text published to date on this topic. Highlighted topics covered within the book include Three chapters covering footwear manufacturing Shoe grading, sizing, and the forensic application of sizing information Examination and reporting procedures Casting impressions in snow Barefoot evidence Topics of interest for both prosecution and defense attorneys The book includes more than 300 color photographs and illustrations throughout, as well as case examples that apply theoretical concepts to the real world. A single, complete reference on the subject, Forensic Footwear Evidence presents a wide range wealth of information that will serve as an invaluable reference to novice and experienced examiners, crime scene technicians, investigators, and prosecution and defense counselors alike.

The must-have ten-volume successor to the critically acclaimed Nanotechnologies for the Life Sciences series, "Nanomaterials for the Life Sciences, 10 Volume Set" provides an excellent, in-depth overview of all nanomaterial types and their uses in the life sciences. Each volume is dedicated to a specific material class and covers fundamentals, synthesis strategies, structure-property relationships, material behavior fine-tuning, biological effects, and applications in the life sciences. This landmark set provides materials scientists, chemists, biologists, molecular biologists, clinical physicists, physiological chemists, medicinal chemists, and toxicologists with essential awareness of life science applications.

This revised and updated second edition is an accessible companion designed to help science and technology students develop the knowledge, skills and strategies needed to produce clear and coherent academic writing in their university assignments. Using authentic texts to explore the nature of scientific writing, the book covers key areas such as scientific style, effective sentence and paragraph structure, and coherence in texts and arguments. Throughout the book, a range of tasks offers the opportunity to put theory into practice. The explorative tasks allow you to see how language works in a real scientific context, practice and review tasks consolidate learning and help you to develop your own writing skills, and reflective tasks encourage you to think about your own knowledge and experience, and bring this to bear on your own writing journey at university. Key features of the new edition include: * Updated content and additional tasks throughout * New chapters, covering writing in the sciences and writing at university * The introduction of reflective tasks * Up-to-date examples of authentic scientific writing Clear, engaging and easy-to-use, this is an invaluable tool for the busy science or technology student looking to improve their writing and reach their full academic potential.

The pace and sophistication of advances in medicine in the past two decades have necessitated a growing need for a comprehensive reference that highlights current issues in medicine. Each volume in the Current Issues in Medicine series is a stand-alone text that provides a broad survey of various critical topics-all accomplished in a user-friendly yet interconnected format. The series not only highlights current advances but also explores related topics such as translational medicine, regulatory science, neglected diseases, global pandemics, patent law, immunotoxicology, theranostics, big data, artificial intelligence, novel imaging tools, combination drug products, and novel therapies. While bridging the gap between basic research and clinical medicine, this series provides a thorough understanding of medicine's potential to address health problems from both the patient's and the provider's perspectives in a healthcare setting. The range of topics covered and the expertise of the contributing authors accurately reflect the rapidly evolving areas within medicine-from basic medical sciences to clinical specialties. Each volume is essential reading for physicians, medical students, nurses, fellows, residents, undergraduate and graduate students, educators, policymakers, and biomedical researchers. The multidisciplinary approach of the series makes it a valuable reference resource for the pharmaceutical industry, academia, and governments. However, unlike other series on medicine or medical textbooks, this series focuses on current trends, perspectives, and issues in medicine that are central to healthcare delivery in the 21st century. Volume 1 focuses on the current issues in basic medical sciences, subjects that are fundamental to the practice of medicine. Specifically, it covers medical biochemistry, genomics, physiology, and pathology. These subjects, traditionally taught in the first two years of medical school that precede clinical instruction, provide a core of basic knowledge critical to the success in clinical medicine during rotations, training, and medical practice.

