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Books > Science & Mathematics > Biology, life sciences > General

Enzymes in the Valorization of Waste, Three Volume Set (Hardcover): Pradeep Verma Enzymes in the Valorization of Waste, Three Volume Set (Hardcover)
Pradeep Verma
R8,717 Discovery Miles 87 170 Ships in 12 - 17 working days

Divided into three volumes, Enzymes in Valorization of Waste covers enzymatic pre-treatment of waste for development of enzyme based biorefineries, enzymatic hydrolysis of waste for development of value-added products and next-Gen technological advances for sustainable biorefinery development. It covers enzyme assisted recovery of value-added compounds generated during the pre-treatment process, role of key enzymes used in the hydrolysis step of the biorefinery setup and modern next gen technologies for promoting the application of sustainable and greener enzymatic steps at industrial scale for development of futuristic and self-sustainable biorefinery. Features: Highlights mechanistic approach how the enzyme being able to regulate the delignification. Discusses advantages of the enzymatic delignification over other physical and chemical methods. Explores role of hydrolyzing enzymes in breakdown and transformation of biomass hydrolysis. Discusses potential of auxiliary enzyme (LPMO's) for enhancing hydrolysis potential. Includes all the modern day technologies that can be potentially used in enzyme based biorefinery conversion of wastes to value added products. This book aims at Graduate students, Researchers in Biochemical Engineering, Environmental Science, Wastewater Treatment, Biotechnology, Applied Microbiology, Biomass Based Biorefinery, Biochemistry, Green Chemistry, Sustainable Development, Waste Treatment, Enzymology, Microbial Biotechnology, and Waste Valorization.

Case Studies in Bayesian Methods for Biopharmaceutical CMC (Hardcover): Paul Faya, Tony Pourmohamad Case Studies in Bayesian Methods for Biopharmaceutical CMC (Hardcover)
Paul Faya, Tony Pourmohamad
R4,081 Discovery Miles 40 810 Ships in 12 - 17 working days

The subject of this book is applied Bayesian methods for chemistry, manufacturing, and control (CMC) studies in the biopharmaceutical industry. The book has multiple authors from industry and academia, each contributing a case study (chapter). The collection of case studies covers a broad array of CMC topics, including stability analysis, analytical method development, specification setting, process development and optimization, process control, experimental design, dissolution testing, and comparability studies. The analysis of each case study includes a presentation of code and reproducible output. This book is written with an academic level aimed at practicing nonclinical biostatisticians, most of whom have graduate degrees in statistics. * First book of its kind focusing strictly on CMC Bayesian case studies * Case studies with code and output * Representation from several companies across the industry as well as academia * Authors are leading and well-known Bayesian statisticians in the CMC field * Accompanying website with code for reproducibility * Reflective of real-life industry applications/problems

Enzymes in the Valorization of Waste - Enzymatic Hydrolysis of Waste for Development of Value-added Products (Hardcover):... Enzymes in the Valorization of Waste - Enzymatic Hydrolysis of Waste for Development of Value-added Products (Hardcover)
Pradeep Verma
R3,483 Discovery Miles 34 830 Ships in 12 - 17 working days

Explores role of hydrolysing enzymes in breakdown and transformation of biomass hydrolysis Discusses potential of auxiliary enzyme (LPMO's) for enhancing hydrolysis potential Covers recent development in the field of enzymatic-assisted hydrolysis of waste for conversion of waste to value-added products Deliberates all possible products that can be generated from enzymatic hydrolysis of waste and their possible utilization Elucidate the limitations and advantages of enzyme-based hydrolysis and possible strategies for moving from laboratory to the large-scale industries

Enzymes in the Valorization of Waste - Next-Gen Technological Advances for Sustainable Development of Enzyme based Biorefinery... Enzymes in the Valorization of Waste - Next-Gen Technological Advances for Sustainable Development of Enzyme based Biorefinery (Hardcover)
Pradeep Verma
R3,482 Discovery Miles 34 820 Ships in 12 - 17 working days

