For Senior-level and graduate courses in Biochemical Engineering, and for programs in Agricultural and Biological Engineering or Bioengineering. This concise yet comprehensive text introduces the essential concepts of bioprocessing--internal structure and functions of different types of microorganisms, major metabolic pathways, enzymes, microbial genetics, kinetics and stoichiometry of growth and product information--to traditional chemical engineers and those in related disciplines. It explores the engineering principles necessary for bioprocess synthesis and design, and illustrates the application of these principles to modern biotechnology for production of pharmaceuticals and biologics, solution of environmental problems, production of commodities, and medical applications.

Bioremediation for Environmental Sustainability: Approaches to Tackle Pollution for Cleaner and Greener Society discusses many recently developed and successfully applied bio/phytoremediation technologies for pollution control and minimization, which are lacking more comprehensive coverage in previous books. This book describes the scope and applications of bio/phytoremediation technologies and especially focuses on the associated eco-environmental concerns, field studies, sustainability issues, and future prospects. The book also examines the feasibility of environmentally friendly and sustainable bio/phytoremediation technologies to remediate contaminated sites, as well as future directions in the field of bioremediation for environmental sustainability.

No matter how far Humanity advanced in its successes the problems of health and death will always exist. However, it is possible to postpone old age and prolong life, and it is performed successfully. In ancient Rome the average age was 15-18 years. Today in Japan it reaches 77-79 years. So what can the science of polymers do in solving this problem? Do high molecular compounds (natural and artificial) possess any reserves for solving this problem? This book discusses the problems of the polymer interaction with biologically active and model media, biodegradation biodetrioration, prognosing the time of reliable exploitation of polymers for medical purposes, polymer application in surgery, etc. Also discussed is the role of kinetics in prognosis of agriculture production quality.

Complex fluids include polymers, colloids, emulsions, forms, gels, liquid crystals, surfacants, and other materials that form flowable microstructures. These substances are important in industries producing products such as plastic packaging, paint, ketchup, and toothpaste, and are of vital use to the petroleum, microelectronics, and pharmaceutical industries. This textbook provides both an introduction to these fascinating and important substances and an up-to-date synopsis of the latest advances in understanding the relationship between their structure and flow properties.

This unique handbook contains the most essential engineering formulas used in the cement manufacturing process. All formulas are presented in both English and metric systems of units. Examples are given to familiarize the reader with the usefulness of these formulas. The book can be used as a text manual for courses in cement technology, and as a reference for solving operating problems. The book is equally valuable for the manager supervisor, chemist, and operator as it is to the cement plant engineer. CONTENTS: Cement Chemistry and Quality Control; Kiln Feed Mix Calculations; Chemical and Physical Properties of Materials; Technical Investigations of Kiln Performance; Heat Balance; Sulfur and Alkali Balance in Rotary Kilns; Chain Systems Designs; Cooler Air Balance Technical Investigation of Grinding Circuits; Ball Charges; Grinding Aid Solutions; Useful Formulas in Stearn Engineering Electrical Engineering; Fan Engineering; Fluid Flow; Physical Chemistry; Heat Transfer and Dust Collection; Fundamental Formulas in Algebra; Trigonometry; Statistics; Finances; Safety and Geometry; Conversion Factors for all Units. These titles may also pair well with this book: F.M. LEA's, THE CHEMISTRY OF CEMENT AND CONCRETE, Third Edition: ISBN 978-0-8206-0212-7; Kurt Peray, The Rotary Cement Kiln 2nd Ed.: ISBN 978-0-8206-0-367-4. Visit us at www.chemical-publishing.com

Principles of Parenteral Solution Validation: A Practical Lifecycle Approach covers all aspects involved in the development and process validation of a parenteral product. By using a lifecycle approach, this book discusses the latest technology, compliance developments, and regulatory considerations and trends, from process design, to divesting. As part of the Expertise in Pharmaceutical Process Technology series edited by Michael Levin, this book incorporates numerous case studies and real-world examples that address timely problems and offer solutions to the daily challenges facing practitioners in this area.

The analysis of well tests constitutes one of the most powerful tools for the effective description of a petroleum reservoir and its subsequent management. This requires that the well test be placed in the proper context of related disciplines, especially geoscience, production and reservoir engineering. Modern methods of automated data processing can conceal mathematical limitations and overlook the need for realistic physical and geologic models. This book emphasizes the plausible physical contexts and mathematical models and limitations, and also the importance of realistic geologic models in analysis.Although the book is clearly targeted at petroleum engineers, the approach taken by the authors will no doubt find favour with practitioners in other areas of fluid flow in porous media, such as hydrology and the flow of pollutants. Scattered throughout the book are worked examples of the use of the methods described in the text. It also contains extensive appendices on permeability, application of Laplace transforms to flow equations valid for single and multi-layered systems, convolution and deconvolution, dimensionless parameters and P-theorems, and physical and thermodynamic properties of gases. This book should appeal to students as well as practitioners in industry; many in the latter group may have benefited before from formal exposure to the underlying theory and its limitations in real reservoir environments.

Dieses Buch setzt Impulse zur systematischen Validierung des Bioprintings und zur Etablierung dieser Technologie auch in nicht-medizinischen Anwendungsgebieten. Das dreidimensionale Drucken mit lebenden Zellen erlaubt die kontrollierte Zellimmobilisierung in 3D-Hydrogelgerusten. In dieser Arbeit wird das Bioprinting erstmalig mit Zellkulturen hoeherer Pflanzen gezeigt. Fur die Pflanzenzellbiotechnologie eroeffnen sich damit Perspektiven beispielsweise hinsichtlich der Erzeugung von Gewebemodellen oder der strukturierten Zellimmobilisierung in industriellen Bioprozessen. Die Stroemungsmodellierung im Druckprozess wird auf Basis von ausfuhrlichen rheologischen Messungen der Bioink und der Analyse der Extrusionsgeschwindigkeit gezeigt. Die Darstellung der Ergebnisse im Nomogramm erlaubt eine systematische Optimierung des Druckprozesses.

