This book reports on the application of advanced models of the human binaural hearing system in modern technology, among others, in the following areas: binaural analysis of aural scenes, binaural de-reverberation, binaural quality assessment of audio channels, loudspeakers and performance spaces, binaural perceptual coding, binaural processing in hearing aids and cochlea implants, binaural systems in robots, binaural/tactile human-machine interfaces, speech-intelligibility prediction in rooms and/or multi-speaker scenarios. An introduction to binaural modeling and an outlook to the future are provided. Further, the book features a MATLAB toolbox to enable readers to construct their own dedicated binaural models on demand.

This book describes an exciting new movement using regenerative medicine to treat patients with otolaryngological diseases. The emerging field of regenerative medicine uses tissue engineering, which combines medicine and engineering not only to treat the diseases themselves but also to enable recovery of the function of affected areas. As otolaryngology covers wide regions, including many diseases of the head and neck, the book is divided into sections, each corresponding to a different anatomical structure - the ear, nose, oral cavity, pharynx, larynx and head and neck. The structural developments of each region, the underlying mechanisms of diseases specific to these regions, their experimental models and proposals for new regenerative treatment are all discussed in detail. The various diseases and symptoms considered in the book include inner ear and middle ear diseases, rhinitis, nasal sinusitis and otolaryngological cancers. To date there have been few clinical studies reporting regenerative medical applications in the field of otolaryngology, but in this volume leading authors present the latest research findings to help provide new therapies for patients in the future. This state-of-the-art information makes the book a valuable professional reference work for all doctors and researchers who focus on regenerative treatments in the field of otolaryngology and neuroscience.

This comprehensive volume examines the current state of free radical biology and its impact on otology, laryngology, and head and neck function. The chapters collectively highlight the interrelationship of basic and translational studies in each area, define the challenges to translation, and identify the existing basic issues that demand investigation as well as the opportunities for novel intervention to prevent and treat ENT pathology and impairment. In each chapter, or in some cases pairs of chapters, the author(s) have included or married issues of basic research with translational challenges and research, thus defining the pathway by which new basic insights may lead to interventions to prevent or treat impairment. The final chapter of this book reflects a meeting of all the contributors, culminating in a discussion and "white paper" that identifies the challenges to the field and defines the studies and collaborations that may lead to improved understanding of free radical biology in ENT and, subsequently, new interventions to medically treat ENT pathology.

This book comprehensively describes alkaptonuria and ochronosis. Beginning with the history, genetics, pathophysiology and diagnostics of the disease, the authors subsequently present a detailed characterization of its clinical manifestation in the spine, peripheral joints, eyes, ears, visceral organs and respiratory tract, its pathological anatomy and histology, as well as differential diagnosis. This is complemented by the latest data on therapy and experimental models of alkaptonuria, and supported by several case reports. Numerous pictures and radiological images document the clinical symptoms, giving the reader a solid understanding of the disease. On the basis of the editor's and authors' own extensive observations, the book offers an analysis of protein metabolism and aromatic amino acids in the context of alkaptonuria. Written by international experts in the field, the book offers a valuable reference guide for healthcare professionals working in rheumatology, dermatology, pulmonology, otolaryngology and histopathology.

Vestibular Migraine is a concise monograph that presents the scientific basis for the diagnosis and treatment of this common yet largely unrecognized cause of dizziness. Current knowledge of the features of the condition is described, and clear guidance is provided on the differentiation of vestibular migraine from other conditions that induce dizziness, including Meniere's disease. Symptomatic treatment and the various prophylactic options are discussed and evaluated, and advice is also included on long-term treatment and the circumstances under which treatment should be discontinued. Vestibular Migraine will be of interest to all physicians and other health care providers who deal with dizzy patients, including internists, family physicians, neurologists, otolaryngologists, and trainees in those specialties, as well as nurse practitioners and physician assistants.

