Under the Auspices of the Alfredo and Amalia Lacroze de Fortabat Foundation

This volume is one in a series of monographs being issued under the general title of "Disorders of Human Communication." Each monograph deals in detail with a particular aspect of vocal communication and its disorders, and is written by internationally distinguished experts. Therefore, the series will provide an authoritative source of up-to-date scientific and clinical informa tion relating to the whole field of normal and abnormal speech communication, and as such will succeed the earlier monumental work "Handbuch der Stimm und Sprachheilkunde" by R. Luchsinger and G. E. Arnold (last issued in 1970). This series will prove invaluable for clinicians, teachers and research workers in phoniatrics and logopaedics, phonetics and linguistics, speech pathology, otolaryngology, neurology and neurosurgery, psychology and psychiatry, paediatrics and audiology. Several of the monographs will also be useful to voice and singing teachers, and to their pupils. G. E. Arnold, Jackson, Miss. F. Winckel, Berlin B. D. Wyke, London Preface This book tries to illustrate the practice as well as the principles involved in applying linguistics to the analysis of language disability. In writing it, I have as sumed an audience of professional speech and hearing clinicians who have had little or no formal training in linguistics. Each Chapter therefore begins with a resu me of the main theoretical and descriptive principles needed in order to carry out a clinical linguistic analysis. The relevance oflanguage acquisition studies is a major theme within this resume."

The management of vascular and tumorous lesions of the parasellar region still remains one of the most demanding tasks in neurosurgery. It is only a short time ago that the major concepts of the anatomy of the so-called cavernous sinus were described in detail. Surgical interventions in this region are very complex, they are time-consuming and require an extensive back ground of experience in surgery of the cranial base. Pioneer anatomical studies of the parasellar region done by Taptas, and the daring direct operative approach introduced by Parkinson pro moted the development of modern neuroradiological intervention proce dures, which were initiated by Serbinenko and further refined by Debrun, Vifiuela and others. The technique of the detachable balloon catheter stimulated surgeons to proceed with the direct operative approach to lesions of the parasellar region. Today, it is hard to imagine a successful man agement of vascular pathologies of this region without a complementary use of the two techniques."

Synaptic Mechanisms in the Auditory System willprovide a basic reference for students, clinicians, and researchers on how synapses in the auditory system function to encode acoustic signals. These mechanisms are the groundwork for all auditory processing, and understanding them requires knowledge of the microphysiology of synapses, cellular biophysics, receptor pharmacology, and an appreciation for what these synapses must do for a living, what unique jobs they carry out."

Exposure to loud noise continues to be the largest cause of hearing loss in the adult population. The problem of NIHL impacts a number of disciplines. US standards for permissible noise exposure were originally published in 1968 and remain largely unchanged today. Indeed, permissible noise exposure for US personnel is significantly greater than that allowed in numerous other countries, including for example, Canada, China, Brazil, Mexico, and the European Union. However, there have been a number of discoveries and advances that have increased our understanding of the mechanisms of NIHL. These advances have the potential to impact how NIHL can be prevented and how our noise standards can be made more appropriate.

This volume is one in a series of monographs being issued under the general title of "Disorders of Human Communication." Each monograph deals in detail with a particular aspect of vocal communication and its disorders, and is written by internationally distinguished experts. Therefore, the series will provide an authoritative source of up-to-date scientific and clinical informa tion relating to the whole field of normal and abnormal speech communication, and as such will succeed the earlier monumental work "Handbuch der Stimm und Sprachheilkunde" by R. Luchsinger and G. E. Arnold (last issued in 1970). This series will prove invaluable for clinicians, teachers and research workers in phoniatrics and logopaedics, phonetics and linguistics, speech pathology, otolaryngology, neurology and neurosurgery, psychology and psychiatry, paediatrics and audiology. Several of the monographs will also be useful to voice and singing teachers, and to their pupils. G. E. Arnold, Jackson, Miss. F. Wincke1, Berlin B. D. Wyke, London Since it was their chatter which prompted the question. this book is dedicated to Sarah and VickY; to Peter who provided some of the answers; to Dorothy in gratitude; and to Him who in the beginning was the Word. Preface These pages are the long-delayed product of questions prompted by the sponta neous chatter of my two daughters when they were little. It was only possible to begin to explore these unformed thoughts through the repeated kindness of medi cal friends who allowed me to record their new-born children."