A Systems Approach to Managing the Complexities of Process Industries discusses the principles of system engineering, system thinking, complexity thinking and how these apply to the process industry, including benefits and implementation in process safety management systems. The book focuses on the ways system engineering skills, PLM, and IIoT can radically improve effectiveness of implementation of the process safety management system. Covering lifecycle, megaproject system engineering, and project management issues, this book reviews available tools and software and presents the practical web-based approach of Analysis & Dynamic Evaluation of Project Processes (ADEPP) for system engineering of the process manufacturing development and operation phases. Key solutions proposed include adding complexity management steps in the risk assessment framework of ISO 31000 and utilization of Installation Lifecycle Management. This study of this end-to-end process will help users improve operational excellence and navigate the complexities of managing a chemical or processing plant.

General Chemistry for Engineers explores the key areas of chemistry needed for engineers. This book develops material from the basics to more advanced areas in a systematic fashion. As the material is presented, case studies relevant to engineering are included that demonstrate the strong link between chemistry and the various areas of engineering.

Nanotechnology in Cancer Management: Precise Diagnostics toward Personalized Health Care provides a well-focused and comprehensive overview of technologies involved in early stage cancer diagnostics via the detection of various cancer biomarkers, both in-vitro and in-vivo. The book briefly describes the advancement in cancer biomarker research relating to cancer diagnostics, covering fundamental aspects of various techniques, especially transduction methodologies, such as electrochemical, optical, magnetic, etc. In addition, it describes approaches on how to make options cost-effective, scalable for clinical application, and user-friendly. Advancements in technology related to device miniaturization, performance improvement and point-of-care applications round out discussions. Final sections cover future challenges, the prospects of various techniques, and how the introduction of nanotechnology in cancer management in a personalized manner is useful.

Reaction Engineering clearly and concisely covers the concepts and models of reaction engineering and then applies them to real-world reactor design. The book emphasizes that the foundation of reaction engineering requires the use of kinetics and transport knowledge to explain and analyze reactor behaviors. The authors use readily understandable language to cover the subject, leaving readers with a comprehensive guide on how to understand, analyze, and make decisions related to improving chemical reactions and chemical reactor design. Worked examples, and over 20 exercises at the end of each chapter, provide opportunities for readers to practice solving problems related to the content covered in the book.

Piezo Channels, Volume 79, the latest volume in the Current Topics in Membranes series provides the necessary membrane research to assist readers in discovering the current state of a particular field and future directions. New chapters in the updated volume include A Tour de Force: The Discovery, Properties, and Function of Piezo Channels, Piezo1 Channels in Vascular Development and the Sensing of Shear Stress, the Origin of the Force: The Force-From-Lipids Principle Applied to Piezo Channels, Genetic Diseases of PIEZO1 and PIEZO2 Dysfunction, and The Structural Basis for Sensing by the Piezo1 Protein. Users of this series will find an up-to-date presentation of the current knowledge in the field of Piezo Channels.

The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Winner of the 2018 PROSE Award in Clinical Medicine from the Association of American Publishers!

Handbook of Industrial Mixing will explain the difference and uses of a variety of mixers including gear mixers, top entry mixers, side entry mixers, bottom entry mixers, on-line mixers, and submerged mixers The Handbook discusses the trade-offs among various mixers, concentrating on which might be considered for a particular process. Handbook of Industrial Mixing explains industrial mixers in a clear concise manner, and also:
* Contains a CD-ROM with video clips showing different type of mixers in action and a overview of their uses.
* Gives practical insights by the top professional in the field.
* Details applications in key industries.
* Provides the professional with information he did receive in school

Green Sustainable Process for Chemical and Environmental Engineering and Science: Green Solvents for Biocatalysis delivers an in-depth overview of biocatalysis in green solvents for industrial applications, also including outlines of sustainable methodologies in the area of organic chemistry, agriculture, analytical chemistry and engineering and pharmaceutical sciences. The book provides unique content in the area, making it a great source for information for undergraduate, postgraduate students, faculty, R&D professionals, production chemists, environmental engineers and industrial experts.

The study of dielectric properties of biological systems and their components is important not only for fundamental scientific knowledge but also for its applications in medicine, biology, and biotechnology. The associated technique - known as dielectric spectroscopy - has enabled researchers to quickly and accurately acquire time- or frequency-spectra of permittivity and conductivity and permitted the derivation and testing of realistic electrical models for cells and organelles. This text covers the theoretical basis and practical aspects of the study of dielectric properties of biological systems, such as water, electrolyte and polyelectrolytes, solutions of biological macromolecules, cells suspensions and cellular systems. The authors' combined efforts provide a comprehensive and cohesive book that takes advantage of the expertise of multiple scientists involved in cutting-edge research in the specific sub-fields of bio-dielectric spectroscopy while maintaining its self-consistency through numerous discussions. The first six chapters cover theoretical, methodological and experimental aspects of relaxation and dispersion in biological dielectrics at molecular, cellular and cellular aggregate level. Applications are presented in the following chapters which are organized in the order of increased complexity, beginning with pure water, amino acids and proteins, continuing with vesicles and simple cells such as erythrocytes, and then with more complex, organelle-containing cells and cellular aggregates. Due to its broad coverage, the text could be used as a reference book by researchers, and as a textbook for upper-level undergraduate classes and graduate classes in (bio) physics, medical physics, quantitative biology, and engineering.