Obstructive Sleep Apnea (OSA) is the most prevalent sleep disordered breathing disorder. It has become apparent that in more than half the patients with OSA, the frequency and duration of apneas are influenced by body position. To treat patients with Position Dependent OSA (POSA), positional therapy can be considered for preventing patients from sleeping in the worst sleeping position. Treatment of POSA has advanced dramatically recently with the introduction of a new generation of positional therapy. Positional Therapy in Obstructive Sleep Apnea presents improved OSA diagnostic methods and the tools needed to implement positional therapy in clinical practice. This includes patient work-up, positional therapy with or without other treatments, consequences of guidelines and future developments. Clinicians, students and researchers will find this comprehensive guide to be an invaluable resource for evaluating and treating sleep breathing disorders.

Robotic Surgery of the Head and Neck is the first comprehensive guide for otolaryngologists who wish to perform robotic head and neck surgery. Edited by leaders in the field, this book focuses on how improved access, visualization, and flexibility of the technology have greatly expanded the capabilities of the head and neck surgeon to treat diseases transorally or through small incisions in the skin. Starting with an overview of minimally invasive surgery in the head and neck, and moving to discussions of anatomic considerations for these procedures and the future applications of robotic surgery for otolaryngologists, Robotic Surgery of the Head and Neck explores the exciting progress of robotic technologies, bringing physicians closer to achieving the benefits of traditional surgery with the least amount of disruption to the patient.

Hearing and communication present a variety of challenges to the nervous system. To be heard and understood, a communication signal must be transformed from a time-varying acoustic waveform to a perceptual representation to an even more abstract representation that integrates memory stores with semantic/referential information. Finally, this complex, abstract representation must be interpreted to form categorical decisions that guide behavior. Did I hear the stimulus? From where and whom did it come? What does it tell me? How can I use this information to plan an action? All of these issues and questions underlie auditory cognition. Since the early 1990s, there has been a re-birth of studies that test the neural correlates of auditory cognition with a unique emphasis on the use of awake, behaving animals as model. Continuing today, how and where in the brain neural correlates of auditory cognition are formed is an intensive and active area of research. Importantly, our understanding of the role that the cortex plays in hearing has the potential to impact the next generation of cochlear- and brainstem-auditory implants and consequently help those with hearing impairments. Thus, it is timely to produce a volume that brings together this exciting literature on the neural correlates of auditory cognition. This volume compliments and extends many recent SHAR volumes such as Sound Source Localization (2005) Auditory Perception of Sound Sources (2007), and Human Auditory Cortex (2010). For example, in many of these volumes, similar issues are discussed such as auditory-object identification and perception with different emphases: in Auditory Perception of Sound Sources, authors discuss the underlying psychophysics/behavior, whereas in the Human Auditory Cortex, fMRI data are presented. The unique contribution of the proposed volume is that the authors will integrate both of these factors to highlight the neural correlates of cognition/behavior. Moreover, unlike other these other volumes, the neurophysiological data will emphasize the exquisite spatial and temporal resolution of single-neuron [as opposed to more coarse fMRI or MEG data] responses in order to reveal the elegant representations and computations used by the nervous system.

This volume contains the papers presented at the 15th International Symposium on Hearing (ISH), which was held at the Hotel Regio, Santa Marta de Tormes, Salamanca, Spain, between 1st and 5th June 2009. Since its inception in 1969, this Symposium has been a forum of excellence for debating the neurophysiological basis of auditory perception, with computational models as tools to test and unify physiological and perceptual theories. Every paper in this symposium includes two of the following: auditory physiology, psychoph- ics or modeling. The topics range from cochlear physiology to auditory attention and learning. While the symposium is always hosted by European countries, p- ticipants come from all over the world and are among the leaders in their fields. The result is an outstanding symposium, which has been described by some as a "world summit of auditory research. " The current volume has a bottom-up structure from "simpler" physiological to more "complex" perceptual phenomena and follows the order of presentations at the meeting. Parts I to III are dedicated to information processing in the peripheral au- tory system and its implications for auditory masking, spectral processing, and c- ing. Part IV focuses on the physiological bases of pitch and timbre perception. Part V is dedicated to binaural hearing. Parts VI and VII cover recent advances in und- standing speech processing and perception and auditory scene analysis. Part VIII focuses on the neurophysiological bases of novelty detection, attention, and learning.