Explores all the modern-day technologies that can be potentially used in enzyme-based biorefinery conversion of wastes to value- added products. Covers technological, economic and environmental assessments of enzyme-based biorefinery prospects Deliberates all possible products that can be generated from wastes including biofuel and essential chemicals Illustrates techniques for enhanced yield and properties to be used in various industrial applications Reviews advanced information of relevant sources and mechanism of enzymes

ISE Prescott's Principles of Microbiology (Paperback, 2nd edition): Joanne Willey, Christopher J Woolverton, Linda Sherwood ISE Prescott's Principles of Microbiology (Paperback, 2nd edition)
Joanne Willey, Christopher J Woolverton, Linda Sherwood
R1,794 Discovery Miles 17 940 Ships in 12 - 17 working days

Prescott's Principles of Microbiology provides a balanced, comprehensive introduction to all major areas of microbiology. Because of this balance, Prescott's Principles of Microbiology is appropriate for microbiology majors and mixed majors courses. The authors have focused on readability, artwork, and the integration of several key themes, including evolution, ecology and diversity, throughout the text, making an already superior text even better.

Handbook of Chemical and Biological Warfare Agents, Volume 2 - Nonlethal Chemical Agents and Biological Warfare Agents... Handbook of Chemical and Biological Warfare Agents, Volume 2 - Nonlethal Chemical Agents and Biological Warfare Agents (Hardcover, 3rd edition)
D. Hank Ellison
R2,127 Discovery Miles 21 270 Ships in 12 - 17 working days

The Handbook of Chemical and Biological Warfare Agents, Volume 2: Pathogens, Mid-Spectrum, and Incapacitating Agents, Third Edition provides rapid access to key data to response professionals and decision-makers on a broad range of agents and pathogens. This volume presents information on a wide range of chemical and biological agents. Chemical agents detailed in this volume are those that were developed specifically for their non-lethal potential. The biological agents described are militarily significant pathogens that could be weaponized to pose a threat to people, animals, or crops and other agricultural interests. Mid-spectrum agents, materials that do not fit clearly into either the Chemical or the Biological Weapons Conventions, include toxins and bioregulators. Entomological agents, the final class of agents discussed in volume, are arthropods that could pose a significant threat to a country's agriculture infrastructure and be used to devastate its economy. They were proposed for inclusion in the Biological Weapons Convention but never adopted. In addition to a discussion of each of these classes of agents, coverage includes detailed information on a broad spectrum of individual agents that have been used on the battlefield, stockpiled as weapons, used or threatened to be used by terrorists, or have been otherwise assessed by qualified law enforcement and response organizations and determined to be agents of significant concern. The information presented in this edition has been updated and expanded to contain more information on toxicology, health effects, presentation of diseases, advances in medical care and treatment, as well as protective actions needed at the scene of an incident. Key Features: Focuses on the key information needed during an emergency response Provides updated toxicology, exposure hazards, physical-chemical data, and treatment of casualties Profiles the presentation of diseases in people, animals and plants Presents updated protective action distances, decontamination, and remediation information All data compiled is gathered from numerous sources and arranged into the current, easy-to-access format. In order to ensure accuracy, all data has been cross-checked over the widest variety of military, scientific and medical sources available. The Handbook of Chemical and Biological Warfare Agents, Volume 2: Pathogens, Mid-Spectrum, and Incapacitating Agents, Third Edition remains the gold-standard reference detailing the widest variety of military, scientific, and medical sources available.

Biodiversity, Food and Nutrition - A New Agenda for Sustainable Food Systems (Hardcover): Danny Hunter, Teresa Borelli, Eliot... Biodiversity, Food and Nutrition - A New Agenda for Sustainable Food Systems (Hardcover)
Danny Hunter, Teresa Borelli, Eliot Gee
R3,920 Discovery Miles 39 200 Ships in 12 - 17 working days

