This book is the first to view the effects of development, aging, and practice on the control of human voluntary movement from a contemporary context. Emphasis is on the links between progress in basic motor control research and applied areas such as motor disorders and motor rehabilitation. Relevant to both professionals in the areas of motor control, movement disorders, and motor rehabilitation, and to students starting their careers in one of these actively developed areas.

This textbook and reference fills a critical gap in literature on the comprehensive environmental impacts of industrial organizations. Nineteen chapters examine individual industrial sectors inherent "potential to pollute." The text goes on to analyze new technologies and practices for transforming environmentally degrading effects of industry, and shows how managers can navigate these changes and move their organizations towards long-term environmental sustainability.

The application of microbiological methods to the extraction of metals from minerals has definitely gained a prominent role and is supported by the several bioleaching and biooxidation processes operating in different sites over the world. In recent years new techniques and new results about proteomic and bioinformatics are bringing a new perspective on the microbial processes.

This book focuses on the basic aspects of the process with special emphasis on recent contributions regarding the chemical and microbial aspects of the bioleaching process and the use of microorganisms in the treatment of complex ores and concentrates.

It has been written by recognized researchers in order to introduce the main subjects of microbial processing to undergraduate and postgraduate students, scientists working in this field as well as interested industrialists.

All important aspects of thermophilic moulds such as systematics, ecology, physiology and biochemistry, production of extracellular and intracellular enzymes, their role in spoilage of stores products and solid and liquid waste management, and general and molecular genetics have been dealt with comprehensively by experts in this book which covers progress in the field over the last 30 years since the seminal book Thermophilic Fungi published by Cooney and Emerson in 1964. The experts have reviewed extensive literature on all aspects of thermophilic moulds in a very comprehensive manner. This book will be useful for graduates as well as post-graduate students of life sciences, mycology, microbiology and biotechnology, and as a reference book for researchers.

Recently, there have been significant developments in robust control of time-delay systems. This volume presents a systematic treatment of robust control for such systems in the frequency domain. The emphasis is on systems with a single input or output delay, although the delay-free part of the plant can be multi-input-multi-output, in which case the delays in different channels should be the same.

The author covers the whole range of H-infinity control of time-delay systems: from controller parameterization implementation; from the Nehari problem to the four-block problem; from theoretical developments to practical issues. The major tools used are similarity transformation, the chain-scattering approach and J-spectral factorization.

Self-contained, "Robust Control of Time-delay Systems" will interest control theorists and mathematicians working with time-delay systems. Its methodical approach will be of value to graduates studying general robust control theory or its applications in time-delay systems.

Site-specific mutagenesis of DNA, developed some thirty years ago, has proven to be one of the most important advances in biology. By allowing the site-specific replacement of any amino acid in a protein with one of the other nineteen amino acids, it ushered in the new era of "Protein Engineering". The field of protein engineering has, however, evolved rapidly since then and the last fifteen years have witnessed remarkable advances through the use of new chemical, biochemical and molecular biological tools towards the synthesis and manipulation of proteins. The chapters included in this book reflect the rapid evolution of protein engineering and its many applications in basic research, biotechnology, material sciences and therapy. This book will provide the reader with an introduction to state-of the-art concepts and methods and will be of use to anyone interested in the study of proteins, in academia as well as in industry.

Biodiesel: A Realistic Fuel Alternative for Diesel Engines describes the production and characterization of biodiesel. The book also presents current experimental research work in the field, including techniques to reduce biodiesel's high viscosity. Researchers in renewable energy, as well as fuel engineers, will discover a myriad of new ideas and promising possibilities.

Biofuel is a renewable energy source produced from natural materials. The benefits of biofuels over traditional petroleum fuels include greater energy security, reduced environmental impact, foreign exchange savings, and socioeconomic issues related to the rural sector. The most common biofuels are produced from classic food crops that require high-quality agricultural land for growth. However, bioethanol can be produced from plentiful, domestic, cellulosic biomass resources such as herbaceous and woody plants, agricultural and forestry residues, and a large portion of municipal and industrial solid waste streams. There is also a growing interest in the use of vegetable oils for making biodiesel. "Biofuels: Securing the Planet's Future Energy Needs" discusses the production of transportation fuels from biomass (such as wood, straw and even household waste) by Fischer-Tropsch synthesis. The book is an important text for students and researchers in energy engineering, as well as professional fuel engineers.