"Phonosurgery: theory and practice" is a book that makes an impor tant contribution to the literature in laryngology. Professor Isshiki has been a driving force in the investigation and correction of certain conditions of the voice. His leadership in this field over two decades has proved to be an inspiration to those interested in the diagnosis and correction of the abnormal voice. His unique background and training in both otolaryngology and plastic surgery has provided him with fundamental knowledge and experience in the study of the voice and larynx and has given him an opportunity to utilize innovative surgical techniques in the correction of some of these problems. Professor Isshiki's name is indelibly linked with laryngeal framework surgery, and those who read this book will not be dis appointed. The book provides very adequate information on the phy siology and pathology of the voice. Emphasis is given to diagnostic aspects of abnormalities of the voice which have been made easier with the development of high technology, such as the use of the com puter and improved laryngoscopes, which include brighter lights, higher resolution lenses, and, when combined with stroboscopy and high-speed filming videolaryngoscopy, provide a valuable tool in faci litating communication between the patient, the physician, and the voice therapist.

Modern microsurgical techniques have opened up a new horizon for the otoneurosurgeon. This volume is a very important contribu tion to the student who is learning these surgical approaches. Surgical otoneurology has now passed the infancy stage, but is still an adolescent. As more otologists and neurosurgeons become skilled in this type of surgery, new and better approaches will evolve. Certainly there needs to be much better management of the carotid artery as it passes through the temporal bone. Better techniques to preserve the IX, X, and XI nerves in the jugular bulb area should be developed, and more delicate procedures for management of lesions inside the cochlea and vestibular labyrinth should be developed. As our diagnostic techniques have improved, particularly through imaging, surgical techniques to match the improved diagnostic techniques will emerge. For future otoneurologists who are pre pared, many problems involving the temporal bone that are now considered untreatable will be successfully managed for very grateful patients. The purpose of this text is to familiarize the otoneurosur geon with the anatomy of the temporal bone, skull base, infratem poral fossa, and cerebellopontine angle. This anatomy will be taught by demonstrating surgical procedures. This atlas which is an example of cooperation between the schools of Los Angeles and Verona will permit the reader to rehearse otoneurosurgical procedures in the laboratory, and, when the techniques have been mastered, apply the various approaches in the treatment of inner ear and skull base lesions. William F. House MD.

Laryngotracheal Reconstruction: From Lab to Clinic lines for using the technique of tracheal autotra- presents the experimental and clinical aspects of plantation in conservation laryngectomy. The tissue reconstruction of the larynx and trachea. shortcomings and complications of tracheal auto- The book reflects the development and implemen- transplantation encountered in the initial patient tation of a research-based clinical program. The series led to a modification of the technique. The experimental work was started in 1989 with the modified autotransplantation technique proved to aim of improving the reconstructive possibilities be reliable from a reconstructive, functional and in the following two clinical situations: (1) extend- oncological viewpoint. ed hemilaryngectomy defects after tumour In a second part (Chap. VI), healing aspects after removal and (2) tracheal stenoses that are impos- repair of laryngotracheal defects are highlighted. sible to repair by segmental tracheal resection. The The healing mechanisms of the cartilage support, two problems differ in localization (larynx, tra- the mucosal lining and the blood supply were chea), etiology (oncology, traumatic), and treat- studied for each tissue component individually.

