The two-volume set LNCS 4190 and LNCS 4191 constitute the refereed proceedings of the 9th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2006. The program committee carefully selected 39 revised full papers and 193 revised poster papers for presentation in two volumes. This second volume collects 118 papers related to segmentation, validation and quantitative image analysis, brain image processing, and much more.

Since their discovery by Becquerel and RAntgen, ionising radiation and detectors for ionising radiation have played an ever more important role in medical diagnostics and therapy. The use of scintillating materials in the detection of ionising radiation for medical imaging is the main topic of this book intended for an audience of physicists and engineers. The book will be useful both to new researchers entering the field and to experts interested to learn about the latest developments.

It starts with an overview of the state of the art in using radiation detectors for medical imaging, followed by an in depth discussion of all aspects of the use of scintillating materials for this application. Possibilities to improve the performance of existing scintillating materials and completely new ideas on how to use scintillating materials are discussed in detail. The first 4 chapters contain a general overview of the applications of radiation detectors in medicine and present a closer look at the 3 most important subfields, X-ray imaging, gamma ray imaging and PET. One chapter is devoted to semiconductor detectors, a promising new area, and two chapters are devoted to recent technical advances in PET. The remaining 5 chapters deal with scintillating materials and their use in medical imaging.

Advances in fluorescent proteins, live-cell imaging, and superresolution instrumentation have ushered in a new era of investigations in cell biology, medicine, and physiology. From the identification of the green fluorescent protein in the jellyfish Aequorea victoria to the engineering of novel fluorescent proteins, The Fluorescent Protein Revolution explores the history, properties, and applications of these important probes. The book first traces the history of fluorescent proteins and the revolution they enabled in cellular imaging. It then discusses fluorescent proteins with novel photophysical properties. The book also covers several cutting-edge imaging applications. These include superresolution microscopy of cellular fine structures, FRET microscopy to visualize protein interactions and cell-signaling activities inside living cells, photobleaching and photoactivation techniques to visualize protein behaviors, techniques that exploit plant and algal photoreceptors to enable light-regulated control of enzymatic activities, and the noninvasive imaging of tumor-host interactions in living animals. In color throughout, this book presents the fundamental principles and latest advances in the field, including the associated development of imaging techniques that exploit fluorescent proteins. It is accessible to a broad audience, from optical imaging experts to novices needing an introduction to the field.

The 8th International Conference on Medical Imaging and Computer Assisted Intervention, MICCAI 2005, was held in Palm Springs, California, USA, at the Riviera Resort, October 26-29, 2005. MICCAIhasbecomeapremierinternationalconferencewithin-depthpapers on the multidisciplinary ?elds of medical image computing, computer-assisted interventionandmedicalrobotics. Theconferencebringstogetherclinicians,b- logicalscientists, computer scientists, engineers,physicists and other researchers and o?ers them a forum to exchange ideas in these exciting and rapidly growing ?elds. The impact of MICCAI increases each year and the quality and quantity of submitted papers this year was very impressive. We received a record 632 full submissions (8 pages in length), an increase of 22% from 2004, from 36 di?erent countries and 5 continents (see ?g. 2). Based on a decision of the MICCAI board, this year's conference employed a double-blind review procedure on a trial basis. Our Program Committee was made up of 11 area chairs, each of whom supervised the review of almost 60 papers. Four reviews were generated for each paper from 262 reviewers and the area chairs. A ?nal paper selection meeting took place during two days in early June 2005 in Chapel Hill, North Carolina. We are especially grateful to Elizabeth Bullitt, Polina Golland, David Haynor, Rasmus Larsen, Greg Hager and Daniel Ruc .. kert, who attended this meetingandhelpedusmakethe?nalselections. MartinStynerprovidedvaluable help with information management and the Web-site, and James Stewart is acknowledgedforreliableandtimelysupportoftheWeb-basedreviewingsystem. Wearegratefultoeveryonewhoparticipatedinthe reviewprocess;theydonated a large amount of time and e?ort to make these volumes possible and insure a highlevelofquality.