This book examines the challenges and impacts of poor diets and nutrition from current food systems and the potential contribution of biodiversity and ecosystem services in addressing these problems. There is a strong need for a multi-level, cross-sectoral approach that connects food biodiversity conservation and sustainable use to address critical problems in our current food systems, including malnutrition. Building on research from the Biodiversity for Food and Nutrition Project (BFN), which aims to better link biodiversity, diets and nutrition, the book presents a multi-country, cross-sectoral analysis of initiatives that have promoted local food biodiversity in four countries: Brazil, Kenya, Turkey and Sri Lanka. This book offers a comprehensive summary of the BFN Project results in each of the four countries along with lessons learned and how this work could be upscaled or applied in other regions. It argues that the strategic promotion and use of food biodiversity is critical in uniting attempts to address conservation, nutrition and livelihood concerns. The book is structured around chapters and case studies encompassing the BFN Project with specific experiences related by partners who played key roles in the work being done in each country. By offering a comparative view capable of furthering dialogue between the respective countries, it is also meant to connect the individual cases for a "greater than the sum of its parts" effect. This means consideration of how localized activities can be adapted to more countries and regions. Therefore, the book addresses global issues with a foot planted firmly in the grounded case study locations. This book will be of great interest to policymakers, practitioners and NGOs working on food and nutrition, as well as students and scholars of agriculture, food systems and sustainable development.

Pharmaceutical Drug Product Development and Process Optimization - Effective Use of Quality by Design (Hardcover): Sarwar Beg,... Pharmaceutical Drug Product Development and Process Optimization - Effective Use of Quality by Design (Hardcover)
Sarwar Beg, Mahfoozur Rahman, Majed Al Robaian, Syed Sarim Imam, Nabil Alruwaili, …
R3,966 Discovery Miles 39 660 Ships in 12 - 17 working days

Pharmaceutical manufacturers are constantly facing quality crises of drug products, leading to an escalating number of product recalls and rejects. Due to the involvement of multiple factors, the goal of achieving consistent product quality is always a great challenge for pharmaceutical scientists. This volume addresses this challenge by using the Quality by Design (QbD) concept, which was instituted to focus on the systematic development of drug products with predefined objectives to provide enhanced product and process understanding. This volume presents and discusses the vital precepts underlying the efficient, effective, and cost effective development of pharmaceutical drug products. It focuses on the adoption of systematic quality principles of pharmaceutical development, which is imperative in achieving continuous improvement in end-product quality and also leads to reducing cost, time, and effort, while meeting regulatory requirements. The volume covers the important new advances in the development of solid oral dosage forms, modified release oral dosage forms, parenteral dosage forms, semisolid dosage forms, transdermal drug, delivery systems, inhalational dosage forms, ocular drug delivery systems, nanopharmaceutical products, and nanoparticles for oral delivery.

Guide to Simulation-Based Disciplines - Advancing Our Computational Future (Hardcover, 1st ed. 2017): Saurabh Mittal, Umut... Guide to Simulation-Based Disciplines - Advancing Our Computational Future (Hardcover, 1st ed. 2017)
Saurabh Mittal, Umut Durak, Tuncer I. Oren
R4,344 R3,889 Discovery Miles 38 890 Save R455 (10%) Ships in 12 - 17 working days

This invaluable text/reference reviews the state of the art in simulation-based approaches across a wide range of different disciplines, and provides evidence of using simulation-based approaches to advance these disciplines. Highlighting the benefits that simulation can bring to any field, the volume presents case studies by the leading experts from such diverse domains as the life sciences, engineering, architecture, arts, and social sciences. Topics and features: includes review questions at the end of every chapter; provides a broad overview of the evolution of the concept of simulation, stressing its importance across numerous sectors and disciplines; addresses the role of simulation in engineering design, and emphasizes the benefits of integrating simulation into the systems engineering paradigm; explains the relation of simulation with Cyber-Physical Systems and the Internet of Things, and describes a simulation infrastructure for complex adaptive systems; investigates how simulation is used in the Software Design Life Cycle to assess complex solutions, and examines the use of simulation in architectural design; reviews the function and purpose of simulation within the context of the scientific method, and its contribution to healthcare and health education training; discusses the position of simulation in research in the social sciences, and describes the simulation of service systems for simulation-based enterprise management; describes the role of simulation in learning and education, as well as in in military training. With its near-exhaustive coverage of disciplines, this comprehensive collection is essential reading for all researchers, practitioners and students seeking insights into the use of various modeling paradigms and the need for robust simulation infrastructure to advance their field into a computational future.

