This new volume provides exhaustive knowledge on a wide range of natural products and holistic concepts that have provided promising in the treatment of leishmaniasis. Including the major natural therapies as well as traditional formulations, over 300 medicinal plants and 150 isolated compounds that are reported to have beneficial results in the treatment of the disease are explored in this comprehensive work. This book also acts as an important resource on various anti-inflammatory plants used to treat various inflammatory conditions of the disease.

Outlines the basics of nutrition for healthcare professionals. Directed towards an international audience; written from the holistic perspective. There has been a definite shift in our perception and understanding of foods and diet. More attention is being given towards how we grow and cultivate food sources whilst being mindful about the environmental impact this may have - this book is timely, the medical community is now giving due importance to dietary content.

Psychopathy: The Basics is an accessible text that provides a compact introduction to the major findings and debates concerning this complex personality disorder. The book provides an overview of the field and covers a wide range of research findings from genetics to psychosocial developmental explanations. It begins with an exploration of the historical conception of the phenomenon of psychopathy and goes on to discuss its social and cultural accounts. It also delves into biologically based explanations including genetic and evolutionary approaches along with criminological and entrepreneurial types of psychopathy. Offering a balanced perspective, the book addresses the nature-nurture debate in the field and also discusses widely accepted personality traits of psychopaths. Lastly, it also provides a glossary of key terms and suggestions for further reading This text will be an essential read for students of forensic psychology, or criminology. It is also an ideal starting point for those interested in the science of psychopathy and personality disorders.

Nearly ten years after the first edition of Water-Related Death Investigation: Practical Methods and Forensic Applications, water death cases continue to be improperly investigated. The pathologist's report can determine the cause of death as a drowning, but the manner of death is the most challenging to prove. The report will not determine if a victim jumped into the water to commit suicide, fell into the water accidentally, or was pushed in as a homicidal act. Many drowning cases do not reflect injury to the body, so evidence collected at the scene plays a vital role. The importance of an on-scene body assessment cannot be overemphasized. Often, the body evidence begins to change rapidly upon recovery and may not be present during an autopsy. Written statements on the scene are an effective tool to use to determine the accuracy of information given to arriving officers. These statements need to be written by the witnesses themselves as well as the reporting person. The "Show Me" technique can also help reveal discrepancies in a person's version of what occurred as well as aid in providing the most details to an incident as is humanly possible. This second edition includes updated information on the latest technology to assist water death investigators. Parabon Snapshot can help determine the faceless identity of skeletal remains and help locate potential suspects using the science of DNA. Drones can aid in locating missing persons as well as human remains, even months after death. Updated information is provided regarding fingerprints from submerged objects, and Carbon-14 can help determine the origin of a found corpse. Key Features: Thoroughly reviews the physiological aspects of drowning Reveals the investigative characteristics inherent to various scenes of water-related deaths Highlights certain "red flag" indicators that may point to foul play or scene staging Outlines autopsy protocols, trial preparation, and expert witness testimony Provides numerous case studies and numerous illustrations to further clarify key points presented in the text Coauthored by a Master Water Death Investigator and an experienced forensic pathologist, Water-Related Death Investigation: Practical Methods and Forensic Applications, Second Edition merges the essentials of evidence collection and field investigation with autopsy best practices and laboratory testing. It will continue to serve as a valuable resource for the various professionals involved in these cases.

Death Investigation: A Field Guide, Second Edition is updated and expanded to include a chronological analysis of the death scene investigative process from the first notification to the autopsy and final report. This book is written for the standpoints of a forensic pathologist and a forensic toxicologist emphasizing essential elements of the death investigation and how the results impact the final cause and manner of death. Topics discussed include how to assess the body at the scene and how to properly investigate natural and unnatural deaths. The book discusses various means and causes of deaths, demonstrating how death manifests in various parts of the body. A section on traumatic injuries examines and illustrates with color photographs blunt force, sharp force, gunshot wounds, and a host of other injuries that the investigator is likely to confront. Natural death conditions and disease are discussed in a separate chapter devoted to the most common manner of death. The Second Edition is fully updated with new added sections which cover forensic toxicology, statutory responsibilities, documentation and photography of the scene, DNA identification and possible contamination issues, decomposition, managing and utilizing electronic medical records, anaphylaxis and allergic reactions, infectious diseases such as Covid-19, acute peritonitis, and more. Despite including over 200 full-color photos, the book retains a succinct, handy format that is invaluable to those facing, and tasked with investigating, the reality of death on a day-to-day basis. Death Investigation: A Field Guide, Second Edition continues to serve as an invaluable resource for Crime Scene Investigators (CSIs), coroners, Medical Death Investigators (MDI), and medical examiner professionals.