With a focus on how to perform and effectively interpret pelvic ultrasound exams, Pelvic Ultrasound Imaging: A Cased-Based Application offers a unique learning experience that is ideal for ob/gyn and radiology practitioners and residents, urogynecology practitioners and fellows, diagnostic medical sonographers and those who are studying for Board exams. Current cases in gynecology and urogynecology are presented in a step-by-step format based on resident and fellow one-on-one didactic oral case reviews. An expert walk-through for each case's imaging set includes directive questions to help the reader perform proper exam assessment. This workbook: Presents cases in the way a clinical day unfolds, varied and unrelated to the previous case. Cases get progressively harder, increasingly challenging the reader's interpretation skills while moving through the text. Provides step-by-step instruction throughout, including development of 3D volume set skills, reporting nomenclature, discussion of diagnostic criteria, instrumentation topics, and clinical correlation. Highlights the importance of critically assessing, not merely diagnosing based on a presumed classic image appearance for the most common pathologies. Includes examples of common gynecology cases such as ovarian corpus luteum, hemorrhagic corpus luteum, uterine leiomyomata, endometrial polyps, and caesarean section scars, as well as more uncommon cases. Includes examples of common pelvic floor cases such as normal anal sphincter complex and thickened bladder wall, as well as more uncommon urogynecology pathologies such as rectal vaginal fistula, rectal prolapse, and mesh assessment. Walks the reader through each case with directive questions to improve diagnostic appraisal. Includes up to five images per case along with exam findings and brief clinical correlations. Provides videos on Elsevier eBooks for Practicing Clinicians that illustrate typically encountered real-time dynamic changes. Enhanced eBook version included with purchase. Your enhanced eBook allows you access to all of the text, figures, reporting templates, and references from the book on a variety of devices.

Neuroscience is an evolving, complex, and multidisciplinary field of medicine. Neuroradiologists and neuropathologists are an important part of the multidisciplinary team, in addition to neurosurgeons, neurologists, and other disciplines. Featuring over nine hundred images, this practical textbook and atlas combines the specialties of neuroradiology and neuropathology, providing an extensive understanding of the disease process. It offers a comprehensive review of the nervous system diseases, including eye, skeletal muscle, and bone and soft tissue diseases. Topics are covered in chapters arranged by region, allowing for quick reference of conditions such as brain tumors, spinal cord diseases, or congenital malformations. Introductory chapters on pathologic and radiologic techniques are also featured, enabling specialists of both areas to familiarize themselves with the other's subject. Packaged with a password to give the user online access to all the text and images, this is a must-have resource for comprehensive and accurate diagnosis.

The 7th International Conference on Medical Imaging and Computer Assisted Intervention, MICCAI 2004, was held in Saint-Malo, Brittany, France at the "Palais du Grand Large" conference center, September 26-29, 2004. The p- posaltohostMICCAI2004wasstronglyencouragedandsupportedbyIRISA, Rennes. IRISA is a publicly funded national research laboratory with a sta? of 370,including150full-timeresearchscientistsorteachingresearchscientistsand 115 postgraduate students. INRIA, the CNRS, and the University of Rennes 1 are all partners in this mixed research unit, and all three organizations were helpful in supporting MICCAI. MICCAI has become a premier international conference with in-depth - pers on the multidisciplinary ?elds of medical image computing, comput- assisted intervention and medical robotics. The conference brings together cl- icians, biological scientists, computer scientists, engineers, physicists and other researchers and o?ers them a forum to exchange ideas in these exciting and rapidly growing ?elds. The impact of MICCAI increases each year and the quality and quantity of submitted papers this year was very impressive. We received a record 516 full submissions (8 pages in length) and 101 short communications (2 pages) from 36 di?erent countries and 5 continents (see ?gures below). All submissions were reviewed by up to 4 external reviewers from the Scienti?c Review C- mittee and a primary reviewer from the Program Committee. All reviews were then considered by the MICCAI 2004 Program Committee, resulting in the acceptance of 235 full papers and 33 short communications.

Der praktische Leitfaden fur ein interdisziplinares

Management von Osophagus- und Magenkarzinomen Welche Rekonstruktionsverfahren gibt es nach Osophagusresektion?

- Wie kann man Magenfruhkarzinome lokal behandeln?

- Welche Moglichkeiten laparaskopischer Operationsverfahren gibt es?

- Wann ist eine intraoperative Strahlentherapie sinnvoll?

- Welche aktuellen Studien gibt es?