Considered the go-to reference in airway management not only in anesthesia practice but also in emergency medicine and intensive care settings, Hagberg and Benumof's Airway Management ensures that practitioners worldwide are familiar and proficient with the most recent developments in equipment and scientific knowledge in this fast-changing area. Covering all aspects of this fundamental practice, the new 5th Edition facilitates the safe performance of airway management for all airway practitioners, regardless of specialty, using a concise, how-to approach, carefully chosen illustrations, and case examples and analysis throughout.The only volume of its kind completely dedicated to airway management, this edition features: Well-illustrated and tightly focused coverage, with anatomical drawings, charts, algorithms, photos, and imaging studies for quick reference-many new to this edition. Key Points in every chapter, as well as up-to-date information on the latest ASA guidelines. Two new chapters covering Combination Techniques and Human Factors in Airway Management; all other chapters have been thoroughly revised to reflect current thinking and practice. A significantly expanded video library, including intubating the COVID-19 patient and new videos on ultrasonography of the airway. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

The Clinician's Guide to Swallowing Fluoroscopy is a comprehensive resource for all dysphagia clinicians. This beautifully-illustrated text is intended for SLP, ENT, radiology, GI, and rehabilitation specialists interested in swallowing and addresses the need for an up-to-date, all-inclusive reference. Topics covered include radiation safety and protection, fluoroscopic oral, pharygeal, and esophageal phase protocols and abnormalities, and objective measures of timing and displacement.

We live in a complex and dynamically changing acoustic environment. To this end, the auditory cortex of humans has developed the ability to process a remarkable amount of diverse acoustic information with apparent ease. In fact, a phylogenetic comparison of auditory systems reveals that human auditory association cortex in particular has undergone extensive changes relative to that of other species, although our knowledge of this remains incomplete. In contrast to other senses, human auditory cortex receives input that is highly pre-processed in a number of sub-cortical structures; this suggests that even primary auditory cortex already performs quite complex analyses. At the same time, much of the functional role of the various sub-areas in human auditory cortex is still relatively unknown, and a more sophisticated understanding is only now emerging through the use of contemporary electrophysiological and neuroimaging techniques. The integration of results across the various techniques signify a new era in our knowledge of how human auditory cortex forms basis for auditory experience. This volume on human auditory cortex will have two major parts. In Part A, the principal methodologies currently used to investigate human auditory cortex will be discussed. Each chapter will first outline how the methodology is used in auditory neuroscience, highlighting the challenges of obtaining data from human auditory cortex; second, each methods chapter will provide two or (at most) three brief examples of how it has been used to generate a major result about auditory processing. In Part B, the central questions for auditory processing in human auditory cortex are covered. Each chapter can draw on all the methods introduced in Part A but will focus on a major computational challenge the system has to solve. This volume will constitute an important contemporary reference work on human auditory cortex. Arguably, this will be the first and most focused book on this critical neurological structure. The combination of different methodological and experimental approaches as well as a diverse range of aspects of human auditory perception ensures that this volume will inspire novel insights and spurn future research.

The new edition of this book provides an up-to-date and comprehensive overview of whiplash-associated disorders, focusing in particular on a functional approach to clinical and instrumental diagnosis and rehabilitative treatment. It fully reflects the changes in our understanding of whiplash injuries since the first edition, and in particular the increased awareness that whiplash is a whole-body trauma in which forces act progressively from the lumbar region to the brain, through the cervical spine. Detailed attention is paid to the functional connections between the sense organs of the inner ear, the sympathetic system, and the spine with a view to optimizing diagnosis and treatment. It is explained how various treatment options can be employed to best effect in patients with different symptoms, following, but updating, the well-known Quebec Task Force guidelines. Underestimated aspects such as positional vertigo, somatic tinnitus, temporomandibular disorders, and back pain are also considered. This book will be an invaluable tool in everyday clinical practice for all who are involved in the diagnosis and treatment of whiplash injury.

Perspectives on Auditory Research celebrates the last two decades of the Springer Handbook in Auditory Research. Contributions from the leading experts in the field examine the progress made in auditory research over the past twenty years, as well as the major questions for the future.