Until recently, the contribution of immunological knowledge to the under standingand management ofENTdisorders was slight, being largely confined to the appreciation that many rhinitic patients were allergic. Happily, this situation is rapidly changing: the immunological basis of many disorders of the ears, nose and throat is becoming recognized and the mechanisms of the reactions involved are being elucidated. From this, rational therapy should evolve. This book aims to highlight some of the areas in which immunological mechanisms are involved in otorhinolaryngology. It is written by experts in their respective fields of immunology and allergy, otology, rhinology and pathology. It opens with an overview ofthe pathways ofthe immune response and the cells and molecules involved, leading to an appreciation of the normal defence mechanisms of the upper respiratory tract and possible areas offailure. There is then a chapter on HIV infection and how this may present to otorhinolaryngologists. The normal function of the tonsil and the immunological effects oftonsillectomy are then considered. The varying roles of fungi in ENT disorders ranging from commensal through allergen to invasive organisms is assessed by Professor R. J. Hay. Perhaps the most obvious immunological contribution to management thus far lies in the immunocytochemical diagnosis of pathological conditions of the ears, nose and throat and this is covered in a chapter by Professor Leslie Michaels."

I have attempted to prepare this volume in such a way as to provide a source of information on the normal physiology of speech and song as well as on the disorders of those functions. To the extent that I have succeeded it should be of interest to physiologists, physicians, and teachers and students of the VOlce. The book is by no means a text on laryngology, nor is it a treatise on the physiology of breathing mechanics, nor yet is it a manual telling how to teach or learn voice production. If none of these, what is it? It is a discussion of the application of breathing mechanics to phonation of interest to the respir- atory physiologist, of certain aspects of physiology and medicine of interest to the teacher or student of voice, and of the problems of voice production and its maladies of interest to the laryngologist. I have undergone a number of experiences during the past 50 years which I believe have qualified me to undertake this task with some special hope of success. In my youth I studied voice for twelve years with four outstanding teachers and performed publicly as a lieder singer, in oratorio, chorus, and opera. Later I trained for and entered the medical profession in the specialty of otolaryngology. Later still I engaged in research on the physiology of breath ing mechanics and phonation, especially singing."

In this text atlas of neuroimaging the author provides a review of the pathologies and diseases that affect the head, brain, skull base, face, spine, and cord. The case presentation format of this handbook covers the important clinical and neuropathological aspects of the disease process. The book contains 350 selected pathologies, represented in 750 high resolution MR images. It also covers the aspects of neurological disorders and the fundamental aspects of the physics of magnetic resonance, spectroscopy, as well as a review of MR techniques. Given its scope, this book is of interest to radiologists involved in MR interpretation, neuroradiologists seeking an up-to-date review, and all workers in the field of diagnostic and therapeutic neurology.

This book covers the clinical approach to managing head and neck pathology as it presents to the otolaryngology department. Including cervical lymphadenopathy, salivary gland disease, oral, oropharyngeal, laryngeal and hypopharyngeal lesions as well as thyroid and parathyroid diseases. Each chapter presents an evidence-based, practical, and user-friendly approach to assessing, investigating and managing these patients A practical, clinically applicable guide to managing head and neck pathology An evidence-based approach to the clear guidance provided in the book. Colour images and flow charts for quick reference Clear, concise and comprehensive, Head, Neck & Thyroid Surgery: An introduction and practical guide will be useful to trainees and clinicians in otolaryngology, maxillo-facial and plastic surgery.

This is a nearly complete collection of Chapters that provide an up to date overview of all aspects of Head and Neck cancer. It is written by professionals but is not only intended for other professionals, but students, patients, policy makers, etc. There are so many aspects to this group of diseases that even the most seasoned professional will learn something from having read this book.

