Until recently, the contribution of immunological knowledge to the under standingand management ofENTdisorders was slight, being largely confined to the appreciation that many rhinitic patients were allergic. Happily, this situation is rapidly changing: the immunological basis of many disorders of the ears, nose and throat is becoming recognized and the mechanisms of the reactions involved are being elucidated. From this, rational therapy should evolve. This book aims to highlight some of the areas in which immunological mechanisms are involved in otorhinolaryngology. It is written by experts in their respective fields of immunology and allergy, otology, rhinology and pathology. It opens with an overview ofthe pathways ofthe immune response and the cells and molecules involved, leading to an appreciation of the normal defence mechanisms of the upper respiratory tract and possible areas offailure. There is then a chapter on HIV infection and how this may present to otorhinolaryngologists. The normal function of the tonsil and the immunological effects oftonsillectomy are then considered. The varying roles of fungi in ENT disorders ranging from commensal through allergen to invasive organisms is assessed by Professor R. J. Hay. Perhaps the most obvious immunological contribution to management thus far lies in the immunocytochemical diagnosis of pathological conditions of the ears, nose and throat and this is covered in a chapter by Professor Leslie Michaels."

The auditory system is a complex neural system composed of many types of neurons connected into networks. One feature that sets the auditory system apart from other sensory systems, such as somatosensory or visual systems, is the many stages of neural processing that occur between the ear in the periphery and the cerebral cortex. Each stage is composed of specialized types of neurons connected in specific microcircuits that perform computations on the information about sound. To understand this processing, all the tools of neuroscience must be employed. The proposed text integrates cell biology, synaptic physiology, and electrophysiology to fully develop the topic, presenting an overview of the functional anatomy of the central auditory system. It is organized based on the neuronal connectivity of the central auditory system, which emphasizes the neurons, their synaptic organization, and their formation of functional pathways and microcircuits. The goal of the book is to stimulate research into the cell biology of the central auditory system and the characteristics of the specific neurons and connections that are necessary for normal hearing. Future research on the development of the central auditory including that employing stem cells will require such information in order to engineer appropriate therapeutic approaches.

For more than 30 years, the highly regarded Secrets Series (R) has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. ENT Secrets, 5th Edition, offers practical, up-to-date coverage of the full range of essential topics in this dynamic field. This highly regarded resource features the Secrets' popular question-and-answer format that also includes lists, tables, pearls, memory aids, and an easy-to-read style - making inquiry, reference, and review quick, easy, and enjoyable. The proven Secrets Series (R) format gives you the most return for your time - succinct, easy to read, engaging, and highly effective. Coverage includes the full range of topics in otolaryngology, from basic science to obstructive sleep apnea to the aging neck and face. New chapters cover pharyngitis and laryngitis, evaluation of hearing, hearing loss and ototoxicity, and cochlear implants. Fully revised and updated, including protocols and guidelines that are continuously evolving and that increasingly dictate best practices. Top 100 Secrets and Key Points boxes provide a fast overview of the secrets you must know for success in practice and on exams. Bulleted lists, mnemonics, practical tips from global leaders in the field - all providing a concise overview of important board-relevant content. Portable size makes it easy to carry with you for quick reference or review anywhere, anytime. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This book provides the description of the granulomatous diseases of otorhinolaryngology, head and neck with their characteristic features, investigations and management. It includes wide variety of infective, idiopathic, neoplastic, hereditary, reactive and various other types of chronic granulomatous reaction in the ear, nose, throat and head neck region. Further, the description is supported with various illustrations including clinical photographs, radiological pictures of CT scan, MRI scan etc. Histopathological and microbiological images which show characteristics and differentiating features are also included to aid in the diagnosis of the diseases. Histopathological colored images with high magnification and immunohistochemistry images are provided for better illustrations. This book also elaborates the important medical and surgical management of the granulomatous diseases. Every chapter ends with the 'Essential features' of that particular granulomatous disease, and this will certainly help the post-grad students and clinicians to differentiate the diseases, early diagnosis and management of the patients with chronic granulomatous diseases.

