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Books > Science & Mathematics > Biology, life sciences > General

Neural and Metabolic Control of Macronutrient Intake (Paperback): Hans-Rudolf Berthoud, Randy J. Seeley Neural and Metabolic Control of Macronutrient Intake (Paperback)
Hans-Rudolf Berthoud, Randy J. Seeley
R1,896 R1,309 Discovery Miles 13 090 Save R587 (31%) Ships in 12 - 17 working days

When an excessive proportion of the human energy requirement is derived from fat, the likelihood of obesity increases. Any such individual is at risk for diabetes and cardiovascular disease- grave and costly health hazards. The selective control of fat ingestion is a promising solution to these concerns. Existing data suggests that macronutrient intake can be manipulated. Further research is working to create pharmacological tools that will suppress fat consumption. It will also be possible to fight obesity, heart disease and diabetes. Neural and Metabolic Control of Macronutrient Intake systematically discusses the known physiological mechanisms involved in macronutrientselection, including their molecular, genetic and neurochemical aspects. The book is also a critical review of the hypothesis that ingestion of the three nutrients is regulated by separate neural control mechanisms, leaving open the possibility that strategies could be devised to intervene in bodily control systems and alter the proportion of fat in the diet. This reference provides three types of information: First, the basic background of the biochemical and physiological systems as they relate to macronutrient selection. Second, opinions and data concerning to what degree animals and humans show evidence of macronutrient selection. And, third, evidence about how the central nervous system might be involved in the choices animals make among macronutrients.

Analysis of Mixed Data - Methods & Applications (Paperback): Alexander R. de Leon, Keumhee Carriere Chough Analysis of Mixed Data - Methods & Applications (Paperback)
Alexander R. de Leon, Keumhee Carriere Chough
R1,858 Discovery Miles 18 580 Ships in 12 - 17 working days

A comprehensive source on mixed data analysis, Analysis of Mixed Data: Methods & Applications summarizes the fundamental developments in the field. Case studies are used extensively throughout the book to illustrate interesting applications from economics, medicine and health, marketing, and genetics. Carefully edited for smooth readability and seamless transitions between chapters All chapters follow a common structure, with an introduction and a concluding summary, and include illustrative examples from real-life case studies in developmental toxicology, economics, medicine and health, marketing, and genetics An introductory chapter provides a "wide angle" introductory overview and comprehensive survey of mixed data analysis Blending theory and methodology, this book illustrates concepts via data from different disciplines. Analysis of Mixed Data: Methods & Applications traces important developments, collates basic results, presents terminology and methodologies, and gives an overview of statistical research applications. It is a valuable resource to methodologically interested as well as subject matter-motivated researchers in many disciplines.

Nutrition and Exercise Concerns of Middle Age (Paperback): Judy A. Driskell Nutrition and Exercise Concerns of Middle Age (Paperback)
Judy A. Driskell
R1,893 Discovery Miles 18 930 Ships in 12 - 17 working days

Many health professionals today seem to approach sports nutrition and physical activity recommendations with a "one size fits all" approach. Surprisingly, little consideration goes into addressing the changing needs of athletes as they progress in age. Nutrition and Exercise Concerns of Middle Age addresses the specific nutritional and physical activity needs of active individuals thirty to sixty years old. Judy A. Driskell, one of the world's leading experts in the field of sports nutrition, brings together cutting-edge research on the nutritional needs and exercise recommendations for this quickly growing age group. Internationally acclaimed experts on nutrition and kinesiology unveil their research in sports nutrition, endurance and strength training, age-related disorders, and nutrition and exercise recommendations of health organizations. They also explore the role of diet and physical activity in reducing the risk of and in treating age-related diseases such as cancer and cardiovascular disease. Nutrition and Exercise Concerns of Middle Age is a valuable resource for nutritionists, physicians, dieticians, and researchers looking to access authoritative information on exercise and sports nutrition recommendations for middle-age adults.