Cyber Investigations (Paperback): A Arnes Cyber Investigations (Paperback)
A Arnes
R1,922 Discovery Miles 19 220 Ships in 12 - 17 working days

CYBER INVESTIGATIONS A classroom tested introduction to cyber investigations with real-life examples included Cyber Investigations provides an introduction to the topic, an overview of the investigation process applied to cyber investigations, a review of legal aspects of cyber investigations, a review of Internet forensics and open-source intelligence, a research-based chapter on anonymization, and a deep-dive in to multimedia forensics. The content is structured in a consistent manner, with an emphasis on accessibility for students of computer science, information security, law enforcement, and military disciplines. To aid in reader comprehension and seamless assimilation of the material, real-life examples and student exercises are provided throughout, as well as an Educational Guide for both teachers and students. The material has been classroom-tested and is a perfect fit for most learning environments. Written by a highly experienced author team with backgrounds in law enforcement, academic research, and industry, sample topics covered in Cyber Investigations include: The cyber investigation process, including developing an integrated framework for cyber investigations and principles for the integrated cyber investigation process (ICIP) Cyber investigation law, including reasonable grounds to open a criminal cyber investigation and general conditions for privacy-invasive cyber investigation methods Perspectives of internet and cryptocurrency investigations, including examples like the proxy seller, the scammer, and the disgruntled employee Internet of things (IoT) investigations, including types of events leading to IoT investigations and new forensic challenges in the field Multimedia forensics facilitates the understanding of the role of multimedia in investigations, including how to leverage similarity matching, content-based tracing, and media metadata. Anonymization networks discusses how such networks work, and how they impact investigations? It addresses aspects of tracing, monitoring, evidence acquisition, de-anonymization, and large investigations Based on research, teaching material, experiences, and student feedback over several years, Cyber Investigations is ideal for all students and professionals in the cybersecurity industry, providing comprehensive subject coverage from faculty, associates, and former students of cyber security and digital forensics at the Norwegian University of Science and Technology (NTNU).

Master Farmer - Teaching Small Farmers Management (Paperback): Bruce M. Lansdale Master Farmer - Teaching Small Farmers Management (Paperback)
Bruce M. Lansdale
R1,167 Discovery Miles 11 670 Ships in 12 - 17 working days

The story of postwar Greece holds invaluable lessons for many developing countries today. In 1947 Greece had just emerged from a decade of war and strife; its villagers were demoralized and fleeing rural life for the cities; and its farms were unable to produce adequate crops to feed its people. In less than forty years Greece has become a major ex

A-Level Biology: Aqa Year 2 Complete Revision & Practice with Online Edition (Mixed media product): CGP Books A-Level Biology: Aqa Year 2 Complete Revision & Practice with Online Edition (Mixed media product)
CGP Books; Edited by CGP Books
R363 Discovery Miles 3 630 Ships in 9 - 15 working days

"There's no better way to learn Year 2 of the AQA A-Level Biology course than with this new and improved CGP Complete Revision & Practice book. It's perfect for reference throughout the year, and preparing for the final exams! It has straightforward study notes, helpful examples and full-colour diagrams. We've included more challenging exam practice than ever before with plenty of practice questions and exam-style questions (with detailed answers) for every topic - plus a section of mixed (synoptic) practice testing different parts of the course. To round things off there are sections of in-depth advice on Practical Skills and how to pick up top marks in the exams. There's even a free Online Edition of the whole book - just use the code printed inside the book to access it on your PC, Mac or tablet. For even more practice don't miss CGP's Year 2 of A-Level Biology Exam Practice Workbook (9781782949091). "

Genome Engineering for Crop Improvement (Hardcover): S. Upadhyay Genome Engineering for Crop Improvement (Hardcover)
S. Upadhyay
R4,432 Discovery Miles 44 320 Ships in 12 - 17 working days