Thirty years of research into the development of hearing have produced a decent description of age-related changes in hearing as well as some understanding of the mechanisms underlying those changes. The number of potential applications of this knowledge has increased tremendously in recent years. Universal hearing screening programs make it likely that a child with a hearing loss will be identified at birth. Infants may receive hearing aids before they are six months old, and one-year-olds are receiving cochlear implants. The optimal design of device fitting strategies and habilitation techniques must be based on knowledge of auditory development and the effects of abnormal experience with sound. Moreover, there is a growing recognition of the contributions of auditory processing deficits to speech and language disorders. Again, the nature of the relationship between perception and language development must provide the basis for attempts to remediate such problems. Although recent volumes have addressed auditory development, they have focused on development in nonhuman species. Although this work is certainly informative to workers in the field of human development, it is often difficult to generalize findings from nonhumans to humans. The goal of the proposed book is to provide a basic reference for graduate students, clinicians, and researchers on fundamental principles of human auditory development, with an emphasis on the effects of auditory experience on development.

This volume will provide an important contemporary reference on hearing development and will lead to new ways of thinking about hearing in children and about remediation for children with hearing loss. Much of the material in this volume will document that a different model of hearing is needed to understand hearing during development. The book is expected to spur research in auditory development and in its application to pediatric audiology.

The hearing organs of non-mammals, which show quite large and systematic differences to each other and to those of mammals, provide an invaluable basis for comparisons of structure and function. By taking advantage of the vast diversity of possible study organisms provided by the "library" that is biological diversity, it is possible to learn how complex functions are realized in the inner ear through the evolution of specific structural, cellular and molecular configurations. Insights from Comparative Hearing Research brings together some of the most exciting comparative research on hearing and shows how this work has profoundly impacted our understanding of hearing in all vertebrates.

Under the Auspices of the Alfredo and Amalia Lacroze de Fortabat Foundation

The management of vascular and tumorous lesions of the parasellar region still remains one of the most demanding tasks in neurosurgery. It is only a short time ago that the major concepts of the anatomy of the so-called cavernous sinus were described in detail. Surgical interventions in this region are very complex, they are time-consuming and require an extensive back ground of experience in surgery of the cranial base. Pioneer anatomical studies of the parasellar region done by Taptas, and the daring direct operative approach introduced by Parkinson pro moted the development of modern neuroradiological intervention proce dures, which were initiated by Serbinenko and further refined by Debrun, Vifiuela and others. The technique of the detachable balloon catheter stimulated surgeons to proceed with the direct operative approach to lesions of the parasellar region. Today, it is hard to imagine a successful man agement of vascular pathologies of this region without a complementary use of the two techniques."

This volume is one in a series of monographs being issued under the general title of "Disorders of Human Communication." Each monograph deals in detail with a particular aspect of vocal communication and its disorders, and is written by internationally distinguished experts. Therefore, the series will provide an authoritative source of up-to-date scientific and clinical informa tion relating to the whole field of normal and abnormal speech communication, and as such will succeed the earlier monumental work "Handbuch der Stimm und Sprachheilkunde" by R. Luchsinger and G. E. Arnold (last issued in 1970). This series will prove invaluable for clinicians, teachers and research workers in phoniatrics and logopaedics, phonetics and linguistics, speech pathology, otolaryngology, neurology and neurosurgery, psychology and psychiatry, paediatrics and audiology. Several of the monographs will also be useful to voice and singing teachers, and to their pupils. G. E. Arnold, Jackson, Miss. F. Winckel, Berlin B. D. Wyke, London Preface This book tries to illustrate the practice as well as the principles involved in applying linguistics to the analysis of language disability. In writing it, I have as sumed an audience of professional speech and hearing clinicians who have had little or no formal training in linguistics. Each Chapter therefore begins with a resu me of the main theoretical and descriptive principles needed in order to carry out a clinical linguistic analysis. The relevance oflanguage acquisition studies is a major theme within this resume."