The vestibular labyrinth consists of ? ve compartments: the lateral, anterior, and posterior semicircular canals, the utricule, and the saccule. At the beginning of the twentieth century, Robert Barany proposed the caloric test as a clinical test of the lateral semicircular canal. This test enabled clinicians to assess the individual lateral semicircular canal function easily by using the simple method of irrigating the external ear canal with cold or warm water and observing the induced nyst- mus. We believe that the caloric test was a breakthrough in the ? eld of vestibular research. However, as far as the other compartments were concerned, there was no simple clinical test equal to the caloric test for the lateral semicircular canal function. At the end of the twentieth century, the vestibular evoked myogenic potential (VEMP) test was proposed as a new method for assessing the individual saccule function. This test has some unique attributes. First, it uses sound stimulation, even though it is a test of the vestibular system. This appears to be a contradiction n- rophysiologically. As a result, in its early stages there were controversies conce- ing the origin of the responses. However, such controversies have been overcome by basic neurophysiological studies and clinical studies. Above all, sound sensit- ity of the saccular afferents shown in cats and guinea pigs with single-unit recording methods became the main supporting evidence. Nowadays, VEMP is one of the routine clinical tests for balance disorder."

This is the fifth book in an international, multi-contributed series aimed at providing practical, clinical guidance on how to deal with difficult symptoms related to specific cancer sites. In this volume the Editors bring together first-rate palliative care with oncological treatment for patients with head and neck cancer. Head and neck cancer is one of the most frightening and distressing cancers for patients and their families as it affects appearance, the ability to speak, and the ability to eat. Pain which is difficult to treat, infection, and disfiguring surgery with wounds that often do not heal, are common accompaniments of advanced disease. In addition, psychological distress, loneliness, and isolation are often experienced by patients. Head and neck cancer is not that common but, when it does occur, it very often needs specialist help from palliative care and hospice clinicians. There is little written on this subject and this book provides a comprehensive, practical guide that draws together all the information in an easily accessible format. It is an essential reference for on the ward, or before going to a home visit. The Palliative Care Consultations series is primarily aimed at those individuals working in an acute hospital cancer centre and/or tertiary referral centre. Books are designed to give the busy clinician advice on clinical problems, both those rarely encountered and those that are very common, but difficult. The volumes are site specific and each volume encompasses a review of the current oncological or haemato-oncological management of advanced disease with symptom control advice. These volumes give clinicians excellent advice on symptom control in the context of palliative care. The books are also of use and interest to other professions working in acute hospitals.

In this issue of Sleep Medicine Clinics, guest editor Dr. Matthew R. Ebben brings his considerable expertise to the topic of PAP Therapy for the Treatment of OSA. Positive airway pressure (PAP) is the treatment of choice for patients with moderate-to-severe obstructive sleep apnea (OSA). Randomized controlled trials have demonstrated that PAP can effectively reduce the apnea-hypopnea index and improve subjective and objective sleepiness. In this issue, top experts provide an up-to-date review of PAP therapy for the treatment of OSA. Contains 14 practice-oriented topics including racial differences in PAP adherence in the treatment of sleep apnea; cost/benefit analysis of CPAP vs other treatments for OSA; best predictors of PAP compliance; the effect of insomnia on OSA treatment; cognitive complaints and comorbidities that present in patients with OSA; and more. Provides in-depth clinical reviews on PAP therapy for the treatment of OSA, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This is the first Q&A-based revision book specifically aimed at candidates sitting the viva component of the FRCS(Plast) examination. It provides a selection of common clinical scenarios presented in a realistic way and presents a guide to answering the FRCS (Plast) questions, as well as advice on how to approach the revision process itself. Crucially, this will help to prepare candidates to organise their thoughts, demonstrate higher order thinking and present a robust answer in the face of grey areas and controversies. The text covers all topics from the syllabus including Trauma, Burns, Facial and Soft Tissue Injuries, Acute Head and Neck Tumours, Cleft and Craniofacial, Congenital anomalies, Facial Palsy, Vascular anomalies, Trunk & Perineal, Skin Cancer, Basic Sciences, Aesthetic, Ethics & Medico-legal, and Consent. Candidates using this book will be able to realistically recreate the exam scenario either in private or in a group setting. This book is equally useful for candidates sitting plastic surgery post graduate exams with equivalent syllabuses to that of the FRCS(Plast) such as the EBOPRAS exam, as well as others. In addition, it also makes an excellent companion for trainees throughout the course of their six-year training rotation, allowing more junior plastic surgery trainees the opportunity to become acquainted with the format and content of the FRCS (Plast) exam. Lastly it may be helpful to consultants who are interested in coaching their trainees in topics other than their subspeciality.