The Multiplayer Classroom: Game Plans is a companion to The Multiplayer Classroom: Designing Coursework as a Game, now in its second edition from CRC Press. This book covers four multiplayer classroom projects played in the real world in real time to teach and entertain. They were funded by grants or institutions, collaborations between Lee Sheldon, as writer/designer, and subject matter experts in various fields. They are written to be accessible to anyone--designer, educator, or layperson--interested in game-based learning. The subjects are increasingly relevant in this day and age: physical fitness, Mandarin, cybersecurity, and especially an online class exploring culture and identity on the internet that is unlike any online class you have ever seen. Read the annotated, often-suspenseful stories of how each game, with its unique challenges, thrills, and spills, was built. Lee Sheldon began his writing career in television as a writer-producer, eventually writing more than 200 shows ranging from Charlie's Angels (writer) to Edge of Night (head writer) to Star Trek: The Next Generation (writer-producer). Having written and designed more than forty commercial and applied video games, Lee spearheaded the first full writing for games concentration in North America at Rensselaer Polytechnic Institute and the second writing concentration at Worcester Polytechnic Institute. He is a regular lecturer and consultant on game design and writing in the United States and abroad. His most recent commercial game, the award-winning The Lion's Song, is currently on Steam. For the past two years he consulted on an "escape room in a box," funded by NASA, that gives visitors to hundreds of science museums and planetariums the opportunity to play colonizers on the moon. He is currently writing his second mystery novel.

The perfect companion for A-Level AQA Biology, this new and improved CGP Complete Revision & Practice Guide is ideal for reference throughout both years and preparing for those final exams! It has straightforward study notes, helpful examples and full-colour diagrams. We've included more challenging exam practice than ever before with plenty of practice questions and exam-style questions (with detailed answers) for every topic - plus a section of mixed (synoptic) practice testing different parts of the course. To round things off there are sections of in-depth advice on Practical Skills and how to pick up top marks in the exams. There's even a free Online Edition of the whole book - just use the code printed inside the book to access it on your PC, Mac or tablet. For even more practice don't miss CGP's A-Level Biology Exam Practice Workbook (9781782949107).

Exam Board: SQA Level: Higher Subject: Human Biology Two books in one! Combining a revision guide and a full set of practice test papers, this fantastic resource is all you need to revise for the exam. The revision guide * Covers all of the topics in the Higher Human Biology curriculum, broken down into manageable chunks for easy revision * Clearly explains key concepts, research evidence and real-life applications * Contains Quick Tests to let students check their knowledge and understanding as they go along The practice test papers * Are in the format and the style of the SQA exam, giving students an opportunity to practice taking the Higher Human Biology exam Marking instructions and sample answers are provided online, so students can check their progress.

Crime scene reconstruction (CSR) is today's hot topic. The immense proliferation of television, print, and electronic media directed at this area has generated significant public interest, albeit occasionally encouraging inaccurate perceptions. Practical Crime Scene Analysis and Reconstruction bridges the gap between perception and reality, helping readers understand the nature of the scientific method and teaching the proper application of its components. A proven methodology The book begins by recounting the history of crime scene analysis and exploring fundamental principles. Then the authors introduce their proven methodology, known as Event Analysis. This technique defines specific actions, discusses the order of those actions, and offers significant insight into determining what did or did not happen in the course of the incident under investigation. Using case studies and more than 200 color photos, the book demonstrates this method and how it can be used to explain clues that would otherwise be puzzling or ambiguous. Practical advice from the crime scene to the courtroom The authors show how to resolve significant questions that arise in the course of CSR through the use of an event analysis worksheet. The book also discusses crime scene protocol, bloodstain pattern analysis, gunshot investigation, and forensic pathology and the human body. The final chapters provide instruction on writing crime scene reports, discuss ethical issues, and give advice on courtroom presentation. Includes color photos demonstrating the science of CSR on: Superposition Timing and sequence Bloodstain analysis Ballistics Wound patterns

