Ancient therapeutic systems have played a tremendous role in health preservation all around the globe for thousands of years; even the earliest humans on earth had used these approaches along with simple surgical procedures for the betterment of their health. Complementary and Alternative Medicinal Approaches for Enhancing Immunity examines various aspects of health and diseases and the importance of basic but essential factors for the preservation of health and management of diseases. Concisely written, the author discusses ancient ways to enhance self-healing abilities and stimulate the immune system such as, fasting, meditation, acupuncture, cupping therapy, balneotherapy and aromatherapy. The importance of nutrition and diet is also examined as it plays a crucial role in the prevention and causation of diseases. Additional features include: Discusses how the integration of various CAM modalities helps in enhancing self-healing abilities and boosts the human immune system. Contains various topics from different systems of medicines that are taught widely as individual courses or discussed broadly in several institutes. Reviews Eastern pharmacotherapy and how using certain herbs, minerals, and animal-based products aids in maintaining health and alleviating diseases. Using evidence-based knowledge taken from ancient literature and recently published articles, this book will inform readers on the importance of holistic health approaches and some ancient treatment modalities that enhance the immune system to combat diseases.

Presents short topics tied to numerical or conceptual ideas, reinforced with worked examples and questions Retaining the user-friendly style of the first edition, this text is designed to eliminate the knowledge gap for those life sciences students who have not studied chemistry at an advanced level. It contains new chapters on - * Water, covering the mole concept and colloids * Gases, discussing pressure, gas laws, partial pressure, solubility of gases, and diffusion * Metals in biology, including properties, oxygen carriers, biocatalysis, charge carriers, and toxicity The authors divide their analysis of carbon compounds into two chapters. One focuses exclusively on aliphatic carbon compounds, while the other provides a greatly expanded exploration of aromatic carbon compounds, isomerism, amines and amino acids, including benzene, aromaticity, types of isomerism, and absolute configuration. With a current examination of organic and biological reactions, this instructional volume also features end-of-chapter questions and provides a solutions manual for qualified instructors. Key Features: Focuses on the particular aspects of chemistry that underpin biochemical and biomedical studies Includes new chapters on emerging topics of interest Offers a sequence of short topics with numerical or conceptual ideas supported by worked examples and questions within the text Provides a solutions manual for qualified instructors

Exam Board: Edexcel Level: A level Subject: Science / Biology First teaching: September 2015 First exams: June 2017 Revise smart and save! Designed for hassle-free classroom and independent study, our Revision Guides are designed to complement the Student Books with a range of specially designed features such as: One-topic-per-page format Worked examples with exemplar answers 'Now Try This' practice questions Knowledge checks and skills checks Includes FREE online edition! With a one-to-one page correspondence between this Revision Guide and the companion Edexcel AS/A level Biology Revision Workbook, the hugely popular REVISE series offers the best value available for A level students.

The large amount of information on fish reproduction available is not always readily accessible to all interested parties. Written to appeal to aquaculturalists, conservation managers, and scientific researchers, Methods in Reproductive Aquaculture provides an overview of available techniques and addresses ways to improve depleted stocks of endangered fish and other species. The book focuses on gamete quality and management, exploring new objectives and areas of application and research, and new tools to deal with some aspects in reproduction of aquatic species. It begins with an examination of basic methods and techniques for gamete extraction, mainly sperm collection and egg stripping in different species, then describes techniques of spawning stimulation in males and females. The volume then highlights sperm and egg quality evaluation and considers sperm analysis from a practical broodstock management point of view and in the selection of appropriate breeders. The book goes on to discuss techniques used for artificial fertilization and the procedures for obtaining modified offspring. It introduces cryopreservation procedures for sperm, oocytes, and embryos, then discusses the materials and facilities required for gamete preparation and freezing-thawing procedures. The book concludes with an extensive section detailing sperm cryopreservation protocols for fifty-six marine and freshwater species. Unique in its focus on both marine and freshwater aquaculture of fishes, the book provides information on endangered, highly profitable species for aquaculture or fisheries and species with high potential in laboratory research. Presenting the available information in an easily understandable way, this is not merely a techniques book, but also a complete guide to fish reproduction, gamete quality, and management.

Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbruck Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.