The cochlear implant is a device that bypasses a nonfunctional inner ear and stimulates the auditory nerve directly. Written by the "father" of the multi-electrode implant, this comprehensive text and reference gives an account of the principles underlying cochlear implants and their clinical application. For the clinician, the book will provide guidance in the treatment of patients; for the engineer and researcher it will provide the background for further research; and for the student, it will provide a through understanding of the subject.

This advanced book of rigid fixation describes the scientific principles and applied techniques primarily for the AO/ASIF hardware system.

The Springer Handbook of Auditory Research presents a series of comp- hensive and synthetic reviews of the fundamental topics in modern au- tory research.The volumes are aimed at all individuals with interests in hearing research including advanced graduate students, post-doctoral researchers, and clinical investigators.The volumes are intended to int- duce new investigators to important aspects of hearing science and to help established investigators to better understand the fundamental theories and data in ?elds of hearing that they may not normally follow closely. Each volume is intended to present a particular topic comprehensively, and each chapter will serve as a synthetic overview and guide to the lit- ature.As such the chapters present neither exhaustive data reviews nor original research that has not yet appeared in peer-reviewed journals.The volumes focus on topics that have developed a solid data and conceptual foundation rather than on those for which a literature is only beginning to develop. New research areas will be covered on a timely basis in the series as they begin to mature.

Liposuction began as a contouring procedure but has evolved into the treatment of obese patients, gynecomastia, ptosis, macromastia, and even patients who have complications from heart disease or diabetes. Other disorders such as axillary sweat hypersecretion, lipomas, and angiomas are also potential disorders that may be treated with liposuction.

Physicians performing liposuction must be adequately trained and experienced in the potential and actual complications before attempting to perform liposuction. Patient safety is the most important aspect of all surgeries, but especially of cosmetic surgery, which is an elective procedure.

New technology helps improve results but experience, care, and skill of the cosmetic surgeon is necessary to obtain optimal results that satisfy the patient.

The contributors to this book have spent time and effort presenting the cosmetic and plastic surgeon as much information as possible on the techniques and uses of liposuction for cosmetic and non-cosmetic surgery purposes.

Loudness is the primary psychological correlate of intensity. When the intensity of a sound increases, loudness increases. However, there exists no simple one-to-one correspondence between loudness and intensity; loudness can be changed by modifying the frequency or the duration of the sound, or by adding background sounds. Loudness also changes with the listener's cognitive state. Loudness provides a basic reference for graduate students, consultants, clinicians, and researchers with a focus on recent discoveries. The book begins with an overview of the conceptual thinking related to the study of loudness, addresses issues related to its measurement, and later discusses the physiological effects of loud sounds, reaction times and electrophysiological measures that correlate with loudness. Loudness in the laboratory, loudness of steady-state sounds and the loudness of time-varying sounds are also covered, as are hearing loss and models.

This volume is one in a series of monographs being issued under the general title of "Disorders of Human Communication." Each monograph deals in detail with a particular aspect of vocal communication and its disorders, and is written by internationally distinguished experts. Therefore, the series will provide an authoritative source of up-to-date scientific and clinical informa tion relating to the whole field of normal and abnormal speech communication, and as such will succeed the earlier monumental work "Handbuch der Stimm und Sprachheilkunde" by R. Luchsinger and G. E. Arnold (last issued in 1970). This series will prove invaluable for clinicians, teachers and research workers in phoniatrics and logopaedics, phonetics and linguistics, speech pathology, otolaryngology, neurology and neurosurgery, psychology and psychiatry, paediatrics and audiology. Several of the monographs will also be useful to voice and singing teachers, and to their pupils. G. E. Arnold, Jackson, Miss. August 1980 F. Wincke1, Berlin B. D. Wyke, London Preface Despite years of interest and research in the hearing process, much of the exact detail of auditory processing remains in the realm of conjecture. We do have some rudimentary understanding of the way the system records changes in frequency and intensity and of the relations between the ear's spectrum analysis and our identification of sound quality. Some of these operations we can duplicate with auditory models of our own, or with laboratory analyzers that can serve as auditory analogs."