This reference, now in its second edition, is a comprehensive guide that focuses on the practical aspects of excavating and recovering human remains, as well as any associated evidence, from crime scenes. It highlights the protocols and techniques that are used to successfully survey, map, recover, document, collect, and transport evidence. New additions to the reference include discussion questions and suggested readings, updated mapping and measuring techniques, including a section on GIS and backpack differential GPS systems, expanded information on botany, DNA, and soil, and non-forensic burial contexts. Almost 200 illustrations are included to help clarify concepts.

Practical Analysis and Reconstruction of Shooting Incidents, Second Edition presents a holistic approach to shooting incident analysis and reconstruction, covering the entire spectrum of related sub-disciplines of forensic science. The book reviews basic firearm design and function, ammunition components, and terminology, explaining what constitutes pertinent evidence and appropriate results relative to autopsies, forensic laboratory analysis, and reenactments. The second edition features numerous additions including: Four new chapters Complete and extensive updates to all 16 original chapters Three case studies contributed by renowned professionals in the field New and revised exercises at the ends of chapters, with answers provided An expanded glossary of terminology Nearly 340 figures and illustrations, with several in full color New and updated references and suggested readings Appendices containing relevant terminology, checklists, and other resources The book details the mathematics of shooting reconstruction in clear, precise language that allows readers-both those with and without extensive science backgrounds-to apply a logical thought process to the evaluation of shooting scene evidence in order to establish the probable related events to the shooting incident. This new edition provides up-to-date information for field investigators to recognize, preserve, document, and interpret the physical evidence typically found after shooting incidents. In addition to the hundreds of illustrations, the book uses both case studies and step-by-step outlines to clearly describe the required analytical processes involved in reconstructing and interpreting shooting incident scenes.

In the recent years, considerable research has been carried out evaluating natural substances as antioxidative additives in food products, leading to novel combinations of antioxidants and the development of novel food products. In addition to their antioxidative capacity, these natural additives have positive effects on the human body with documented health benefits. This valuable new book provides an overview of natural antioxidants, their sources, methods of extraction, regulatory aspects, and application techniques, specifically focusing on different foods of animal origin to improve their oxidative stability.

The Psychology of Death Investigations outlines definitively how behavioral evidence can often provide the necessary components and "missing pieces" to complement physical evidence as an essential tool for incident reconstruction. In order to determine the direction of an investigation and to prioritize leads, if necessary, death investigators must establish the manner of a death: natural, accident, homicide or suicide. The most overlooked aspect of death investigation is the psychological dimension, which can provide unique leads, correct false assumptions, enhance investigative awareness, and solve cases in surprising ways. In an estimated 10-20% of cases, the manner of death cannot be determined, or worse, has been erroneously categorized. Since many jurisdictions can't afford behavioral consultants, this book has been written to provide practical information for a basic psychological analysis. If the circumstances surrounding a death are equivocal, psychological consultants can compile information retrospectively about a deceased person's mental state and possible motive to assist with unravelling ambiguity about the manner of death. This is the primary function of a psychological autopsy, and, as such, this is the first book of its kind dedicated solely to the topic. In the event that the manner of death is determined to be a homicide, behavioral profiling can help to focus the potential pool of suspects. Professionals and students alike will benefit from the exercise of cognitive awareness and the application of psychological logic presented. Psychologists, medical examiners, coroners, attorneys, fraud examiners, law enforcement personnel, death and homicide investigators, and students enrolled in criminal profiling, forensic psychology, and criminal justice programs will find this text to be a compelling and insightful reference to add to their professional toolkit.