Introduction to Machine Learning and Bioinformatics (Paperback): Sushmita Mitra, Sujay Datta, Theodore Perkins, George... Introduction to Machine Learning and Bioinformatics (Paperback)
Sushmita Mitra, Sujay Datta, Theodore Perkins, George Michailidis
R1,875 Discovery Miles 18 750 Ships in 12 - 17 working days

Lucidly Integrates Current Activities Focusing on both fundamentals and recent advances, Introduction to Machine Learning and Bioinformatics presents an informative and accessible account of the ways in which these two increasingly intertwined areas relate to each other. Examines Connections between Machine Learning & Bioinformatics The book begins with a brief historical overview of the technological developments in biology. It then describes the main problems in bioinformatics and the fundamental concepts and algorithms of machine learning. After forming this foundation, the authors explore how machine learning techniques apply to bioinformatics problems, such as electron density map interpretation, biclustering, DNA sequence analysis, and tumor classification. They also include exercises at the end of some chapters and offer supplementary materials on their website. Explores How Machine Learning Techniques Can Help Solve Bioinformatics Problems Shedding light on aspects of both machine learning and bioinformatics, this text shows how the innovative tools and techniques of machine learning help extract knowledge from the deluge of information produced by today's biological experiments.

Antimicrobial Pharmacodynamics in Theory and Clinical Practice (Paperback, 2nd edition): Charles H. Nightingale, Paul G.... Antimicrobial Pharmacodynamics in Theory and Clinical Practice (Paperback, 2nd edition)
Charles H. Nightingale, Paul G. Ambrose, George L. Drusano, Takeo Murakawa
R1,897 Discovery Miles 18 970 Ships in 12 - 17 working days

Taking readers from the research laboratory to the bedside, this Second Edition compiles essential information on the pharmacodynamics of all major classes of the antimicrobial armamentarium including penicillins, cephalosposorins, cephamycins, carbapenems, monobactams, aminoglycosides, quinolones, macrolides, antifungals, antivirals, and emerging agents currently in development. Written by experienced professionals in the field, this guide uses an abundance of examples to depict methods to apply pharmacodynamic concepts to everyday clinical practice.

Handbook of Dairy Foods and Nutrition (Paperback, 3rd edition): Gregory D. Miller, Judith K. Jarvis, Lois D. McBean Handbook of Dairy Foods and Nutrition (Paperback, 3rd edition)
Gregory D. Miller, Judith K. Jarvis, Lois D. McBean
R1,881 Discovery Miles 18 810 Ships in 12 - 17 working days

Once again the National Dairy Council has produced the industry reference on the important role of dairy foods in health. Packed with the latest information from the Council's notable scientists, the Handbook of Dairy Foods and Nutrition, Third Edition makes the case for the beneficial role of dairy foods in a variety of conditions and disease states. The handbook begins with a comprehensive overview of the nutritional content and benefits of milk and milk products including cheese and yogurt. The authors explain the effects of dairy intake on cardiovascular health and hypertension. The Dairy Council continues its research review by providing the most up-to-date information on the relationship between dairy intake and colon, breast, and prostate cancers. An entirely new chapter is devoted to addressing recent research about the role of dairy foods in weight management. Supporting the age-old advice that milk gives you strong bones and teeth, this handbook has chapters examining the evidentiary relationship between dairy intake and bone and dental health. A full chapter addresses the condition of lactose digestion, distinguishing lactose intolerance from lactose maldigestion, as well as providing research-based strategies to improve milk tolerance. A summary of dairy's contribution to health throughout the life cycle from childhood and adolescence into adulthood and old age, rounds out this latest installment of the Dairy Council's authoritative reference on the importance of dairy foods in the American diet. Continuing to provide state-of-the-art information on dairy products and nutrition, the Handbook of Dairy Foods and Nutrition, Third Edition is a useful resource for nutrition scientists, dietitians and other health professionals, educators, dairy researchers, and the food industry.

NMR Spectroscopy of Biological Solids (Paperback): A Ramamoorthy NMR Spectroscopy of Biological Solids (Paperback)
A Ramamoorthy
R1,873 Discovery Miles 18 730 Ships in 12 - 17 working days