Twenty five years ago, Bill Stebbins presented the principles of animal psychophysics in an edited volume (Stebbins, 1970) describing an array of modem, creative methodologies for investigating the range of sensory systems in a variety of vertebrate species. These principles included precise stimulus control, a well defined behavioral response, and a rigorous behavioral procedure appropriate to the organism under study. As a generation of comparative sensory scientists applied these principles, our knowledge of sensory and perceptual function in a wide range of animal species has grown dramatically, especially in the field of hearing. Comparative psychoacoustics, i. e. , the study of the hearing capabilities in animals using behavioral methods, is an area of animal psychophysics that has seen remarkable advances in methodology over the past 25 years. Acoustic stimuli are now routinely generated using digital methods providing the researcher with unprecedented possibilities for stimulus control and experimental design. The strategies and paradigms for data collection and analysis are becoming more refined as well, again due in large part to the widespread use of computers. In this volume, the reader will find a modem array of strategies designed to measure detection and discrimination of both simple and complex acoustic stimuli as well experimental designs to assess how organisms perceive, identify and classify acoustic stimuli. Refinements in modem methodologies now make it possible to compare diverse species tested under similar, if not identical, experimental conditions.

Filling a gap in the anatomical and ENT literature, the authors show the various approaches to the middle ear which allow safe surgical manipulations, such as through the tympanic membrane or the Eustachian tube.

This book, containing the proceedings of the 2000 Kyoto Symposium on Esophageal Cancer, is an important contribution for all types of physicians interested in both squamous and adenocarcinoma of the esophagus. The volume has great legitimacy and relevance. The symposia hosted by Professor Masayuki Imamura brought together the leaders in several disciplines from Japan with other acknowledged authorities from Europe, the United States, Australia, and other parts of Asia. Japan has long been a leader in making advances in understanding the pathology, diagnosis, and treatment of esophageal squamous cell carcinoma, for several decades originally led by Professor Komei Nakayama and his students. It is now clear that Japanese are also beginning to suffer from esophageal adenocarcinoma and Barrett's columnar lined epithelium, thus enabling the Japanese to formulate studies on the pathology, diagnosis, and treatment for the full spectrum of esophageal neoplasms. The authoritativeness of these proceedings is established not only by the long tradi tion of Japanese leadership in the field but by the contributions of the principal leaders from the Nakayama school participating in the honorary faculty and local scientific committee.

The question about the function ofsleep remains one ofthe major challenges scientists are faced with. Wherein lies the fascination with sleep? I am convinced that it is the necessity for sleep. No one has failed to experience the overpowering urge to fall asleep after a disturbed night's sleep or after sleep was curtailed or deprived, especially when our daily activities impose restrictions on motor activity. The demand ofour body and brain to sleep challenges our understanding ofwhy this is the case, and which are the benefits ofa night ofprofound sleep. Also in animals prolongation of waking consistently increases their attempts to fall asleep. It has been stated that sleep is more necessary to animals than even food! The need for sleep and some insight into the consequences of the preceding daily waking activities on subsequent sleep was wonderfully formulated by Shakespeare in Othello: Not poppy nor mandragora, Nor all the drowsy syrups ofthe world, Shall ever medicine thee to that sweet sleep Which thou owed'st yesterday It is interesting that the most powerful single intervention which invariably influences sleep in a positive and predictable manner is the prolongation of waking. The activities which people or animals engage in during the wakefulness episode are secondary in the magnitude oftheir effects on sleep.

