Following many reports that were published in the last two decades on correlations of multiphase structures of the surface of materials with their antithrombogenicity or biocompatibility a research project ''Design of Multiphase Biomedical Materials'' was carried out in Japan between 1982 and 1986. The objective of this research project was to elucidate various aspects of biomedical behaviour of multiphase systems at the interface with living bodies at the molecular, cellular and tissue levels. Multiphase materials studied cover polymers having microphase-separated structures, hydrogels, immobilized enzymes (or cells), ceramics and metallic materials.
The research project was carried out by the following subgroups:
-- Multiphase biomedical materials with microdomain structures
-- Multiphase biomedical materials containing liquid components
-- Hybrid-type multiphase biomedical materials with biological components
-- Inorganic and metallic multiphase biomedical materials
-- Methods for analysis and evaluation of multiphase biomedical materials
This book contains the results of the research project in an edited form and aims to provoke a better understanding about various aspects of cell--material interactions in which the multiphase systems play a crucial role.

Research indicates that most neurodegenerative diseases, systemic amyloidoses and many others, arise from the misfolding and aggregation of an underlying protein. This is the first book to discuss significant achievements in protein structure-function relationships in biochemistry, molecular biology and molecular medicine. The authors summarize recent progress in the understanding of the relationships between protein misfolding, aggregation and development of protein deposition disorders.

This book is a comprehensive review of the genera of Hydrocharitaceae, a flowering plant family, found in tropical East Africa. It presents information on their character, occurrence, habitat, phenotypic variations and distribution of each of the species under these genera.

Flora of Tropical East Africa - Ruppiaceae (1989) was prepared at the Royal Botanic Gardens/Kew with the assistance from the East African Herbarium. Ruppiaceae submerged monoecious glabrous aquatic herbs of alkaline or brackish water, sometimes in sea-water.

Flora of Tropical East Africa - Aponogetonac (1989) was prepared at the Royal Botanic Gardens/Kew with the assistance from the East African Herbarium. The aponogetonaceae family are rhizomatous glabrous monoecious or rarely dioecious herbs with tubers, usually growing submerged in fresh water or (after drying up) on wet soil.

This book is a comprehensive review of the genera of Moraceae, a family of flowering plants, found in the tropical region of East Africa. It presents information on their character, occurrence, habitat, phenotypic variations and distribution of each of the species under these genera.

This book uses modern biological knowledge to tackle the question of what distinguishes living organisms from the non-living world. The authors first draw on recent advances in cell and molecular biology to develop an account of the living state that applies to all organisms (and only to organisms). This account is then used to explore questions about evolution, the origin of life, and the possibility of extraterrestrial life. The novel approach taken by this book to issues in biology will interest and be accessible to both the general reader as well as students and specialists in the field.

-- Finishing and publishing a PhD is daunting as, for most students, it will be their first experience working within the academic system. This guide offers a helping hand during and when making decisions about how to move on with their career, specifically in the biological sciences. -- Examples are tailored to biological science, offering a unique reference for PhD students in these disciplines. -- The author has authored more than 200 peer reviewed scientific papers and book chapters, and five books. He has been the Editor-in-Chief of an ISI journal for 9 years, and has graduated more than 20 postgraduate students. His blog on writing and publishing in biological sciences is read by thousands globally. -- Most of the 25,000 universities in the world have postgraduates in biological sciences, and emerging economies, such as India and China, will have special interest in this book as their academic systems still fall outside of the academic mainstream. -- The book has many short, easy to read, chapters which are interconnected to provide a comprehensive treatment of each subject, and it explore the 'hot' topics in academic publishing, from Open Access to new blockchain models, as well as academic bullying.

This detailed volume explores the most recent methodologies and applications of stable isotope labeling by amino acids in cell culture (SILAC). With the development of new technologies in the field of mass spectrometry and bioinformatics, SILAC-based methods have become the first tool of choice in quantitative proteomics either on its own or in combination with other more recently developed approaches, which is elucidated in the chapters of this book. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, SILAC: Methods and Protocols serves as an ideal guide for researchers working in the area of functional proteomics and other aspects of protein science.

This volume covers various aspects of affinity chromatography along with examples of its applications. Chapters guide readers through methodologies to purify a diverse array of molecular targets such as antibodies, extracellular vesicles, recombinant proteins, biomarkers, metabolites, plant organelles, nucleic acids, ligand identification and protocols on building affinity matrix. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Affinity Chromatography: Methods and Protocols aims to be an invaluable resource to anyone employing affinity chromatography-based methodologies.

In order to become a registered dietitian starting in January 2024, candidates will have to obtain a graduate degree from the present requirement of a bachelor's degree. Currently in the United States, there are ~ 3,000 dietitians graduating each year. While some of these candidates will choose other graduate pathways such as Food Science or an MBA, the vast majority will likely obtain a graduate degree of Masters of Science in Nutrition and Dietetics. An anticipated 2,000 dietitians per year will enroll in a graduate degree program that will in turn expect them to take in course in pediatric nutrition. Chapter design in ADIME format (see standard blurb) will prepare individuals on how to document a pediatric assessment. This book is written by practicing experts in the field and will represent presence throughout the United States. While this book is written to fulfil needs of the dietetic student population, it serves as a resource for the practicing pediatric dietitian.

The human specificity can be described by verticality/bipedalism, technique use, articulated language, high cognitive capacities, complex society at three levels: body, mind, social. In this book, is proposed an evolutionary process that make better understand how such humanity could have emerged in the long time (more than 6 million years). The process is based on a very early necessity to use technic for surviving correlated with neoteny which impulsed a darwinian evolutionary process, with four distinguished punctuation described as neotenizations.