Revised and expanded for the third edition, this book is both a guide for your first ENT job and a tried and tested revision guide covering all aspects of the MRCS (ENT) OSCE. Written by a team of ENT specialists, the accessible text follows a step-by-step approach with each OSCE station based on the style of past questions. Recent changes in the structure of the examination, together with the nature of the examination in both COVID and post-COVID contexts are included. With over 120 colour images, the guide remains unrivalled as a tool with which to prepare for ENT exams. It is essential reading for candidates of the MRCS (ENT) OSCE and will also aid trainees in preparation for specialty registrar national selection interviews. It is highly recommended for GPs wishing to refresh their knowledge of how to assess common ENT problems and will also be an ideal reference for any junior doctor learning to take histories and examinations in their first ENT post. Finally, it is an invaluable resource for medical students undertaking their ENT attachment and in preparation for final examinations.

This clear and concise text covers all the assessable aspects of the ENT curriculum for the FRCS. Although technique and presentation of knowledge will no doubt be attained through viva practice, the comprehensive content ensures that all candidates have the relevant knowledge not only to succeed, but also to excel in their viva examination. Covering both the theoretical and clinical aspects of the examination, as well as other equally critical aspects, including communication skills, clinical examination and miscellaneous sections, this handbook is a high yield revision aid for all surgical trainees in the early stages of their Otolaryngology careers, and simultaneously acts as an emergency information source for those cross-covering the specialty. ENT and Otorhinolaryngology surgical trainees and Residents will find the scope of this guide highly relevant to obtain FRCS accreditation or equivalent.

This book reviews current knowledge of the etiopathogenesis, pathophysiology, and molecular biology of tympanic membrane retraction pockets and provides clear guidance on clinical assessment and treatment. A new diagnostic approach based on clinicoradiologic correlations is presented, and the ability of computer tomography to offer objective criteria for improved differentiation between stable and unstable or unsafe retraction pockets is explained. Surgical options are discussed, and on the basis of their own clinical and surgical experiences the authors propose a novel procedure, masto-atticotomy with anterior epitympanotomy (AER surgery), which addresses the causative factors underlying a retraction pocket. This surgery aims to restore adequate aeration routes for the middle ear compartments situated above the tympanic diaphragm; it results in better control of the pathology and in most cases prevents its recurrence. The book will assist otologists and surgeons in ensuring that retraction pockets are effectively diagnosed and treated, avoiding progression to cholesteatoma.

This book provides a state-of-the-art overview of dysphagia. The text reviews current evidence behind the diagnosis, evaluation, and management of esophageal disorders that cause dysphagia, including GERD, eosinophilic esophagitis, achalasia, and spastic motor disorders. The book also focuses on the different variants of dysphagia, from oropharyngeal dysphagia to functional dysphagia, highlights advances in testing for dysphagia, and features evidence-based algorithms. Written by experts in the field, Evaluation and Management of Dysphagia: An Evidence-Based Approach is a valuable resource for gastroenterologists, otolaryngologists, and other clinicians and practitioners who treat patients afflicted with dysphagia.

Hearing Loss: Causes, Prevention, and Treatment covers hearing loss, causes and prevention, treatments, and future directions in the field, also looking at the cognitive problems that can develop. To avoid the "silent epidemic" of hearing loss, it is necessary to promote early screening, use hearing protection, and change public attitudes toward noise. Successful treatments of hearing loss deal with restoring hearing sensitivity via hearing aids, including cochlear, brainstem, or midbrain implants. Both the technical aspects and effects on the quality of life of these devices are discussed. The integration of all aspects of hearing, hearing loss, prevention, and treatment make this a perfect one-volume course in audiology at the graduate student level. However, it is also a great reference for established audiologists, ear surgeons, neurologists, and pediatric and geriatric professionals.

The new edition of this book provides an up-to-date and comprehensive overview of whiplash-associated disorders, focusing in particular on a functional approach to clinical and instrumental diagnosis and rehabilitative treatment. It fully reflects the changes in our understanding of whiplash injuries since the first edition, and in particular the increased awareness that whiplash is a whole-body trauma in which forces act progressively from the lumbar region to the brain, through the cervical spine. Detailed attention is paid to the functional connections between the sense organs of the inner ear, the sympathetic system, and the spine with a view to optimizing diagnosis and treatment. It is explained how various treatment options can be employed to best effect in patients with different symptoms, following, but updating, the well-known Quebec Task Force guidelines. Underestimated aspects such as positional vertigo, somatic tinnitus, temporomandibular disorders, and back pain are also considered. This book will be an invaluable tool in everyday clinical practice for all who are involved in the diagnosis and treatment of whiplash injury.

"Principles of Deglutition" is the first in class comprehensive multidisciplinary textbook to encompass the entire field of normal and disordered deglutition. It is designed as the definitive text for all those who desire to further their knowledge of the dynamic and expanding field of deglutology. The text is created to serve as a treasured reference for clinicians, educators and trainees from such diverse backgrounds as gastroenterology, speech language pathology, otolaryngology, rehabilitation medicine, radiology and others.