Translational bioinformatics (TBI) involves development of storage, analytics, and advanced computational methods to harvest knowledge from voluminous biomedical and genomic data into 4P healthcare (proactive, predictive, preventive, and participatory). Translational Bioinformatics Applications in Healthcare offers a detailed overview on concepts of TBI, biological and clinical databases, clinical informatics, and pertinent real-case applications. It further illustrates recent advancements, tools, techniques, and applications of TBI in healthcare, including Internet of Things (IoT) potential, toxin databases, medical image analysis and telemedicine applications, analytics of COVID-19 CT images, viroinformatics and viral diseases, and COVID-19-related research. Covers recent technologies such as Blockchain, IoT, and Big data analytics in bioinformatics Presents the role of translational bioinformatic methods in the field of viroinformatics, as well as in drug development and repurposing Includes translational healthcare and NGS for clinical applications Illustrates translational medicine systems and their applications in better healthcare Explores medical image analysis with focus on CT images and novel coronavirus disease detection Aimed at researchers and graduate students in computational biology, data mining and knowledge discovery, algorithms and complexity, and interdisciplinary fields of studies, including bioinformatics, health-informatics, biostatistics, biomedical engineering, and viroinformatics. Khalid Raza is an Assistant Professor, the Department of Computer Science, Jamia Millia Islamia (Central University), New Delhi. His research interests include translational bioinformatics, computational intelligence methods and its applications in bioinformatics, viroinformatics, and health informatics. Nilanjan Dey is an Associate Professor, the Department of Computer Science and Engineering, JIS University, Kolkata, India. His research interests include medical imaging, machine learning, computer-aided diagnosis, and data mining.

The bioscience of immunology has given us a better understanding of human health and disease. Artificial intelligence (AI) has elevated that understanding and its applications in immunology to new levels. Together, AI for immunology is an advancing horizon in health care, disease diagnosis, and prevention. From the simple cold to the most advanced autoimmune disorders and now pandemics, AI for immunology is unlocking the causes and cures. Key features: A highly accessible and wide-ranging short introduction to AI for immunology Includes a chapter on COVID-19 and pandemics Includes scientific and clinical considerations, as well as immune and autoimmune diseases

The bioscience of immunology has given us a better understanding of human health and disease. Artificial intelligence (AI) has elevated that understanding and its applications in immunology to new levels. Together, AI for immunology is an advancing horizon in health care, disease diagnosis, and prevention. From the simple cold to the most advanced autoimmune disorders and now pandemics, AI for immunology is unlocking the causes and cures. Key features: A highly accessible and wide-ranging short introduction to AI for immunology Includes a chapter on COVID-19 and pandemics Includes scientific and clinical considerations, as well as immune and autoimmune diseases

Ecological Restoration and Management of Longleaf Pine Forests is a timely synthesis of the current understanding of the natural dynamics and processes in longleaf pine ecosystems. This book beautifully illustrates how incorporation of basic ecosystem knowledge and an understanding of socioeconomic realities shed new light on established paradigms and their application for restoration and management. Unique for its holistic ecological focus, rather than a more traditional silvicultural approach, the book highlights the importance of multi-faceted actions that robustly integrate forest and wildlife conservation at landscape scales, and merge ecological with socioeconomic objectives for effective conservation of the longleaf pine ecosystem.

A myriad of different scenarios await those entering the field of forensic pathology, ranging from gunshot wounds to asphyxiation to explosives to death from addiction. Essential Forensic Pathology: Core Studies and Exercises helps prepare pathologists in training by establishing what they must know about the most common death scenes they will encounter. The book begins by discussing the coaching objectives in medical education and follows with a description of the 15 different rotations of the forensic pathology resident. Using a consistent and concise format, the book describes the facility where the rotation takes place, the necessary skills, the laboratory equipment, and other components of the rotation. The main portion of the book presents forensic pathology essentials in the form of learning objectives-each delineated with a code: "M" for items students must know, and "S" for those they must do. This section begins by discussing the government's role, describes medical examiner and coroner systems, and analyzes the academic discipline of forensic pathology. Next, the book focuses on hands-on elements of forensic pathology, with chapters on scene investigation, identification, and postmortem changes (signs of death). Objectives are also presented for various causes of death, including gunshot wounds, stab wounds, asphyxiation, sex-related death, and death from addiction. Additional chapters cover bombs and explosive devices, mental disease, epidemics, and issues related to forensic entomology. Each chapter contains a list of pertinent vocabulary and references for further study. By mastering the objectives contained in each chapter of this manual, forensic pathology students will be ready to pass certification exams and work confidently in the field.