In recent years, significant advancements have been made in the management of nutritional deficiency using genome engineering--enriching the nutritional properties of agricultural and horticultural crop plants such as wheat, rice, potatoes, grapes, and bananas. To meet the demands of the rapidly growing world population, researchers are developing a range of new genome engineering tools and strategies, from increasing the nutraceuticals in cereals and fruits, to decreasing the anti-nutrients in crop plants to improve the bioavailability of minerals and vitamins. Genome Engineering for Crop Improvement provides an up-to-date view of the use of genome editing for crop bio-fortification, improved bioavailability of minerals and nutrients, and enhanced hypo-allergenicity and hypo-immunogenicity. This volume examines a diversity of important topics including mineral and nutrient localization, metabolic engineering of carotenoids and flavonoids, genome engineering of zero calorie potatoes and allergen-free grains, engineering for stress resistance in crop plants, and more. Helping readers deepen their knowledge of the application of genome engineering in crop improvement, this book: Presents genetic engineering methods for developing edible oil crops, mineral translocation in grains, increased flavonoids in tomatoes, and cereals with enriched iron bioavailability Describes current genome engineering methods and the distribution of nutritional and mineral composition in important crop plants Offers perspectives on emerging technologies and the future of genome engineering in agriculture Genome Engineering for Crop Improvement is an essential resource for academics, scientists, researchers, agriculturalists, and students of plant molecular biology, system biology, plant biotechnology, and functional genomics.

An Introduction to Molecular Biotechnology - Fundamentals, Methods and Applications 3e (Paperback, 3rd Edition): M Wink An Introduction to Molecular Biotechnology - Fundamentals, Methods and Applications 3e (Paperback, 3rd Edition)
M Wink
R2,406 Discovery Miles 24 060 Ships in 12 - 17 working days

Die Neuauflage dieses uberaus renommierten Lehrbuchs wurde als Antwort auf die rasanten Fortschritte in dem Fachgebiet vollstandig aktualisiert und prasentiert neue leistungsstarke Methoden und Konzepte in der Biotechnologie, u.a. Genome Editing, reprogrammierte Stammzellen und personalisierte Medizin. Auf eine Einfuhrung in die Grundlagen der Molekular- und Zellbiologie folgt eine Beschreibung der Standardverfahren, darunter Aufreinigung und Analyse von Biomolekulen, Verfahren der Klonierung, Gen-Expressionssysteme, Methoden des Genome Editing, Protein-Labeling und In-situ-Verfahren, Standard- und hochaufloesende Mikroskopie. Der dritte Teil legt den Schwerpunkt auf wichtige Forschungs- und Anwendungsgebiete, von der funktionalen Genomik, Proteomik und Bioinformatik bis hin zu Drug Targeting, rekombinante Antikoerper und Systembiologie. Der letzte Teil wirft einen Blick auf Unternehmen der Biotechnologie und untersucht Fragestellungen des geistigen Eigentums, den Rechtsrahmen fur pharmazeutische Produkte und das Zusammenspiel von Startup- und groesseren Unternehmen. Die Inhalte sind durchgangig uberaus ansprechend illustriert, mit Hunderten von farbigen Diagrammen und Fotos. Dieses Lehrbuch vermittelt Studenten und Berufspraktikern der Biowissenschaften, Pharmazie und Biochemie alles Wissenswerte rund um die molekulare Biotechnologie.

Biomarker Analysis in Clinical Trials with R (Hardcover): Nusrat Rabbee Biomarker Analysis in Clinical Trials with R (Hardcover)
Nusrat Rabbee
R3,184 Discovery Miles 31 840 Ships in 12 - 17 working days

The world is awash in data. This volume of data will continue to increase. In the pharmaceutical industry, much of this data explosion has happened around biomarker data. Great statisticians are needed to derive understanding from these data. This book will guide you as you begin the journey into communicating, understanding and synthesizing biomarker data. -From the Foreword, Jared Christensen, Vice President, Biostatistics Early Clinical Development, Pfizer, Inc. Biomarker Analysis in Clinical Trials with R offers practical guidance to statisticians in the pharmaceutical industry on how to incorporate biomarker data analysis in clinical trial studies. The book discusses the appropriate statistical methods for evaluating pharmacodynamic, predictive and surrogate biomarkers for delivering increased value in the drug development process. The topic of combining multiple biomarkers to predict drug response using machine learning is covered. Featuring copious reproducible code and examples in R, the book helps students, researchers and biostatisticians get started in tackling the hard problems of designing and analyzing trials with biomarkers. Features: Analysis of pharmacodynamic biomarkers for lending evidence target modulation. Design and analysis of trials with a predictive biomarker. Framework for analyzing surrogate biomarkers. Methods for combining multiple biomarkers to predict treatment response. Offers a biomarker statistical analysis plan. R code, data and models are given for each part: including regression models for survival and longitudinal data, as well as statistical learning models, such as graphical models and penalized regression models.

