Alginate is a hydrophilic, biocompatible, biodegradable, and relatively economical polymer generally found in marine brown algae. The modification in the alginate molecule after polymerization has shown strong potential in biomedical, pharmaceutical and biotechnology applications such as wound dressing, drug delivery, dental treatment, in cell culture and tissue engineering. Besides this, alginates have industrial applications too in the paper and food industries as plasticizers and additives. The few books that have been published on alginates focus more on their biology. This current book focuses on the exploration of alginates and their modification, characterization, derivatives, composites, hydrogels as well as the new and emerging applications.

In this book, a new approach to the theory and practice of two-phase systems based on a global invariant - entropy, - and other invariants is formulated and experimentally confirmed.

This book provides a framework for the development of sustainable bioprocesses. It includes methods for modeling and assessing both the economic and environmental aspects of biotechnological processes and illustrates their application in a series of case studies covering a broad range of products.

The book: provides, in four chapters, an introduction to bioproducts and bioprocesses and the unit operations involved in manufacturing, as well as bioprocess modeling in combination with economic and environmental assessment methods; cuts across multiple process industries, including pharmaceutical, biochemicals, chemicals and food production; addresses risk and uncertainty analysis which are particularly important in early process and product development; presents a unique set of case examples from various parts of biotechnology that improve the understanding of this technology and provide a starting point for developing a specific model.

The CD-ROM included contains the process models described in the text. All process model examples are implemented into SuperPro Designer a. The models are selected as characteristic examples of major bioprocess applications including bulk bio-chemicals, fine chemicals, enzymes, low and high molecular weight pharmaceuticals. Topics covered are: Citric Acid, Pyruvic Acid, L-Lysine, Riboflavin - Vitamin B2, α-Cyclodextrin, Penicillin V, Recombinant Human Serum Albumin, Recombinant Human Insulin; Monoclonal Antibodies, α-1-Antitrypsin from Transgenic Plant Cell Suspension Cultures and Plasmid DNA production. These examples provide a hands-on-approach, which will be useful to both students and professionals already working in bioprocessindustries.

This book provides an integrating framework for the student in chemical and biochemical engineering and the scientist and engineer engaged in process development working in the biochemical, chemical and process industries, as well as biologists, chemists, environmental managers and business economists.

The authors acknowledge the sponsorship of the Deutsche Bundesstiftung Umwelt, Osnabruck, Germany.

In diesem Buch fassen die Autoren, die teilweise drei Jahrzehnte Ingenieurstudenten unterrichteten, ihr chemisches Fachwissen in verstandlicher Form zusammen. Aus verschiedenen Vorlesungen wurden die fur alle ingenieurwissenschaftlichen Fachrichtungen bedeutenden Themenbereiche neu bearbeitet und so erganzt, dass sie auch ohne begleitende Vorlesung verstanden werden konnen.

Die Themen Werkstoffkunde, Halbleiter, Wasserchemie, Elektrochemie, Umweltschutz und Energie sind u.a. inhaltliche Schwerpunkte. Wichtige Industrieprodukte und -bereiche wie Schwefelsaure, Luftflussigung, Ethylen und Erdol, Kalk, Ammoniak, Natronlauge und Chlor sind als Beispiele chemisch-technischer Prozesse mit einbezogen. Ubungen mit Losungen dienen der Vertiefung des erworbenen Wissens.

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This welcome new edition discusses bioprocess engineering from the perspective of biology students. It includes a great deal of new material and has been extensively revised and expanded. These updates strengthen the book and maintain its position as the book of choice for senior undergraduates and graduates seeking to move from biochemistry/microbiology/molecular biology to bioprocess engineering.