Geospatial health data are essential to inform public health and policy. These data can be used to quantify disease burden, understand geographic and temporal patterns, identify risk factors, and measure inequalities. Geospatial Health Data: Modeling and Visualization with R-INLA and Shiny describes spatial and spatio-temporal statistical methods and visualization techniques to analyze georeferenced health data in R. The book covers the following topics: Manipulating and transforming point, areal, and raster data, Bayesian hierarchical models for disease mapping using areal and geostatistical data, Fitting and interpreting spatial and spatio-temporal models with the integrated nested Laplace approximation (INLA) and the stochastic partial differential equation (SPDE) approaches, Creating interactive and static visualizations such as disease maps and time plots, Reproducible R Markdown reports, interactive dashboards, and Shiny web applications that facilitate the communication of insights to collaborators and policymakers. The book features fully reproducible examples of several disease and environmental applications using real-world data such as malaria in The Gambia, cancer in Scotland and USA, and air pollution in Spain. Examples in the book focus on health applications, but the approaches covered are also applicable to other fields that use georeferenced data including epidemiology, ecology, demography or criminology. The book provides clear descriptions of the R code for data importing, manipulation, modelling, and visualization, as well as the interpretation of the results. This ensures contents are fully reproducible and accessible for students, researchers and practitioners.

Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of efficacy and safety of drug candidates through preclinical testing. This book also greatly expands the focus on the clinical pharmacology, regulatory, and business aspects of bringing new drugs to the market and offers coverage of essential topics for companies involved in drug development. Historical perspectives and predicted trends are also provided. Features: Highlights emerging scientific fields relevant to drug discovery such as the microbiome, nanotechnology, and cancer immunotherapy; and novel research tools such as CRISPR and DNA-encoded libraries Case study detailing the discovery of the anti-cancer drug, lorlatinib Venture capitalist commentary on trends and best practices in drug discovery and development Comprehensive review of regulations and their impact on drug development, highlighting special populations, orphan drugs, and pharmaceutical compounding Multidiscipline functioning of an Academic Research Enterprise, plus a chapter on Ethical Concerns in Research Contributions by 70+ experts from industry and academia specialists who developed and are practitioners of the science and business

Dive into the most common statistical tests and software packages used for scientific data analysis and interpretation In Essential Statistics For Bioscientists, experienced university and bioscientist Dr Mohammed Meah delivers easy access to statistical analysis and data presentation. It is a great resource for students in the field of life and health sciences to conceptualize, analyze, and present data. This book uses three popular and commonly used statistics softwares--Microsoft Excel, Graphpad Prism, and SPSS--and offers clear, step-by-step instructions for essential data analysis and graphical/tabular display of data. Beginning with fundamental statistics terminology and concepts, including data types, descriptive statistics (central and spread of data), exploratory statistics (graphical display) and inferential statistics (hypothesis testing and correlation), the content gradually builds in complexity, explaining which statistical test is best suited and how to perform it. A thorough introduction to basic statistical terms and building up to an advanced level of statistical application- ideal for those new to study of statistics Extensive application of three popular software packages- Microsoft Excel, Graphpad Prism and SPSS Numerous hands-on examples of performing data analysis using Microsoft Excel, Graphpad Prism, and SPSS Considers the limitations and errors of statistical analysis Essential reading for those designing and planning a research project in Biosciences Perfect for undergraduate students in the life and health sciences, Essential Statistics For Bioscientists will also earn a place in the libraries of anyone studying medicine, nursing, physiotherapy, pharmacy, and dentistry requiring a refresher or primer on statistical fundamentals.

"Lucidly Integrates Current Activities"

Focusing on both fundamentals and recent advances, Introduction to Machine Learning and Bioinformatics presents an informative and accessible account of the ways in which these two increasingly intertwined areas relate to each other.

"Examines Connections between Machine Learning & Bioinformatics"

The book begins with a brief historical overview of the technological developments in biology. It then describes the main problems in bioinformatics and the fundamental concepts and algorithms of machine learning. After forming this foundation, the authors explore how machine learning techniques apply to bioinformatics problems, such as electron density map interpretation, biclustering, DNA sequence analysis, and tumor classification. They also include exercises at the end of some chapters and offer supplementary materials on their website.

"Explores How Machine Learning Techniques Can Help Solve Bioinformatics Problems"

Shedding light on aspects of both machine learning and bioinformatics, this text shows how the innovative tools and techniques of machine learning help extract knowledge from the deluge of information produced by today's biological experiments.