Internisten, Chirurgen und Radiologen

finden hier alle relevanten Fakten

zu den malignen Erkrankungen des oberen Gastrointestinaltrakts

- Anatomie, Atiologie und Epidemiologie

- Vorsorge und Fruherkennung

- Diagnostik, Pathologie und Stadieneinteilung

- Chirurgische Therapieverfahren

- Multimodale Therapiekonzepte

- Nachsorge und Palliativtherapie

- Prognosefaktoren

"

The 6th International Conference on Medical Imaging and Computer-Assisted Intervention,MICCAI2003,washeldinMontr eal,Qu ebec,CanadaattheF- rmont Queen Elizabeth Hotel during November 15-18, 2003. This was the ?rst time the conference had been held in Canada. The proposal to host MICCAI 2003 originated from discussions within the Ontario Consortium for Ima- guided Therapy and Surgery, a multi-institutional research consortium that was supported by the Government of Ontario through the Ontario Ministry of E- erprise, Opportunity and Innovation. The objective of the conference was to o?er clinicians and scientists a - rum within which to exchange ideas in this exciting and rapidly growing ?eld. MICCAI 2003 encompassed the state of the art in computer-assisted interv- tions, medical robotics, and medical-image processing, attracting experts from numerous multidisciplinary professions that included clinicians and surgeons, computer scientists, medical physicists, and mechanical, electrical and biome- cal engineers. The quality and quantity of submitted papers were most impressive. For MICCAI 2003 we received a record 499 full submissions and 100 short c- munications. All full submissions, of 8 pages each, were reviewed by up to 5 reviewers, and the 2-page contributions were assessed by a small subcomm- tee of the Scienti?c Review Committee. All reviews were then considered by the MICCAI 2003 Program Committee, resulting in the acceptance of 206 full papers and 25 short communications. The normal mode of presentation at MICCAI 2003 was as a poster; in addition, 49 papers were chosen for oral presentation.

The 6th International Conference on Medical Imaging and Computer-Assisted Intervention,MICCAI2003,washeldinMontr eal,Qu ebec,CanadaattheF- rmont Queen Elizabeth Hotel during November 15-18, 2003. This was the ?rst time the conference had been held in Canada. The proposal to host MICCAI 2003 originated from discussions within the Ontario Consortium for Ima- guided Therapy and Surgery, a multi-institutional research consortium that was supported by the Government of Ontario through the Ontario Ministry of E- erprise, Opportunity and Innovation. The objective of the conference was to o?er clinicians and scientists a - rum within which to exchange ideas in this exciting and rapidly growing ?eld. MICCAI 2003 encompassed the state of the art in computer-assisted interv- tions, medical robotics, and medical-image processing, attracting experts from numerous multidisciplinary professions that included clinicians and surgeons, computer scientists, medical physicists, and mechanical, electrical and biome- cal engineers. The quality and quantity of submitted papers were most impressive. For MICCAI 2003 we received a record 499 full submissions and 100 short c- munications. All full submissions, of 8 pages each, were reviewed by up to 5 reviewers, and the 2-page contributions were assessed by a small subcomm- tee of the Scienti?c Review Committee. All reviews were then considered by the MICCAI 2003 Program Committee, resulting in the acceptance of 206 full papers and 25 short communications. The normal mode of presentation at MICCAI 2003 was as a poster; in addition, 49 papers were chosen for oral presentation.

Together with the companion volume LNCS 2488 this book constitutes the refereed proceedings of the 5th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2002, held in Tokyo, Japan, in September 2002.The 184 revised full papers presented were carefully reviewed and selected from 321 submissions. The two-volume proceedings offers main topical sections on medical robotics and endoscopic devices; validation; brain tumor, cortex, vascular, and imaging and analysis; segmentation; cardiac applications; computer-assisted diagnosis; tubular structures; interventions; simulation; modelling; statistical shape modelling; image registration; visualization; and novel imaging techniques.

Together with the companion volume LNCS 2489 this book constitutes the refereed proceedings of the 5th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2002, held in Tokyo, Japan, in September 2002.The 184 revised full papers presented were carefully reviewed and selected from 321 submissions. The two-volume proceedings offers main topical sections on medical robotics and endoscopic devices; validation; brain tumor, cortex, vascular, and imaging and analysis; segmentation; cardiac applications; computer-assisted diagnosis; tubular structures; interventions; simulation; modelling; statistical shape modelling; image registration; visualization; and novel imaging techniques.

Covering the basics of X-rays, CT, PET, nuclear medicine, ultrasound, and MRI, this textbook provides senior undergraduate and beginning graduate students with a broad introduction to medical imaging. Over 130 end-of-chapter exercises are included, in addition to solved example problems, which enable students to master the theory as well as providing them with the tools needed to solve more difficult problems. The basic theory, instrumentation and state-of-the-art techniques and applications are covered, bringing students immediately up-to-date with recent developments, such as combined computed tomography/positron emission tomography, multi-slice CT, four-dimensional ultrasound, and parallel imaging MR technology. Clinical examples provide practical applications of physics and engineering knowledge to medicine. Finally, helpful references to specialised texts, recent review articles, and relevant scientific journals are provided at the end of each chapter, making this an ideal textbook for a one-semester course in medical imaging.