Why is life the way it is? Bacteria evolved into complex life just once in four billion years of life on earth-and all complex life shares many strange properties, from sex to ageing and death. If life evolved on other planets, would it be the same or completely different? In The Vital Question, Nick Lane radically reframes evolutionary history, putting forward a cogent solution to conundrums that have troubled scientists for decades. The answer, he argues, lies in energy: how all life on Earth lives off a voltage with the strength of a bolt of lightning. In unravelling these scientific enigmas, making sense of life's quirks, Lane's explanation provides a solution to life's vital questions: why are we as we are, and why are we here at all? This is ground-breaking science in an accessible form, in the tradition of Charles Darwin's The Origin of Species, Richard Dawkins' The Selfish Gene, and Jared Diamond's Guns, Germs and Steel.

In this book, an easily understandable account of modelling methods with artificial neuronal networks for practical applications in ecology and evolution is provided. Special features include examples of applications using both supervised and unsupervised training, comparative analysis of artificial neural networks and conventional statistical methods, and proposals to deal with poor datasets. Extensive references and a large range of topics make this book a useful guide for ecologists, evolutionary ecologists and population geneticists.

This volume focuses on the family Violaceae. They are annual or perennial herbs, shrubs or small trees and contains about 22 genera and some 900 species and confines mainly to the old New world tropics and sub tropics, however the genus Viola is predominantly temperate in distribution.

This book contains contributions from leading researchers in biomechanics, nanomechanics, tribology, contact mechanics, materials science and applications on various experimental techniques including atomic force microscopy (AFM) for studying soft, biomimetic and biological materials and objects. Biologists, physicists, researchers applying methods of contact mechanics and researchers testing materials using indentation techniques along with many other applied scientists will find this book a useful addition to their libraries. Moreover, several reviews in this book are written as introductions to several important and rather sophisticated research areas such as depth-sensing indentation, studying of biological cells by AFM probes, mechanics of adhesive contact and contact between viscoelastic (hereditary elastic) solids. The book containing new theoretical models, results of experimental studies and numerical simulations, along with reviews of above mentioned areas of contact mechanics in application to biological systems, would be beneficial for researchers in many areas of biology, medicine, engineering, mechanics and biomimetics.

The Nature of Biological Systems as Revealed by Thermal Methods is a guide for experiments using thermal methods. The Editor has used his many years of experience to create a unique resource that will enable others with a less mathematical background, to realize the beauty and power of this tool and to gain a better understanding of biological problems.

Biological calorimetry (and of course thermal analysis) is of increasing interest and is not covered thoroughly in other resources. The methods presented are macroscopic, for the rather inhomogeneous material (micromethods are often not possible or not pertinent). This book will help beginners in the field of thermal analysis or calorimetry understand the principles of thermodynamics being applied to biological systems. Biological systems are highly organized and very complex. The water and the different types of weak interactions among the macromolecules make the interpretation of thermal events very difficult. This book includes examples how to handle such problems.

The Nature of Biological Systems as Revealed by Thermal Methods is unique in that it:
-has a broad spectrum, from molecules and biochemistry, tissues, and food, to whole organisms;
-combines practical problems (food processing, quality control, thermal denaturation of proteins, plants and small insects, etc.) with concrete solutions and interpretation;
-provides practical strategies and tools without "dry physics and mathematics";
-initiates the application of thermal methods in new fields (e.g. medicine);
-forces the reader to go into more detail of thermodynamics and thermal techniques;
-simplifies communication between biologists, medical doctors and experts of thermal analysis.

The book is an invaluable resource for anyone interested in thermodynamics, including practising professionals applying thermal methods to biological problems; researchers and graduate students beginning work using thermal methods; and specialists of thermal analysis starting work on biological problems. In addition, this book will be a useful resource for libraries and institutes as the only book covering quantitative thermal analysis of biological systems.

This volume focuses on the family Amaranthaceae. They are annual or perennial herbs or subshrubs, rarely lianes and large and mainly tropical family of some 65 genera and over 1000 species, including many cosmopolitan weeds and a large number of xerophytic plants.

The only textbook that completely covers the OxfordAQA International AS & A Level Biology specification (9610), for first teaching in September 2016. Written by expert authors, the engaging, enquiry-based approach ensures a thorough understanding of complex concepts and provides exam-focused practice to build assessment confidence. Help students develop the scientific, mathematical and practical skills and knowledge needed for assessment success and the step up to university. Ensure students understand the bigger picture and support their progression to further study, with synoptic links and a focus on how scientists and engineers apply their knowledge in real life. The online textbook license can be accessed on a wide range of devices and is valid until 31st December 2026, for use by one student or teacher. Your first login will be sent to you in the mail on a printed access card.

Self-organization constitutes one of the most important theoretical debates in contemporary life sciences. The present book explores the relevance of the concept of self-organization and its impact on such scientific fields as: immunology, neurosciences, ecology and theories of evolution.

Historical aspects of the issue are also broached. Intuitions relative to self-organization can be found in the works of such key western philosophical figures as Aristotle, Leibniz and Kant. Interacting with more recent authors and cybernetics, self-organization represents a notion in keeping with the modern world's discovery of radical complexity.

The themes of teleology and emergence are analyzed by philosophers of sciences with regards to the issues of modelization and scientific explanation.

The implications of self-organization for life sciences are here approached from an interdisciplinary angle, revealing the notion as already rewarding and full of promise for the future.