New to this edition: All chapters thoroughly revised for current developments, with over 200 pgs of new material, including significant new content in:

Metabolic Engineering

Sustainable Bioprocessing

Membrane Filtration

Turbulence and Impeller Design

Downstream Processing

Oxygen Transfer Systems

Over 150 new problems and worked examples

More than 100 new illustrations

Technological Advancements in Product Valorization of Tea Waste focuses on recent and advanced topics involved with technologies for valorization of tea waste. The book elaborately explains the fundamental concepts of utilization of such waste in the process of conversion as well as current research accomplishments. It emphasizes technologies involved in the major areas of extraction of several important biomolecules like tea polyphenols, polysaccharides for human bioactivity, metal-based nanomaterial synthesis for environmental removal of aquatic pollutants, generation of various different forms of bioenergy including biogas, biodiesel and bioethanol and advanced applications of tea waste in various emerging sectors. Industries covered include the polymer industry, biorefineries, electrical manufacturing and electrochemistry.

Learn Chemical Reaction Engineering through Reasoning, Not Memorization "Essentials of Chemical Reaction Engineering "is the complete, modern introduction to chemical reaction engineering for today's undergraduate students. Starting from the strengths of his classic "Elements of Chemical Reaction Engineering, Fourth Edition, "in this volume H. Scott Fogler added new material and distilled the essentials for undergraduate students. Fogler's unique way of presenting the material helps students gain a deep, intuitive understanding of the field's essentials through reasoning, using a CRE algorithm, not memorization. He especially focuses on important new energy and safety issues, ranging from solar and biomass applications to the avoidance of runaway reactions. Thoroughly classroom tested, this text reflects feedback from hundreds of students at the University of Michigan and other leading universities. It also provides new resources to help students discover how reactors behave in diverse situations-including many realistic, interactive simulations on DVD-ROM. "New Coverage Includes"

• Greater emphasis on safety: following the recommendations of the
• Chemical Safety Board (CSB), discussion of crucial safety topics, including ammonium nitrate CSTR explosions, case studies of the nitroaniline explosion, and the T2 Laboratories batch reactor runaway
• Solar energy conversions: chemical, thermal, and catalytic water spilling
• Algae production for biomass
• Steady-state nonisothermal reactor design: flow reactors with heat exchange
• Unsteady-state nonisothermal reactor design with case studies of reactor explosions

• Summary notes, Web modules, additional examples, derivations, audio commentary, and self-tests
• Interactive computer games that review and apply important chapter concepts
• Innovative "Living Example Problems" with Polymath code that can be loaded directly from the DVD so students can play with the solution to get an innate feeling of how reactors operate
• A 15-day trial of Polymath(TM) is included, along with a link to the Fogler Polymath site
• A complete, new AspenTech tutorial, and four complete example problems
• Visual Encyclopedia of Equipment, Reactor Lab, and other intuitive tools
• More than 500 PowerPoint slides of lecture notes

CO2-philic Polymers, Nanocomposites and Chemical Solvents: Capture, Conversion and Industrial Products is a multidisciplinary book that provides a compilation of concrete information on various polymers, porous materials hydrogels, membranes, nanoparticles, biochar metal-organic frameworks, bioinspired surfaces, polysaccharides, organic solvents, chemicals, eutectic solvents, amine-based chemical compounds, porphyrins, ionic liquids, ceramics and cutting-edge technologies for CO2 sequestration and conversion. Each chapter covers the latest developments and methods of synthesis and applications in the area. The book discusses, in detail, valuable commercial products from CO2, such as ethanol, methanol, formic acid, and precursors of other fine chemicals. The book covers the scientific, technological and practical concepts concerning the research, development and realization of CO2-philic polymers, nanocomposites and chemical solvents. This makes it a valuable resource for academic researchers and graduate students in chemical engineering, materials science and chemical engineers/engineers working in the industry.

New and Future Developments in Microbial Biotechnology and Bioengineering: Trichoderma for Biotechnological Applications: Current Insights and Future Prospects includes the most recent advances in Trichoderma based research. The book emphasizes the use of modern biotechnological and molecular tools such as the identification of Trichoderma, the development of diagnostic markers, and genome mapping and next generation sequencing based approaches. Chapters discuss a variety of applications and illustrations, including the biology and biodiversity of Trichoderma, biotic and abiotic stresses, plant health, disease management, crop improvement, industrial and commercial products, and more. The book includes various applications, making it useful for biotechnologists, biochemical engineers, biochemists, plant breeders, soil microbiologist, agronomists and researchers interested in sustainable agriculture practices.