In recent years, the use of illegally produced firearms has increased exponentially worldwide. These are often cheap, nonstandard firearms that defy known classification and identification criteria. The use of unusual firearms in crimes has frequently led to unpredictable and misleading reconstruction of shooting incidents. In this book, internationally known forensic firearm expert, J.K. Sinha, presents a detailed forensic study of unusual firearms, with the goal of helping crime-scene investigators to minimize erroneous conclusions in cases where these types of firearms are used. Based on his extensive experimentation with more than 1,000 nonstandard firearms, the author identifies new class characteristic parameters needed to establish linkage of projectiles with irregular rifled and smoothbore barrels. The book begins with an introduction to unusual firearms and proceeds to discuss forensic investigation of fired bullets, medico-legal evidence, barrel marks on fired shots, and investigation of fired cartridges and shot charge. Chapters also cover topics such as timing of firing, unusual rifling marks, shooter identification, and unusual bullet hole evaluations. Providing concise yet complete techniques for making forensic analyses and conclusions, this is the first book of its kind to critically examine the use of unusual, nonstandard firearms in perpetrating crimes. It is intended for professionals and academicians working in the field: forensic firearm experts and consultants, forensic medicine professionals and medico-legal experts, prosecution and defense attorneys, enforcement agencies and judiciary, university students and researchers studying forensic science, forensic medicine, criminology and law.

New technologies, including DNA and digital databases that can compare known and questioned exemplars, have transformed forensic science and greatly impacted the investigative process. They have also made the work more complicated. Obtaining proper resources to provide quality and timely forensic services is frequently a challenge for forensic managers, who are often promoted from casework duties and must now learn a whole new set of leadership skills. The interdisciplinary and scientific nature of laboratories requires strong leadership ability to manage complex issues, often in adversarial settings. Forensic Laboratory Management: Applying Business Principles provides laboratory managers with business tools that apply the best science to the best evidence in a manner that increases the efficiency and effectiveness of their management decision making. The authors present a performance model with seven recommendations to implement, illustrating how forensic managers can serve as leaders and strategically improve the operation and management in scientific laboratories. Topics include: Key business metrics and cost-benefit analyses Ethical lapses: why they occur, possible motives, and how problems can be prevented Forensic training, education, and institutes ISO/IEC 17025 accreditation implementation The book includes case studies simulating a working laboratory in which readers can apply business tools with actual data reinforcing discussion concepts. Each chapter also includes a brief review of current literature of the best management theories and practice. The downloadable resources supply two mock trial transcripts and associated case files along with PowerPoint (R) slides from Dr. George Carmody's workshop on Forensic DNA Statistics and Dr. Doug Lucas's presentation on ethics.

Maintaining a practical perspective, Bioequivalence and Statistics in Clinical Pharmacology, Second Edition explores statistics used in day-to-day clinical pharmacology work. The book is a starting point for those involved in such research and covers the methods needed to design, analyze, and interpret bioequivalence trials; explores when, how, and why these studies are performed as part of drug development; and demonstrates the methods using real world examples. Drawing on knowledge gained directly from working in the pharmaceutical industry, the authors set the stage by describing the general role of statistics. Once the foundation of clinical pharmacology drug development, regulatory applications, and the design and analysis of bioequivalence trials are established, including recent regulatory changes in design and analysis and in particular sample-size adaptation, they move on to related topics in clinical pharmacology involving the use of cross-over designs. These include, but are not limited to, safety studies in Phase I, dose-response trials, drug interaction trials, food-effect and combination trials, QTc and other pharmacodynamic equivalence trials, proof-of-concept trials, dose-proportionality trials, and vaccines trials. This second edition addresses several recent developments in the field, including new chapters on adaptive bioequivalence studies, scaled average bioequivalence testing, and vaccine trials. Purposefully designed to be instantly applicable, Bioequivalence and Statistics in Clinical Pharmacology, Second Edition provides examples of SAS and R code so that the analyses described can be immediately implemented. The authors have made extensive use of the proc mixed procedures available in SAS.