"Principles of Deglutition" brings together the state-of-knowledge from 12 disciplines involved in dysphagia through contributions of over one hundred thought leaders and master clinicians for the benefit of patients and providers alike. It concisely organizes the wealth of knowledge that exists in each of the contributing disciplines into one comprehensive information platform.

"Principles of Deglutition" provides a one-stop destination for members of all specialties to obtain state-of-the-art and critically reviewed information regarding deglutition physiology, pathophysiology, diagnosis and management. It delivers a comprehensive and in depth review of deglutition related cerebral cortical, brainstem, peripheral nerves, and neuromuscular mechanisms, advanced diagnostic modalities and standard of care and cutting edge medical, rehabilitative and surgical treatments. It is an essential reference for all deglutologists.

Prescription opioid abuse has become a major issue around the world, especially within the United States and Canada. Surgeons' high rate of opioid prescriptions places them in a critical position of working with patients to manage their pain. Opioid Use, Overuse, and Abuse in Otolaryngology, edited by Dr. Ryan J. Li of Oregon Health and Sciences University, takes a comprehensive, practical look at the national opioid epidemic and provides specific otolaryngology-specific data on chronic opioid usage. Discusses perioperative pain management in otolaryngology from an anesthesiology perspective, perioperative pain management in pediatric otolaryngology, rhinology and anterior skull base surgery, facial plastic and reconstructive surgery, neurotology, head and neck cancers, and more. Offers nonopioid analgesic options for otolaryngology-head and neck surgery patients and discusses a structured approach to perioperative pain management. Presents the knowledge and expertise of leading experts who have assembled the most up-to-date recommendations for opioid use, overuse, and abuse, including international pain management approaches. Covers the history of perioperative pain management in otolaryngology-head and neck surgery.

This issue of Otolaryngologic Clinics, guest edited by Drs. Maja Svrakic and Meredith E. Adams is devoted to The Dizzy Patient. This issue is one of six selected each year by our series consulting editor, Dr. Sujana S. Chandrasekhar. With its broad differential diagnosis and significant impact on quality of life, dizziness is a common symptom that presents substantial diagnostic and therapeutic challenges. This issue focuses on the clinical evaluation and management of the range of dizziness symptomatology and syndromes. Articles in this issue include: Overview of dizziness in practice; Interviewing and counseling the dizzy patient with focus on quality of life; The efficient dizziness history and exam; Efficient use of audiovestibular testing; Neuroimaging of dizziness and vertigo; Positional vertigo; Acute vestibular syndrome and ER presentations of dizziness; Chronic central vestibulopathies for the otolaryngologist; Vestibular migraine and its comorbidities; Progressive and degenerative peripheral vestibular disorders; The dizzy child; Neuropsychology of dizziness and related disorders; Non-vestibular dizziness; Vestibular therapy and fall risk assessment; Current and emerging medical therapies for dizziness; Allergy, immunotherapy and alternative treatments for dizziness; and New frontiers in managing the dizzy patient. Provides in-depth, clinical reviews on dizzy patients, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

Perspectives on Auditory Research celebrates the last two decades of the Springer Handbook in Auditory Research. Contributions from the leading experts in the field examine the progress made in auditory research over the past twenty years, as well as the major questions for the future.

The now classic "Pocket Pasha"-Otolaryngology-Head and Neck Surgery: Clinical Reference Guide-returns for its sixth edition. This universally standard guidebook concisely reviews all aspects of otolaryngology including rhinology, laryngology, otology, plastic surgery, sleep medicine, and more. All chapters focus on the key basic science and clinical information to quickly digest the essentials. This "high-yield" book retains a "by residents, for residents" feel while also including expert content useful not only for students and residents but also allied health professionals, primary care providers, and other health providers. The concise, outline format is useful for rapid reading during urgent clinical situations as well as a last-minute refresher before rounds. The guide has proven essential for board review and maintenance of certification exams. The sixth edition of this bestselling reference features numerous improvements, including: *Line by line refresh and update of all relevant material *Additional images, figures, and charts *Expanded focus on evidence-based practice *Addition of latest treatment modalities (including investigative medications) *A host of new contributing authors and subspecialized leading authorities *A new appendix for common otolaryngology-head and surgery consults *A PluralPlus companion website containing a digital bank of board-like study questions with explanation