Dieses Buch dient der Standortbestimmung der verschiedenen Verfahren, die durch ausgewiesene Experten der verschiedenen Fachgebiete aktuell und in ubersichtlicher Form dargestellt werden. Dabei folgt einem Kapitel der interventionellen Kardiologie jeweils ein entsprechendes Kapitel der interventionellen Angiologie bzw. Radiologie, wodurch die enge Verwandtschaft, aber auch die Unterschiede leicht erkennbar werden.
Ziel der Herausgeber ist es, zum einen die interdisziplinare Diskussion anzuregen und zum anderen die Kenntnisse auerhalb des eigenen Bereiches bei gleicher Indikation zu vertiefen. Entsprechend wendet sich das Buch gleichermaen an die interventionell tatigen Kollegen der unterschiedlichen Fachrichtungen wie auch an den Allgemeinmediziner oder Internisten, der die Weichen fur eine erfolgreiche Weiterbehandlung seines Patienten stellen muss.

Exploration of Cortical Function summarizes recent research efforts aiming at the revelation of cortical population coding and signal processing strategies. Topics include optical detection techniques of population activity in the sub-millimeter range, advanced methods for the statistical analysis of these data, and biologically inspired neuronal modeling techniques for population activities in the frameworks of optimal coding, statistical learning theory, and mean-field recurrent networks.

Exploration of Cortical Function is unique in that it covers one complete branch of population-based brain research ranging from techniques for data acquisition over data analysis up to modeling techniques for the quantification of functional principles. The volume covers an area which is of great current interest to researchers working on cerebral cortex. The combination of models and image analysis techniques to examine the activity of large cohorts of neurons is especially intriguing and prone to considerable error and debate.

The intended readership is students and researchers from many disciplines, including neuroscience, biology, physics, and computer science, interested in how an interdisciplinary framework from biology advanced statistics and computational neuroscience can be used to gather a quantitative understanding of cortical function. Experimentalists may gain insight into statistical and neuronal modeling techniques, whereas theoreticians will find an introductory treatment of neuroanatomy, neurophysiology, and measurement techniques.

Clinical Imaging of the Small Intestine offers a complete review of small bowel radiology and its applications. With contributions from leading international authorities, the book provides the reader with the pertinent aspects of gastrointestinal radiology, specifically the problems of technique and interpretation that confront radiologists.The second edition was revised to include: - CT and MRI of the small bowel; - Sonography of the small bowel; - Assessing the activity of Crohn's disease with MRI; - Vascular disorders and small bowel obstructions; - Immune deficiency diseases; - Differential diagnosis based on both pathologic and radiologic findings; - New Figures and expanded index.The comprehensive scope of coverage makes this book a highly specialized but nonetheless state-of-the-art reference for those practitioners who have an interest in learning more about intestinal imaging, including radiologists, gastroenterologists and surgeons.

The 1999 international conference on Information Processing in Medical Imaging (IPMI '99) was the sixteenth in the series of biennial meetings and followed the successful meeting in Poultney, Vermont, in 1997. This year, for the rst time, the conference was held in central Europe, in the historical Hungarian town of Visegr ad, one of the most beautiful spots not only on the Danube Bend but in all Hungary. The place has many historical connections, both national and international. The castle was once a royal palace of King Matthias. In the middle ages, the Hungarian, Czech, and Polish kings met here. Recently, after the summit meeting of reestablished democracies in the area, it became a symbol for the cooperation between central European countries as they approached the European Union. It was thus also symbolic to bring IPMI, in the year of the 30th anniversary of its foundation, to this place, and organize the meeting with the close cooperation of local and traditional western organizers. It also provided a good opportunity to summarize brie?y a history of IPMI for those who were new to the IPMI conference. This year we received 82 full paper submissions from all over the world. Of these, 24 were accepted as oral presentations. These were divided into 6 sessions. In spite of our e orts, it was found to be impossible to make these sessions fully balanced and homogeneous.

In this small volume experts provide succinct answers to freuqently asked questions about the properties and handling of X-ray contrast media. It is an excellent reference source for all using these agents. Basic information is given on the development, toxicology, pharmacology, pharmacokinetics and clinical testing of contrast agents and in question and answer form on the problems and adverse events which may be associated with them. Most of the book is concerned with the most frequently used iodinated X-ray agents but there are useful sections on the magnetic resonance and ultrasound echo enhancing agents which are assuming greater and increasing importance. This book will be of interest to both radiologists and clinicians.