Over the past decade, a myriad of techniques have shown that solid-state nuclear magnetic resonance (NMR) can be used in a broad spectrum of applications with exceptionally impressive results. Solid-state NMR results can yield high-resolution details on the structure and function of many important biological solids, including viruses, fibril-forming molecules, and molecules embedded in the cell membrane. Filling a void in the current literature, NMR Spectroscopy of Biological Solids examines all the recent developments, implementation, and interpretation of solid-state NMR experiments and the advantages of applying them to biological systems. The book emphasizes how these techniques can be used to realize the structure of non-crystalline systems of any size. It explains how these isotropic and anisotropic couplings interactions are used to determine atomic-level structures of biological molecules in a non-soluble state and extrapolate the three-dimensional structure of membrane proteins using magic-angle spinning (MAS). The book also focuses on the use of multidimensional solid-state NMR methods in the study of aligned systems to provide basic information about the mechanisms of action of a variety of biologically active molecules. Addressing principles, methods, and applications, this book provides a critical selection of solid-state NMR methods for solving a wide range of practical problems that arise in both academic and industrial research of biomolecules in the solid state. NMR Spectroscopy of Biological Solids is a forward-thinking resource for students and researchers in analytical chemistry, bioengineering, material sciences, and structural genomics.

Dictionary of Parasitology (Paperback): Peter J. Gosling Dictionary of Parasitology (Paperback)
Peter J. Gosling
R1,878 Discovery Miles 18 780 Ships in 12 - 17 working days

Although many books have been published on various aspects of human, animal, and plant parasitology, as well as the public health problems associated with parasites, none to date has offered a comprehensive glossary for those confronted with the discipline's exceptionally extensive terminology. To meet this need requires a dedicated text that can house the myriad entries that define all the basic principles and advanced nomenclature of parasitology. The Dictionary of Parasitology reflects current practice in all aspects of parasitology and includes spellings, punctuation, abbreviations, acronyms, symbols, nomenclature, prefixes, and suffixes. It covers the field of modern parasitology with concise, clear, and authoritative precision. The dictionary assigns entries of parasites to the primary divisions of parasitology: human, veterinary, plant, insect, or fish; although in many instances the area of interest may be wide-ranging. The dictionary provides the depth and breadth of knowledge that makes it both an informative and useful volume for beginners and experts in the field, as well as for writers and editors of scientific texts. Entries cover control measures, immunology, physiology, pharmacology, etc., and each are labeled according to the most appropriate area to which they relate. Attach tear sheet from text Providing more than 11,500 entries, the Dictionary of Parasitology, sets a standard that will allow those in the field to communicate with essential scientific accuracy.

Write It Down - Guidance for Preparing Effective and Compliant Documentation (Paperback, 2nd edition): Janet Gough Write It Down - Guidance for Preparing Effective and Compliant Documentation (Paperback, 2nd edition)
Janet Gough
R1,892 Discovery Miles 18 920 Ships in 12 - 17 working days

A well-understood tenet exists among the FDA and other regulatory bodies: if you didn't write it down, it didn't happen. And if it didn't happen, your company stands to lose time, money, and perhaps its competitive edge. Write it Down: Guidance for Preparing Effective and Compliant Documentation provides you with the tools you need to put effective documentation in place. The book has a three-pronged focus: to help writers understand the why of what they must write and the current industry standards for good documentation practices, to provide effective examples of a broad spectrum of documents, and to supply an in-depth explanation of grammar and punctuation conventions. Substantially expanded, the second edition focuses on the regulations, the need to document, and the range of documentation that must be in place to support therapeutic products from discovery through market. Readers will find useful examples of good writing, many provided by people in the industry. Letters and memos; short reports of varied topics, including equipment evaluation, vendor audit, and trip review; standard operating procedures, laboratory methods, and training materials; documentation for an IQ/OQ/PQ project; a journal article; and excerpts from a development report and a dossier are among the many examples. The book also gives a thorough explanation of grammar, punctuation, and usage, with a strong emphasis on the components of the language that pose difficulties for non-native writers of English. This book is a must for people working in or preparing to work in environments that produce drugs, medical devices, or biologics for sale in countries that have stringent regulatory requirements and where the business language is English. Firmly placing the writing task in context of the existing laws and guidances, the book offers valuable insights into managing systems and producing documentation that meets the requirements of the binding regulations.