The pace and sophistication of advances in medicine in the past two decades have necessitated a growing need for a comprehensive reference that highlights current issues in medicine. Each volume in the Current Issues in Medicine series is a stand-alone text that provides a broad survey of various critical topics-all accomplished in a user-friendly yet interconnected format. The series not only highlights current advances but also explores related topics such as translational medicine, regulatory science, neglected diseases, global pandemics, patent law, immunotoxicology, theranostics, big data, artificial intelligence, novel imaging tools, combination drug products, and novel therapies. While bridging the gap between basic research and clinical medicine, this series provides a thorough understanding of medicine's potential to address health problems from both the patient's and the provider's perspectives in a healthcare setting. The range of topics covered and the expertise of the contributing authors accurately reflect the rapidly evolving areas within medicine-from basic medical sciences to clinical specialties. Each volume is essential reading for physicians, medical students, nurses, fellows, residents, undergraduate and graduate students, educators, policymakers, and biomedical researchers. The multidisciplinary approach of the series makes it a valuable reference resource for the pharmaceutical industry, academia, and governments. However, unlike other series on medicine or medical textbooks, this series focuses on current trends, perspectives, and issues in medicine that are central to healthcare delivery in the 21st century. Volume 2 focuses on the current issues in basic medical sciences, subjects that are fundamental to the practice of medicine. Specifically, it discusses clinical immunology, medical microbiology, COVID-19, and big data. These subjects, traditionally taught in the first two years of medical school that precede clinical instruction, provide a core of basic knowledge critical to the success in clinical medicine during rotations, training, and medical practice.

Reflecting the advances made in recent years, this is a comprehensive overview of calcium orthophosphates for bioceramics and biocomposites with a special focus on the detailed description of all those available, including their biological and geological occurrence, preparation, chemical composition, structure-property relationships and applications. In particular, the book discusses the suitability of these orthophosphates for biomedical applications and their use as bone grafts in surgery and medicine. The result is a useful reference for researchers with an academic, medical or commercial background.

Teaches Students How to Perform Spatio-Temporal Analyses within Epidemiological Studies Spatio-Temporal Methods in Environmental Epidemiology is the first book of its kind to specifically address the interface between environmental epidemiology and spatio-temporal modeling. In response to the growing need for collaboration between statisticians and environmental epidemiologists, the book links recent developments in spatio-temporal methodology with epidemiological applications. Drawing on real-life problems, it provides the necessary tools to exploit advances in methodology when assessing the health risks associated with environmental hazards. The book's clear guidelines enable the implementation of the methodology and estimation of risks in practice. Designed for graduate students in both epidemiology and statistics, the text covers a wide range of topics, from an introduction to epidemiological principles and the foundations of spatio-temporal modeling to new research directions. It describes traditional and Bayesian approaches and presents the theory of spatial, temporal, and spatio-temporal modeling in the context of its application to environmental epidemiology. The text includes practical examples together with embedded R code, details of specific R packages, and the use of other software, such as WinBUGS/OpenBUGS and integrated nested Laplace approximations (INLA). A supplementary website provides additional code, data, examples, exercises, lab projects, and more. Representing a major new direction in environmental epidemiology, this book-in full color throughout-underscores the increasing need to consider dependencies in both space and time when modeling epidemiological data. Students will learn how to identify and model patterns in spatio-temporal data as well as exploit dependencies over space and time to reduce bias and inefficiency.

Police success in linking vehicles to the scene of a crime through the impressions and tracks those vehicles leave behind has long served as a successful and reliable forensic tool. The collection and forensic evaluation of that evidence, however, requires specialized knowledge, training, and expertise. Drawing from the author's 34 years of experience, first as an FBI examiner and currently as a private consultant in the area of tire evidence, Tire and Tire Track Evidence: Recovery and Forensic Examination is the most comprehensive and up-to-date volume available on the subject. Covering all aspects of the field, the book begins with general information on the modern pneumatic tire and basic terminology. For both the crime scene technician and the forensic examiner, the author addresses information on both how to recover tire track evidence and how to photograph and cast the individual tread detail from those impressions. The book explains and illustrates the necessary information on obtaining known exemplars; tire manufacturing, and retreading tires. It explains important aspects of tires including their tread design and dimension, noise treatment, general wear and individual acquired characteristics. The author instructs on applying that knowledge while conducting a structured examination procedure, resulting in the final evaluation of evidence and report writing as well as the presentation of tire evidence in court. He provides information on databases and resources along with case examples, including the Oklahoma City bombing. Informative and useful, this book gives crime scene technicians and forensic examiners the tools to accurately and reliably collect, recover, and examine tire evidence.