Introduction to Mathematical Oncology presents biologically well-motivated and mathematically tractable models that facilitate both a deep understanding of cancer biology and better cancer treatment designs. It covers the medical and biological background of the diseases, modeling issues, and existing methods and their limitations. The authors introduce mathematical and programming tools, along with analytical and numerical studies of the models. They also develop new mathematical tools and look to future improvements on dynamical models. After introducing the general theory of medicine and exploring how mathematics can be essential in its understanding, the text describes well-known, practical, and insightful mathematical models of avascular tumor growth and mathematically tractable treatment models based on ordinary differential equations. It continues the topic of avascular tumor growth in the context of partial differential equation models by incorporating the spatial structure and physiological structure, such as cell size. The book then focuses on the recent active multi-scale modeling efforts on prostate cancer growth and treatment dynamics. It also examines more mechanistically formulated models, including cell quota-based population growth models, with applications to real tumors and validation using clinical data. The remainder of the text presents abundant additional historical, biological, and medical background materials for advanced and specific treatment modeling efforts. Extensively classroom-tested in undergraduate and graduate courses, this self-contained book allows instructors to emphasize specific topics relevant to clinical cancer biology and treatment. It can be used in a variety of ways, including a single-semester undergraduate course, a more ambitious graduate course, or a full-year sequence on mathematical oncology.

Private Security and the Investigative Process, Fourth Edition is fully updated and continues to provide complete coverage of the investigative process for private investigations by both individuals and in corporate security environments. This edition covers emerging technology, revised legal and practical considerations for conducting interviews, and new information on case evaluation. Written by a recognized expert in security, criminal justice, ethics, and the law-with over three decades of experience-the updated edition of this popular text covers concepts and techniques that can be applied to a variety of investigations including fraud, insurance, private, and criminal. It details the collection and preservation of evidence, the handling of witnesses, surveillance techniques, background investigations, and report writing. The book reflects best practices and includes tips for ensuring accurate and reliable private sector security investigations. This new edition includes: A new section on career opportunities in paths in the investigative field A rundown of the leading security Industry associations and professional standards being published Added discussion of observational interviews include current protocols analyzing data Details of the current legal implications for security surveillance and practices Advances in technology to thwart crime and fraud in retail and other business settings An entirely new section on e-records from criminal and civil judgments Authoritative, yet accessible, this book is one of the only textbooks dedicated to the subject. It also serves as an important reference for private investigators and security professionals. Complete with numerous forms, checklists, and web exercises, it provides the tools and understanding required to conduct investigations that are professional, ethical, and effective.

Luminescent materials with advanced performance are in the research hot spot with the recent technical developments of the display, lighting, and fluorescence labeling. Rare-earth-doped luminescent materials have been the focus of the research community owing to their wide applications in display devices, temperature sensors, solar cells, biomedical fields, optoelectronics, etc. This book covers the broad aspects of organic and inorganic materials based phosphors. The purpose of this book is to provide an up-to-date account of the present status and advancement of various techniques of synthesis of luminescent materials and their advanced applications in different areas. This book will cover all the experimental and theoretical approaches related to the rare-earth-doped luminescent materials. It also contains all the necessary information about the rare-earth-doped luminescent materials that were used in the past few years. In a nutshell, this book provides a unique platform to the newcomers who are planning to do research on rare-earthdoped luminescent materials as well as the researchers who are well established in this field.

This new volume, Promising Drug Molecules of Natural Origin, explores potential beneficial drug substances derived from nature. It presents the general principles, characteristics, evaluation techniques, and applications involved in drug molecules from natural sources, such as plants and marine life. With chapters from renowned experts from around the world, the chapters in this volume address the challenges of standardization of herbal medicines, methods of characterization of natural medicines and phyto-constituents, and quality control methods for herbal medicines. Several chapters in the book focus on the evolution of phyto-constituents in cancer therapeutics, while others deal with applications for other diseases, such as diabetes and neuroinflammatory disorders. The volume also specifically reviews heterocyclic drugs from plants. This volume will be a valuable resource for faculty and advanced students in pharmaceutics as well as researchers, scientists, and industry professionals in medicine and drug development.