With its step-by-step approach and brilliant full-color design, Otologic Surgery, 5th Edition, provides the authoritative guidance you need to hone your surgical skills and ensure optimal outcomes for your patients. Renowned leaders in the field, led by Drs. Derald Brackmann, Clough Shelton, Moises Arriaga, and Richard K. Gurgel , cover surgical approaches to the ear and skull base, techniques, alternate approaches, and controversial issues. Hundreds of crisp line drawings, high-quality photographs, and more than 60 procedural videos provide detailed visual guidance. Covers key procedures such as tympanoplasty and mastoidectomy, stapedectomy, and skull base surgery-everything from eardrum repair to complex skull base tumor removal. Provides step-by-step coverage of each procedure, including patient evaluation, patient selection, and patient counseling. Offers fully updated content throughout, with new content on endoscopic ear procedures, implantable hearing devices, and much more. Includes pediatric sections and revision surgery sections in each relevant chapter. Features an expanded video library covering facial reanimation, endoscopic techniques, infratemporal fossa approach, laser stapedotomy, exostosis repair, and more. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This issue of Otolaryngologic Clinics, Guest Edited by Drs. Manuela Fina, Justin S. Golub, and Daniel Lee, is devoted to Endoscopic Ear Surgery. This issue is one of six selected each year by our series Consulting Editor, Sujana S. Chandrasekhar. Articles in this important issue include: History of Endoscopic Ear Surgery; Endoscopes and Exoscopes for Otology and Neurotology; Redefining middle ear anatomy and physiology; Getting started with Endoscopic Ear Surgery; Otoendoscopy in the Office and Operating Room; Teaching Tools for Endoscopic Ear Surgery; Endoscopic Myringoplasty and Tympanoplasty; Novel Radiologic Approaches for Cholesteatoma Detection; Endoscopic Ear Surgery for Congenital Cholesteatoma; Endoscopic Management of Pediatric Chronic Ear Disease; Endoscopic Management of Acquired Cholesteatoma; Endoscopic Stapes Surgery; Endoscopic-assisted Lateral Skull Base Surgery; New Navigation Approaches for Endoscopic Lateral Skull Base Surgery; Endoscopic-assisted Drug Delivery for Inner Ear Regeneration; Pearls and pitfall in Endoscopic Ear Surgery; Future of Endoscopic Ear Surgery; and The Role for Microsurgery of the Ear.

The completely revised and updated edition --with essential information on improved treatments
Earlier editions of this text have established it as an excellent primer for radiotherapy of head and neck cancers. Now this new volume brings this material fully up to date with recent developments concerning treatment techniques, use of modalities, and the management of early and advanced tumors. With fresh data published here for the first time, this superb resource has been extensively reworked to include:
* A broad range of strategies for managing carcinomas of the oral cavity, horopharynx, hypopharynx, larynx, nasopharynx, paranasal sinuses, nasal cavity, salivary glands, and eye.
* Greatly expanded material on applied anatomy, treatment methods, and technical pointers.
* Detailed site-specific treatment coverage--pathology, staging, selection of modalities, radiation techniques, current treatment data, and more.
* An in-depth case study analysis, comparing conventional radiation therapy to altered fractionation radiation therapy.
* A separate chapter on dental care before, during, and after radiation therapy.
* New illustrations throughout, plus over 100 photographs
This text provides invaluable guidance on the management of head and neck neoplasms to radiation oncologists, head and neck surgeons, oral surgeons, medical oncologists, medical students, and residents.

This book, which brings together some 30 contributors from the leading experts in this field, is based on papers presented at the Second International Conference on Intracranial and Inner Ear Fluids: Basic Aspects and Clinical Applications, held in Bath in 1997. The aim of the meeting was to bring together neuroscientists, neurosurgeons, otolaryngologists, neurologists and audiologists to discuss the following topics: intracranial and inner fluid interactions; the endolymph/perilymph/cerebrospinal fluid and associated disorders; non-invasive measurement of intracranial and inner fluid pressures; clinical aspects with particular reference to symptomatology, diagnosis and treatment; and comparative fluid models. Combining the clinical and research aspects of fluid and pressure regulation in the intracranial and intralabrynthine compartments as well as discussions on the clinical implications of abnormal fluid pressure is an innovative idea. The two topics have much in common. Maintaining both the intracranial pressure and the intralabrynthine pressure with normal limits is important for the normal functions of both the central nervous system and the ear. Communication between the intracranial space and the intralabrynthine space and their inter-relationships have been under-appreciated. These inter-relationships allow the possibility to measure intracranial pressure non-invasively by measuring the intralabrynthine pressure.