This fully updated, self-contained textbook covering modern optical microscopy equips students with a solid understanding of the theory underlying a range of advanced techniques. Two new chapters cover pump-probe techniques, and imaging in scattering media, and additional material throughout covers light-sheet microscopy, image scanning microscopy, and much more. An array of practical techniques are discussed, from classical phase contrast and confocal microscopy, to holographic, structured illumination, multi-photon, and coherent Raman microscopy, and optical coherence tomography. Fundamental topics are also covered, including Fourier optics, partial coherence, 3D imaging theory, statistical optics, and the physics of scattering and fluorescence. With a wealth of end-of-chapter problems, and a solutions manual for instructors available online, this is an invaluable book for electrical engineering, biomedical engineering, and physics students taking graduate courses on optical microscopy, as well as advanced undergraduates, professionals, and researchers looking for an accessible introduction to the field.

This textbook provides a comprehensive review of gynecological imaging in infancy, childhood, and adolescence. Experts from the disciplines of pediatric radiology, gynecology, surgery, and endocrinology have come together to produce a textbook that, while written primarily from the perspective of the radiologist, will be of interest to all professionals involved in the management of these patients. The normal development of the female reproductive tract is described in detail through embryological development, normal childhood appearances, and puberty. Congenital abnormalities are addressed in chapters reviewing structural abnormalities of the reproductive tract and disorders of sex development. A symptoms- based approach is followed in chapters devoted to the assessment of the patient with gynecological pain and disorders of menstruation. Disorders of the breast and the imaging of patients with gynecological neoplasia are considered in dedicated chapters. The specialty of pediatric gynecology is evolving rapidly, drawing on the skills and expertise of professionals from a wide range of specialties. This textbook should prove valuable to all who are involved in this new field of medicine.

14 contributions present mathematical models for different imaging techniques in medicine and nondestructive testing. The underlying mathematical models are presented in a way that also newcomers in the field have a chance to understand the relation between the special applications and the mathematics needed for successfully treating these problems. The reader gets an insight into a modern field of scientific computing with applications formerly not presented in such form, leading from the basics to actual research activities.

This book constitutes the refereed proceedings of the 15th International Conference on Information Processing in Medical Imaging, IPMI'97, held in Poultney, Vermont, USA, in June 1997.
The 27 revised full papers presented were selected from a total of 96 submissions; also included are 31 poster presentations. The book is divided into topical sections on shape models and matching, novel imaging methods, segmentation, image quality and statistical character of measured data, registration/mapping, statistical models in functional neuroimaging, and MR analysis and processing.

The product of 20 years of research, this book covers topics in soft tissue elasticity in vivo, from measurement techniques to clinical applications. It provides, for the first time, a single source that systematically introduces the various techniques for in vivo measurement of soft tissue elasticity in an effort to ease the difficulty between learning technical details and clinical applications of techniques. Measurement of Soft Tissue Elasticity in Vivo: Techniques and Applications presents an overview of the existing measurement methods, their physical principles, assumptions, advantages, and disadvantages. Clinical applications discussed include assessment of tissue fibrosis after radiotherapy, articular cartilage degeneration, muscle contraction, cancer staging, liver fibrosis progression, diabetic foot ulceration, cornea stiffening, and wound healing. Techniques covered include shear wave propagation methods, vibro-ultrasound methods, dynamic holography, ultrasound and other indentation methods, and OCT-based and other suction measurement methods. The book also proposes two critical directions for future research in the field. One is to standardize the terms, parameters, and test protocols used in different fields. The second proposal is to standardize one technique to dominate the field, while devices can be adapted to fit the measuring requirements of different tissues. In doing so, the results obtained for the same tissue by different clinicians can be comparable and a standardized protocol can be established. This book bridges the gap between the complexity of measuring techniques and simplicity and accuracy of their clinical use. Its comprehensiveness and clarity help new engineers in the field develop analytical methods and allow clinicians to use these techniques in their practice with greater confidence.

This book constitutes the refereed proceedings of the First Joint Conference; Computer Vision, Virtual Reality and Robotics in Medicine, CVRMed, and Medical Robotics and Computer-Assisted Surgery, MRCAS, held in Grenoble, France, in March 1997.
The volume presents 76 regular revised papers and 16 clinical papers selected from a total of 161 submitted full papers. The volume offers highly innovative and promising research results in computer-assisted medicine and medical informatics. Among the areas covered are medical imaging, virtual reality, medical robotics, and computer-integrated therapy and surgery. The book is of relevance to clinicians, medical engineers, and computer scientists.