Childhood Obesity Prevention and Treatment (Paperback, 2nd edition): Jana Parizkova, Andrew Hills Childhood Obesity Prevention and Treatment (Paperback, 2nd edition)
Jana Parizkova, Andrew Hills
R1,898 Discovery Miles 18 980 Ships in 12 - 17 working days

Childhood Obesity Prevention and Treatment, Second Edition summarizes the latest scientific knowledge on obesity in children. This edition focuses on the developmental aspects of obesity, especially on the influences and factors predisposing individuals to obesity from early periods of life. This new body of knowledge stems from both basic research and recent epidemiological and clinical studies. All chapters are updated and special attention is given to the prevention of obesity in the context of developmental physiology, lifestyle modification, and dietary and physical activity approaches. Highlighting the most recent research, this timely book covers a broad range of aspects related to the prevention and management of childhood obesity. It emphasizes early intervention and an integrated behavioral approach to overcome the ongoing challenge of this global epidemic. Features * Updates all chapters and includes new research on growing populations of obesity in the Third World * Provides information on promoting health as a means to reduce obesity * Focuses on the developmental aspects of obesity

21 CFR Part 11 - Complete Guide to International Computer Validation Compliance for the Pharmaceutical Industry (Paperback):... 21 CFR Part 11 - Complete Guide to International Computer Validation Compliance for the Pharmaceutical Industry (Paperback)
Orlando Lopez
R1,857 Discovery Miles 18 570 Ships in 12 - 17 working days

Covering regulatory requirements stipulated by the FDA, this book delineates the organization, planning, verification, and documentation activities and procedural controls required for compliance with worldwide computer systems validation regulations. The author introduces supporting technologies such as encryption and digital signatures and places regulatory compliance within the context of quality assurance. He demonstrates the importance of integrating validation activities into the system lifecycle using a structured top-down approach. He covers practical applications of quality assurance and engineering techniques as they relate to the development of systems fit to meet user and regulatory requirements.

Nutrition and Exercise Immunology (Paperback): David C. Nieman, Bente Klarlund Pedersen Nutrition and Exercise Immunology (Paperback)
David C. Nieman, Bente Klarlund Pedersen
R1,849 Discovery Miles 18 490 Ships in 12 - 17 working days

Like an army of millions ready to defend its territory, the human immune system acts as the body's primary line of defense-a complex network of interacting cells that protects us from pathogens and other foreign substances. But many components of the immune system exhibit change after prolonged, heavy exertion, indicating that it is suppressed and stressed, albeit transiently, following prolonged endurance exercise. For marathon runners, distance swimmers and any other endurance athlete who undergoes repeated cycles of heavy exertion, a weakened immune system could lead to health complications such as respiratory infection. As a result, interest in various nutrient supplements with the potential to counter exercise-induced immunosuppression has grown. Nutrition and Exercise Immunology reviews the link between nutrition and immune function, with special application to athletic endeavor. Written by respected researchers in sports medicine and exercise immunology, this text covers topics such as carbohydrates and the immune response to prolonged exertion; protein, exercise, and immunity; and vitamins, immunity, and infection risk in athletes. It also takes a look at future directions in nutrition and exercise immunology. For sports medicine professionals, dietitians, nutritionists, exercise immunologists, as well as endurance athletes, Nutrition and Exercise Immunology provides an important and in-depth look into this exciting, new area of scientific research.

Excipient Toxicity and Safety (Paperback): Myra L. Weiner, Lois A. Kotkoskie Excipient Toxicity and Safety (Paperback)
Myra L. Weiner, Lois A. Kotkoskie
R1,876 Discovery Miles 18 760 Ships in 12 - 17 working days

This book reviews the history, regulatory status, pharmacopeial specifications, and harmonization of pharmaceutical excipients in the United States and Europe, and provides a comprehensive understanding of the current scientific basis for safety evaluation and risk assessment. Examines excipients as a unique class of products and explores new procedures for determining toxicity! A timely and unique addition to the pharmaceutical literature, containing over 570 citations that support and enhance the text, Excipient Toxicity and Safety identifies the differences between excipients (inactive ingredients), food ingredients, and drug products evaluates issues of dose administration, species selection, and study design for various routes of exposure provides detailed information on the historical uses of excipients in drug formulations clarifies the Safety Committee of the International Pharmaceutical Excipients Council's (IPEC) guidelines and technical specifications for conducting tests for each route of exposure explains how data generated in toxicity models are applied to identify hazards in drug formulations details exposure assessment to link hazard identification with risk considers the requirements and importance of purity specifications and much more! Excipient Toxicity and Safety is a blue-ribbon reference ideal for pharmacists; toxicologists; pharmacologists; analytical chemists; quality control, quality assurance, and regulatory compliance managers; and upper-level undergraduate and graduate students in these disciplines.