This book provides a comprehensive overview of music data analysis, from introductory material to advanced concepts. It covers various applications including transcription and segmentation as well as chord and harmony, instrument and tempo recognition. It also discusses the implementation aspects of music data analysis such as architecture, user interface and hardware. It is ideal for use in university classes with an interest in music data analysis. It also could be used in computer science and statistics as well as musicology.

A Dictionary of Biology is an up-to-date reference work explains several thousand specialized words that allow for empirical approaches to the biological sciences. It includes more than bare definitions, including information about most of the things named so as to convey their significance in biological discussion. M. Abercrombie, C. J. Hickman, and M. L. Johnson in effect interpret this language as it is actually used, emphasizing customary usage rather than etymology.

This comprehensive lexicon includes two thousand entries. Many unfamiliar terms, especially the rarer ones, are defined with the help of other technical terms, perhaps equally unfamiliar. This trick of dictionary-makers could only be avoided by giving a complete account of a large part of biology under each heading. Every biological technical term used in a definition is itself defined elsewhere in the dictionary; though some semi-technical terms, words that can be found in any English dictionary are omitted.

The authors use codes throughout the dictionary to help the reader to interpret the use of a word such as whether it is used in relation to plants and animals only, whether the word is an adjective, and when a term is defined elsewhere and adds information to the current definition. The result is an invaluable guide for the layman, the student, and the scholar alike. It presents clear and authoritative explanations of the terms and will remain useful as a quick and concise source of reference.

Art in Science Museums brings together perspectives from different practitioners to reflect on the status and meaning of art programmes in science centres and museums around the world. Presenting a balanced mix of theoretical perspectives, practitioners' reflections, and case-studies, this volume gives voice to a wide range of professionals, from traditional science centres and museums, and from institutions born with the very aim of merging art and science practices. Considering the role of art in the field of science engagement, the book questions whether the arts might help curators to convey complex messages, foster a more open and personal approach to scientific issues, become tools of inclusion, and allow for the production of totally new cultural products. The book also includes a rich collection of projects from all over the world, synthetically presenting cases that reveal very different approaches to the inclusion of art in science programmes. Art in Science Museums should be of great interest to academics, researchers and postgraduate students working in the fields of museum studies, cultural heritage management, material culture, science communication and contemporary art. It should also be essential reading for museum professionals looking to promote more reflective social science engagement in their institutions.

Against standard approaches to evolution and ethics, this book develops the idea that moral values may find their origin in regularly recurring features in the cooperative environments of species of organisms that are social and intelligent. Across a wide range of species that are social and intelligent, possibilities arise for helping others, responding empathetically to the needs of others, and playing fairly. The book identifies these underlying environmental regularities as biological natural kinds and as natural moral values. As natural kinds, moral values help to provide more complete explanations for the selection of traits that arise in response to them. For example, helping in an aquatic environment is quite different than helping in an arboreal environment, and so we can expect the selection of traits for helping to reflect these underlying environmental differences. With the human ability to name, talk, and reason about important features of our environment, moral values become part of moral discourse and argument, helping to produce coherent systems of moral thought. Combining a naturalistic approach to morality with an equal emphasis on moral argument and truth, this book will be of interest to philosophers and historians of biology, theoretical biologists, comparative psychologists, and moral philosophers.

Provides theoretical insights and justification of the statistical procedures for the analysis of high-dimensional data Presents a general framework of regularization methods Covers feature screening for ultrahigh-dimensional data Describes large-scale covariance estimation

This gripping history shows how the electronic devices we use to access care influence the kind of care we receive. The Doctor Who Wasn't There traces the long arc of enthusiasm for-and skepticism of-electronic media in health and medicine. Over the past century, a series of new technologies promised to democratize access to healthcare. From the humble telephone to the connected smartphone, from FM radio to wireless wearables, from cable television to the "electronic brains" of networked mainframe computers: each new platform has promised a radical reformation of the healthcare landscape. With equal attention to the history of technology, the history of medicine, and the politics and economies of American healthcare, physician and historian Jeremy A. Greene explores the role that electronic media play, for better and for worse, in the past, present, and future of our health. Today's telehealth devices are far more sophisticated than the hook-and-ringer telephones of the 1920s, the radios that broadcasted health data in the 1940s, the closed-circuit televisions that enabled telemedicine in the 1950s, or the online systems that created electronic medical records in the 1960s. But the ethical, economic, and logistical concerns they raise are prefigured in the past, as are the gaps between what was promised and what was delivered. Each of these platforms also produced subtle transformations in health and healthcare that we have learned to forget, displaced by promises of ever newer forms of communication that took their place. Illuminating the social and technical contexts in which electronic medicine has been conceived and put into practice, Greene's history shows the urgent stakes, then and now, for those who would seek in new media the means to build a more equitable future for American healthcare.