Biosurfactants: Research and Development provides a thorough overview of biosurfactant research and development across a range of settings and industries, highlighting the novel use of enzymes, metabolic and genetic engineering in biosurfactant production and showcasing diverse experimental models and approaches. Sections discuss fundamental characteristics of biosurfactants, their physio-chemical properties, and their differences from chemically synthesize surfactants, different research approaches for the study of known biosurfactants, and the genetic manipulation of microorganisms to increase biosurfactant productivity, or to produce molecules with improved characteristics. Throughout the book, methods and approaches are discussed in easy-to-digest formats, with methods discussed, ranging from in silico approaches to classical biocatalysis omics analysis and metabolic engineering.

Principles of Multiple-Liquid Separation Systems: Interaction, Application and Advancement describes the basic principles and advancements of multiple-liquid separation systems in downstream processing. Several important elements are included, such as the fundamental process and mechanisms of the multiple-liquid separation system, key principles of the interaction between different solvents and phase components, applications, and green solvents for the separation system. Furthermore, the book gives insights in commercializing this separation technique to industrial scale and making the process environmentally and economically sustainable. The book also presents constructive critics of this separation technique for both past and the latest findings.

The primary concern of environmental sustainability is to: (i) reduce use of physical and depletable resources; (ii) recycle and use renewable resources; (iii) redesign the production process to eliminate the production of toxic materials and protect the environment. Biochar, as a renewable material, can be produced from various sustainable biomass feedstocks through pyrolysis technologies. Biochar Towards Sustainable Environment highlights the contribution of biochar to environmental sustainability. The book provides a detailed overview of the sustainable biomass wastes feedstocks and different technologies for biochar production, and its sustainable applications in various aspects.

This thesis presents a simple, yet highly effective surface engineering solution that uses non-covalent binding peptides to control the autophagy-inducing activity of nanomaterials and nanodevices. The author presents RE-1, a short synthetic peptide that sequence-specifically binds to lanthanide (LN) oxide and upconversion nanocrystals with high affinity, which was discovered using an innovative phage display approach. RE-1 effectively inhibits the autophagy-inducing activity and toxicity of these nanocrystals by forming a stable coating layer on the surface of the nanoparticles, and by reducing their sedimentation and cell interaction. RE- 1 and its variants provide a versatile tool for tuning cell interactions in order to achieve the desired level of autophagic response and are useful for the various diagnostic and therapeutic applications of LN-based nanomaterials and nanodevices.

Fourier Transform Infrared microspectroscopy (FTIR) was first developed by William Coblentz in 1905 for analytical purposes. It has been established as a powerful analytical method to analyze a wide range of materials. The most convenient way to analyze the molecular structure was to prepare KBr pellets with small amount of chemical species. Currently, the development of the Universal Attenuated Total Reflectance (UATR) allows the use of ZnSe-Diamond crystal to acquire FTIR spectra directly from the sample with no special preparation. These traditional FTIR analyses have been made with devices capable of performing single measurements, thus, providing a single IR spectrum of the sample. Recent major technological development in FTIR instrumentation was development of microscopes and imaging systems. These devices are now capable of imaging larger sample area, providing not only spectroscopic information but also spatial distributional information. In addition, the development of Focal Point Array (FPA) has made FTIR imaging an emerging area of chemical imaging research. The aim of this book is to summarize in a single document the research work that is being performed using UATR and IR imaging in selected emerging applications in plant materials and biological samples. This book provides the readers new knowledge, updates information, emerging applications, and understanding of the potential use of FTIR Microspectroscopy.