A recently established technique termed pharming uses genetically modified plants and animals for the production of biopharmaceuticals. The present interdisciplinary study comprises an extended overview of the state of the art of pharming, as well as in depth analyses of the environmental risks and other ethical and legal issues of pharming. Public attitudes to pharming are investigated on the basis of an original survey in 15 countries worldwide. The study concludes with specific recommendations addressed towards science, industry and politics.

This concise professional reference provides a fundamental framework for the design and operation of solid-state fermentation bioreactors, enabling researchers currently working at laboratory scale to scale up their processes. The authors survey bioreactor types in common use, and describe in depth how to plan a project, and model heat transfer phenomena. The book includes case studies, and a review of practical issues involved in bioreactor performance.

The next article includes the description of the rich chemistry of phosphinines, including azaphosphinines. The sixth article deals with synthetic approaches to different types of 1- heterophosphacyclanes, including four-, five-, and six-membered P-heterocycles. The next two articles cover the chemistry of phosphorus containing mac- cycles. The phosphorus containing calixarenes have attracted much attention in recent years due to their various functions such as metal cations binding, catalysis, molecular recogination, and bioactivity. Likewise, other phosphorus-containing macrocycles, cryptands, and dendrimers find various uses in analytical chemistry and biochemistry. We hope to include the following articles in the second volume on phosphorous heterocycles: Diazaphospholes Selected phosphorous heterocycles containing a stereogenic phosphorus Heterophenes carrying phosphorus functional groups as key structures The synthesis and chemistry of the phospholane ring system Synthesis and bioactivity of 2,5-dihydro-1,2-oxaphosphole-2-oxide derivatives Recent developments in the chemistry of N-heterocyclic phosphines. I would be failing in my duty if I do not express my sincere thanks to the people at Springer, particularly Ms. Birgit Kollmar-Thoni and Ms. Ingrid Samide, for coordinating the project with great dedication.

Numerous applications for biocides have been found in fields as diverse as ethical pharmaceuticals and cat litter products. The aim of this book is two-fold: to provide a comprehensive guide to the use of biocides across a range of applications; and to aid in the selection of a biocide that is "fit for purpose." It covers a cross-section of traditional measures, novel ideas and innovative developments, as well as addressing the biocides market, the political outlook and future trends of biocide use. With contributions by acknowledged experts in the field, Industrial Biocides is a unique title that will be welcomed by many in industry, including industrial and water chemists, microbiologists, and plant and environment managers.

Kinetic Theory of Granular Gases provides an introduction to the rapidly developing theory of dissipative gas dynamics - a theory which has mainly evolved over the last decade. The book is aimed at readers from the advanced undergraduate level upwards and leads on to the present state of research. Throughout, special emphasis is put on a microscopically consistent description of pairwise particle collisions which leads to an impact-velocity-dependent coefficient of restitution. The description of the many-particle system, based on the Boltzmann equation, starts with the derivation of the velocity distribution function, followed by the investigation of self-diffusion and Brownian motion. Using hydrodynamical methods, transport processes and self-organized structure formation are studied.
An appendix gives a brief introduction to event-driven molecular dynamics. A second appendix describes a novel mathematical technique for derivation of kinetic properties, which allows for the application of computer algebra. The text is self-contained, requiring no mathematical or physical knowledge beyond that of standard physics undergraduate level. The material is adequate for a one-semester course and contains chapter summaries as well as exercises with detailed solutions. The molecular dynamics and computer-algebra programs can be downloaded from a companion web page.

This volume contains an archival record of the NATO Advanced Study Institute on Microfluidics Based Microsystems - Fundamentals and App- cations held in Ce ?me-Izmir, Turkey, August 23-September 4, 2009. ASIs are intended to be high-level teaching activity in scientific and technical areas of current concern. In this volume, the reader may find interesting chapters and various microsystems fundamentals and applications. As the world becomes increasingly concerned with terrorism, early - spot detection of terrorist's weapons, particularly bio-weapons agents such as bacteria and viruses are extremely important. NATO Public Diplomacy division, Science for Peace and Security section support research, Advanced Study Institutes and workshops related to security. Keeping this policy of NATO in mind, we made such a proposal on Microsystems for security. We are very happy that leading experts agreed to come and lecture in this important NATO ASI. We will see many examples that will show us Microfluidics usefulness for rapid diagnostics following a bioterrorism attack. For the applications in national security and anti-terrorism, microfluidic system technology must meet the challenges. To develop microsystems for security and to provide a comprehensive state-of-the-art assessment of the existing research and applications by treating the subject in considerable depth through lectures from eminent professionals in the field, through discussions and panel sessions are very beneficial for young scientists in the field."