Bayesian Biostatistics (Paperback): Donald A. Berry, Dalene Stangl Bayesian Biostatistics (Paperback)
Donald A. Berry, Dalene Stangl
R1,921 Discovery Miles 19 210 Ships in 12 - 17 working days

This work provides descriptions, explanations and examples of the Bayesian approach to statistics, demonstrating the utility of Bayesian methods for analyzing real-world problems in the health sciences. The work considers the individual components of Bayesian analysis.;College or university bookstores may order five or more copies at a special student price, available on request from Marcel Dekker, Inc.

Electromagnetic Compatibility in Medical Equipment - A Guide for Designers and Installers (Paperback): William D. Kimmel, Daryl... Electromagnetic Compatibility in Medical Equipment - A Guide for Designers and Installers (Paperback)
William D. Kimmel, Daryl Gerke
R1,863 Discovery Miles 18 630 Ships in 12 - 17 working days

Co-published with the IEEE Press, this book is a practical, hands-on guide to EMC issues for medical device designers and installers. It addresses electromagnetic interference and covers the basics of EMC design, physics, and installation, minimizing theory and concentrating upon the correct way to ground and shield. Covering EMC from the inside out, the book provides the basics of electronics, discusses and evaluates problems and common causes, and explores effective remedial techniques at three levels: circuit, box, and interconnect. It contains appendices that provide important reference material such as constants and conversion factors.

EDHF - The Complete Story (Paperback): Michel Feletou, Paul Vanhoutte EDHF - The Complete Story (Paperback)
Michel Feletou, Paul Vanhoutte
R673 Discovery Miles 6 730 Ships in 10 - 15 working days

The advances made in vascular biology in the last 25 years have considerably changed the perception that one could have of the endothelial cells. Once considered as a diffusion barrier preventing the access of the blood cells to the vascular matrix, the endothelium is now recognized as playing a major role in the control of blood fluidity, platelet aggregation, and vascular tone, but also in immunology, inflammation, angiogenesis, and for serving as a metabolizing and an endocrine organ. -- from the preface Cardiovascular diseases, so prevalent in the Western world during the twentieth century, could well become the scourge of the twenty-first century in emerging countries as well as the West. Endothelial dysfunction linked to an imbalance in the synthesis and/or release of contracting and relaxing factors is often evoked to explain the initiation of the cardiovascular pathology or its development and perpetuation. Two decades ago, when nitric oxide was demonstrated to mediate endothelium-dependent relaxations, the vascular world seemed convinced that nitric oxide was the ultimate and sole explanation for such relaxations. However not everyone agreed. EDHF: The Complete Story is the work of two leading researchers who did not accept that simple conclusion, but instead continued to search, along with others, for a deeper understanding of the ways in which endothelial cells communicate with the underlying smooth muscle to signal it to hyperpolarize. Now with most, if not all, of those ways, uncovered, the authors offer this summary as way of bringing closure to the quest. This monograph reports on the work of many researchers. It summarizes the significant recent discoveries concerning endothelium-dependent hyperpolarizations, which are likely to play a much more important role in cardiovascular physiology and pathology than was originally foreseen Extensively illustrated with original diagrams and schematics that su

Modelling Evolution - A New Dynamic Account (Paperback): Eugene Earnshaw-Whyte Modelling Evolution - A New Dynamic Account (Paperback)
Eugene Earnshaw-Whyte
R1,255 Discovery Miles 12 550 Ships in 12 - 17 working days

Evolution by natural selection explains the tree of life and the complex adaptations found throughout nature. The power and versatility of evolutionary explanations have proved tempting to scientists outside of biology, but adapting evolutionary concepts to new domains has been challenging. Even within biology, there are many difficult questions and problem cases that face evolutionary theory. Modelling Evolution offers a new, general account of evolution by natural selection that identifies the essential features of evolutionary models that transcend any particular discipline. Evolution by natural selection in its broad sense is the systemic advantage of a type, in contrast to the narrow definition using heritable variation in fitness. This account is explained, contextualised and applied to a variety of questions in both biology and the social sciences. Offering an accessible and comprehensive account of evolution that is applicable both to biology and the broader social sciences, Modelling Evolution will appeal to students and researchers interested in fields such as biology, economics, sociology, history, and psychology.