"Plant and Process Engineering 360" will be the backbone of any plant, chemical, or process engineer s library. This is a broad area in which engineers need to be familiar with a wide array of techniques, technologies andequipment. Its focus on providing a broad introduction to key systems make the book the first point of reference for engineers who are involved with designing, specifying, maintaining or working with plant, process and control technologies in many sectors, includingmanufacturing, chemical process, and energy.
A single-source of plant and processequipment information for engineers, providinga 360 degree view of the critical equipment engineers encounterEnablesreaders to get up to speed with unfamiliar topics quickly withan overview of important but disparate technologies that are specific to plant engineering Coversthe systems and processes that drive effective and efficient plants and processesDrawn from authoritative Elsevier resources, this book is a first port of call with breadth and depth of content, from leading figures in the field."

Safety of Lithium Batteries describes how best to assure safety during all phases of the life of Lithium ion batteries (production, transport, use, and disposal). About 5 billion Li-ion cells are produced each year, predominantly for use in consumer electronics. This book describes how the high-energy density and outstanding performance of Li-ion batteries will result in a large increase in the production of Li-ion cells for electric drive train vehicle (xEV) and battery energy storage (BES or EES) purposes. The high-energy density of Li battery systems comes with special hazards related to the materials employed in these systems. The manufacturers of cells and batteries have strongly reduced the hazard probability by a number of measures. However, absolute safety of the Li system is not given as multiple incidents in consumer electronics have shown.

The first comprehensive, real-world look at two-phase flow systems-from one of the world's leading authorities on the subject.
From his early works in the area of heat transfer research on boundary layer flows and two-phase flows to his role as one of the lead consultants following the Three Mile Island accident, internationally renowned engineer Salomon Levy has achieved an ideal balance of theory and practice in his engineering career. In Two-Phase Flow in Complex Systems, Dr. Levy's newest book, he draws on this breadth of experience to examine these systems in the real world.
Two-Phase Flow in Complex Systems offers a unique look at two-phase flow phenomena (primarily gas and liquid) in a variety of systems, from water reactors to the global climate system. Focusing on the interaction and simultaneous behavior of all the components in a system, the book's approach departs significantly from conventional texts, which emphasize modeling of separate phenomena. The book begins with the formulation of an integrated program of experiments and analytical tools, and describes experimental aspects-specifically the scaling of test facilities-essential to representing the critical elements of the behavior of complex systems. Subsequent chapters:
* Discuss system computer codes for predicting system behavior during transients and accidents.
* Examine flow pattern maps and flow pattern models.
* Describe typical limiting phenomena known to impact the safety and cost of complex systems (including countercurrent limiting conditions and critical or choking flow).
The book also illustrates how the analysis used in understanding the dynamics of a nuclear power system canbe applied to the entire global climate system, including the phenomenon of global warming.

Drawing together topics from a wide range of disciplines, this text provides a comprehensive insight into the fundamentals of magnetic biosensors and the applications of magnetic nanoparticles in medicine. Internationally renowned researchers showcase topics ranging from the basic physical principles of magnetism to the detection and manipulation, synthesis protocols and natural occurrence of magnetic nanoparticles. Up-to-date examples of their clinical usage and research applications in the biomedical fields of sensing by diverse magnetic detection methods, in imaging by MRI and in therapeutic strategies such as hyperthermia, are also discussed, providing a thorough introduction to this rapidly developing field. Each chapter features questions with answers, highlighted definition boxes, and numerous illustrations which help readers grasp key concepts. Mathematical tools, together with key literature references, provide a strong underpinning for the material, making it ideal for graduate students, lecturers, medical researchers and industrial scientific strategists.

This book presents the fundamentals of the reservoir and interfacial engineering. The book systematically starts with the basics of primary, secondary and tertiary (enhanced) oil recovery and emphasizes on the theory of microbial-enhanced oil recovery (MEOR) and its potential toward recovery of oil in place. Different approaches of MEOR such as in-situ, ex-situ, and integration of chemical- and microbial-enhanced oil recovery (EOR) are discussed in detail. This book highlights the link between the effectiveness of MEOR and the local reservoir conditions, crude oil characteristics, and indigenous microbial community. The latest implementations of MEOR across the globe are highlighted as case studies to outline the potential as well as the scope of MEOR. Given the topics covered, this book will be useful for professionals and researchers working in the areas of petroleum science and engineering, chemical engineering, biotechnology, bioengineering, and other related fields.