Our future is closely tied to that of the variety of life on Earth, and yet there is no greater threat to it than us. From population explosions and habitat destruction to climate change and mass extinctions, John Spicer explores the causes and consequences of our biodiversity crisis. In this revised and updated edition, he examines how grave the situation has become over the past decade and outlines what we must do now to protect and preserve not just nature’s wonders but the essential services that biodiversity provides for us, seemingly for nothing.

This new edition bridges the gap between its predecessor, which emphasized conventional methods, and subsequent advances in analytical methodologies. Researchers and analysts strive to keep up with advances in microbiological methods. Although many techniques appear regularly in scientific literature, only a few of these are used routinely by analysts and even fewer are useable in teaching laboratories. In the time since the publication of the first edition, the authors of this book have screened many new published analytical methods for suitability as laboratory exercises. The new edition not only implements new and advanced analytical methods, but also improves currently used techniques. Since publication of the first edition, new selective and highly differential media have become available commercially. Some of the previous laboratory exercises included rapid detection kits that are no longer available from the manufacturer. Basic concepts have been modified to better reflect emerging food safety concerns. In the new laboratory manual, these issues are addressed in a creative manner.

First published in 2007. Routledge is an imprint of Taylor & Francis, an informa company.

First published in 2003. Routledge is an imprint of Taylor & Francis, an informa company.

Exam Board: OCR Level: A-Level Subject: Biology First Teaching: September 2015 First Exam: Summer 2016 Our Student Workbooks build students' understanding, developing the confidence and exam skills they need, whilst providing ready prepared lesson solutions. - Reinforce and apply topic understanding as classwork or extension tasks, or with revision - Prepare students to meet the demands of the new specification by practising exam technique - Create opportunities for independent learning and self-assessment with answers online - Supplement key resources such as textbooks - Time-saving and economical lesson solutions for both specialist and non-specialist teachers

This book summarizes, discusses, and speculates on the essential lipid nutrients required by insects. It examines various ways in which insects convert diverse food-plant sterols into the major insect tissue sterols and how the insect sterols are metabolized into the ecdysone moulting hormones.

Data Warehousing for Biomedical Informatics is a step-by-step how-to guide for designing and building an enterprise-wide data warehouse across a biomedical or healthcare institution, using a four-iteration lifecycle and standardized design pattern. It enables you to quickly implement a fully-scalable generic data architecture that supports your organization's clinical, operational, administrative, financial, and research data. By following the guidelines in this book, you will be able to successfully progress through the Alpha, Beta, and Gamma versions, plus fully implement your first production release in about a year. The Alpha version allows you to implement just enough of the basic design pattern to illustrate its core capabilities while loading a small sampling of limited data for demonstration purposes. This provides an easy way for everyone involved to visualize the new warehouse paradigm by actually examining a core subset of the working system. You can finish the Alpha version, also referred to as the proof-of-concept, in as little as 3-4 weeks. The Beta version, which can be completed in about 2-3 months, adds required functionality and much more data. It allows you to get the full warehouse up and running quickly, in order to facilitate longer-term planning, user and support team training, and setup of the operational environment. The Gamma version, which is a fully-functional system-though still lacking data-can be implemented in about 3-4 months. About one year after starting, you will be ready to launch Release 1.0 as a complete and secure data warehouse.

In this title, first published in 1984, Peter Morton argues that in late Victorian Britain a group of novelists and essayists quite consciously sought and found ideas in post-Darwinian biology that were susceptible to imaginative transformation. The period between 1860 and 1900 was a time of great confusion in biology; the natural selection hypothesis was in retreat before its acute critics, and no extension of evolutionary theory to human affairs was too bizarre to attract its quota of enthusiasts. Writers capitalised on this prevailing uncertainty and used it to their own artistic or polemic ends. A fascinating and interdisciplinary title, this reissue will interest students of late Victorian literature, as well as historians of biological theory between The Origin of Species and Mendel.