Model-Assisted Bayesian Designs for Dose Finding and Optimization - Methods and Applications (Hardcover): Ying Yuan, Ruitao... Model-Assisted Bayesian Designs for Dose Finding and Optimization - Methods and Applications (Hardcover)
Ying Yuan, Ruitao Lin, J. Jack Lee
R2,657 Discovery Miles 26 570 Ships in 12 - 17 working days

Features Represents the first book to provide comprehensive coverage of model-assisted designs for various types of dose-finding and optimization clinical trials Describes the up-to-date theory and practice for model-assisted designs Presents many practical challenges and issues arising from early-phase clinical trials Illustrates with many real trial applications Offers numerous tips and guidance on designing dose finding and optimization trials Provides step-by-step illustration of using software to design trials Develops a companion website (www.trialdesign.org) to provide easy-to-use software to assist learning and implementing model-assisted designs.

Blood (Paperback): Iosifina Foskolou, Martin Jones Blood (Paperback)
Iosifina Foskolou, Martin Jones
R570 R537 Discovery Miles 5 370 Save R33 (6%) Ships in 12 - 17 working days

Blood is life, its complex composition is finely attuned to our vital needs and functions. Blood can also signify death, while 'bloody' is a curse. Arising from the 2021 Darwin College Lectures, this volume invites leading thinkers on the subject to explore the many meanings of blood across a diverse range of disciplines. Through the eyes of artist Marc Quinn, the paradoxical nature of blood plays with the notion of self. Through those of geneticist Walter Bodmer, it becomes a scientific reality: bloodlines and diaspora capture our notions of community. The transfer of blood between bodies, as Rose George relates, can save lives, or as we learn from Claire Roddie can cure cancer. Tim Pedley and Stuart Egginton explore the extraordinary complexity of blood as a critical biological fluid. Sarah Read examines the intimate connection between blood and womanhood, as Carol Senf does in her consideration of Bram Stoker's novel Dracula.

Higher Biology - Practise and Learn Sqa Exam Topics (Paperback, Edition): John Di Mambro, Stuart White, Leckie Higher Biology - Practise and Learn Sqa Exam Topics (Paperback, Edition)
John Di Mambro, Stuart White, Leckie 1
R309 R232 Discovery Miles 2 320 Save R77 (25%) Ships in 12 - 17 working days

Exam Board: SQA Level: Higher Subject: Biology First Teaching: 2014, First Exam: 2015 Masses of practice questions for every topic on the curriculum. Essential extra questions for every topic on the curriculum, to reinforce learning and build exam confidence. It can be used either alongside the N5 Biology Student Book or as a flexible standalone resource - for homework, independent study or exam practice. Included in this book: Questions for every topic on the curriculum, with more of the tricky ones Example answers with workings-out help explain difficult concepts Hints and tips throughout give practical advice about the different kinds of question Answers can be downloaded from www.collins.co.uk/pages/scottish-curriculum-free-resources

Federal Influences on Biomedical Technology Innovation (Paperback): Lilly B Gardner Federal Influences on Biomedical Technology Innovation (Paperback)
Lilly B Gardner
R731 R511 Discovery Miles 5 110 Save R220 (30%) Ships in 12 - 17 working days

Published in 1994, this book examines a small segment of the medical technology innovation process to characterize the manner in which the federal government influences small business-based investigators to participate or withdraw from the medical technology innovation process. It provides an historical account of the federal government's involvement in biomedical technology research and development, and traces the social and economic significance of this involvement.