In competitive sports where an extra breath or a millisecond quicker neural response can spell the difference between fame and mediocrity, a number of myths have persisted around the impact of what might be considered megadoses of various vitamins and trace elements. We do know that a growing body of research indicates that work capacity, oxygen consumption, and other measures of physical performance are affected by a deficiency or borderline deficiency in specific vitamins or essential trace elements. However, when it comes to providing larger doses, the research is conflicted The second edition of Sports Nutrition: Vitamins and Trace Elements, edited by two of the most respected experts in sports nutrition, provides an updated critical review of these reports. The latest volume of this highly popular work includes a collection of chapters written by top researchers from several academic disciplines. Applying their expertise in specific vitamin or trace element nutrition as it relates to exercise and sports, they weigh in on the full alphabet of vitamins as well as a variety of trace elements, incorporating the most recent research. This edition adds chapters on choline and iodine. It also emphasizes new findings on vitamin and mineral metabolic reactions and provides in-depth discussion on the overuse of vitamins to toxic levels and its effect on physical performance. Sports nutritionists, sports medicine and fitness professionals, researchers, exercise physiologists, students, health practitioners, as well as those lay-persons interested in optimal nutrition will find this book especially timely and highly helpful in sorting myth from truth.

The contributors to this book are authors of international and national standing, leaders in the field and trendsetters. The book covers emerging fields of science and important discoveries relating to tomatoes and related products. This represents a one-stop shopping of material related to tomatoes. This book will be essential reading for plant scientists, nutritionists, dieticians, pharmacologists, health care professionals and research scientists.

Go beyond the nutritional value to discover the lesser known health benefits of certain Asian crops Several foods from the Asian culture that are not well known to other parts of the world have health benefits that stretch beyond mere nutritional value. Asian Crops and Human Dietetics comprehensively reviews the plants and spices in the Asian diet which have made significant beneficial contributions to daily health and nutrition. This text not only provides up-to-date summaries of the more familiar Asian food items, but also those that are less widely known. This extensive examination clearly discusses the latest evidence-based scientific studies that document the health benefits and nutritional information of Asian food items. Asian Crops and Human Dietetics conveniently groups the food crops into the food guide pyramid classification, including grains, vegetables, fruits, fats and oils, beans and nuts, spices, and herbal beverages and subsequents. This book closes the gap in knowledge about important and healthful dietary items not generally recognized in Western culture. Diligently researched and exhaustively referenced, this text provides the information as well as scientific evidence together in reader-friendly form. Lesser-known dietary items examined in Asian Crops and Human Dietetics include: millets, such as finger millet and Kodo millet bitter gourd ivy gourd Bok Choy alliums, such as leeks, scallions, and Chinese chive green leafy vegetables, including chekup manis, vegetable drumstick, Ceylon spinach, and fenugreek legumes, such as the winged bean tubers, including elephant yam and taro breadfruit mangoes litchi tamarind jackfruit flaxseed oil rapeseed oil red gram adzuki bean cowpea mung bean herbs, such as Asafoetida, cardamom,

This volume provides reviews covering the latest advances in particular areas of connective tissue research. This comprehensive work also includes areas of the medical field in which the basic aspects could be applied. It explains that both cells and matrix are altered in disease states because of the strong interactions established between cells and the extracellular matrix. The aim of this book is to close the existing gap between basic scientists and clinical investigators. This reference is an absolute must for all biological chemists, clinical investigators, and pathologists. Students of these professions will find this reading both informative and useful as well.

A compilation of published scientific information, including human, animal, cellular, and theoretical studies, Depleted Uranium: Properties, Uses and Health Consequences provides the most current and comprehensive collection of information on depleted uranium health hazards. The editor and her international panel of contributors are clinical and basic researchers at the forefront of toxicology, carcinogenesis, and human epidemiology. They review key findings on DU biological and health effects and comprehensively describe the research progress made during the last 11 years. The book's coverage ranges from cellular malignant transformation and carcinogenesis to animal toxicity and neurotoxicity, and concludes with human medical surveillance studies, uranium measurement methodologies, risk modeling, and environmental modeling. The chapters provide information on cellular and animal studies, in vivo carcinogenesis, risk modeling, uranium measurement methodologies, medical surveillance programs, and environmental monitoring. Focusing on current, peer-reviewed data, this volume is the only available compilation book on the current understanding of the potential health hazards of depleted uranium exposure.