Multiple Comparisons, Selection and Applications in Biometry (Paperback): Fred M. Hoppe Multiple Comparisons, Selection and Applications in Biometry (Paperback)
Fred M. Hoppe
R1,405 Discovery Miles 14 050 Ships in 12 - 17 working days

Aims to provide in-depth descriptions of the latest developments in multiple comparison methods and selection procedures, while emphasizing biometry. This text is published in honour of the 70th birthday of Charles W. Dunnett - a pioneer in statistical methodology.

Theory of Factorial Design - Single- and Multi-Stratum Experiments (Paperback): Ching-Shui Cheng Theory of Factorial Design - Single- and Multi-Stratum Experiments (Paperback)
Ching-Shui Cheng
R1,879 Discovery Miles 18 790 Ships in 12 - 17 working days

Bringing together both new and old results, Theory of Factorial Design: Single- and Multi-Stratum Experiments provides a rigorous, systematic, and up-to-date treatment of the theoretical aspects of factorial design. To prepare readers for a general theory, the author first presents a unified treatment of several simple designs, including completely randomized designs, block designs, and row-column designs. As such, the book is accessible to readers with minimal exposure to experimental design. With exercises and numerous examples, it is suitable as a reference for researchers and as a textbook for advanced graduate students. In addition to traditional topics and a thorough discussion of the popular minimum aberration criterion, the book covers many topics and new results not found in existing books. These include results on the structures of two-level resolution IV designs, methods for constructing such designs beyond the familiar foldover method, the extension of minimum aberration to nonregular designs, the equivalence of generalized minimum aberration and minimum moment aberration, a Bayesian approach, and some results on nonregular designs. The book also presents a theory that provides a unifying framework for the design and analysis of factorial experiments with multiple strata (error terms) arising from complicated structures of the experimental units. This theory can be systematically applied to various structures of experimental units instead of treating each on a case-by-case basis.

Mixed Effects Models for Complex Data (Paperback): Lang Wu Mixed Effects Models for Complex Data (Paperback)
Lang Wu
R1,883 Discovery Miles 18 830 Ships in 12 - 17 working days

Although standard mixed effects models are useful in a range of studies, other approaches must often be used in correlation with them when studying complex or incomplete data. Mixed Effects Models for Complex Data discusses commonly used mixed effects models and presents appropriate approaches to address dropouts, missing data, measurement errors, censoring, and outliers. For each class of mixed effects model, the author reviews the corresponding class of regression model for cross-sectional data. An overview of general models and methods, along with motivating examples After presenting real data examples and outlining general approaches to the analysis of longitudinal/clustered data and incomplete data, the book introduces linear mixed effects (LME) models, generalized linear mixed models (GLMMs), nonlinear mixed effects (NLME) models, and semiparametric and nonparametric mixed effects models. It also includes general approaches for the analysis of complex data with missing values, measurement errors, censoring, and outliers. Self-contained coverage of specific topicsSubsequent chapters delve more deeply into missing data problems, covariate measurement errors, and censored responses in mixed effects models. Focusing on incomplete data, the book also covers survival and frailty models, joint models of survival and longitudinal data, robust methods for mixed effects models, marginal generalized estimating equation (GEE) models for longitudinal or clustered data, and Bayesian methods for mixed effects models. Background materialIn the appendix, the author provides background information, such as likelihood theory, the Gibbs sampler, rejection and importance sampling methods, numerical integration methods, optimization methods, bootstrap, and matrix algebra. Failure to properly address missing data, measurement errors, and other issues in statistical analyses can lead

Pharmaceutical Experimental Design and Interpretation (Paperback, 2nd edition): N. Anthony Armstrong Pharmaceutical Experimental Design and Interpretation (Paperback, 2nd edition)
N. Anthony Armstrong
R1,856 Discovery Miles 18 560 Ships in 12 - 17 working days

Completely revised and updated, Pharmaceutical Experimental Design and Interpretation, Second Edition explains the major methods of experimental design and evaluation such as multivariate, sequential, and principal components analysis. With new sections on neural networks, artificial intelligence, fractional designs, and optimization techniques, this source will prove invaluable to anyone involved in the design and execution of pharmaceutical research studies and the interpretation of study data.