A-Level Biology: Edexcel a Year 1 & 2 Complete Revision & Practice with Online Edition (Paperback, Online Ed): CGP Books A-Level Biology: Edexcel a Year 1 & 2 Complete Revision & Practice with Online Edition (Paperback, Online Ed)
CGP Books; Edited by CGP Books
R655 Discovery Miles 6 550 Ships in 9 - 15 working days

This clear, concise Complete Revision & Practice book from CGP is a perfect way to prepare for the Edexcel A A-Level Biology exams - it covers every topic from both years of the course. It's fully up-to-date for the new exam specifications for 2015 and beyond, with straightforward explanations, helpful examples and full-colour diagrams throughout. Practice questions and exam-style questions (with answers) are included for every topic, and the book is rounded off with a section of in-depth advice on Practical Skills. And finally, a free Online Edition of the whole book is included - just use the code printed inside the book to access it on your PC, Mac or tablet!

Implantable Medical Devices and Healthcare Affordability - Exposing the Spiderweb (Paperback): Mark C. West, Michael Georgulis Implantable Medical Devices and Healthcare Affordability - Exposing the Spiderweb (Paperback)
Mark C. West, Michael Georgulis
R948 Discovery Miles 9 480 Ships in 9 - 15 working days

The United States spends more than 17% of its GDP on health care, while other developed countries throughout the world average 8.7% of GDP on healthcare expenditures. By 2028, that percentage in the United States is projected to be 19.7% of GDP. Yet all this spending apparently doesn't equate to value, quality, or performance. Among 11 high-income countries the United States healthcare industry ranked last during the past seven years in four key performance categories: administrative efficiency, access to care, equity, and healthcare outcomes. This book presents the implantable medical device (IMD) supply chain ecosystem as a microcosm of how these challenges of affordability and healthcare outcomes are created and are allowed to fester. The IMD Spiderweb, as the authors call it, is exposed as an example of how a wide range of participants-including physicians, health system CEOs, group purchasing organizations, health insurance companies and supply chain executives-become ensnared in a web designed to benefit only one player. The book also details the affordability challenges in the industry caused by the past and current IMD ecosystem and presents a model for meeting those challenges. The result is that the true cost of IMDs is hidden, while hospitals and health systems in the United States pay as much as six times more for some IMDs as their counterparts do in Europe, and prices for the same model of a particular IMD vary wildly even among different U.S. hospitals. While there is a fascination with the latest and greatest device there is also a shroud around visibility into how these products-which include cardiac rhythm management devices such as pacemakers and orthopedic implants such as knees and hips-have performed and are likely to perform in patients. The costs continue to rise not only in healthcare expenditures, but also in death and disability. The IMD spiderweb is presented as a prime lesson in the challenges in healthcare affordability and outcomes that occur throughout the entire healthcare industry. It is also put forward as an opportunity. The story behind how these challenges arose and are deepened by the ecosystem provides a foundation for solutions.

Manual of Crime Scene Investigation (Hardcover): Anna Barbaro, Amarnath Mishra Manual of Crime Scene Investigation (Hardcover)
Anna Barbaro, Amarnath Mishra
R3,782 Discovery Miles 37 820 Ships in 12 - 17 working days

Over the past several years, myriad manuals on crime scene investigations have been published with each focusing on select, or partial, aspects of the investigation. Crime scene investigation, done right, is a multi-faceted process that requires various forms of evidence to be collected, examined, and analyzed. No book available has addressed procedures to present global best practices by assembling a collection of international experts to address such topics. Manual of Crime Scene Investigation is a comprehensive collaboration of experts writing on their particular areas of expertise as relates to crime scenes, evidence, and crime scene investigation. The book outlines best practices in the field, incorporating the latest technology to collect, preserve, and enhance evidence for appropriate analysis. Various types of forensic evidence are addressed, covering chain of custody, collection, and utility of such evidence in casework, investigations, and for use in court. The approach, and use of international contributor experts, will appeal to a broad audience and be of use to forensic practitioners, and the forensic science community worldwide. Key features: * Assembles an international team of contributing author experts to present the latest developments in their crime scene field of specialty * Examines global best practices and what are consistently the most reliable tactics and approach to crime scene evidence collection, preservation, and investigation * Provides numerous photographs and diagrams to clearly illustrate chapter concepts Manual of Crime Scene Investigation serves as a vital resource to professionals in police science and crime scene investigations, private forensic institutions, and academics researching how better real-world application of techniques can improve the reliability and utility of evidence upon forensic and laboratory analysis.