Designed for chemical engineers and other technical personnel involved in the design, operation, and maintenance of facilities and equipment where deflagration and detonation flame arresters (DDFAs) may be required, this book fosters effective application and operation of DDFAs through treatment of their principles of operation, selection, installation, and maintenance methods. This reference covers a broad range of issues concerning DDAs, including: An overview of deflagration and detonation prevention and protection practicesAn overview of combustion and flame propagation and how DDAs halt propagationDeflagration and detonation flame arrester technologyInstallation in process systemsRegulations, codes, and standardsIllustrative examples, calculations, and guidelines for DDA selectionAppendices, including a glossary, a flame arrester specification sheet for vendor quotation, and a listing of flame arrester manufacturers.

This book covers the principles of cryopreservation as they relate the preservation of viable cells and cell materials being developed for biopharmaceutical applications. Topics include: the principles of freezing and thawing cells, physiochemical phenomena, process and system design options, method selection considerations, preservation procedures, cryoprotectant additives, freeze-drying human live virus vaccines, and transport system selection criteria. Contributions from well-known experts such as Steven S. Lee, Thomas C. Pringle, William H. Siegel, Richard Wisniewski, and Fangdong Yin make this the single most important study available.

Catalysts are increasingly used by chemists engaged in fine chemical synthesis within both industry and academia. Today, there exists a huge choice of high-tech catalysts, which add enormously to the repertoire of synthetic possibilities. However, catalysts are occasionally capricious, sometimes difficult to use and almost always require both skill and experience in order to achieve optimal results. This series aims to be a practical help for advanced undergraduate, graduate and postgraduate students, as well as experienced chemists in industry and academia working in organic and organometallic synthesis.

The series features:

• Tested and validated procedures.

• Authoritative reviews on classes of catalysts.

• Assessments of all types of catalysts.

• Expertise from the Leverhulme Centre for Innovative Catalysis, Liverpool, UK.

The procedure section contains a wide variety of synthetic protocols, such as epoxidations of unsaturated ketones and esters, asymmetric reductions of carbon-oxygen double bonds, asymmetric hydrogenations of carbon-carbon double bonds and other types of reaction. The featured catalysts include a wide range of different materials such as poly-D-leucine, D-fructose-based dioxiranes, oxaborolidine borane, some important titanium and ruthenium complexes as well as baker's yeast. For each reaction there are one or several detailed protocols on how to prepare and employ the various catalysts.

This book gives a comprehensive account of the principles and practical methods applicable to transient temperature measurements in engineering and science. Transient temperatures are taken to be in the range from about 200K to 6000K and with timescales from tenths of nanoseconds to tens of seconds. Within these limits is a very large field of combustion and gas dynamics and these are the principle areas which are addressed. Several new experimental and theoretical techniques are introduced and various modes of thermal failure are described. The chapters move from undergraduate material to the latest methods and are designed to be of use to the widest possible range of engineers, scientists, and students working in universities or in chemical or mechanical engineering. Many applications are described. This book is intended for engineers and scientists concerned with measurement of transient temperatures (rapidly changing heating conditions). Mechanical and chemical engineers experimental physicists chemists.

Principles of Adsorption and Reaction on Solid Surfaces

As with other books in the field, Principles of Adsorption and Reaction on Solid Surfaces describes what occurs when gases come in contact with various solid surfaces. But, unlike all the others, it also explains why. While the theory of surface reactions is still under active development, the approach Dr. Richard Masel takes in this book is to outline general principles derived from thermodynamics and reaction rate theory that can be applied to reactions on surfaces, and to indicate ways in which these principles may be applied. The book also provides a comprehensive treatment of the latest quantitative surface modeling techniques with numerous examples of their use in the fields of chemical engineering, physical chemistry, and materials science. A valuable working resource and an excellent graduate-level text, Principles of Adsorption and Reaction on Solid Surfaces provides readers with:

• A detailed look at the latest advances in understanding and quantifying reactions on surfaces
• In-depth reviews of all crucial background material
• 40 solved examples illustrating how the methods apply to catalysis, physical vapor deposition, chemical vapor deposition, electrochemistry, and more
• 340 problems and practice exercises
• Sample computer programs
• Universal plots of many key quantities
• Detailed, class-tested derivations to help clarify key results

The recent development of quantitative techniques for modeling surface reactions has led to a number of exciting breakthroughs in our understanding of what happens when gases come in contact with solid surfaces. While many books have appeared describing various experimental modeling techniques and the results obtained through their application, until now, there has been no single-volume reference devoted to the fundamental principles governing the processes observed.