Those tasked with the planning and construction of infrastructure and development operations face an increasingly uncertain context in which they must address risks across a number of different fields. These range from the environmental and archaeological to the social, political and financial. As a consequence, the formal and informal practices of stakeholders often incorporate projections of risk and opportunity. Project Risks analyzes this paradigm shift. It reviews the origin and nature of these uncertainties, and the practices implemented by the actors to mitigate or take advantage of them. Paradoxically, these practices generate new risks and power relations that are not compatible with the collaborative planning model. These paradoxes force the rethinking of practices such as project territorialization, risk taking in planning and the responsibility of actors, as well as the societal and political choices that must be made between the realization of projects and the protection of the environment.

Ronja Victoria Scholz assesses the performance of cellulose-based Cottonid for implementation as sustainable construction material. Quasi-static and fatigue tests are performed in varying hygrothermal test conditions using mechanical testing systems in combination with integrable climate chambers. To investigate humidity-driven actuation properties, customized specimen holders are designed. Accompanying microstructural in situ experiments in analytical devices enable a profound understanding of effective material-specific damage and failure mechanisms. The findings are transferred into strength-deformation diagrams as well as Woehler curves, which enable a comparative evaluation of several process-related and environmental influencing factors and can directly be used for dimensioning of Cottonid elements for structural applications. The interpretation of thermoelastic material reponse during loading is used as scientific value for lifetime prediction. Comprehensive investigations on industrial standard materials as well as structurally optimized Cottonid variants provide a scientific basis for categorizing material's structural and functional performance towards common technical plastics and wood.

Smart Solutions for Wastewater: Road-mapping the Transition to Circular Economy, the latest release in the Current Developments in Biotechnology and Bioengineering presents up-to-date information on research and technological developments of resource recovery in wastewater treatment in terms of carbon, nutrients and energy. The book fulfils the gaps and current challenges that hinder the application of resource recovery facilities in wastewater treatment plants, discusses knowledge gaps, provides future research perspectives, and discusses strategies to solve problems from a circular economy perspective. It is an excellent, interdisciplinary and updated overview of technologies in terms of potential yields, pollutants removal, nutrients recovery and energy production.

Pinch analysis and related techniques are the key to design of inherently energy-efficient plants. This book shows engineers how to understand and optimize energy use in their processes, whether large or small. Energy savings go straight to the bottom line as increased profit, as well as reducing emissions.
This is the key guide to process integration for both experienced and newly qualified engineers, as well as academics and students. It begins with an introduction to the main concepts of pinch analysis, the calculation of energy targets for a given process, the pinch temperature and the golden rules of pinch-based design to meet energy targets.
Supported by valuable downloadable software, the book shows how to extract the stream data necessary for a pinch analysis and describes the targeting process in depth. Other essential details include the design of heat exchanger networks, hot and cold utility systems, CHP (combined heat and power), refrigeration and optimization of system operating conditions. Many tips and techniques for practical application are covered, supported by several detailed case studies and other examples covering a wide range of industries, including buildings and other non-process situations.
* The only dedicated pinch analysis and process integration guide, fully revised and expanded supported by free downloadable energy targeting software
* The perfect guide and reference for chemical process, food and biochemical engineers, plant engineers and professionals concerned with energy optimisation, including building designers
* Covers the practical analysis of both new and existing systems, with ful details of industrial applications and case studies

At last, a book that covers safety procedures and standards with information that is rarely available outside of proprietary materials. A comprehensive source for basic and essential operations and procedures in use in any facility, the book offers chemical operators and first line supervisors guidance in applying appropriate practices to prevent accidents, and suggests which practices to avoid.