Dictionary of Nutraceuticals and Functional Foods (Paperback): Michael Eskin, Snait Tamir Dictionary of Nutraceuticals and Functional Foods (Paperback)
Michael Eskin, Snait Tamir
R1,894 Discovery Miles 18 940 Ships in 12 - 17 working days

Health professionals are recognizing the major role that nutraceuticals play in health enhancement. As a result, there is a dramatic increase in research aimed at identifying new functional foods and nutraceuticals. There is not, however, a single source that presents this research in a thorough and accessible manner. Comprehensive and complete, the Dictionary of Nutraceuticals and Functional Foods is the first reference of its kind written explicitly for this rapidly developing field. The book provides clearly written, concise, science-based information on over 470 nutraceutical and functional food products and compounds. Each entry lists the most current information on the product or compound and its role in the promotion of health or the prevention of disease, as well as peer-reviewed literature references. In addition, this thorough reference contains 172 chemical structures, 102 figures, 73 schemes, and 64 tables to facilitate recognition and understanding. Concise and accessible, the Dictionary of Nutraceuticals and Functional Foods is a convenientsingle source reference that defines the most commonly used terms in the field of nutraceuticals and functional foods.

Nonparametric Statistical Methods For Complete and Censored Data (Paperback): M.M. Desu, D. Raghavarao Nonparametric Statistical Methods For Complete and Censored Data (Paperback)
M.M. Desu, D. Raghavarao
R1,875 Discovery Miles 18 750 Ships in 12 - 17 working days

Balancing the "cookbook" approach of some texts with the more mathematical approach of others, Nonparametric Statistical Methods for Complete and Censored Data introduces commonly used non-parametric methods for complete data and extends those methods to right censored data analysis. Whenever possible, the authors derive their methodology from the general theory of statistical inference and introduce the concepts intuitively for students with minimal backgrounds. Derivations and mathematical details are relegated to appendices at the end of each chapter, which allows students to easily proceed through each chapter without becoming bogged down in a lot of mathematics. In addition to the nonparametric methods for analyzing complete and censored data, the book covers optimal linear rank statistics, clinical equivalence, analysis of block designs, and precedence tests. To make the material more accessible and practical, the authors use SAS programs to illustrate the various methods included. Exercises in each chapter, SAS code, and a clear, accessible presentation make this an outstanding text for a one-semester senior or graduate-level course in nonparametric statistics for students in a variety of disciplines, from statistics and biostatistics to business, psychology, and the social scientists. Prerequisites: Students will need a solid background in calculus and a two-semester course in mathematical statistics.

Components of Variance (Paperback): D.R. Cox, P.J. Solomon Components of Variance (Paperback)
D.R. Cox, P.J. Solomon
R1,846 Discovery Miles 18 460 Ships in 12 - 17 working days

Identifying the sources and measuring the impact of haphazard variations are important in any number of research applications, from clinical trials and genetics to industrial design and psychometric testing. Only in very simple situations can such variations be represented effectively by independent, identically distributed random variables or by random sampling from a hypothetical infinite population. Components of Variance illuminates the complexities of the subject, setting forth its principles with focus on both the development of models for detailed analyses and the statistical techniques themselves. The authors first consider balanced and unbalanced situations, then move to the treatment of non-normal data, beginning with the Poisson and binomial models and followed by extensions to survival data and more general situations. In the final chapter, they discuss ways of extending and assessing various models, including the study of exceedances, the use of nonlinear representations, the study of transformations of the response variable, and the detailed examination of the distributional form of the underlying random variables. Careful signposting and numerous examples from genetic data analysis, clinical trial design, longitudinal data analysis, industrial design, and meta-analysis make this book accessible - and valuable - not only to statisticians but to all applied research scientists who use statistical methods.

Causal Analysis in Biomedicine and Epidemiology - Based on Minimal Sufficient Causation (Paperback): Mikel Aickin Causal Analysis in Biomedicine and Epidemiology - Based on Minimal Sufficient Causation (Paperback)
Mikel Aickin
R1,854 Discovery Miles 18 540 Ships in 12 - 17 working days

"Provides current models, tools, and examples for the formulation and evaluation of scientific hypotheses in causal terms. Introduces a new method of model parametritization. Illustrates structural equations and graphical elements for complex causal systems."

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