The first book to focus on governing principles rather than experimental techniques or specific results, Principles of Adsorption and Reaction on Solid Surfaces provides students and professionals with a quantitative treatment of the application of principles derived from the fields of thermodynamics and reaction rate theory to the investigation of gas adsorption and reaction on solid surfaces. Writing for a broad-based audience including, among others, chemical engineers, chemists, and materials scientists, Dr. Richard I. Masel deftly balances basic background in areas such as statistical mechanics and kinetics with more advanced applications in specialized areas.

Principles of Adsorption and Reaction on Solid Surfaces was also designed to provide readers an opportunity to quickly familiarize themselves with all of the important quantitative surface modeling techniques now in use. To that end, the author has included all of the key equations involved as well as numerous real-world illustrations and solved examples that help to illustrate how the equations can be applied. He has also provided computer programs along with universal plots that make it easy for readers to apply results to their own problems with little computational effort.

Principles of Adsorption and Reaction on Solid Surfaces is a valuable working resource for chemical engineers, physical chemists, and materials scientists, and an excellent text for graduate students in those disciplines.

This book presents the development of modern molecular models for fluids from the interdisciplinary fundamentals of classical and statistical mechanics, of electrodynamics and of quantum mechanics. The concepts and working equations of the various fields are briefly derived and illustrated in the context of understanding the properties of molecular systems. Special emphasis is devoted to the quantum mechanical basis, since this is used throughout in the calculation of the molecular energy of a system. The book is application oriented. It stresses those elements that are essential for practical model development. The fundamentals are then used to derive models for various types of applications. Finally, equation of state models are presented based on quantum chemically based models for the intermolecular potential energy and perturbation theory. The book is suited for graduate courses in chemical and mechanical engineering, physics and chemistry, but may also, by proper selection, be found useful on the undergraduate level.

A comprehensive understanding of the potential dangers inherent in warehousing chemicals is the first step in managing the associated risks. Written by industry professionals for warehouse operators, designers, and all who are concerned with the safe warehousing of chemicals, this book offers a performance-based approach to such hazards as health effects, environmental pollution, fire, and explosion, and presents practical means to minimize the risk of these hazards to employees, the surrounding population, the environment, property, and business operations. These basic precepts can be used to evaluate the risks in initial or existing designs for warehousing facilities on a manufacturing site, for freestanding offsite buildings, and for strictly chemical or mixed-use storage. Each of the book's ten chapters has a list of references and suggestions for further reading. The numerous topics covered make this book invaluable for warehousing designers and operators.

Thermodynamic Models for Chemical Engineering gives an overview of the main thermodynamic models used by engineers and in engineering researcher processes. These fall into two main families, equations of state and activity coefficient models. The book presents the state-of-the-art of purely predictive models.

Das Buch mit zahlreichen Praxisbeispielen befasst sich mit allen wesentlichen Fragen, die f r die Auslegung von Packungskolonnen bei der Rektifikation, Absorption und Strippung (Desorption) unter Vakuum, im Normal- und Druckbereich bis 100 bar, in der Abluft- und Abwassertechnik von Bedeutung sind.

Es wird ein einheitliches, f r beliebige Einbauten geltendes Modell vorgestellt, mit dem die Flutpunktgeschwindigkeit, der Fl ssigkeitsinhalt und der Druckverlust im gesamten Belastungsbereich f r regellose F llk rper, geordnete F llk rperschichten, f r Rohrkolonnen und f r strukturierte Packungen mit unterschiedlicher Neigung der Str mungskan le vorausberechnet werden kann.

Des Weiteren werden Berechnungsunterlagen f r ca. 200 F llk rper und Packungen zusammengestellt. Die zahlreichen Rechenbeispiele - insbesondere f r strukturierte Packungen - erleichtern die Anwendung der abgeleiteten Beziehungen.