-- Finishing and publishing a PhD is daunting as, for most students, it will be their first experience working within the academic system. This guide offers a helping hand during and when making decisions about how to move on with their career, specifically in the biological sciences. -- Examples are tailored to biological science, offering a unique reference for PhD students in these disciplines. -- The author has authored more than 200 peer reviewed scientific papers and book chapters, and five books. He has been the Editor-in-Chief of an ISI journal for 9 years, and has graduated more than 20 postgraduate students. His blog on writing and publishing in biological sciences is read by thousands globally. -- Most of the 25,000 universities in the world have postgraduates in biological sciences, and emerging economies, such as India and China, will have special interest in this book as their academic systems still fall outside of the academic mainstream. -- The book has many short, easy to read, chapters which are interconnected to provide a comprehensive treatment of each subject, and it explore the 'hot' topics in academic publishing, from Open Access to new blockchain models, as well as academic bullying.

There are over 400 CHD risk factors that need to be evaluated, prevented, and treated. It is crucial that we have tests for early identification, prevention and treatment of CHD and MI. CHD remains the number one cause of morbidity and mortality in the United States. This book discusses not only older traditional risk factors of heart disease, but new considerations including updated genetic material which is state of the art. This book provides a new and detailed explanation of the causes of CHD and MI based on genetics, blood tests, urine tests. vascular tests and cardiac tests. Once this information is understood and applied to the patient the control of CHD risk factors, cardiovascular complications such as MI and heart failure will be improved with fewer adverse effects and lower cost. No other heart book on the market has this updated and extensive data based on published trials and the experience of the author. Chapters are written in an easy- to -understand format and all medical terms are defined for the reader. Tables and figures are provided each chapter to better illustrate what is described in the text, provide concise, understandable, and valuable information. All references are numbered in the text and then listed at the end of each chapter - the references provide additional medical information. Summaries and Key Take Away Points are provided at the end of each chapter. A sources section is listed at the end of the book which lists contact information for the best nutritional supplement companies, lab, and testing companies, as well as other important sources mentioned in the text of the book.

This informative new book takes an interdisciplinary look at agricultural and food production and how new engineering practices can be used to enhance production. With contributions from international experts from India, Russia, China, Serbia, and USA, this book presents a selection of chapters on some of these emerging practices, focusing on soil and water conservation and management; agricultural processing engineering; water quality and management; emerging agricultural crops; renewable energy use in agriculture; and applications of nanotechnology in agriculture.

This new volume, Herbal Product Development: Formulation and Applications, addresses some of the challenges that hinder the path of successful natural products from laboratory to market. Highly skilled, experienced, and renowned scientists and researchers from around the globe offer up-to-date information that describes characteristics of herbs and herbal products, applications, evaluation techniques, and more. There is also a section dedicated to alternative medicinal strategies for the treatment and cure of diverse diseases. Also considered, of course, is the efficacy and safety of herbal products, which are of major concern. This valuable volume will be an important addition to the library of those involved in herbal product development and testing, including researchers, scientists, academicians, industry professionals, and students in this area.

This book represents a collection of papers on the subject of the creation of desert-like conditions as a result of human or natural causes. It provides considerable reference material for those interested in pursuing the various subtopics in greater depth.

Covers micro- and Nano- technologies approaches with current trends with safety and efficacy in product development. Presents overview of recent progress of stability testing, reverse engineering, validation and regulatory perspectives as per regulatory requirements. Provides comprehensive overview of latest research related to the micro and nanotechnological including designing, optimization, validation, scale of micro and nanotechnologies. This book is edited by the two-well known researchers by contribution of the vivid chapters from renowned scientists across the globe in field of pharmaceutical sciences.