MRI is assuming a dominant role in imaging of the larynx. Its superior soft tissue contrast resolution makes it ideal for differentiating invasion of tumors of the larynx from normal or more sharply circumscribed configuration of most of the benign lesions. Over ten years ago CT made a major impact on laryngeal examination because it was the first time that Radiologists were beginning to look at submucosal disease. All of the previous examinations duplicated the infor mation that was available to the clinician via direct and in-direct laryngo scopy. With the advent of rigid and flexible endoscopes, clinical examination became sufficiently precise that there was little need to perform studies such as laryngography which merely showed surface anatomy. The status of deep structures by these techniques was implied based on function. Fortunately laryngography is now behind us together with all of the gagging and contrast reactions which we would all like to forget. CT is still an excellent method of examining the larynx but it is unfortunately limited to the axial plane. With presently available CT techniques motion deteriorates any reformatting in sagittal or coronal projections. The latter two planes are extremely helpful in delineating the vertical extent of submucosal spreads. MRI has proven extremely valuable by producing all three basic projections, plus superior soft tissue contrast. Although motion artifacts still degrade the images in some patients, newer pulsing sequences that permit faster scanning are elimi nating most of these problems."

Throughout the world, head and neck cancer is a major threat to public health and a significant challenge to both clinicians and basic scientists. Despite extensive efforts in primary prevention, screening, early detection, and therapy, long-term survival rates have not improved substantially in the last three decades. This book covers a wide range of exciting new findings in both clinical and basic sciences as they are relevant to head and neck cancer. These findings have recently enhanced our understanding of head and neck carcinogenesis at the genetic and molecular levels, offering the promise of improved preventive and therapeutic strategies. This book will also present information on the important clinical advances that have been made in chemoprevention, organ preservation, and the simultaneous use of chemo therapy and radiotherapy. The first part provides an overview of the etiology and biology of head and neck cancer, including an examination of human papillomaviruses in both benign and malignant lesions. This section also discusses the carcinogenic process at the genetic and molecular levels, as well as aberrant squamous differentiation; increased understanding of these areas has great potential to translate into new strategies for cancer prevention. The second part describes recent advances in developing a risk model for head and neck cancer, as well as the application of genetic susceptibility data in chemoprevention. This section also includes overviews of the status of chemoprevention trials and of the process of invasion and metastasis in head and neck cancer."

The increasing prevalence of musical stimulation in our everyday environment makes studies of musical listening, comprehension and memory important. Music has simply become a pervasive aspect of the experienced environment for most of us; along with enhanced levels of machine sounds, musical sound sources are contributing to a virtual transformation of contemporary soundscapes occurring in many industrial countries. In spite of such trends, arguably the mainstream research in psychology and related fields has been slow to devote concentrated attention to this phenomenon and what it might mean. As a result, with respect to more established fields of research (e.g., visual perception, speech perception, attention and memory etc.), less is known about how people perceive and respond to complex, non-random, acoustic signals found in musical events. Although these topics reside in the domain of music research, this field is a relatively new one, with a history that dates back only about 25 years. Nevertheless, it is now a vibrant and rapidly growing field that draws from multiple disciplines (psychology, psychoacoustics, computer science, music theory, and so forth) to seek answers to questions about how we listen to musical events in our world. It tackles questions about pitch perception in complex patterns, about the role of tonal schemes as well as effects of metrical and rhythmic schemes on musical listening behaviors. It also examines abilities of children and adults to perceive and comprehend dynamic sound patterns. Emotional responses to music are also studied; and overarching all of this are exciting new neuroscience findings concerned with neural responses to musical events.

Music Perception introduces its audience to these and related basic issues concerned with listening to music. It also illustrates how knowledge about music perception may ultimately lead to a broader understanding of conventional concepts regarding perception, attention and memory.

Originally published in 2007 and now available for the first time in paperback format, Head and Neck Manifestations of Systemic Disease presents critical information on a multitude of maladies that have manifestations in the head and neck. The book relates commonly encountered head and neck symptoms and signs to an array of diseases and disorders that should be considered in the differential diagnosis. Offering a hands-on approach, this volume addresses specific disease classifications and commonly encountered signs and symptoms in the head and neck region. It offers a clinical approach to disease diagnosis by analyzing the possible causes of a patient's symptoms. The contributors present evidence-based therapeutic options for a variety of conditions, from infections and rheumatologic conditions to hematologic and neoplastic disease. Organized by disease type for easy reference, the book offers a variety of lucid color photographs, providing a unique reference for clinicians who manage diseases with symptoms in this region.