Although there are numerous books on drug metabolism, Radiotracers in Drug Development is unique in explaining how radiotracers are used to elucidate a drug's absorption, distribution, metabolism, and excretion (ADME). Covering traditional and recent technologies and applications, the book takes a strong industrial approach, discussing the basics of scintillation counting and untangling the various data processing methods often specific to individual manufacturers. The chapters include descriptions of the latest micro-plate counters and the growing applications of accelerator mass spectrometry, positron emission tomography, gamma-scintigraphy, and radioluminography. In addition to describing how the analytical technologies work, the contributors explain how the data are interpreted and used in the drug registration process. A unique reference and training aid essential for every drug metabolism department or drug metabolism research team, the book provides insight into the use and practice of ADME in a way that is both instructive and practical. Moving easily across the boundaries of biology, chemistry, and physics, this is the only comprehensive, interdisciplinary resource covering the how-tos of employing radiotracers in drug development. It provides detailed information on how the science is relevant to the registration process.

This textbook is a comprehensive guide to analysis of carbohy-drates by gas-liquid chromatography and mass spectrometry. In addition to explaining the facets of carbohydrate analysis and their relation to each other, the text also contains in-depth reference in-formation useful to practitioners in the field. Improvements in car-bohydrate analyses methodology during the past six years are also highlighted. This extensively illustrated text provides excellent data for those in carbohydrate, agriculture, and food chemistry.

Despite a century of research and attempts to control one of the deadliest foes of mankind, the malaria situation remains a major public health problem. Obviously biological explanations (the resistance of parasites and mosquitoes against available drugs and insecticides respectively) are often given, but they remain partial and incomplete. Indeed, the deterioration of socio-economic conditions due to the policies imposed on many developing countries by international financial institutions, such as the structural adjustment programmes and the mechanism of debt, plays an important role in the malaria situation and its evolution. In the last decade, molecular biology has been a source of great hope for creating genetically-modified mosquitoes able to resist the malaria parasite. If technical progress permits confidence in the creation of such non-vectors, many questions remain open concerning the putative success of their deployment and the resultant reduction of malaria transmission. Indeed the understanding of the coevolutionary processes underlying malaria/mosquito interactions is crucially lacking despite its enormous importance. Moreover, when discussing transgenic mosquitoes, one critical point is the spread of the allele conferring resistance in mosquito populations ensuring the replacement of a or several populations of vectors able to transmit malaria by (theoretically) unable one(s). However, invading a whole population of mosquitoes with a transgene (composed with an allele conferring malaria-resistance and a driving system) is unlikely to be an easy task, it will at least depend on the population structure and on the quality of the driver. Alongside this, it appears that the spread of refractoriness itself is necessary but not sufficient as interactions between the allele of interest, the parasite and the environment may affect refractoriness and thus limit the expected success in terms of malaria control. Indeed the aim of a release of transgenic mosqui

Is life a purely physical process? What is human nature? Which of our traits is essential to us? In this volume, Daniel McShea and Alex Rosenberg a " a biologist and a philosopher, respectively a " join forces to create a new gateway to the philosophy of biology; making the major issues accessible and relevant to biologists and philosophers alike.

Exploring concepts such as supervenience; the controversies about genocentrism and genetic determinism; and the debate about major transitions central to contemporary thinking about macroevolution; the authors lay out the broad terms in which we should assess the impact of biology on human capacities, social institutions and ethical values.

Crime and Intelligence Analysis: An Integrated Real-Time Approach, 2nd Edition, covers everything crime analysts and tactical analysts need to know to be successful. Providing an overview of the criminal justice system as well as the more fundamental areas of crime analysis, the book enables students and law enforcement personnel to gain a better understanding of criminal behavior, learn the basics of conducting temporal analysis of crime patterns, use spatial analysis to better understand crime, apply research methods to crime analysis, and more successfully evaluate data and information to help predict criminal offending and solve criminal cases. A new chapter provides expert advice about terrorist threats and threat assessment. Criminal justice and police academy students, as well as civilians, sworn officers, and administrators, can build the skills to be credible crime analysts who play a critical role in the daily operations of law enforcement.