Molecular Imprinting of Polymers (Paperback): Sergey Piletsky Molecular Imprinting of Polymers (Paperback)
Sergey Piletsky
R1,764 Discovery Miles 17 640 Ships in 12 - 17 working days

One of Nature's most important talents is evolutionary development of systems capable of molecular recognition: distinguishing one molecule from another. Molecular recognition is the basis for most biological processes, such as ligandreceptor binding, substrate-enzyme reactions and translation and transcription of the genetic code and is therefore of universal interest. Over the past four decades, researchers have been inspired by Nature to produce biomimetic materials with molecular recognition properties, by design rather than by evolution. A particularly exciting area of biomimetics is Molecular Imprinting, which can be defined as process of template-induced formation of specific recognition sites (binding or catalytic) in a material where the template directs the positioning and orientation of the material's structural components by a self-assembling mechanism. The material itself could be oligomeric (the typical example is DNA replication process), polymeric (organic MIPs and inorganic imprinted silica gels) or 2-dimensional surface assembly (grafted monolayers). Essentially the current progress in the field of molecular imprinting is a result of fundamental achievements made by more than a hundred groups working in the areas of non-covalent and reversible covalent imprinting. The goal of this title is to capture this momentum and publish a new book that will reflect the current situation in this rapidly evolving technology. Very few of the tens of reviews already published on this subject present a critical analysis of the technological aspects of molecular imprinting. Leaders in this field have been approached with requests to provide their views and analyses of specific areas of design, characterization and application of these polymers. The main body of Molecular Imprinting of Polymers starts with chapters covering polymer design, synthesis, and characterization that are prepared by well-recognized experts such as Andrew Mayes and Natalia Perez-Moral, Claud

Waste Management (Paperback): A.L. Juhasz Waste Management (Paperback)
A.L. Juhasz
R1,784 Discovery Miles 17 840 Ships in 12 - 17 working days

This book focuses on the impact of waste disposal to land, providing an outline of the underpinning knowledge of processes associated with contaminant sorption, transport, and plant uptake. It presents case studies highlighting waste management technologies used in the Australasia-Pacific region.

Handbook of Biogeneric Therapeutic Proteins - Regulatory, Manufacturing, Testing, and Patent Issues (Paperback): Sarfaraz K.... Handbook of Biogeneric Therapeutic Proteins - Regulatory, Manufacturing, Testing, and Patent Issues (Paperback)
Sarfaraz K. Niazi
R1,767 Discovery Miles 17 670 Ships in 12 - 17 working days

More than 20 billion dollars worth of biopharmaceuticals are scheduled to go off-patent by 2006. Given the strong political impetus and the development of technological tools that can answer the questions regulatory authorities may raise, it is inevitable that the FDA and EMEA will allow biogeneric or biosimilar products. Even with all the regulatory wrinkles yet to be ironed out, generic or similar biological products are soon to become a reality. Handbook of Biogeneric Therapeutic Proteins is the first book to review and analyze the status of biotechnology, regulatory environment, manufacturing methodologies, testing requirements and intellectual property issues. The book provides complete and thorough coverage of the regulatory and technological challenges of developing generic therapeutic proteins and how to prepare detailed regulatory and manufacturing plans and policies. The author includes information on establishing a manufacturing system, securing regulatory approval, and setting up facilities to manufacture raw materials and prepare finished products. He also supplies details about the Chemistry, Manufacturing, and Controls (CMC) section of the FDA's New Drug Application for Biological Products. In brief, the book supplies everything a manufacturer would need to plan the development of biogeneric products and complete the process of regulatory filing. Waiting for the FDA to issue guidelines is a mistake. The scramble to catch up could leave your company way behind in the game. Your organization needs to begin developing and characterizing genetically modified cells now and to complete initial GMP production runs through a CRO to get ready for the newer testing the FDA might impose. Packed with tables and figures that provide speedy access to precise, timely data, including full formulation details on all FDA approved biological product, this book contains a broad range of resource materials about suppliers, manufacturers, and testing faciliti

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